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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow

Authors:
Maisonneuve C, Guilleret I, Vick P, Weber T, Andre P, Beyer T, Blum M, Constam DB
Citation:
Development. 2009 Sep;136(17):3019-30
Epub:
Not Epub
Abstract:
Polycystic diseases and left-right (LR) axis malformations are frequently linked to cilia defects. Renal cysts also arise in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Maisonneuve C, Guilleret I, Vick P, Weber T, Andre P, Beyer T, Blum M, Constam DB. Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow. Development. 2009 Sep;136(17):3019-30.

Carboxypeptidase A6 in Zebrafish Development and Implications for VIth Cranial Nerve Pathfinding

Authors:
Lyons PJ, Ma LH, Baker R, Fricker LD
Citation:
PLoS ONE. 2010;5(9): e12967. doi:10.1371/journal.pone.0012967
Epub:
Not Epub
Abstract:
Carboxypeptidase A6 (CPA6) is an extracellular protease that cleaves carboxy-terminal hydrophobic amino acids and has been...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lyons PJ, Ma LH, Baker R, Fricker LD. Carboxypeptidase A6 in Zebrafish Development and Implications for VIth Cranial Nerve Pathfinding. PLoS ONE. 2010;5(9): e12967. doi:10.1371/journal.pone.0012967.

Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

Authors:
Malerba A, Sharp PS, Graham IR, Arechavala-Gomeza V, Foster K, Muntoni F, Wells DJ, Dickson G
Citation:
Mol Ther. 2011 Feb;19(2):345-54. Epub 2010 Nov 23.
Epub:
Not Epub
Abstract:
The administration of antisense oligonucleotides (AOs) to skip one or more exons in mutated forms of the DMD gene and so...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Malerba A, Sharp PS, Graham IR, Arechavala-Gomeza V, Foster K, Muntoni F, Wells DJ, Dickson G. Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice. Mol Ther. 2011 Feb;19(2):345-54. Epub 2010 Nov 23..

Cloning, expression pattern and essentiality of the high-affinity copper transporter 1 (ctr1) gene in zebrafish

Authors:
Mackenzie NC, Brito M, Reyes AE, Allende ML
Citation:
Gene. 2004 Mar 17;328:113-20
Epub:
Not Epub
Abstract:
The high-affinity copper transporter 1 (Ctr1) is a highly conserved transmembrane protein that mediates the internalization of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mackenzie NC, Brito M, Reyes AE, Allende ML. Cloning, expression pattern and essentiality of the high-affinity copper transporter 1 (ctr1) gene in zebrafish. Gene. 2004 Mar 17;328:113-20.

Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe

Authors:
Luo N, Kumar A, Conwell M, Weinreb RN, Anderson R, Sun Y
Citation:
PLoS One. 2013 Jun 21;8(6):e66727. Print 2013
Epub:
Not Epub
Abstract:
Inositol phosphatases are important regulators of cell signaling, polarity, and vesicular trafficking. Mutations in OCRL, an...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luo N, Kumar A, Conwell M, Weinreb RN, Anderson R, Sun Y. Compensatory Role of Inositol 5-Phosphatase INPP5B to OCRL in Primary Cilia Formation in Oculocerebrorenal Syndrome of Lowe. PLoS One. 2013 Jun 21;8(6):e66727. Print 2013.

Crucial role of phosphatidylinositol 4-kinase IIIalpha in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling

Authors:
Ma H, Blake T, Chitnis A, Liu P, Balla T
Citation:
J Cell Sci. 2009 Nov 3. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Phosphatidylinositol 4-kinases (PI4Ks) catalyze the first committed step in the synthesis of phosphoinositides, important lipid...
Organism or Cell Type:
zebrafish
Citation Extract:
Ma H, Blake T, Chitnis A, Liu P, Balla T. Crucial role of phosphatidylinositol 4-kinase IIIalpha in development of zebrafish pectoral fin is linked to phosphoinositide 3-kinase and FGF signaling. J Cell Sci. 2009 Nov 3. [Epub ahead of print].

Cul2 is required for the activity of hypoxia-inducible factor and vasculogenesis

Authors:
Maeda Y, Suzuki T, Pan X, Chen G, Pan S, Bartman T, Whitsett JA
Citation:
J Biol Chem. 2008 Jun 6;283(23):16084-92. Epub 2008 Mar 27.
Epub:
Not Epub
Abstract:
CULLIN 2 (CUL2) is a component of the ElonginB/C-CUL2-RBX-1-Von Hippel-Lindau (VHL) tumor suppressor complex that ubiquitinates...
Organism or Cell Type:
zebrafish
Citation Extract:
Maeda Y, Suzuki T, Pan X, Chen G, Pan S, Bartman T, Whitsett JA. Cul2 is required for the activity of hypoxia-inducible factor and vasculogenesis. J Biol Chem. 2008 Jun 6;283(23):16084-92. Epub 2008 Mar 27..

Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish

Authors:
Ma L, Yu YM, Guo Y, Hart RP, Schachner M
Citation:
Eur J Neurosci. 2012 Feb;35(3):353-65. doi: 10.1111/j.1460-9568.2011.07958.x
Epub:
Not Epub
Abstract:
In contrast to mammals, adult zebrafish have the ability to regrow descending axons and gain locomotor recovery after spinal...
Organism or Cell Type:
zebrafish
Citation Extract:
Ma L, Yu YM, Guo Y, Hart RP, Schachner M. Cysteine- and glycine-rich protein 1a is involved in spinal cord regeneration in adult zebrafish. Eur J Neurosci. 2012 Feb;35(3):353-65. doi: 10.1111/j.1460-9568.2011.07958.x.

DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish

Authors:
Mahler J, Filippi A, Driever W
Citation:
J Neurosci. 2010 Dec 8;30(49):16621-35; doi:10.1523/JNEUROSCI.4769-10.2010
Epub:
Not Epub
Abstract:
Dopaminergic neurons develop at distinct anatomical sites to form some of the major neuromodulatory systems in the vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahler J, Filippi A, Driever W. DeltaA/DeltaD Regulate Multiple and Temporally Distinct Phases of Notch Signaling during Dopaminergic Neurogenesis in Zebrafish. J Neurosci. 2010 Dec 8;30(49):16621-35; doi:10.1523/JNEUROSCI.4769-10.2010.

Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity

Authors:
Mahuzier A, Gaudé HM, Grampa V, Anselme I, Silbermann F, Leroux-Berger M, Delacour D, Ezan J, Montcouquiol M, Saunier S, Schneider-Maunoury S, Vesque C
Citation:
J Cell Biol. 2012 Aug 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Cilia are at the core of planar polarity cellular events in many systems. However, the molecular mechanisms by which they...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahuzier A, Gaudé HM, Grampa V, Anselme I, Silbermann F, Leroux-Berger M, Delacour D, Ezan J, Montcouquiol M, Saunier S, Schneider-Maunoury S, Vesque C. Dishevelled stabilization by the ciliopathy protein Rpgrip1l is essential for planar cell polarity. J Cell Biol. 2012 Aug 27. [Epub ahead of print].

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