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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model
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Citation:
Nat Med. 2012;[Epub ahead of print] doi:/10.1038/nm.2860 Epub:
Not Epub Abstract:
Cilia are evolutionarily conserved microtubule-based organelles that are crucial for diverse biological functions, including... Organism or Cell Type:
zebrafish Citation Extract: McIntyre JC, Davis E, Joiner A, Williams CL, Tsai IC, Jenkins PM, McEwen DP, Zhang L, Escobado J, Thomas S, Szymanska K, Johnson CA, Beales PL, Green ED, Mullikin JC, NISC Comparative Sequencing Program, Sabo A, Muzny DM, Gibbs RA, Attie-Bitach T, Yoder BK, Reed RR, Katsanis N, Martens J . Gene therapy rescues cilia defects and restores olfactory function in a mammalian ciliopathy model. Nat Med. 2012;[Epub ahead of print] doi:/10.1038/nm.2860. |
Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent
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Citation:
Dev Biol. 2009 Apr 15;328(2):342-54. Epub 2009 Feb 4 Epub:
Not Epub Abstract:
Primordial germ cells (PGCs) are the progenitors of reproductive cells in metazoans and are an important model for the study of... Delivery Method:
Microinjection Organism or Cell Type:
Zebrafish (lit. review) Citation Extract: Mich JK, Blaser H, Thomas NA, Firestone AJ, Yelon D, Raz E, Chen JK. Germ cell migration in zebrafish is cyclopamine-sensitive but Smoothened-independent. Dev Biol. 2009 Apr 15;328(2):342-54. Epub 2009 Feb 4. |
Glucosylceramide transferase activity is critical for encystation and viable cyst production by an intestinal protozoan, Giardia lamblia
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Citation:
J Biol Chem. 2013;[Epub ahead of print] doi:10.1074/jbc.M112.438416 Epub:
Not Epub Abstract:
The production of viable cysts by Giardia is essential for its survival in the environment and spreading the infection via... Delivery Method:
Electroporation Organism or Cell Type:
Giardia lamblia Citation Extract: Mendez TL, Chatterjee AD, Duarte TT, Gazos-Lopes F, Robles-Martinez L, Roy D, Sun J, Maldonado RA, Roychowdhury S, Almeida IC, Das S. Glucosylceramide transferase activity is critical for encystation and viable cyst production by an intestinal protozoan, Giardia lamblia. J Biol Chem. 2013;[Epub ahead of print] doi:10.1074/jbc.M112.438416 . |
Glycine receptors regulate interneuron differentiation during spinal network development
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Citation:
Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9679-84. Epub 2006 Jun 8 Epub:
Not Epub Abstract:
Glycinergic and GABAergic excitatory chloride-mediated signaling is often the first form of activity to emerge in the nascent... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: McDearmid JR, Liao M, Drapeau P. Glycine receptors regulate interneuron differentiation during spinal network development. Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9679-84. Epub 2006 Jun 8. |
Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation
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Citation:
Development. 2012 Aug;139(15):2740-50. doi: 10.1242/dev.076075. Epub 2012 Jun 28 Epub:
Not Epub Abstract:
Pax gene haploinsufficiency causes a variety of congenital defects. Renal-coloboma syndrome, resulting from mutations in Pax2,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: McCarroll MN, Lewis ZR, Culbertson MD, Martin BL, Kimelman D, Nechiporuk AV. Graded levels of Pax2a and Pax8 regulate cell differentiation during sensory placode formation. Development. 2012 Aug;139(15):2740-50. doi: 10.1242/dev.076075. Epub 2012 Jun 28. |
Growth differentiation factor-9 signaling in the ovary
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Citation:
Mol Cell Endocrinol. 2003 Apr 28;202(1-2):31-6 Epub:
Not Epub Abstract:
Growth differentiation factor-9 (GDF-9) is an oocyte-derived growth factor and a member of the transforming growth factor-beta... Delivery Method:
not published Organism or Cell Type:
Mouse embryo Citation Extract: Mazerbourg S, Hsueh AJ. Growth differentiation factor-9 signaling in the ovary. Mol Cell Endocrinol. 2003 Apr 28;202(1-2):31-6. |
Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins
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Citation:
J Biol Chem. 2012 Jan 27;287(5):2971-83. doi: 10.1074/jbc.M111.308312. Epub 2011 Nov 29 Epub:
Not Epub Abstract:
α-Synuclein is strongly implicated in the pathogenesis of Parkinson disease. However, the normal functions of synucleins and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Milanese C, Sager JJ, Bai Q, Farrell TC, Cannon JR, Greenamyre JT, Burton EA. Hypokinesia and reduced dopamine levels in zebrafish lacking β- and γ1-synucleins. J Biol Chem. 2012 Jan 27;287(5):2971-83. doi: 10.1074/jbc.M111.308312. Epub 2011 Nov 29. |
Identification of chaperonin CCTgamma subunit as a determinant of retinotectal development by whole-genome subtraction cloning from zebrafish no tectal neuron mutant
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Citation:
Development. 2004 May;131(9):1913-25. Epub:
Not Epub Abstract:
Zebrafish no tectal neuron (ntn) mutant obtained by trimethylpsoralen (TMP) mutagenesis showed defects in tectal neuropil... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Matsuda N, Mishina M. Identification of chaperonin CCTgamma subunit as a determinant of retinotectal development by whole-genome subtraction cloning from zebrafish no tectal neuron mutant. Development. 2004 May;131(9):1913-25.. |
Induced dystrophin exon skipping in human muscle explants
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Citation:
Neuromuscul Disord. 2006 Oct;16(9-10):583-90. Epub 2006 Aug 21 Epub:
Not Epub Abstract:
Antisense oligonucleotide (AO) manipulation of pre-mRNA splicing of the dystrophin gene is showing promise in overcoming... Delivery Method:
peptide-coupled Organism or Cell Type:
muscle explants, mouse and human Citation Extract: McClorey G, Fall AM, Moulton HM, Iversen PL, Rasko JE, Ryan M, Fletcher S, Wilton SD. Induced dystrophin exon skipping in human muscle explants. Neuromuscul Disord. 2006 Oct;16(9-10):583-90. Epub 2006 Aug 21. |
Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome
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Citation:
Development. 2011 Feb;138(4):755-65. doi: 10.1242/dev.062521. Erratum in: Development. 2012 May;139(10):1885 Epub:
Not Epub Abstract:
Different levels and timing of Hedgehog (Hh) signalling activity have been proposed to specify three distinct cell types in the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Maurya AK, Tan H, Souren M, Wang X, Wittbrodt J, Ingham PW. Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome. Development. 2011 Feb;138(4):755-65. doi: 10.1242/dev.062521. Erratum in: Development. 2012 May;139(10):1885. |