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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12371 scientific papers returned from the database with the search filters currently being used below.

A requirement for kit in embryonic zebrafish melanocyte differentiation is revealed by melanoblast delay

Authors:
Mellgren EM, Johnson SL
Citation:
Dev Genes Evol. 2004 Oct;214(10):493-502.
Epub:
Not Epub
Abstract:
Exploring differences in gene requirements between species can allow us to delineate basic developmental mechanisms, provide...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mellgren EM, Johnson SL. A requirement for kit in embryonic zebrafish melanocyte differentiation is revealed by melanoblast delay. Dev Genes Evol. 2004 Oct;214(10):493-502..

A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway

Authors:
Matluk N, Rochiera JA, Karaczyn A, Adams TL, Verdi JM
Citation:
BMC Biol. 2010 Jan 25;8(1):7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: Previous studies have linked neurotrophin receptor-interacting MAGE protein to the bone morphogenic...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HEK293
Citation Extract:
Matluk N, Rochiera JA, Karaczyn A, Adams TL, Verdi JM. A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway. BMC Biol. 2010 Jan 25;8(1):7. [Epub ahead of print].

A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3

Authors:
McCollum CW, Amin SR, Pauerstein P, Lane ME
Citation:
Dev Biol. 2007 Sep 15;309(2):373-85. Epub 2007 Jul 12
Epub:
Not Epub
Abstract:
The Six3 and Rx3 homeodomain proteins are essential for the specification and proliferation of forebrain and retinal precursor...
Organism or Cell Type:
zebrafish
Citation Extract:
McCollum CW, Amin SR, Pauerstein P, Lane ME. A zebrafish LMO4 ortholog limits the size of the forebrain and eyes through negative regulation of six3b and rx3. Dev Biol. 2007 Sep 15;309(2):373-85. Epub 2007 Jul 12.

Agonistic and Antagonistic Roles for TNIK and MINK in Non-Canonical and Canonical Wnt Signalling

Authors:
Mikryukov A, Moss T
Citation:
PLoS ONE. 2012;7(9):e43330. doi:10.1371/journal.pone.0043330
Epub:
Not Epub
Abstract:
Wnt signalling is a key regulatory factor in animal development and homeostasis and plays an important role in the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mikryukov A, Moss T. Agonistic and Antagonistic Roles for TNIK and MINK in Non-Canonical and Canonical Wnt Signalling. PLoS ONE. 2012;7(9):e43330. doi:10.1371/journal.pone.0043330.

Albumin-based nanoconjugates for targeted delivery of therapeutic oligonucleotides

Authors:
Ming X, Carver K, Wu L
Citation:
Biomaterials. 2013 Oct;34(32):7939-49. doi: 10.1016/j.biomaterials.2013.06.066. Epub 2013 Jul 19.
Epub:
Not Epub
Abstract:
Nanoparticle-based delivery has become an important strategy to advance siRNA and antisense oligonucleotides into clinical...
Delivery Method:
Nanoparticle
Organism or Cell Type:
cell culture
Citation Extract:
Ming X, Carver K, Wu L. Albumin-based nanoconjugates for targeted delivery of therapeutic oligonucleotides. Biomaterials. 2013 Oct;34(32):7939-49. doi: 10.1016/j.biomaterials.2013.06.066. Epub 2013 Jul 19..

Alpha-cardiac actin mutations produce atrial septal defects

Authors:
Matsson H, Eason J, Bookwalter CS, Klar J, Gustavsson P, Sunnegardh J, Enell H, Jonzon A, Vikkula M, Gutierrez I, Riveron JG, Pope M, Bu'lock F, Cox J, Robinson TE, Song F, Brook JD, Marston S, Trybus KM, Dahl N
Citation:
Hum Mol Genet. 2008 Jan 15;17(2):256-65. Epub 2007 Oct 18
Epub:
Not Epub
Abstract:
Atrial septal defect (ASD) is one of the most frequent congenital heart defects (CHD) with a variable phenotypic effect...
Organism or Cell Type:
chick embryo
Citation Extract:
Matsson H, Eason J, Bookwalter CS, Klar J, Gustavsson P, Sunnegardh J, Enell H, Jonzon A, Vikkula M, Gutierrez I, Riveron JG, Pope M, Bu'lock F, Cox J, Robinson TE, Song F, Brook JD, Marston S, Trybus KM, Dahl N. Alpha-cardiac actin mutations produce atrial septal defects. Hum Mol Genet. 2008 Jan 15;17(2):256-65. Epub 2007 Oct 18.

Amyloid-β Inhibits No-cGMP Signaling in a CD36- and CD47-Dependent Manner

Authors:
Miller TW, Isenberg JS, Shih HB, Wang Y, Roberts DD
Citation:
PLoS ONE. 2010;5(12): e15686. doi:10.1371/journal.pone.0015686
Epub:
Not Epub
Abstract:
Amyloid-β interacts with two cell surface receptors, CD36 and CD47, through which the matricellular protein thrombospondin-1...
Organism or Cell Type:
cell culture: BAEC and Jurkat
Citation Extract:
Miller TW, Isenberg JS, Shih HB, Wang Y, Roberts DD. Amyloid-β Inhibits No-cGMP Signaling in a CD36- and CD47-Dependent Manner. PLoS ONE. 2010;5(12): e15686. doi:10.1371/journal.pone.0015686.

An Essential and Evolutionarily Conserved Role of Protein Arginine Methyltransferase 1 for Adult Intestinal Stem Cells During Postembryonic Development

Authors:
Matsuda H, Shi YB
Citation:
Stem Cells. 2010 Sep 16. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Organ-specific adult stem cells are critical for the homeostasis of adult organs and organ repair and regeneration....
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Matsuda H, Shi YB. An Essential and Evolutionarily Conserved Role of Protein Arginine Methyltransferase 1 for Adult Intestinal Stem Cells During Postembryonic Development. Stem Cells. 2010 Sep 16. [Epub ahead of print].

An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation.

Authors:
Matsuo-Takasaki M, Matsumura M, Sasai Y.
Citation:
Development. 2005 Sep;132(17):3885-94. Epub 2005 Aug 3.
Epub:
Not Epub
Abstract:
During gastrulation in Xenopus, the head ectoderm is subdivided into the central nervous system (CNS) anlage (neural plate) and...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Matsuo-Takasaki M, Matsumura M, Sasai Y.. An essential role of Xenopus Foxi1a for ventral specification of the cephalic ectoderm during gastrulation.. Development. 2005 Sep;132(17):3885-94. Epub 2005 Aug 3..

Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD

Authors:
McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD
Citation:
Gene Ther. 2006 Oct;13(19):1373-81. Epub 2006 May 25
Epub:
Not Epub
Abstract:
Manipulation of pre-mRNA splicing by antisense oligonucleotides (AOs) offers considerable potential for a number of genetic...
Delivery Method:
Bathing primary cell culture, with and without peptide conjugates
Organism or Cell Type:
cell culture: primary myoblasts, golden retreiver DMD model
Citation Extract:
McClorey G, Moulton HM, Iversen PL, Fletcher S, Wilton SD. Antisense oligonucleotide-induced exon skipping restores dystrophin expression in vitro in a canine model of DMD. Gene Ther. 2006 Oct;13(19):1373-81. Epub 2006 May 25.

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