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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development

Authors:
Luo T, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD
Citation:
Development. 2007 Apr;134(7):1279-89. Epub 2007 Feb 21.
Epub:
Not Epub
Abstract:
Inca (induced in neural crest by AP2) is a novel protein discovered in a microarray screen for genes that are upregulated in...
Citation Extract:
Luo T, Xu Y, Hoffman TL, Zhang T, Schilling T, Sargent TD. Inca: a novel p21-activated kinase-associated protein required for cranial neural crest development. Development. 2007 Apr;134(7):1279-89. Epub 2007 Feb 21..

Induction of neural crest in Xenopus by transcription factor AP2{alpha}

Authors:
Luo T, Lee YH, Saint-Jeannet JP, Sargent TD
Citation:
Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):532-7. Epub 2003 Jan 02
Epub:
Not Epub
Abstract:
We report experiments with Xenopus laevis, using both intact embryos and ectodermal explants, showing that the transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Luo T, Lee YH, Saint-Jeannet JP, Sargent TD. Induction of neural crest in Xenopus by transcription factor AP2{alpha}. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):532-7. Epub 2003 Jan 02.

Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers

Authors:
Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M
Citation:
Arch Virol. 2008 May;153(5):929-37. Epub 2008 Mar 28
Epub:
Not Epub
Abstract:
New methods to combat influenza A virus (FLUAV) in humans and animals are needed. The H3N8 subtype virus was the cause of the...
Delivery Method:
Peptide-coupled intranasal
Organism or Cell Type:
mice
Citation Extract:
Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M. Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers. Arch Virol. 2008 May;153(5):929-37. Epub 2008 Mar 28.

Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs

Authors:
Ma W, Lin Y, Xuan W, Iversen PL, Smith LJ, Benchimol S
Citation:
Oncogene. 2011 [Epub ahead of print 18 July] doi: 10.1038/onc.2011.300
Epub:
Not Epub
Abstract:
The p53 tumor suppressor gene encodes a transcription factor that is commonly mutated in cancer. Tumors arise when premalignant...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: H460
Citation Extract:
Ma W, Lin Y, Xuan W, Iversen PL, Smith LJ, Benchimol S. Inhibition of p53 expression by peptide-conjugated phosphorodiamidate morpholino oligomers sensitizes human cancer cells to chemotherapeutic drugs. Oncogene. 2011 [Epub ahead of print 18 July] doi: 10.1038/onc.2011.300.

Jagged2a-notch signaling mediates cell fate choice in the zebrafish pronephric duct

Authors:
Ma M, Jiang YJ
Citation:
PLoS Genet. 2007 Jan 26;3(1):e18
Epub:
Not Epub
Abstract:
Pronephros, a developmental model for adult mammalian kidneys (metanephros) and a functional kidney in early teleosts, consists...
Organism or Cell Type:
zebrafish
Citation Extract:
Ma M, Jiang YJ. Jagged2a-notch signaling mediates cell fate choice in the zebrafish pronephric duct. PLoS Genet. 2007 Jan 26;3(1):e18.

KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome

Authors:
Lyons DA, Naylor SG, Mercurio S, Dominguez C, Talbot WS
Citation:
Development. 2008 Feb;135(3):599-608
Epub:
Not Epub
Abstract:
Mutations in Kif1-binding protein/KIAA1279 (KBP) cause the devastating neurological disorder Goldberg-Shprintzen syndrome (GSS...
Organism or Cell Type:
zebrafish
Citation Extract:
Lyons DA, Naylor SG, Mercurio S, Dominguez C, Talbot WS. KBP is essential for axonal structure, outgrowth and maintenance in zebrafish, providing insight into the cellular basis of Goldberg-Shprintzen syndrome. Development. 2008 Feb;135(3):599-608.

Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons

Authors:
Lyons DA, Naylor SG, Scholze A, Talbot WS
Citation:
Nat Genet. 2009 Jul;41(7):854-8. Epub 2009 Jun 7
Epub:
Not Epub
Abstract:
The kinesin motor protein Kif1b has previously been implicated in the axonal transport of mitochondria and synaptic vesicles....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lyons DA, Naylor SG, Scholze A, Talbot WS. Kif1b is essential for mRNA localization in oligodendrocytes and development of myelinated axons. Nat Genet. 2009 Jul;41(7):854-8. Epub 2009 Jun 7.

Killing the messenger: The role of CXCR7 in regulating primordial germ cell migration

Authors:
Mahabaleshwar H, Boldajipour B, Raz E
Citation:
Cell Adh Migr. 2008 Apr;2(2):69-70. Epub 2008 Apr 3
Epub:
Not Epub
Abstract:
Primordial Germ Cell (PGC) migration in zebrafish is guided by SDF-1a. Binding of this chemokine to its receptor CXCR4b...
Organism or Cell Type:
zebrafish
Citation Extract:
Mahabaleshwar H, Boldajipour B, Raz E. Killing the messenger: The role of CXCR7 in regulating primordial germ cell migration. Cell Adh Migr. 2008 Apr;2(2):69-70. Epub 2008 Apr 3.

Laser-scanning velocimetry: A confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae

Authors:
Malone MH, Sciaky N, Stalheim L, Hahn KM, Linney E, Johnson GL
Citation:
BMC Biotechnol. 2007 Jul 10;7(1):40 [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: BACKGROUND: The zebrafish Danio rerio is an important model system for drug discovery and to study cardiovascular...
Organism or Cell Type:
zebrafish
Citation Extract:
Malone MH, Sciaky N, Stalheim L, Hahn KM, Linney E, Johnson GL. Laser-scanning velocimetry: A confocal microscopy method for quantitative measurement of cardiovascular performance in zebrafish embryos and larvae. BMC Biotechnol. 2007 Jul 10;7(1):40 [Epub ahead of print].

Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity

Authors:
Malerba A, Boldrin L, Dickson G
Citation:
Nucleic Acid Ther. 2011 Aug;21(4):293-8
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is a lethal X-linked inherited disease caused by mutations in the dystrophin gene and...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Malerba A, Boldrin L, Dickson G. Long-term systemic administration of unconjugated morpholino oligomers for therapeutic expression of dystrophin by exon skipping in skeletal muscle: implications for cardiac muscle integrity. Nucleic Acid Ther. 2011 Aug;21(4):293-8.

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