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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12158 scientific papers returned from the database with the search filters currently being used below.

Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements

Authors:
Marlow F, Topczewski J, Sepich D, Solnica-Krezel L
Citation:
Curr Biol 2002 Jun 4;12(11):876-84
Epub:
Not Epub
Abstract:
BACKGROUND: During vertebrate gastrulation convergence and extension (CE), movements narrow and lengthen embryonic tissues. In...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marlow F, Topczewski J, Sepich D, Solnica-Krezel L. Zebrafish Rho kinase 2 acts downstream of Wnt11 to mediate cell polarity and effective convergence and extension movements. Curr Biol 2002 Jun 4;12(11):876-84.

Integrating zebrafish toxicology and green nanoscience for safer product development.

Authors:
Kim KT, Tanguay R
Citation:
Green Chem. 2013;[Epub ahead of print] doi:10.1039/C3GC36806H
Epub:
Not Epub
Abstract:
The design, manufacture and application of safer products and manufacturing processes have been important goals over the last...
Citation Extract:
Kim KT, Tanguay R. Integrating zebrafish toxicology and green nanoscience for safer product development.. Green Chem. 2013;[Epub ahead of print] doi:10.1039/C3GC36806H.

(-)-Epigallocatechin-3-gallate induces Du145 prostate cancer cell death via downregulation of inhibitor of DNA binding 2, a dominant negative helix-loop-helix protein

Authors:
Luo KL, Luo JH, Yu YP
Citation:
Cancer Sci. 2009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
(-)-Epigallocatechin-3-gallate (EGCG) is one of the major polyphenol components in green tea. It effectively induces apoptosis...
Organism or Cell Type:
cell culture: human prostate cancer cell line Du145
Citation Extract:
Luo KL, Luo JH, Yu YP. (-)-Epigallocatechin-3-gallate induces Du145 prostate cancer cell death via downregulation of inhibitor of DNA binding 2, a dominant negative helix-loop-helix protein. Cancer Sci. 2009. [Epub ahead of print].

9-Cis-Retinoic Acid Induces Growth Inhibition in Retinoid-Sensitive Breast Cancer and Sea Urchin Embryonic Cells via Retinoid X Receptor α and Replication Factor C3

Authors:
Maeng S, Kim GJ, Choi EJ, Yang HO, Lee DS, Sohn YC
Citation:
Mol Endocrinol. 2012 Nov;26(11):1821-35. doi: 10.1210/me.2012-1104. Epub 2012 Sep 4
Epub:
Not Epub
Abstract:
There is widespread interest in defining factors and mechanisms that suppress the proliferation of cancer cells. Retinoic acid...
Organism or Cell Type:
Sea urchin, Strongylocentrotus nudus
Citation Extract:
Maeng S, Kim GJ, Choi EJ, Yang HO, Lee DS, Sohn YC. 9-Cis-Retinoic Acid Induces Growth Inhibition in Retinoid-Sensitive Breast Cancer and Sea Urchin Embryonic Cells via Retinoid X Receptor α and Replication Factor C3. Mol Endocrinol. 2012 Nov;26(11):1821-35. doi: 10.1210/me.2012-1104. Epub 2012 Sep 4.

A DEAB-sensitive aldehyde dehydrogenase regulates hematopoietic stem and progenitor cells development during primitive hematopoiesis in zebrafish embryos

Authors:
Ma AC, Chung MI, Liang R, Leung AY
Citation:
Leukemia. 2010 Oct 7. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Although aldehyde dehydrogenase (ALDH) activity has become a surrogate of hematopoietic stem and progenitor cells (HSPCs), its...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma AC, Chung MI, Liang R, Leung AY. A DEAB-sensitive aldehyde dehydrogenase regulates hematopoietic stem and progenitor cells development during primitive hematopoiesis in zebrafish embryos. Leukemia. 2010 Oct 7. [Epub ahead of print].

A novel zebrafish jak2a(V581F) model shared features of human JAK2(V617F) polycythemia vera

Authors:
Ma AC, Fan A, Ward AC, Liongue C, Lewis RS, Cheng SH, Chan PK, Yip SF, Liang R, Leung AY
Citation:
Exp Hematol. 2009 Sep 19. [Epub ahead of print]
Epub:
Not Epub
Abstract:
OBJECTIVE: The Janus kinase 2 (JAK2) is important for embryonic primitive hematopoiesis. A gain-of-function JAK2 (JAK2(V617F))...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ma AC, Fan A, Ward AC, Liongue C, Lewis RS, Cheng SH, Chan PK, Yip SF, Liang R, Leung AY. A novel zebrafish jak2a(V581F) model shared features of human JAK2(V617F) polycythemia vera. Exp Hematol. 2009 Sep 19. [Epub ahead of print].

A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation

Authors:
Mahmood M, Fu S, Cooke J, Wilson SW, Cooper JD, Russell C
Citation:
Brain. 2013;[Epub ahead of print] doi:10.1093/brain/awt043
Epub:
Not Epub
Abstract:
Tripeptidyl peptidase 1 (TPP1) deficiency causes CLN2 disease, late infantile (or classic late infantile neuronal ceroid...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahmood M, Fu S, Cooke J, Wilson SW, Cooper JD, Russell C. A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation. Brain. 2013;[Epub ahead of print] doi:10.1093/brain/awt043 .

A {beta}1,4-galactosyltransferase is required for Bmp2-dependent patterning of the dorsoventral axis during zebrafish embryogenesis

Authors:
Machingo QJ, Fritz A, Shur BD
Citation:
Development. 2006 Jun;133(11):2233-41. Epub 2006 May 3.
Epub:
Not Epub
Abstract:
Complex carbohydrates are highly polymorphic macromolecules that are involved in diverse biological processes; however, a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Machingo QJ, Fritz A, Shur BD. A {beta}1,4-galactosyltransferase is required for Bmp2-dependent patterning of the dorsoventral axis during zebrafish embryogenesis. Development. 2006 Jun;133(11):2233-41. Epub 2006 May 3..

A {beta}1,4-galactosyltransferase is required for convergent extension movements in zebrafish

Authors:
Machingo QJ, Fritz A, Shur BD
Citation:
Dev Biol. 2006 Sep 15;297(2):471-82. Epub 2006 May 27
Epub:
Not Epub
Abstract:
Our understanding of how complex carbohydrates function during embryonic development is still very limited, primarily due to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Machingo QJ, Fritz A, Shur BD. A {beta}1,4-galactosyltransferase is required for convergent extension movements in zebrafish. Dev Biol. 2006 Sep 15;297(2):471-82. Epub 2006 May 27.

Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals

Authors:
Lynch VJ, Tanzer A, Wang Y, Leung FC, Gellersen B, Emera D, Wagner GP
Citation:
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14928-33. Epub 2008 Sep 22
Epub:
Not Epub
Abstract:
Evolutionary change in gene regulation can result from changes in cis-regulatory elements, leading to differences in the...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: CRL-4003 immortalized human endometrial stromal
Citation Extract:
Lynch VJ, Tanzer A, Wang Y, Leung FC, Gellersen B, Emera D, Wagner GP. Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14928-33. Epub 2008 Sep 22.

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