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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Sphingosine 1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning

Authors:
Mendelson K, Zygmunt T, Torres-Vazquez J, Evans T, Hla T
Citation:
J Biol Chem. 2013 January 25; 288(4): 2143–2156.
Epub:
Not Epub
Abstract:
Sphingosine 1-phosphate (S1P) binds G-protein-coupled receptors (S1P1–5) to regulate a multitude of physiological effects,...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3554887/
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mendelson K, Zygmunt T, Torres-Vazquez J, Evans T, Hla T. Sphingosine 1-Phosphate Receptor Signaling Regulates Proper Embryonic Vascular Patterning. J Biol Chem. 2013 January 25; 288(4): 2143–2156. .

Src modulates contractile vascular smooth muscle function via regulation of focal adhesions

Authors:
Min J, Reznichenko M, Poythress RH, Gallant CM, Vetterkind S, Li Y, Morgan KG
Citation:
J Cell Physiol. 2012;227(11):3585-92. http://dx.doi.org/10.1002/jcp.24062
Epub:
Not Epub
Abstract:
Src is a known regulator of focal adhesion turnover in migrating cells; but, in contrast, Src is generally assumed to play...
Citation Extract:
Min J, Reznichenko M, Poythress RH, Gallant CM, Vetterkind S, Li Y, Morgan KG. Src modulates contractile vascular smooth muscle function via regulation of focal adhesions. J Cell Physiol. 2012;227(11):3585-92. http://dx.doi.org/10.1002/jcp.24062.

Sulf1 modulates BMP signaling and is required for somite morphogenesis and development of the horizontal myoseptum

Authors:
Meyers J, Planamento J, Ebrom P, Krulewitz N, Wade E, Pownall ME
Citation:
Dev Biol. 2013 Apr 10. doi:pii: S0012-1606(13)00168-1. 10.1016/j.ydbio.2013.04.002. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Heparan sulfate proteoglycans (HSPGs) are glycosylated extracellular or membrane-associated proteins. Their unbranched heparan...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meyers J, Planamento J, Ebrom P, Krulewitz N, Wade E, Pownall ME. Sulf1 modulates BMP signaling and is required for somite morphogenesis and development of the horizontal myoseptum. Dev Biol. 2013 Apr 10. doi:pii: S0012-1606(13)00168-1. 10.1016/j.ydbio.2013.04.002. [Epub ahead of print].

Systematic discovery of nonobvious human disease models through orthologous phenotypes

Authors:
McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM
Citation:
Proc Natl Acad Sci U S A. 2010 Mar 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Biologists have long used model organisms to study human diseases, particularly when the model bears a close resemblance to the...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
McGary KL, Park TJ, Woods JO, Cha HJ, Wallingford JB, Marcotte EM. Systematic discovery of nonobvious human disease models through orthologous phenotypes. Proc Natl Acad Sci U S A. 2010 Mar 22. [Epub ahead of print].

Targeted 'knockdown' of spliceosome function in mammalian cells

Authors:
Matter N, Konig H
Citation:
Nucleic Acids Res. 2005 Feb 24;33(4):e41
Epub:
Not Epub
Abstract:
The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions--...
Delivery Method:
Electroporation
Organism or Cell Type:
Cell Culture: EL4 Cells and Jurkat cells
Citation Extract:
Matter N, Konig H. Targeted 'knockdown' of spliceosome function in mammalian cells. Nucleic Acids Res. 2005 Feb 24;33(4):e41.

Tetraspanin, CD151, is required for maintenance of trigeminal placode identity

Authors:
McCabe KL, Bronner M
Citation:
J Neurochem. 2011 Apr;117(2):221-30. doi: 10.1111/j.1471-4159.2011.07190.x. Epub 2011 Feb 24
Epub:
Not Epub
Abstract:
The trigeminal ganglion is the largest of the cranial ganglia and responsible for transmitting sensory information for much of...
Delivery Method:
Electroporation
Organism or Cell Type:
chick embryo
Citation Extract:
McCabe KL, Bronner M. Tetraspanin, CD151, is required for maintenance of trigeminal placode identity. J Neurochem. 2011 Apr;117(2):221-30. doi: 10.1111/j.1471-4159.2011.07190.x. Epub 2011 Feb 24.

The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo

Authors:
Min TH, Kriebel M, Hou S, Pera EM
Citation:
Dev Biol. 2011 Oct 1;358(1):262-76. doi: 10.1016/j.ydbio.2011.07.035. Epub 2011 Aug 4
Epub:
Not Epub
Abstract:
Hedgehog (Hh) and Wnt proteins are important signals implicated in several aspects of embryonic development, including the...
Organism or Cell Type:
Xenopus
Citation Extract:
Min TH, Kriebel M, Hou S, Pera EM. The dual regulator Sufu integrates Hedgehog and Wnt signals in the early Xenopus embryo. Dev Biol. 2011 Oct 1;358(1):262-76. doi: 10.1016/j.ydbio.2011.07.035. Epub 2011 Aug 4.

The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

Authors:
Melville DB, Montero-Balaguer M, Levic DS, Bradley K, Smith JR, Hatzopoulos AK, Knapik EW
Citation:
Dis Model Mech. 2011 Nov;4(6):763-76. Epub 2011 Jul 4
Epub:
Not Epub
Abstract:
Craniofacial and skeletal dysmorphologies account for the majority of birth defects. A number of the disease phenotypes have...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Melville DB, Montero-Balaguer M, Levic DS, Bradley K, Smith JR, Hatzopoulos AK, Knapik EW. The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis. Dis Model Mech. 2011 Nov;4(6):763-76. Epub 2011 Jul 4.

The homeobox transcription factor Barx2 regulates chondrogenesis during limb development

Authors:
Meech R, Edelman DB, Jones FS, Makarenkova HP
Citation:
Development. 2005 May;132(9):2135-46. Epub 2005 Mar 30
Epub:
Not Epub
Abstract:
Among the many factors involved in regulation of chondrogenesis, bone morphogenetic proteins (BMPs) and members of the Sox and...
Delivery Method:
Osmotic Delivery System
Organism or Cell Type:
Organ culture: mouse limb bud micromass culture
Citation Extract:
Meech R, Edelman DB, Jones FS, Makarenkova HP. The homeobox transcription factor Barx2 regulates chondrogenesis during limb development. Development. 2005 May;132(9):2135-46. Epub 2005 Mar 30.

The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors

Authors:
Meech R, Makarenkova H, Edelman DB, Jones FS
Citation:
J Biol Chem. 2003 Mar 7;278(10):8269-78.
Epub:
Not Epub
Abstract:
The homeobox protein Barx2 is expressed in both smooth and skeletal muscle and is up-regulated during differentiation of...
Delivery Method:
LipofectAMINE
Organism or Cell Type:
mouse: mesenchymal cells
Citation Extract:
Meech R, Makarenkova H, Edelman DB, Jones FS. The homeodomain protein Barx2 promotes myogenic differentiation and is regulated by myogenic regulatory factors. J Biol Chem. 2003 Mar 7;278(10):8269-78..

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