You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation

Authors:
Mahmood M, Fu S, Cooke J, Wilson SW, Cooper JD, Russell C
Citation:
Brain. 2013;[Epub ahead of print] doi:10.1093/brain/awt043
Epub:
Not Epub
Abstract:
Tripeptidyl peptidase 1 (TPP1) deficiency causes CLN2 disease, late infantile (or classic late infantile neuronal ceroid...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mahmood M, Fu S, Cooke J, Wilson SW, Cooper JD, Russell C. A zebrafish model of CLN2 disease is deficient in tripeptidyl peptidase 1 and displays progressive neurodegeneration accompanied by a reduction in proliferation. Brain. 2013;[Epub ahead of print] doi:10.1093/brain/awt043 .

A {beta}1,4-galactosyltransferase is required for Bmp2-dependent patterning of the dorsoventral axis during zebrafish embryogenesis

Authors:
Machingo QJ, Fritz A, Shur BD
Citation:
Development. 2006 Jun;133(11):2233-41. Epub 2006 May 3.
Epub:
Not Epub
Abstract:
Complex carbohydrates are highly polymorphic macromolecules that are involved in diverse biological processes; however, a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Machingo QJ, Fritz A, Shur BD. A {beta}1,4-galactosyltransferase is required for Bmp2-dependent patterning of the dorsoventral axis during zebrafish embryogenesis. Development. 2006 Jun;133(11):2233-41. Epub 2006 May 3..

A {beta}1,4-galactosyltransferase is required for convergent extension movements in zebrafish

Authors:
Machingo QJ, Fritz A, Shur BD
Citation:
Dev Biol. 2006 Sep 15;297(2):471-82. Epub 2006 May 27
Epub:
Not Epub
Abstract:
Our understanding of how complex carbohydrates function during embryonic development is still very limited, primarily due to...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Machingo QJ, Fritz A, Shur BD. A {beta}1,4-galactosyltransferase is required for convergent extension movements in zebrafish. Dev Biol. 2006 Sep 15;297(2):471-82. Epub 2006 May 27.

Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals

Authors:
Lynch VJ, Tanzer A, Wang Y, Leung FC, Gellersen B, Emera D, Wagner GP
Citation:
Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14928-33. Epub 2008 Sep 22
Epub:
Not Epub
Abstract:
Evolutionary change in gene regulation can result from changes in cis-regulatory elements, leading to differences in the...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: CRL-4003 immortalized human endometrial stromal
Citation Extract:
Lynch VJ, Tanzer A, Wang Y, Leung FC, Gellersen B, Emera D, Wagner GP. Adaptive changes in the transcription factor HoxA-11 are essential for the evolution of pregnancy in mammals. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):14928-33. Epub 2008 Sep 22.

Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells

Authors:
Maître JL, Berthoumieux H, Krens SFG, Salbreux G, Jülicher F, Paluch E, Heisenberg CP
Citation:
Science. 2012;[Epub ahead of print] doi:10.1126/science.1225399
Epub:
Not Epub
Abstract:
Differential cell adhesion and cortex tension are thought to drive cell sorting by controlling cell-cell contact formation....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maître JL, Berthoumieux H, Krens SFG, Salbreux G, Jülicher F, Paluch E, Heisenberg CP. Adhesion Functions in Cell Sorting by Mechanically Coupling the Cortices of Adhering Cells. Science. 2012;[Epub ahead of print] doi:10.1126/science.1225399.

Amyloid-β and APP Deficiencies Cause Severe Cerebrovascular Defects: Important Work for an Old Villain

Authors:
Luna S, Cameron DJ, Ethell DW
Citation:
PLoS ONE. 2013;8(9):e75052. doi:10.1371/journal.pone.0075052
Epub:
Not Epub
Abstract:
Alzheimer’s disease (AD) is marked by neuritic plaques that contain insoluble deposits of amyloid-β (Aβ), yet the physiological...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Luna S, Cameron DJ, Ethell DW. Amyloid-β and APP Deficiencies Cause Severe Cerebrovascular Defects: Important Work for an Old Villain. PLoS ONE. 2013;8(9):e75052. doi:10.1371/journal.pone.0075052.

Analysis of gene function in the zebrafish retina

Authors:
Malicki J, Jo H, Wei X, Hsiung M, Pujic Z
Citation:
Methods. 2002 Dec;28(4):427-438. Review
Epub:
Not Epub
Abstract:
Mutagenesis screens in zebrafish have uncovered several hundred mutant alleles affecting the development of the retina and...
Delivery Method:
not applicable
Organism or Cell Type:
zebrafish
Citation Extract:
Malicki J, Jo H, Wei X, Hsiung M, Pujic Z. Analysis of gene function in the zebrafish retina. Methods. 2002 Dec;28(4):427-438. Review.

Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow

Authors:
Maisonneuve C, Guilleret I, Vick P, Weber T, Andre P, Beyer T, Blum M, Constam DB
Citation:
Development. 2009 Sep;136(17):3019-30
Epub:
Not Epub
Abstract:
Polycystic diseases and left-right (LR) axis malformations are frequently linked to cilia defects. Renal cysts also arise in...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Maisonneuve C, Guilleret I, Vick P, Weber T, Andre P, Beyer T, Blum M, Constam DB. Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow. Development. 2009 Sep;136(17):3019-30.

Carboxypeptidase A6 in Zebrafish Development and Implications for VIth Cranial Nerve Pathfinding

Authors:
Lyons PJ, Ma LH, Baker R, Fricker LD
Citation:
PLoS ONE. 2010;5(9): e12967. doi:10.1371/journal.pone.0012967
Epub:
Not Epub
Abstract:
Carboxypeptidase A6 (CPA6) is an extracellular protease that cleaves carboxy-terminal hydrophobic amino acids and has been...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lyons PJ, Ma LH, Baker R, Fricker LD. Carboxypeptidase A6 in Zebrafish Development and Implications for VIth Cranial Nerve Pathfinding. PLoS ONE. 2010;5(9): e12967. doi:10.1371/journal.pone.0012967.

Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice

Authors:
Malerba A, Sharp PS, Graham IR, Arechavala-Gomeza V, Foster K, Muntoni F, Wells DJ, Dickson G
Citation:
Mol Ther. 2011 Feb;19(2):345-54. Epub 2010 Nov 23.
Epub:
Not Epub
Abstract:
The administration of antisense oligonucleotides (AOs) to skip one or more exons in mutated forms of the DMD gene and so...
Delivery Method:
Injection
Organism or Cell Type:
mice, mdx
Citation Extract:
Malerba A, Sharp PS, Graham IR, Arechavala-Gomeza V, Foster K, Muntoni F, Wells DJ, Dickson G. Chronic Systemic Therapy With Low-dose Morpholino Oligomers Ameliorates the Pathology and Normalizes Locomotor Behavior in mdx Mice. Mol Ther. 2011 Feb;19(2):345-54. Epub 2010 Nov 23..

Pages