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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function
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Citation:
Cancer Gene Ther. 2011 Oct 14. doi: 10.1038/cgt.2011.63. [Epub ahead of print] Epub:
Not Epub Abstract:
CD4+CD25+regulatory T cells (T(reg)) impair anti-tumor and anti-viral immunity. As there are higher T(reg) levels in cancer... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: CD4+CD25+regulatory T cells (Treg) Citation Extract: Morse MA, Hobeika A, Serra D, Aird K, McKinney M, Aldrich A, Clay T, Mourich D, Lyerly HK, Iversen PL, Devi GR. Depleting regulatory T cells with arginine-rich, cell-penetrating, peptide-conjugated morpholino oligomer targeting FOXP3 inhibits regulatory T-cell function. Cancer Gene Ther. 2011 Oct 14. doi: 10.1038/cgt.2011.63. [Epub ahead of print]. |
Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord
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Citation:
PLoS Genet. 2008 Dec;4(12):e1000296. Epub 2008 Dec 5 Epub:
Not Epub Abstract:
Adaptor protein (AP) complexes regulate clathrin-coated vesicle assembly, protein cargo sorting, and vesicular trafficking... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Montpetit A, Côté S, Brustein E, Drouin CA, Lapointe L, Boudreau M, Meloche C, Drouin R, Hudson TJ, Drapeau P, Cossette P. Disruption of AP1S1, Causing a Novel Neurocutaneous Syndrome, Perturbs Development of the Skin and Spinal Cord. PLoS Genet. 2008 Dec;4(12):e1000296. Epub 2008 Dec 5. |
Distinct mechanisms control the timing of differentiation of two myeloid populations in Xenopus ventral blood islands
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Citation:
Dev Growth Differ. 2012;[Epub ahead of print] 10.1111/j.1440-169X.2011.01321.x Epub:
Not Epub Abstract:
Previous study has suggested that distinct populations of myeloid cells exist in the anterior ventral blood islands (aVBI) and... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Mitsugu M, Kyogo K, Yoko M, Junichi H, Sayaka K, Hiroyuki S, Yumi I. Distinct mechanisms control the timing of differentiation of two myeloid populations in Xenopus ventral blood islands. Dev Growth Differ. 2012;[Epub ahead of print] 10.1111/j.1440-169X.2011.01321.x. |
Diversin regulates heart formation and gastrulation movements in development.
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Citation:
Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15900-5. Epub 2006 Oct 10. Epub:
Not Epub Abstract:
Canonical and noncanonical Wnt signaling regulate crucial events in the development of vertebrates and invertebrates. In this... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Moeller H, Jenny A, Schaeffer HJ, Schwarz-Romond T, Mlodzik M, Hammerschmidt M, Birchmeier W.. Diversin regulates heart formation and gastrulation movements in development.. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15900-5. Epub 2006 Oct 10.. |
Ectodermal FGFs induce perinodular inhibition of limb chondrogenesis in vitro and in vivo via FGF receptor 2
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Citation:
Dev Biol. 2002 Sep 15;249(2):270-82 Epub:
Not Epub Abstract:
The formation of cartilage elements in the developing vertebrate limb, where they serve as primordia for the appendicular... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: Moftah MZ, Downie SA, Bronstein NB, Mezentseva N, Pu J, Maher PA, Newman SA. Ectodermal FGFs induce perinodular inhibition of limb chondrogenesis in vitro and in vivo via FGF receptor 2. Dev Biol. 2002 Sep 15;249(2):270-82. |
Effect of Vascular Cadherin Knockdown on Zebrafish Vasculature during Development
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Citation:
PLoS One. 2010 Jan 20;5(1):e8807 Epub:
Not Epub Abstract:
BACKGROUND: Vascular endothelial cadherin (VE-cad) is essential for endothelial barrier integrity and vascular sprouting.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mitchell IC, Brown TS, Terada LS, Amatruda JF, Nwariaku FE. Effect of Vascular Cadherin Knockdown on Zebrafish Vasculature during Development. PLoS One. 2010 Jan 20;5(1):e8807. |
Enhanced exon skipping in the 4CV dystrophic mouse model of muscular dystrophy through refined oligomer design
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Citation:
Neuromusc Disord. 2012;22(9):858 Epub:
Not Epub Abstract:
Antisense oligomer (AO) induced dual dystrophin exon skipping was studied in the B6Ros.Cg-Dmdmdx-4Cv/J (4CV) mouse, an... Delivery Method:
Injection Organism or Cell Type:
Mouse, mdx-4Cv Citation Extract: Mitrpant C, Fletcher S, Pinniger G, Johnsen R, Kole R, Wilton SD. Enhanced exon skipping in the 4CV dystrophic mouse model of muscular dystrophy through refined oligomer design. Neuromusc Disord. 2012;22(9):858. |
Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development
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Citation:
Biol Open. 2013 Apr 10;2(5):515-24. doi: 10.1242/bio.20134226. Print 2013 May 15. Epub:
Not Epub Abstract:
Fibroblast growth factor (Fgf) signaling plays important roles in various developmental processes including brain development.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Miyake A, Itoh N. Fgf22 regulated by Fgf3/Fgf8 signaling is required for zebrafish midbrain development. Biol Open. 2013 Apr 10;2(5):515-24. doi: 10.1242/bio.20134226. Print 2013 May 15.. |
Flamingo, a cadherin-type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis
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Citation:
Int J Dev Biol. 2003 May;47(4):245-52 Epub:
Not Epub Abstract:
The Flamingo gene encodes a seven-pass transmembrane receptor of the cadherin super family and is one of a growing number of... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Morgan R, El-Kadi AM, Theokli C. Flamingo, a cadherin-type receptor involved in the Drosophila planar polarity pathway, can block signaling via the canonical wnt pathway in Xenopus laevis. Int J Dev Biol. 2003 May;47(4):245-52. |
FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, is directly regulated by Hoxb4 in the notochord
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Citation:
Dev Biol. 2004 Jan 1;265(1):105-12 Epub:
Not Epub Abstract:
The Hox genes are a family of homeodomain-containing transcription factors that confer positional identity during development.... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus notochords Citation Extract: Morgan R, Nalliah A, Morsi El-Kadi AS. FLASH, a component of the FAS-CAPSASE8 apoptotic pathway, is directly regulated by Hoxb4 in the notochord. Dev Biol. 2004 Jan 1;265(1):105-12. |