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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Induced dystrophin exon skipping in human muscle explants

Authors:
McClorey G, Fall AM, Moulton HM, Iversen PL, Rasko JE, Ryan M, Fletcher S, Wilton SD
Citation:
Neuromuscul Disord. 2006 Oct;16(9-10):583-90. Epub 2006 Aug 21
Epub:
Not Epub
Abstract:
Antisense oligonucleotide (AO) manipulation of pre-mRNA splicing of the dystrophin gene is showing promise in overcoming...
Delivery Method:
peptide-coupled
Organism or Cell Type:
muscle explants, mouse and human
Citation Extract:
McClorey G, Fall AM, Moulton HM, Iversen PL, Rasko JE, Ryan M, Fletcher S, Wilton SD. Induced dystrophin exon skipping in human muscle explants. Neuromuscul Disord. 2006 Oct;16(9-10):583-90. Epub 2006 Aug 21.

Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome

Authors:
Maurya AK, Tan H, Souren M, Wang X, Wittbrodt J, Ingham PW
Citation:
Development. 2011 Feb;138(4):755-65. doi: 10.1242/dev.062521. Erratum in: Development. 2012 May;139(10):1885
Epub:
Not Epub
Abstract:
Different levels and timing of Hedgehog (Hh) signalling activity have been proposed to specify three distinct cell types in the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Maurya AK, Tan H, Souren M, Wang X, Wittbrodt J, Ingham PW. Integration of Hedgehog and BMP signalling by the engrailed2a gene in the zebrafish myotome. Development. 2011 Feb;138(4):755-65. doi: 10.1242/dev.062521. Erratum in: Development. 2012 May;139(10):1885.

Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue

Authors:
Matsuda M, Chitnis AB
Citation:
Development. 2009 Jan;136(2):197-206. Epub 2008 Dec 4
Epub:
Not Epub
Abstract:
Mind bomb1 (Mib1)-mediated endocytosis of the Notch ligand DeltaD is essential for activation of Notch in a neighboring cell....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matsuda M, Chitnis AB. Interaction with Notch determines endocytosis of specific Delta ligands in zebrafish neural tissue. Development. 2009 Jan;136(2):197-206. Epub 2008 Dec 4.

JunB-CBF{beta} signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure

Authors:
Meder B, Just S, Vogel B, Rudloff J, Gärtner L, Dahme T, Huttner I, Zankl A, Katus HA, Rottbauer W
Citation:
J Cell Sci. 2010 Jul 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In muscle cells, a complex network of Z-disc proteins allows proper reception, transduction and transmission of mechanical and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Meder B, Just S, Vogel B, Rudloff J, Gärtner L, Dahme T, Huttner I, Zankl A, Katus HA, Rottbauer W. JunB-CBF{beta} signaling is essential to maintain sarcomeric Z-disc structure and when defective leads to heart failure. J Cell Sci. 2010 Jul 6. [Epub ahead of print].

Knockdown of duplicated zebrafish hoxb1 genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention

Authors:
McClintock JM, Kheirbek MA, Prince VE
Citation:
Development. 2002 May 15;129(10):2339-2354
Epub:
Not Epub
Abstract:
We have used a morpholino-based knockdown approach to investigate the functions of a pair of zebrafish Hox gene duplicates,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McClintock JM, Kheirbek MA, Prince VE. Knockdown of duplicated zebrafish hoxb1 genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention. Development. 2002 May 15;129(10):2339-2354.

Knockdown of the complete Hox paralogous group 1 leads to dramatic hindbrain and neural crest defects

Authors:
McNulty CL, Peres JN, Bardine N, van den Akker WM, Durston AJ
Citation:
Development. 2005 Jun;132(12):2861-71
Epub:
Not Epub
Abstract:
The Hox paralogous group 1 (PG1) genes are the first and initially most anterior Hox genes expressed in the embryo. In Xenopus...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
McNulty CL, Peres JN, Bardine N, van den Akker WM, Durston AJ. Knockdown of the complete Hox paralogous group 1 leads to dramatic hindbrain and neural crest defects. Development. 2005 Jun;132(12):2861-71.

Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding

Authors:
McWhorter ML, Monani UR, Burghes AH, Beattie CE
Citation:
J Cell Biol. 2003 Sep 1;162(5):919-32
Epub:
Not Epub
Abstract:
Spinal muscular atrophy (SMA) is an autosomal recessive disorder characterized by a loss of alpha motoneurons in the spinal...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McWhorter ML, Monani UR, Burghes AH, Beattie CE. Knockdown of the survival motor neuron (Smn) protein in zebrafish causes defects in motor axon outgrowth and pathfinding. J Cell Biol. 2003 Sep 1;162(5):919-32.

Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium

Authors:
McGraw HF, Drerup CM, Culbertson MD, Linbo T, Raible DW, Nechiporuk AV
Citation:
Development. 2011 Sep;138(18):3921-30
Epub:
Not Epub
Abstract:
The zebrafish posterior lateral line (pLL) is a sensory system that comprises clusters of mechanosensory organs called...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McGraw HF, Drerup CM, Culbertson MD, Linbo T, Raible DW, Nechiporuk AV. Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium. Development. 2011 Sep;138(18):3921-30.

Live imaging of chronic inflammation caused by mutation of zebrafish Hai1

Authors:
Mathias JR, Dodd ME, Walters KB, Rhodes J, Kanki JP, Look AT, Huttenlocher A
Citation:
J Cell Sci. 2007 Oct 1;120(Pt 19):3372-83
Epub:
Not Epub
Abstract:
The hallmark of chronic inflammation is the infiltration and persistence of leukocytes within inflamed tissue. Here, we...
Organism or Cell Type:
zebrafish
Citation Extract:
Mathias JR, Dodd ME, Walters KB, Rhodes J, Kanki JP, Look AT, Huttenlocher A. Live imaging of chronic inflammation caused by mutation of zebrafish Hai1. J Cell Sci. 2007 Oct 1;120(Pt 19):3372-83.

Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish

Authors:
McMahon C, Gestri G, Wilson SW, Link BA
Citation:
Dev Biol. 2009 Jun 2. [Epub ahead of print]
Epub:
Not Epub
Abstract:
To gain insight into the mechanisms of Lmx1b function during ocular morphogenesis, we have studied the roles of lmx1b.1 and...
Organism or Cell Type:
zebrafish
Citation Extract:
McMahon C, Gestri G, Wilson SW, Link BA. Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish. Dev Biol. 2009 Jun 2. [Epub ahead of print].

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