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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
There are 12371 scientific papers returned from the database with the search filters currently being used below.
Arginine-rich cell-penetrating peptides with uncharged antisense oligomers
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Citation:
Drug Discov Today. 2004 Oct 15;9(20):870 Epub:
Not Epub Abstract:
No abstract available. Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Moulton HM, Moulton JD. Arginine-rich cell-penetrating peptides with uncharged antisense oligomers. Drug Discov Today. 2004 Oct 15;9(20):870. |
Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivo
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Citation:
Mol Cell Neurosci. 2010 Jun;44(2):118-28. Epub 2010 Mar 16 Epub:
Not Epub Abstract:
We have investigated the role of Vav2, a reported Rac1/Cdc42 GEF, on the development of Xenopus spinal neurons in vitro and in... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Moon MS, Gomez TM. Balanced Vav2 GEF activity regulates neurite outgrowth and branching in vitro and in vivo. Mol Cell Neurosci. 2010 Jun;44(2):118-28. Epub 2010 Mar 16. |
beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification
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Citation:
Gastroenterology. 2003 Jan;124(1):202-216 Epub:
Not Epub Abstract:
BACKGROUND & AIMS: Wnt/beta-catenin pathway activation occurs during liver growth in hepatoblastomas, hepatocellular... Delivery Method:
oligo bathing Organism or Cell Type:
organ culture: mouse liver explants Citation Extract: Monga SP, Monga HK, Tan X, Mule K, Pediaditakis P, Michalopoulos GK. beta-catenin antisense studies in embryonic liver cultures: Role in proliferation, apoptosis, and lineage specification. Gastroenterology. 2003 Jan;124(1):202-216. |
Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway.
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Citation:
EMBO J. 2005 Apr 6;24(7):1397-405. Epub 2005 Mar 17. Epub:
Not Epub Abstract:
The BMP4 signaling pathway plays key roles during early embryonic development and for maintenance of adult homeostasis. In the... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Moreno M, Munoz R, Aroca F, Labarca M, Brandan E, Larrain J. Biglycan is a new extracellular component of the Chordin-BMP4 signaling pathway.. EMBO J. 2005 Apr 6;24(7):1397-405. Epub 2005 Mar 17.. |
BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish
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Citation:
J Mol Cell Cardiol. 2007 Sep;43(3):243-53. Epub 2007 May 18 Epub:
Not Epub Abstract:
For the proper development of vertebrate embryos as well as for survival of the adult organism, it is essential to form a... Organism or Cell Type:
zebrafish Citation Extract: Moser M, Yu Q, Bode C, Xiong JW, Patterson C. BMPER is a conserved regulator of hematopoietic and vascular development in zebrafish. J Mol Cell Cardiol. 2007 Sep;43(3):243-53. Epub 2007 May 18. |
Brain induction in ascidian embryos is dependent on juxtaposition of FGF9/16/20-producing and -receiving cells
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Citation:
Dev Genes Evol. 2007 Mar;217(3):177-88. Epub 2007 Jan 11 Epub:
Not Epub Abstract:
Coordinated regulation of inductive events, both spatially and temporally, during animal development ensures that tissues are... Delivery Method:
Microinjection Organism or Cell Type:
Halocynthia roretzi (ascidian) Citation Extract: Miyazaki Y, Nishida H, Kumano G. Brain induction in ascidian embryos is dependent on juxtaposition of FGF9/16/20-producing and -receiving cells. Dev Genes Evol. 2007 Mar;217(3):177-88. Epub 2007 Jan 11. |
By-passing the nonsense mutation in the 4(CV) mouse model of muscular dystrophy by induced exon skipping
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Citation:
J Gene Med. 2008 Nov 12. [Epub ahead of print] Epub:
Not Epub Abstract:
BACKGROUND: Duchenne muscular dystrophy (DMD), a severe neuromuscular disorder, is caused by protein-truncating mutations in... Delivery Method:
Injection Organism or Cell Type:
Mouse, mdx-4Cv Citation Extract: Mitrpant C, Fletcher S, Iversen PL, Wilton SD. By-passing the nonsense mutation in the 4(CV) mouse model of muscular dystrophy by induced exon skipping. J Gene Med. 2008 Nov 12. [Epub ahead of print]. |
Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo
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Citation:
Biochem Soc Trans. 2007 Aug;35(Pt 4):826-8 Epub:
Not Epub Abstract:
The cellular uptake of PMOs (phosphorodiamidate morpholino oligomers) can be enhanced by their conjugation to arginine-rich... Delivery Method:
peptide-coupled Organism or Cell Type:
mice (mdx), dog myoblasts Citation Extract: Moulton HM, Fletcher S, Neuman BW, McClorey G, Stein DA, Abes S, Wilton SD, Buchmeier MJ, Lebleu B, Iversen PL. Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. Biochem Soc Trans. 2007 Aug;35(Pt 4):826-8. |
Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers
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Citation:
Methods Mol Biol. 2012;867:407-14 Epub:
Not Epub Abstract:
Exon-skipping efficacy of phosphorodiamidate morpholino oligomers (Morpholinos) has been demonstrated in a proof-of-concept... Delivery Method:
peptide-coupled Organism or Cell Type:
mice, mdx and utrophin/dystrophin dKO Citation Extract: Moulton HM. Cell-penetrating peptides enhance systemic delivery of antisense morpholino oligomers. Methods Mol Biol. 2012;867:407-14. |
Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides
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Citation:
Bioconjug Chem. 2004 Mar-Apr;15(2):290-9 Epub:
Not Epub Abstract:
Although the sequence specificity, biostability, and low toxicity of PMO (phosphorodiamidate morpholino oligomers) make them... Delivery Method:
peptide-coupled Organism or Cell Type:
cell culture: HeLa pLuc705 and NIH-3T3 cells Citation Extract: Moulton HM, Nelson MH, Hatlevig SA, Reddy MT, Iversen PL. Cellular uptake of antisense morpholino oligomers conjugated to arginine-rich peptides. Bioconjug Chem. 2004 Mar-Apr;15(2):290-9. |