You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing

Authors:
Marshall NB, Oda SK, London CA, Moulton HM, Iversen PL, Kerkvliet NI, Mourich DV
Citation:
J Immunol Methods. 2007 Aug 31;325(1-2):114-26. Epub 2007 Jul 27
Epub:
Not Epub
Abstract:
Phosphorodiamidate morpholino oligomers (PMO) are synthetic antisense molecules that interfere with translation, pre-mRNA...
Delivery Method:
peptide-coupled
Organism or Cell Type:
cell culture: mouse primary leukocytes
Citation Extract:
Marshall NB, Oda SK, London CA, Moulton HM, Iversen PL, Kerkvliet NI, Mourich DV. Arginine-rich cell-penetrating peptides facilitate delivery of antisense oligomers into murine leukocytes and alter pre-mRNA splicing. J Immunol Methods. 2007 Aug 31;325(1-2):114-26. Epub 2007 Jul 27.

Ataxia, Dementia, and Hypogonadotropism Caused by Disordered Ubiquitination

Authors:
Margolin DH, Kousi M, Chan Y-M, Lim ET, Schmahmann JD, Hadjivassiliou M, Hall JE, Adam I, Dwyer A, Plummer L, Aldrin SV, O’Rourke J, Kirby A, Lage K, Milunsky A, Milunsky JM, Chan J, Hedley-Whyte ET, Daly MJ, Katsanis N, Seminara SB
Citation:
N Engl J Med. 2013;[Epub ahead of print] doi:10.1056/NEJMoa1215993
Epub:
Not Epub
Abstract:
Background The combination of ataxia and hypogonadism was first described more than a century ago, but its genetic basis has...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Margolin DH, Kousi M, Chan Y-M, Lim ET, Schmahmann JD, Hadjivassiliou M, Hall JE, Adam I, Dwyer A, Plummer L, Aldrin SV, O’Rourke J, Kirby A, Lage K, Milunsky A, Milunsky JM, Chan J, Hedley-Whyte ET, Daly MJ, Katsanis N, Seminara SB. Ataxia, Dementia, and Hypogonadotropism Caused by Disordered Ubiquitination. N Engl J Med. 2013;[Epub ahead of print] doi:10.1056/NEJMoa1215993.

ATM-Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response

Authors:
Martin NT, Nakamura K, Davies R, Nahas SA, Brown C, Tunuguntla R, Gatti RA, Hu H
Citation:
PLoS Genet. 2013;9(5):e1003505. doi:10.1371/journal.pgen.1003505
Epub:
Not Epub
Abstract:
ATM plays a critical role in cellular responses to DNA double-strand breaks (DSBs). We describe a new ATM–mediated DSB–induced...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
cell culture: lymphoblastoid cell lines RS7 & RS73 and MCF7 cells
Citation Extract:
Martin NT, Nakamura K, Davies R, Nahas SA, Brown C, Tunuguntla R, Gatti RA, Hu H. ATM-Dependent MiR-335 Targets CtIP and Modulates the DNA Damage Response. PLoS Genet. 2013;9(5):e1003505. doi:10.1371/journal.pgen.1003505.

BMP inhibition initiates neural induction via FGF signaling and Zic genes

Authors:
Marchal L, Luxardi G, Thomé V, Kodjabachian L
Citation:
Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17437-42. Epub 2009 Sep 28
Epub:
Not Epub
Abstract:
Neural induction is the process that initiates nervous system development in vertebrates. Two distinct models have been put...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Marchal L, Luxardi G, Thomé V, Kodjabachian L. BMP inhibition initiates neural induction via FGF signaling and Zic genes. Proc Natl Acad Sci U S A. 2009 Oct 13;106(41):17437-42. Epub 2009 Sep 28.

cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification

Authors:
Marek KW, Kurtz LM, Spitzer NC
Citation:
Nat Neurosci. 2010 Aug;13(8):944-50. Epub 2010 Jun 27
Epub:
Not Epub
Abstract:
Neuronal differentiation is accomplished through cascades of intrinsic genetic factors initiated in neuronal progenitors by...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Marek KW, Kurtz LM, Spitzer NC. cJun integrates calcium activity and tlx3 expression to regulate neurotransmitter specification. Nat Neurosci. 2010 Aug;13(8):944-50. Epub 2010 Jun 27.

Comparative genomic and expression analysis of the conserved NTPDase gene family in Xenopus

Authors:
Massé K, Eason R, Bhamra S, Dale N, Jones EA
Citation:
Genomics. 2006 Mar;87(3):366-81. Epub 2005 Dec 27
Epub:
Not Epub
Abstract:
The purines, ATP and adenosine, are important signaling molecules in the nervous system. ATP is sequentially degraded to...
Organism or Cell Type:
Xenopus
Citation Extract:
Massé K, Eason R, Bhamra S, Dale N, Jones EA. Comparative genomic and expression analysis of the conserved NTPDase gene family in Xenopus. Genomics. 2006 Mar;87(3):366-81. Epub 2005 Dec 27.

Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway

Authors:
Marcet B, Chevalier B, Luxardi G, Coraux C, Zaragosi LE, Cibois M, Robbe-Sermesant K, Jolly T, Cardinaud B, Moreilhon C, Giovannini-Chami L, Nawrocki-Raby B, Birembaut P, Waldmann R, Kodjabachian L, Barbry P
Citation:
Nat Cell Biol. 2011 May 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Multiciliated cells lining the surface of some vertebrate epithelia are essential for various physiological processes, such as...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Marcet B, Chevalier B, Luxardi G, Coraux C, Zaragosi LE, Cibois M, Robbe-Sermesant K, Jolly T, Cardinaud B, Moreilhon C, Giovannini-Chami L, Nawrocki-Raby B, Birembaut P, Waldmann R, Kodjabachian L, Barbry P. Control of vertebrate multiciliogenesis by miR-449 through direct repression of the Delta/Notch pathway. Nat Cell Biol. 2011 May 22. [Epub ahead of print].

Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality

Authors:
Marques SR, Yelon D
Citation:
Dev Biol. 2009 Apr 15;328(2):472-82. Epub 2009 Feb 20
Epub:
Not Epub
Abstract:
The function of an organ relies upon the proper relative proportions of its individual operational components. For example,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Marques SR, Yelon D. Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality. Dev Biol. 2009 Apr 15;328(2):472-82. Epub 2009 Feb 20.

Dynamic Lkb1-TORC1 signaling as a possible mechanism for regulating the endoderm-intestine transition

Authors:
Marshall KE, Tomasini AJ, Makky K, N Kumar S, Mayer AN
Citation:
Dev Dyn. 2010 Oct 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The intestinal epithelium arises from undifferentiated endoderm via a developmental program known as the endoderm-intestine...
Organism or Cell Type:
zebrafish
Citation Extract:
Marshall KE, Tomasini AJ, Makky K, N Kumar S, Mayer AN. Dynamic Lkb1-TORC1 signaling as a possible mechanism for regulating the endoderm-intestine transition. Dev Dyn. 2010 Oct 5. [Epub ahead of print].

Exome Sequencing and Functional Validation in Zebrafish Identify GTDC2 Mutations as a Cause of Walker-Warburg Syndrome

Authors:
Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, Salih MA, Clark R, Moroni I, Mora M, Beggs AH, Gabriel SB, Walsh CA
Citation:
AJHG. 2012;91(3):547-7 doi:10.1016/j.ajhg.2012.07.009
Epub:
Not Epub
Abstract:
Whole-exome sequencing (WES), which analyzes the coding sequence of most annotated genes in the human genome, is an ideal...
Organism or Cell Type:
zebrafish
Citation Extract:
Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, Salih MA, Clark R, Moroni I, Mora M, Beggs AH, Gabriel SB, Walsh CA. Exome Sequencing and Functional Validation in Zebrafish Identify GTDC2 Mutations as a Cause of Walker-Warburg Syndrome. AJHG. 2012;91(3):547-7 doi:10.1016/j.ajhg.2012.07.009 .

Pages