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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization
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Citation:
Circulation. 2009 Aug 18;120(7):553-9. Epub 2009 Aug 3 Epub:
Not Epub Abstract:
BACKGROUND: Cardiac repolarization, the process by which cardiomyocytes return to their resting potential after each beat, is a... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Milan DJ, Kim AM, Winterfield JR, Jones IL, Pfeufer A, Sanna S, Arking DE, Amsterdam AH, Sabeh KM, Mably JD, Rosenbaum DS, Peterson RT, Chakravarti A, Kääb S, Roden DM, MacRae CA. Drug-sensitized zebrafish screen identifies multiple genes, including GINS3, as regulators of myocardial repolarization. Circulation. 2009 Aug 18;120(7):553-9. Epub 2009 Aug 3. |
Drugs that induce repolarization abnormalities cause bradycardia in zebrafish
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Citation:
Circulation. 2003 Mar 18;107(10):1355-8. Epub:
Not Epub Abstract:
BACKGROUND: Drug-induced QT prolongation and torsades de pointes remain significant and often unpredictable clinical problems.... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Milan DJ, Peterson TA, Ruskin JN, Peterson RT, MacRae CA. Drugs that induce repolarization abnormalities cause bradycardia in zebrafish. Circulation. 2003 Mar 18;107(10):1355-8.. |
Eteplirsen for the treatment of duchenne muscular dystrophy
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Citation:
Ann Neurol. 2013;74(5):637-647 doi:10.1002/ana.23982 Epub:
Not Epub Abstract:
Objective In prior open-label studies, eteplirsen, a phosphorodiamidate morpholino oligomer (PMO), enabled dystrophin... Delivery Method:
iv infusion Organism or Cell Type:
human Citation Extract: Mendell J, Rodino-Klapac LR, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Kota J, Malik V, Shontz K, Walker CM, Flanigan KM, Kean JR, Allen HD, Shilling C, Melia KR, Sazani P, Saoud JB, Kaye EM, The Eteplirsen Study Group. Eteplirsen for the treatment of duchenne muscular dystrophy. Ann Neurol. 2013;74(5):637-647 doi:10.1002/ana.23982. |
Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration
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Citation:
Mol Biol Cell. 2009 Jan;20(1):78-89. Epub 2008 Oct 22. Erratum in: Mol Biol Cell. 2010 May;21(9):1643 Epub:
Not Epub Abstract:
Cell adhesion molecules such as cadherins alternate their expression throughout cranial neural crest (CNC) development, yet our... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: McCusker C, Cousin H, Neuner R, Alfandari D. Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration. Mol Biol Cell. 2009 Jan;20(1):78-89. Epub 2008 Oct 22. Erratum in: Mol Biol Cell. 2010 May;21(9):1643. |
FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration
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Citation:
J Cell Biol. 2003 Apr 28;161(2):393-402 Epub:
Not Epub Abstract:
Fibroblast migration depends, in part, on activation of FAK and cellular interactions with tenascin-C (TN-C). Consistent with... Delivery Method:
Special Delivery Organism or Cell Type:
Cell culture: mouse FAK-wild-type fibroblasts from E8.5 mice Citation Extract: McKean DM, Sisbarro L, Ilic D, Kaplan-Alburquerque N, Nemenoff R, Weiser-Evans M, Kern MJ, Jones PL. FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration. J Cell Biol. 2003 Apr 28;161(2):393-402. |
ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish
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Citation:
Mol Genet Metab. 2010 Oct 1. [Epub ahead of print] Epub:
Not Epub Abstract:
The adrenal cortex and pancreatic islets have endocrine functions, producing steroid-based hormones and insulin, respectively.... Organism or Cell Type:
zebrafish Citation Extract: Mazilu JK, Powers JW, Lin S, McCabe ER. ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish. Mol Genet Metab. 2010 Oct 1. [Epub ahead of print]. |
Fibrillin-2b regulates endocardial morphogenesis in zebrafish
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Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.015 Epub:
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Scotch tape (sco) is a zebrafish cardiac mutant initially proposed to exhibit a reduced amount of cardiac jelly, the... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Mellman K, Huisken J, Dinsmore C, Hoppe C, Stainier DY. Fibrillin-2b regulates endocardial morphogenesis in zebrafish. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.015. |
Fishing for gene function--endocrine modelling in the zebrafish
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Citation:
J Endocrinol. 2006 Jun;189(3):425-39 Epub:
Not Epub Abstract:
The use of zebrafish (Danio rerio) in scientific research is growing rapidly. It initially became popular as a model of... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: McGonnell IM, Fowkes RC. Fishing for gene function--endocrine modelling in the zebrafish. J Endocrinol. 2006 Jun;189(3):425-39. |
FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula
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Citation:
Development. 2007 Jan 17; [Epub ahead of print] Epub:
Not Epub Abstract:
The segregation of the vertebrate embryo into three primary germ layers is one of the earliest developmental decisions. In... Organism or Cell Type:
Xenopus Citation Extract: Mir A, Kofron M, Zorn AM, Bajzer M, Haque M, Heasman J, Wylie CC. FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula. Development. 2007 Jan 17; [Epub ahead of print]. |
Friend of GATA (FOG) Interacts with the Nucleosome Remodeling and Deacetylase Complex (NuRD) to Support Primitive Erythropoiesis in Xenopus laevis
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Citation:
PLoS ONE. 2012;7(1):e29882. doi:10.1371/journal.pone.0029882 Epub:
Not Epub Abstract:
Friend of GATA (FOG) plays many diverse roles in adult and embryonic hematopoiesis, however the mechanisms by which it... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Mimoto MS, Christian JL. Friend of GATA (FOG) Interacts with the Nucleosome Remodeling and Deacetylase Complex (NuRD) to Support Primitive Erythropoiesis in Xenopus laevis. PLoS ONE. 2012;7(1):e29882. doi:10.1371/journal.pone.0029882. |