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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The polarity protein scrib is essential for directed endothelial cell migration

Authors:
Michaelis UR, Chavakis E, Kruse C, Jungblut B, Kaluza D, Wandzioch K, Manavski Y, Heide H, Santoni MJ, Potente M, Eble JA, Borg JP, Brandes RP
Citation:
Circ Res. 2013 Mar 15;112(6):924-34. doi: 10.1161/CIRCRESAHA.112.300592. Epub 2013 Jan 29
Epub:
Not Epub
Abstract:
Rationale: Polarity proteins are involved in the apico-basal orientation of epithelial cells, but relatively little is known...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Michaelis UR, Chavakis E, Kruse C, Jungblut B, Kaluza D, Wandzioch K, Manavski Y, Heide H, Santoni MJ, Potente M, Eble JA, Borg JP, Brandes RP. The polarity protein scrib is essential for directed endothelial cell migration. Circ Res. 2013 Mar 15;112(6):924-34. doi: 10.1161/CIRCRESAHA.112.300592. Epub 2013 Jan 29.

The SMN binding protein gemin2 is not involved in motor axon outgrowth

Authors:
McWhorter ML, Boon KL, Horan ES, Burghes AH, Beattie CE
Citation:
Dev Neurobiol. 2008 Feb 1;68(2):182-94.
Epub:
Not Epub
Abstract:
A paramount question in spinal muscular atrophy (SMA) research is why reduced levels of SMN, a ubiquitously expressed protein,...
Organism or Cell Type:
zebrafish
Citation Extract:
McWhorter ML, Boon KL, Horan ES, Burghes AH, Beattie CE. The SMN binding protein gemin2 is not involved in motor axon outgrowth. Dev Neurobiol. 2008 Feb 1;68(2):182-94..

The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny

Authors:
McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon E, Lengerke C, Zon LI, Collins JJ, Daley GQ
Citation:
Cell stem cell. 2012;11(5);701-14. doi:10.1016/j.stem.2012.07.018
Epub:
Not Epub
Abstract:
Transcriptome analysis of adult hematopoietic stem cells (HSCs) and their progeny has revealed mechanisms of blood...
Organism or Cell Type:
zebrafish
Citation Extract:
McKinney-Freeman S, Cahan P, Li H, Lacadie SA, Huang HT, Curran M, Loewer S, Naveiras O, Kathrein KL, Konantz M, Langdon E, Lengerke C, Zon LI, Collins JJ, Daley GQ. The Transcriptional Landscape of Hematopoietic Stem Cell Ontogeny. Cell stem cell. 2012;11(5);701-14. doi:10.1016/j.stem.2012.07.018 .

The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development

Authors:
Meani N, Pezzimenti F, Deflorian G, Mione M, Alcalay M
Citation:
PLoS ONE. 2009;4(1):e4273. Epub 2009 Jan 26
Epub:
Not Epub
Abstract:
PRDM genes are a family of transcriptional regulators that modulate cellular processes such as differentiation, cell growth and...
Organism or Cell Type:
zebrafish
Citation Extract:
Meani N, Pezzimenti F, Deflorian G, Mione M, Alcalay M. The tumor suppressor PRDM5 regulates Wnt signaling at early stages of zebrafish development. PLoS ONE. 2009;4(1):e4273. Epub 2009 Jan 26.

The zebrafish dyrk1b gene is important for endoderm formation

Authors:
Mazmanian G, Kovshilovsky M, Yen D, Mohanty A, Mohanty S, Nee A, Nissen RM
Citation:
Genesis. 2009. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Nodal-signaling is required for specification of mesoderm, endoderm, establishing left-right asymmetry, and craniofacial...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mazmanian G, Kovshilovsky M, Yen D, Mohanty A, Mohanty S, Nee A, Nissen RM. The zebrafish dyrk1b gene is important for endoderm formation. Genesis. 2009. [Epub ahead of print].

The zebrafish embryo as a dynamic model of anoxia tolerance

Authors:
Mendelsohn BA, Kassebaum BL, Gitlin JD
Citation:
Dev Dyn. 2008 Jul;237(7):1780-8
Epub:
Not Epub
Abstract:
Developing organisms depend upon a delicate balance in the supply and demand of energy to adapt to variable oxygen availability...
Organism or Cell Type:
zebrafish
Citation Extract:
Mendelsohn BA, Kassebaum BL, Gitlin JD. The zebrafish embryo as a dynamic model of anoxia tolerance. Dev Dyn. 2008 Jul;237(7):1780-8.

The zebrafish onecut gene hnf-6 functions in an evolutionarily conserved genetic pathway that regulates vertebrate biliary development

Authors:
Matthews RP, Lorent K, Russo P, Pack M
Citation:
Dev Biol. 2004 Oct 15;274(2):245-59
Epub:
Not Epub
Abstract:
Targeted disruption of the onecut transcription factor, hnf-6, alters mammalian biliary system development. We have identified...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Matthews RP, Lorent K, Russo P, Pack M. The zebrafish onecut gene hnf-6 functions in an evolutionarily conserved genetic pathway that regulates vertebrate biliary development. Dev Biol. 2004 Oct 15;274(2):245-59.

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

Authors:
Miller GW, Ulatowski L, Labut EM, Lebold KM, Manor D, Atkinson J, Barton CL, Tanguay RL, Traber MG
Citation:
PLoS ONE. 2012;7(10):e47402. doi:10.1371/journal.pone.0047402
Epub:
Not Epub
Abstract:
The hepatic α-tocopherol transfer protein (TTP) is required for optimal α-tocopherol bioavailability in humans; mutations in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Miller GW, Ulatowski L, Labut EM, Lebold KM, Manor D, Atkinson J, Barton CL, Tanguay RL, Traber MG. The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis. PLoS ONE. 2012;7(10):e47402. doi:10.1371/journal.pone.0047402.

The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism

Authors:
Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ
Citation:
Dev Cell. 2012 Jan 17;22(1):197-210. doi: 10.1016/j.devcel.2011.10.028. Epub 2011 Dec 15
Epub:
Not Epub
Abstract:
Mutations in Pkd1, encoding polycystin-1 (PC1), cause autosomal-dominant polycystic kidney disease (ADPKD). We show that the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Merrick D, Chapin H, Baggs JE, Yu Z, Somlo S, Sun Z, Hogenesch JB, Caplan MJ. The γ-secretase cleavage product of polycystin-1 regulates TCF and CHOP-mediated transcriptional activation through a p300-dependent mechanism. Dev Cell. 2012 Jan 17;22(1):197-210. doi: 10.1016/j.devcel.2011.10.028. Epub 2011 Dec 15.

TNF{alpha}-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase

Authors:
Matthews RP, Lorent K, Mañoral-Mobias R, Huang Y, Gong W, Murray IV, Blair IA, Pack M
Citation:
Development. 2009 Mar;136(5):865-75
Epub:
Not Epub
Abstract:
Hepatic steatosis and liver degeneration are prominent features of the zebrafish ducttrip (dtp) mutant phenotype. Positional...
Organism or Cell Type:
zebrafish
Citation Extract:
Matthews RP, Lorent K, Mañoral-Mobias R, Huang Y, Gong W, Murray IV, Blair IA, Pack M. TNF{alpha}-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish s-adenosylhomocysteine hydrolase. Development. 2009 Mar;136(5):865-75.

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