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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Eteplirsen for the treatment of duchenne muscular dystrophy

Authors:
Mendell J, Rodino-Klapac LR, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Kota J, Malik V, Shontz K, Walker CM, Flanigan KM, Kean JR, Allen HD, Shilling C, Melia KR, Sazani P, Saoud JB, Kaye EM, The Eteplirsen Study Group
Citation:
Ann Neurol. 2013;74(5):637-647 doi:10.1002/ana.23982
Epub:
Not Epub
Abstract:
Objective In prior open-label studies, eteplirsen, a phosphorodiamidate morpholino oligomer (PMO), enabled dystrophin...
Delivery Method:
iv infusion
Organism or Cell Type:
human
Citation Extract:
Mendell J, Rodino-Klapac LR, Sahenk Z, Roush K, Bird L, Lowes LP, Alfano L, Gomez AM, Lewis S, Kota J, Malik V, Shontz K, Walker CM, Flanigan KM, Kean JR, Allen HD, Shilling C, Melia KR, Sazani P, Saoud JB, Kaye EM, The Eteplirsen Study Group. Eteplirsen for the treatment of duchenne muscular dystrophy. Ann Neurol. 2013;74(5):637-647 doi:10.1002/ana.23982.

Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration

Authors:
McCusker C, Cousin H, Neuner R, Alfandari D
Citation:
Mol Biol Cell. 2009 Jan;20(1):78-89. Epub 2008 Oct 22. Erratum in: Mol Biol Cell. 2010 May;21(9):1643
Epub:
Not Epub
Abstract:
Cell adhesion molecules such as cadherins alternate their expression throughout cranial neural crest (CNC) development, yet our...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
McCusker C, Cousin H, Neuner R, Alfandari D. Extracellular cleavage of cadherin-11 by ADAM metalloproteases is essential for Xenopus cranial neural crest cell migration. Mol Biol Cell. 2009 Jan;20(1):78-89. Epub 2008 Oct 22. Erratum in: Mol Biol Cell. 2010 May;21(9):1643.

FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration

Authors:
McKean DM, Sisbarro L, Ilic D, Kaplan-Alburquerque N, Nemenoff R, Weiser-Evans M, Kern MJ, Jones PL
Citation:
J Cell Biol. 2003 Apr 28;161(2):393-402
Epub:
Not Epub
Abstract:
Fibroblast migration depends, in part, on activation of FAK and cellular interactions with tenascin-C (TN-C). Consistent with...
Delivery Method:
Special Delivery
Organism or Cell Type:
Cell culture: mouse FAK-wild-type fibroblasts from E8.5 mice
Citation Extract:
McKean DM, Sisbarro L, Ilic D, Kaplan-Alburquerque N, Nemenoff R, Weiser-Evans M, Kern MJ, Jones PL. FAK induces expression of Prx1 to promote tenascin-C-dependent fibroblast migration. J Cell Biol. 2003 Apr 28;161(2):393-402.

ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish

Authors:
Mazilu JK, Powers JW, Lin S, McCabe ER
Citation:
Mol Genet Metab. 2010 Oct 1. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The adrenal cortex and pancreatic islets have endocrine functions, producing steroid-based hormones and insulin, respectively....
Organism or Cell Type:
zebrafish
Citation Extract:
Mazilu JK, Powers JW, Lin S, McCabe ER. ff1b, the SF1 ortholog, is important for pancreatic islet cell development in zebrafish. Mol Genet Metab. 2010 Oct 1. [Epub ahead of print].

Fibrillin-2b regulates endocardial morphogenesis in zebrafish

Authors:
Mellman K, Huisken J, Dinsmore C, Hoppe C, Stainier DY
Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.015
Epub:
Not Epub
Abstract:
Scotch tape (sco) is a zebrafish cardiac mutant initially proposed to exhibit a reduced amount of cardiac jelly, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mellman K, Huisken J, Dinsmore C, Hoppe C, Stainier DY. Fibrillin-2b regulates endocardial morphogenesis in zebrafish. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.015.

Fishing for gene function--endocrine modelling in the zebrafish

Authors:
McGonnell IM, Fowkes RC
Citation:
J Endocrinol. 2006 Jun;189(3):425-39
Epub:
Not Epub
Abstract:
The use of zebrafish (Danio rerio) in scientific research is growing rapidly. It initially became popular as a model of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
McGonnell IM, Fowkes RC. Fishing for gene function--endocrine modelling in the zebrafish. J Endocrinol. 2006 Jun;189(3):425-39.

FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula

Authors:
Mir A, Kofron M, Zorn AM, Bajzer M, Haque M, Heasman J, Wylie CC
Citation:
Development. 2007 Jan 17; [Epub ahead of print]
Epub:
Not Epub
Abstract:
The segregation of the vertebrate embryo into three primary germ layers is one of the earliest developmental decisions. In...
Organism or Cell Type:
Xenopus
Citation Extract:
Mir A, Kofron M, Zorn AM, Bajzer M, Haque M, Heasman J, Wylie CC. FoxI1e activates ectoderm formation and controls cell position in the Xenopus blastula. Development. 2007 Jan 17; [Epub ahead of print].

Friend of GATA (FOG) Interacts with the Nucleosome Remodeling and Deacetylase Complex (NuRD) to Support Primitive Erythropoiesis in Xenopus laevis

Authors:
Mimoto MS, Christian JL
Citation:
PLoS ONE. 2012;7(1):e29882. doi:10.1371/journal.pone.0029882
Epub:
Not Epub
Abstract:
Friend of GATA (FOG) plays many diverse roles in adult and embryonic hematopoiesis, however the mechanisms by which it...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Mimoto MS, Christian JL. Friend of GATA (FOG) Interacts with the Nucleosome Remodeling and Deacetylase Complex (NuRD) to Support Primitive Erythropoiesis in Xenopus laevis. PLoS ONE. 2012;7(1):e29882. doi:10.1371/journal.pone.0029882.

Functional specificity of the Xenopus T-domain protein brachyury is conferred by its ability to interact with smad1

Authors:
Messenger NJ, Kabitschke C, Andrews R, Grimmer D, Miguel RN, Blundell TL, Smith JC, Wardle FC
Citation:
Dev Cell. 2005 Apr;8(4):599-610
Epub:
Not Epub
Abstract:
Members of the T-box gene family play important and diverse roles in development and disease. Here, we study the functional...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Messenger NJ, Kabitschke C, Andrews R, Grimmer D, Miguel RN, Blundell TL, Smith JC, Wardle FC. Functional specificity of the Xenopus T-domain protein brachyury is conferred by its ability to interact with smad1. Dev Cell. 2005 Apr;8(4):599-610.

Geminin Deficiency Causes a Chk1-dependent G2 Arrest in Xenopus

Authors:
McGarry TJ
Citation:
Mol Biol Cell. 2002 Oct 1; 13(10): 3662-3671
Epub:
Not Epub
Abstract:
Geminin is an unstable inhibitor of DNA replication that gets destroyed at the metaphase/anaphase transition. The biological...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
McGarry TJ. Geminin Deficiency Causes a Chk1-dependent G2 Arrest in Xenopus. Mol Biol Cell. 2002 Oct 1; 13(10): 3662-3671.

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