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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12175 scientific papers returned from the database with the search filters currently being used below.
There are 12175 scientific papers returned from the database with the search filters currently being used below.
Impairment of Preimplantation Porcine Embryo Development by Histone Demethylase KDM5B Knockdown Through Disturbance of Bivalent H3K4me3-H3K27me3 Modifications
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Citation:
Biol Reprod. 2015 Jan 21. pii: biolreprod.114.122762. [Epub ahead of print] Epub:
Yes Abstract:
KDM5B (JARID1B/PLU1) is a H3K4me2/3 histone demethylase, which is implicated in cancer development and proliferation, and is... Delivery Method:
oocyte microinjection Organism or Cell Type:
Sus scrofa domesticus (pig) Citation Extract: Huang J, Zhang H, Wang X, Dobbs KB, Yao J, Qin G, Whitworth K, Walters EM, Prather RS, Zhao J. Impairment of Preimplantation Porcine Embryo Development by Histone Demethylase KDM5B Knockdown Through Disturbance of Bivalent H3K4me3-H3K27me3 Modifications. Biol Reprod. 2015 Jan 21. pii: biolreprod.114.122762. [Epub ahead of print]. |
Abnormal Cartilage Development and Altered N-Glycosylation in Tmem165-Deficient Zebrafish Mirrors the Phenotypes Associated with TMEM165-CDG
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Citation:
Glycobiology. 2015 Jan 21. pii: cwv009. [Epub ahead of print] Epub:
Yes Abstract:
The Congenital Disorders of Glycosylation (CDG), a group of inherited diseases characterized by defective glycosylation,... Organism or Cell Type:
zebrafish Citation Extract: Bammens R, Mehta N, Race V, Foulquier F, Jaeken J, Tiemeyer M, Steet R, Matthijs G, Flanagan-Steet H. Abnormal Cartilage Development and Altered N-Glycosylation in Tmem165-Deficient Zebrafish Mirrors the Phenotypes Associated with TMEM165-CDG. Glycobiology. 2015 Jan 21. pii: cwv009. [Epub ahead of print]. |
β-catenin-dependent transcription is central to Bmp-mediated formation of venous vessels
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Citation:
Development. 2015;142:497-509. doi:10.1242/dev.115576 Epub:
Not Epub Abstract:
β-catenin regulates the transcription of genes involved in diverse biological processes, including embryogenesis, tissue... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Kashiwada T, Fukuhara S, Terai K, Tanaka T, Wakayama Y, Ando K, Nakajima H, Fukui H, Yuge S, Saito Y, Gemma A, Mochizuki N. β-catenin-dependent transcription is central to Bmp-mediated formation of venous vessels. Development. 2015;142:497-509. doi:10.1242/dev.115576. |
mab21-l3 regulates cell fate specification of multiciliate cells and ionocytes
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Citation:
Nat Commun. 2015 Jan 19;6:6017. doi: 10.1038/ncomms7017 Epub:
Not Epub Abstract:
Cell fate specifications of multiciliate cells (MCCs) and ionocytes are commonly suppressed by the Notch pathway in developing... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Takahashi C, Kusakabe M, Suzuki T, Miyatake K, Nishida E. mab21-l3 regulates cell fate specification of multiciliate cells and ionocytes. Nat Commun. 2015 Jan 19;6:6017. doi: 10.1038/ncomms7017. |
G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons
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Citation:
Nature. 2015 Jan 19. doi: 10.1038/nature14051. [Epub ahead of print] Epub:
Yes Abstract:
The regulated release of anorexigenic α-melanocyte stimulating hormone (α-MSH) and orexigenic Agouti-related protein (AgRP)... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ghamari-Langroudi M, Digby GJ, Sebag JA, Millhauser GL, Palomino R, Matthews R, Gillyard T, Panaro BL, Tough IR, Cox HM, Denton JS, Cone RD. G-protein-independent coupling of MC4R to Kir7.1 in hypothalamic neurons. Nature. 2015 Jan 19. doi: 10.1038/nature14051. [Epub ahead of print]. |
PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis
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Citation:
Nat Comm. 2015;6:5953. doi:10.1038/ncomms6953 Epub:
Not Epub Abstract:
How metabolism regulators play roles during early development remains elusive. Here we show that PFKFB4 (6-phosphofructo-2-... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Pegoraro C, Figueiredo AL, Maczkowiak F, Pouponnot C, Eychène A, Monsoro-Burq AH. PFKFB4 controls embryonic patterning via Akt signalling independently of glycolysis. Nat Comm. 2015;6:5953. doi:10.1038/ncomms6953. |
Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish
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Citation:
Mol Cell Biol. 2015 Jan 20. pii: MCB.01181-14. [Epub ahead of print] Epub:
Yes Abstract:
Nucleoporin p62 (Nup62) localizes in the central channel of nuclear pore complexes (NPCs) and regulates nuclear pore... Organism or Cell Type:
zebrafish Citation Extract: Yang X, Gu Q, Lin L, Li S, Zhong S, Li Q, Cui Z. Nucleoporin 62-like protein activates canonical Wnt signaling through facilitating the nuclear import of β-catenin in zebrafish. Mol Cell Biol. 2015 Jan 20. pii: MCB.01181-14. [Epub ahead of print]. |
Tgfβ1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway
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Citation:
J Mol Cell Biol. 2015 Jan 20. pii: mjv004. [Epub ahead of print] Epub:
Yes Abstract:
The zebrafish sensory posterior lateral line (pLL) has become an attractive model for studying collective cell migration and... Organism or Cell Type:
zebrafish Citation Extract: Xing C, Gong B, Xue Y, Han Y, Wang Y, Meng A, Jia S. Tgfβ1a regulates zebrafish posterior lateral line formation via Smad5 mediated pathway. J Mol Cell Biol. 2015 Jan 20. pii: mjv004. [Epub ahead of print]. |
Involvement of TLR7 and TLR8 in Conceptus Development and Establishment of Pregnancy in Sheep
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Citation:
Reproduction. 2015 Apr;149(4):305-16. doi: 10.1530/REP-14-0537. Epub 2015 Jan 19. Epub:
Not Epub Abstract:
Toll-like receptors (TLRs) belong to the innate immune system and regulate inflammatory events that impact mammalian... Organism or Cell Type:
Ovis aries (sheep) Citation Extract: Ruiz-González I, Minten M, Wang X, Dunlap K, Bazer FW. Involvement of TLR7 and TLR8 in Conceptus Development and Establishment of Pregnancy in Sheep. Reproduction. 2015 Apr;149(4):305-16. doi: 10.1530/REP-14-0537. Epub 2015 Jan 19.. |
Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides
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Citation:
Nucleic Acid Ther. 2015 Jan 16. [Epub ahead of print] Epub:
Yes Abstract:
Oligonucleotide analogs have provided novel therapeutics targeting various disorders. However, their poor cellular uptake... Delivery Method:
peptide nanoparticle Organism or Cell Type:
cell culture: U2OS cells, murine H2K mdx myotubes, human SMA type 1 fibroblasts Citation Extract: Järver P, Zaghloul EM, Arzumanov AA, Saleh AF, McClorey G, Hammond SM, Hällbrink M, Langel Ü, Smith CI, Wood MJ, Gait MJ, Andaloussi SE. Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides. Nucleic Acid Ther. 2015 Jan 16. [Epub ahead of print]. |