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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio

Authors:
Ivanova AS, Shandarin IN, Ermakova GV, Minin AA, Tereshina MB, Zaraisky AG
Citation:
Sci Rep. 2015 Jan 29;5:8123. doi: 10.1038/srep08123
Epub:
Not Epub
Abstract:
Agr family includes three groups of genes, Ag1, Agr2 and Agr3, which encode the thioredoxin domain-containing secreted proteins...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
zebrafish
Citation Extract:
Ivanova AS, Shandarin IN, Ermakova GV, Minin AA, Tereshina MB, Zaraisky AG. The secreted factor Ag1 missing in higher vertebrates regulates fins regeneration in Danio rerio. Sci Rep. 2015 Jan 29;5:8123. doi: 10.1038/srep08123.

Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos

Authors:
McClelland KS, Wainwright EN, Bowles J, Koopman P
Citation:
PLoS One. 2015 Jan 28;10(1):e0114932. doi: 10.1371/journal.pone.0114932. eCollection 2015
Epub:
Not Epub
Abstract:
Traditional gene targeting methods in mice are complex and time consuming, especially when conditional deletion methods are...
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mice
Citation Extract:
McClelland KS, Wainwright EN, Bowles J, Koopman P. Rapid screening of gene function by systemic delivery of morpholino oligonucleotides to live mouse embryos. PLoS One. 2015 Jan 28;10(1):e0114932. doi: 10.1371/journal.pone.0114932. eCollection 2015.

Correction: Manipulation of Developing Juvenile Structures in Purple Sea Urchins (Strongylocentrotus purpuratus) by Morpholino Injection into Late Stage Larvae

Authors:
The PLOS ONE Staff
Citation:
PLoS One. 2015 Jan 27;10(1):e0117679. doi: 10.1371/journal.pone.0117679. eCollection 2015
Epub:
Not Epub
Abstract:
There is an error in Fig. 5, "Developing spine structures in S. purpuratus." Please see the corrected Fig. 5 here.
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin)
Citation Extract:
The PLOS ONE Staff. Correction: Manipulation of Developing Juvenile Structures in Purple Sea Urchins (Strongylocentrotus purpuratus) by Morpholino Injection into Late Stage Larvae. PLoS One. 2015 Jan 27;10(1):e0117679. doi: 10.1371/journal.pone.0117679. eCollection 2015.

A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity

Authors:
Dou S, Virostko J, Greiner DL, Powers AC, Liu G
Citation:
Nucleosides Nucleotides Nucleic Acids. 2015 Feb;34(2):69-78. doi: 10.1080/15257770.2014.958236
Epub:
Not Epub
Abstract:
Synthetic DNA analogues with improved stability are widely used in life science. The 3'and/or 5' equivalent...
Citation Extract:
Dou S, Virostko J, Greiner DL, Powers AC, Liu G. A Feasible Approach to Evaluate the Relative Reactivity of NHS-Ester Activated Group with Primary Amine-Derivatized DNA Analogue and Non-Derivatized Impurity. Nucleosides Nucleotides Nucleic Acids. 2015 Feb;34(2):69-78. doi: 10.1080/15257770.2014.958236.

Zebrafish Rnf111 is encoded by multiple transcripts and is required for epiboly progression and prechordal plate development

Authors:
Bessarab DA, Mathavan S, Jones CM, Ray Dunn N
Citation:
Differentiation. 2015 Jan 22. pii: S0301-4681(14)00099-1. doi: 10.1016/j.diff.2014.12.004. [Epub ahead of print]
Epub:
Yes
Abstract:
Arkadia (also known as RING finger 111) encodes a nuclear E3 ubiquitin ligase that targets intracellular effectors and...
Organism or Cell Type:
zebrafish
Citation Extract:
Bessarab DA, Mathavan S, Jones CM, Ray Dunn N. Zebrafish Rnf111 is encoded by multiple transcripts and is required for epiboly progression and prechordal plate development. Differentiation. 2015 Jan 22. pii: S0301-4681(14)00099-1. doi: 10.1016/j.diff.2014.12.004. [Epub ahead of print].

Non-manifesting AHI1 truncations indicate localized loss-of-function tolerance in a severe Mendelian disease gene

Authors:
Elsayed SM, Phillips JB, Heller R, Thoenes M, Elsobky E, Nürnberg G, Nürnberg P, Seland S, Ebermann I, Altmüller J, Thiele H, Toliat M, Körber F, Hu X, Wu YD, Zaki MS, Abdel-Salam G, Gleeson J, Boltshauser E, Westerfield M, Bolz HJ
Citation:
Hum Mol Genet. 2015 Jan 23. pii: ddv022. [Epub ahead of print]
Epub:
Yes
Abstract:
Determination of variant pathogenicity represents a major challenge in the era of high-throughput sequencing. Erroneous...
Organism or Cell Type:
zebrafish
Citation Extract:
Elsayed SM, Phillips JB, Heller R, Thoenes M, Elsobky E, Nürnberg G, Nürnberg P, Seland S, Ebermann I, Altmüller J, Thiele H, Toliat M, Körber F, Hu X, Wu YD, Zaki MS, Abdel-Salam G, Gleeson J, Boltshauser E, Westerfield M, Bolz HJ. Non-manifesting AHI1 truncations indicate localized loss-of-function tolerance in a severe Mendelian disease gene. Hum Mol Genet. 2015 Jan 23. pii: ddv022. [Epub ahead of print].

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus

Authors:
Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PL, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E
Citation:
Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031
Epub:
Not Epub
Abstract:
Gene-regulatory network analysis is a powerful approach to elucidate the molecular processes and pathways underlying complex...
Organism or Cell Type:
zebrafish
Citation Extract:
Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PL, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E. Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus. Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031.

Genetic Heterogeneity of Pseudoxanthoma Elasticum: The Chinese Signature Profile of ABCC6 and ENPP1 Mutations

Authors:
Jin L, Jiang Q, Wu Z, Shao C, Zhou Y, Yang L, Uitto J, Wang G
Citation:
J Invest Dermatol. 2015 Jan 23. doi: 10.1038/jid.2015.10. [Epub ahead of print]
Epub:
Yes
Abstract:
Pseudoxanthoma elasticum (PXE), an autosomal recessive disorder characterized by ectopic mineralization, is caused by mutations...
Organism or Cell Type:
zebrafish
Citation Extract:
Jin L, Jiang Q, Wu Z, Shao C, Zhou Y, Yang L, Uitto J, Wang G. Genetic Heterogeneity of Pseudoxanthoma Elasticum: The Chinese Signature Profile of ABCC6 and ENPP1 Mutations. J Invest Dermatol. 2015 Jan 23. doi: 10.1038/jid.2015.10. [Epub ahead of print].

Impairment of Preimplantation Porcine Embryo Development by Histone Demethylase KDM5B Knockdown Through Disturbance of Bivalent H3K4me3-H3K27me3 Modifications

Authors:
Huang J, Zhang H, Wang X, Dobbs KB, Yao J, Qin G, Whitworth K, Walters EM, Prather RS, Zhao J
Citation:
Biol Reprod. 2015 Jan 21. pii: biolreprod.114.122762. [Epub ahead of print]
Epub:
Yes
Abstract:
KDM5B (JARID1B/PLU1) is a H3K4me2/3 histone demethylase, which is implicated in cancer development and proliferation, and is...
Delivery Method:
oocyte microinjection
Organism or Cell Type:
Sus scrofa domesticus (pig)
Citation Extract:
Huang J, Zhang H, Wang X, Dobbs KB, Yao J, Qin G, Whitworth K, Walters EM, Prather RS, Zhao J. Impairment of Preimplantation Porcine Embryo Development by Histone Demethylase KDM5B Knockdown Through Disturbance of Bivalent H3K4me3-H3K27me3 Modifications. Biol Reprod. 2015 Jan 21. pii: biolreprod.114.122762. [Epub ahead of print].

Abnormal Cartilage Development and Altered N-Glycosylation in Tmem165-Deficient Zebrafish Mirrors the Phenotypes Associated with TMEM165-CDG

Authors:
Bammens R, Mehta N, Race V, Foulquier F, Jaeken J, Tiemeyer M, Steet R, Matthijs G, Flanagan-Steet H
Citation:
Glycobiology. 2015 Jan 21. pii: cwv009. [Epub ahead of print]
Epub:
Yes
Abstract:
The Congenital Disorders of Glycosylation (CDG), a group of inherited diseases characterized by defective glycosylation,...
Organism or Cell Type:
zebrafish
Citation Extract:
Bammens R, Mehta N, Race V, Foulquier F, Jaeken J, Tiemeyer M, Steet R, Matthijs G, Flanagan-Steet H. Abnormal Cartilage Development and Altered N-Glycosylation in Tmem165-Deficient Zebrafish Mirrors the Phenotypes Associated with TMEM165-CDG. Glycobiology. 2015 Jan 21. pii: cwv009. [Epub ahead of print].

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