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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A

Authors:
Ingold E, vom Berg-Maurer CM, Burckhardt CJ, Lehnherr A, Rieder P, Keller PJ, Stelzer EH, Greber UF, Neuhauss SCF, Gesemann M
Citation:
Bio Open. 2015;[Epub] doi:10.1242/bio.20148482
Epub:
Not Epub
Abstract:
The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors....
Link:
http://bio.biologists.org/content/early/2015/01/04/bio.20148482.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ingold E, vom Berg-Maurer CM, Burckhardt CJ, Lehnherr A, Rieder P, Keller PJ, Stelzer EH, Greber UF, Neuhauss SCF, Gesemann M. Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A. Bio Open. 2015;[Epub] doi:10.1242/bio.20148482 .

Fgf-Signaling-Dependent Sox9a and Atoh1a Regulate Otic Neural Development in Zebrafish

Authors:
Wang J, Wu Y, Zhao F, Wu Y, Dong W, Zhao J, Zhu Z, Liu D
Citation:
J Neurosci. 2015;35(1):234-244. doi:10.1523/JNEUROSCI.3353-14.2015
Epub:
Not Epub
Abstract:
Fibroblast growth factors (Fgfs) play important roles in developmental processes of the inner ear, including the ontogeny of...
Link:
http://www.jneurosci.org/content/35/1/234.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wang J, Wu Y, Zhao F, Wu Y, Dong W, Zhao J, Zhu Z, Liu D. Fgf-Signaling-Dependent Sox9a and Atoh1a Regulate Otic Neural Development in Zebrafish. J Neurosci. 2015;35(1):234-244. doi:10.1523/JNEUROSCI.3353-14.2015.

Myoinhibitory peptide regulates feeding in the marine annelid Platynereis

Authors:
Williams EA, Conzelmann M, Jékely G
Citation:
Front Zool. 2015;[Epub ahead of print] doi:10.1186/s12983-014-0093-6
Epub:
Yes
Abstract:
Background: During larval settlement and metamorphosis, marine invertebrates undergo changes in habitat, morphology, behavior...
Link:
http://www.frontiersinzoology.com/content/12/1/1/abstract
Delivery Method:
microinjection
Organism or Cell Type:
Platyneris dumerilii (annelid)
Citation Extract:
Williams EA, Conzelmann M, Jékely G. Myoinhibitory peptide regulates feeding in the marine annelid Platynereis. Front Zool. 2015;[Epub ahead of print] doi:10.1186/s12983-014-0093-6.

The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes

Authors:
Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P, Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O’ Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E, Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M, Doxsey S, Jackson A, Stupka E, Winey M, Beales PL
Citation:
J Med Genet. 2015 Mar;52(3):147-56. doi: 10.1136/jmedgenet-2014-102691. Epub 2015 Jan 6
Epub:
Not Epub
Abstract:
Background: Mutations in microtubule-regulating genes are associated with disorders of neuronal migration and microcephaly....
Link:
http://jmg.bmj.com/content/early/2015/01/06/jmedgenet-2014-102691.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Waters AM, Asfahani R, Carroll P, Bicknell L, Lescai F, Bright A, Chanudet E, Brooks A, Christou-Savina S, Osman G, Walsh P, Bacchelli C, Chapgier A, Vernay B, Bader DM, Deshpande C, O’ Sullivan M, Ocaka L, Stanescu H, Stewart HS, Hildebrandt F, Otto E, Johnson CA, Szymanska K, Katsanis N, Davis E, Kleta R, Hubank M, Doxsey S, Jackson A, Stupka E, Winey M, Beales PL. The kinetochore protein, CENPF, is mutated in human ciliopathy and microcephaly phenotypes. J Med Genet. 2015 Mar;52(3):147-56. doi: 10.1136/jmedgenet-2014-102691. Epub 2015 Jan 6.

Mutations in RAD21 Disrupt Regulation of APOB in Patients with Chronic Intestinal Pseudo-obstruction

Authors:
Bonora E, Bianco F, Cordeddu L, Bamshad M, Francescatto L, Dowless D, Stanghellini V, Cogliandro RF, Lindberg G, Mungan Z, Cefle K, Ozcelik T, Palanduz S, Ozturk S, Gedikbasi A, Gori A, Pippucci T, Graziano C, Volta U, Caio G, Barbara G, D'Amato M, Seri M, Katsanis N, Romeo G, De Giorgio R
Citation:
Gastroenterology. 2014;[Epub ahead of print] doi:10.1053/j.gastro.2014.12.034
Epub:
Yes
Abstract:
Background & Aims: Chronic intestinal pseudo-obstruction (CIPO) is characterized by severe intestinal dysmotility that...
Link:
http://www.gastrojournal.org/article/S0016-5085%2815%2900010-4/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonora E, Bianco F, Cordeddu L, Bamshad M, Francescatto L, Dowless D, Stanghellini V, Cogliandro RF, Lindberg G, Mungan Z, Cefle K, Ozcelik T, Palanduz S, Ozturk S, Gedikbasi A, Gori A, Pippucci T, Graziano C, Volta U, Caio G, Barbara G, D'Amato M, Seri M, Katsanis N, Romeo G, De Giorgio R. Mutations in RAD21 Disrupt Regulation of APOB in Patients with Chronic Intestinal Pseudo-obstruction. Gastroenterology. 2014;[Epub ahead of print] doi:10.1053/j.gastro.2014.12.034.

Sox4 regulates choroid fissure closure by limiting hedgehog signaling during ocular morphogenesis

Authors:
Wen W, Pillai-Kastoori L, Wilson SG, Morris AC
Citation:
Dev Biol. 2014 Dec 31. pii: S0012-1606(14)00667-8. doi: 10.1016/j.ydbio.2014.12.026. [Epub ahead of print]
Epub:
Yes
Abstract:
SoxC transcription factors play critical roles in many developmental processes, including neurogenesis, cardiac formation, and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160614006678
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wen W, Pillai-Kastoori L, Wilson SG, Morris AC. Sox4 regulates choroid fissure closure by limiting hedgehog signaling during ocular morphogenesis. Dev Biol. 2014 Dec 31. pii: S0012-1606(14)00667-8. doi: 10.1016/j.ydbio.2014.12.026. [Epub ahead of print].

Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages

Authors:
Nagendran M, Arora P, Gori P, Mulay A, Ray S, Jacob T, Sonawane M
Citation:
Development. 2015;142:320-330. doi:10.1242/dev.118703
Epub:
Not Epub
Abstract:
Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. The...
Link:
http://dev.biologists.org/content/142/2/320
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Nagendran M, Arora P, Gori P, Mulay A, Ray S, Jacob T, Sonawane M. Canonical Wnt signalling regulates epithelial patterning by modulating levels of laminins in zebrafish appendages. Development. 2015;142:320-330. doi:10.1242/dev.118703 .

DCDC2 Mutations Cause a Renal-Hepatic Ciliopathy by Disrupting Wnt Signaling

Authors:
Schueler M, Braun DA, Chandrasekar G, Gee HY, Klasson TD, Halbritter J, Bieder A, Porath JD, Airik R, Zhou W, LoTurco JL, Che A, Otto EA, Böckenhauer D, Sebire NJ, Honzik T, Harris PC, Koon SJ, Gunay-Aygun M, Saunier S, Zerres K, Bruechle NO, Drenth JPH, Pelletier L, Tapia-Páez I, Lifton RP, Giles RH, Kere J, Hildebrandt F
Citation:
Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.12.002
Epub:
Yes
Abstract:
Nephronophthisis-related ciliopathies (NPHP-RC) are recessive diseases characterized by renal dysplasia or degeneration. We...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2814%2900508-4#
Organism or Cell Type:
zebrafish
Citation Extract:
Schueler M, Braun DA, Chandrasekar G, Gee HY, Klasson TD, Halbritter J, Bieder A, Porath JD, Airik R, Zhou W, LoTurco JL, Che A, Otto EA, Böckenhauer D, Sebire NJ, Honzik T, Harris PC, Koon SJ, Gunay-Aygun M, Saunier S, Zerres K, Bruechle NO, Drenth JPH, Pelletier L, Tapia-Páez I, Lifton RP, Giles RH, Kere J, Hildebrandt F. DCDC2 Mutations Cause a Renal-Hepatic Ciliopathy by Disrupting Wnt Signaling. Am J Hum Genet. 2014;[Epub ahead of print] doi:10.1016/j.ajhg.2014.12.002.

FMRP regulates neurogenesis in vivo in Xenopus laevis tadpoles

Authors:
Faulkner RL, Wishard TJ, Thompson CK, Liu H-H, Cline HT
Citation:
eNeuro. 2014;[Epub ahead of print] doi:10.1523/ENEURO.0055-14.2014
Epub:
Yes
Abstract:
Fragile X Syndrome (FXS) is the leading known monogenic form of autism and the most common form of inherited intellectual...
Link:
http://eneuro.org/content/eneuro/early/2014/12/31/ENEURO.0055-14.2014.full.pdf
Delivery Method:
brain ventricle injection then electroporation
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Faulkner RL, Wishard TJ, Thompson CK, Liu H-H, Cline HT. FMRP regulates neurogenesis in vivo in Xenopus laevis tadpoles. eNeuro. 2014;[Epub ahead of print] doi:10.1523/ENEURO.0055-14.2014.

MAT2A Mutations Predispose Individuals to Thoracic Aortic Aneurysms

Authors:
Guo D-c, Gong L, Regalado ES, Santos-Cortez RL, Zhao R, Cai B, Veeraraghavan S, Prakash SK, Johnson RJ, Muilenburg A, Willing M, Jondeau G, Boileau C, Pannu H, Moran R, Debacker J, GenTAC Investigators, National Heart, Lung, and Blood Institute Go Exome Sequencing Project, Montalcino Aortic Consortium, Bamshad MJ, Shendure J, Nickerson DA, Leal SM, Raman CS, Swindell EC, Milewicz DM
Citation:
Am J Hum Genet. 2015;[Epub ahead of print] doi:10.1016/j.ajhg.2014.11.015
Epub:
Yes
Abstract:
Up to 20% of individuals who have thoracic aortic aneurysms or acute aortic dissections but who do not have syndromic features...
Link:
http://www.cell.com/ajhg/abstract/S0002-9297%2814%2900502-3
Organism or Cell Type:
zebrafish
Citation Extract:
Guo D-c, Gong L, Regalado ES, Santos-Cortez RL, Zhao R, Cai B, Veeraraghavan S, Prakash SK, Johnson RJ, Muilenburg A, Willing M, Jondeau G, Boileau C, Pannu H, Moran R, Debacker J, GenTAC Investigators, National Heart, Lung, and Blood Institute Go Exome Sequencing Project, Montalcino Aortic Consortium, Bamshad MJ, Shendure J, Nickerson DA, Leal SM, Raman CS, Swindell EC, Milewicz DM. MAT2A Mutations Predispose Individuals to Thoracic Aortic Aneurysms. Am J Hum Genet. 2015;[Epub ahead of print] doi:10.1016/j.ajhg.2014.11.015.

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