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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Peroxisome Proliferator Activator Receptor Gamma (PPARG) Regulates Conceptus Elongation in Sheep

Authors:
Brooks KE, Burns GW, Spencer TE
Citation:
Biol Reprod. 2014 Dec 17. pii: biolreprod.114.123877. [Epub ahead of print]
Epub:
Yes
Abstract:
The ovine blastocyst hatches from the zona pellucida by Day 8 and develops into an ovoid or tubular conceptus (embryo and...
Delivery Method:
Endo-Porter (EP) in culture, intrauterine infusion with EP
Organism or Cell Type:
Ovis aries (sheep)
Citation Extract:
Brooks KE, Burns GW, Spencer TE. Peroxisome Proliferator Activator Receptor Gamma (PPARG) Regulates Conceptus Elongation in Sheep. Biol Reprod. 2014 Dec 17. pii: biolreprod.114.123877. [Epub ahead of print].

Biological Roles of Interferon Tau (IFNT) and Type I IFN Receptors in Elongation of the Ovine Conceptus

Authors:
Brooks K, Spencer TE
Citation:
Biol Reprod. 2014 Dec 10. pii: biolreprod.114.124156. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Interferon tau (IFNT) is produced by the elongating conceptus in ruminants and is the maternal recognition of pregnancy signal...
Delivery Method:
Endo-Porter (EP) in culture, intrauterine injection with EP, intrauterine infusion with EP
Organism or Cell Type:
Ovis aries (sheep)
Citation Extract:
Brooks K, Spencer TE. Biological Roles of Interferon Tau (IFNT) and Type I IFN Receptors in Elongation of the Ovine Conceptus. Biol Reprod. 2014 Dec 10. pii: biolreprod.114.124156. [Epub ahead of print].

The role of the Pax1/9 gene in the early development of amphioxus pharyngeal gill slits

Authors:
Liu X, Li G, Liu X, Wang YQ
Citation:
J Exp Zool B Mol Dev Evol. 2015 Jan;324(1):30-40. doi: 10.1002/jez.b.22596
Epub:
Not Epub
Abstract:
The pharynx is a major characteristic of chordates. Compared with vertebrates, amphioxus has an advantage for the study of...
Organism or Cell Type:
amphioxus
Citation Extract:
Liu X, Li G, Liu X, Wang YQ. The role of the Pax1/9 gene in the early development of amphioxus pharyngeal gill slits. J Exp Zool B Mol Dev Evol. 2015 Jan;324(1):30-40. doi: 10.1002/jez.b.22596.

Aryl hydrocarbon receptor 2 mediates the toxicity of Paclobutrazol on the digestive system of zebrafish embryos

Authors:
Wang WD, Chen GT, Hsu HJ, Wu CY
Citation:
Aquat Toxicol. 2014 Dec 3;159C:13-22. doi: 10.1016/j.aquatox.2014.11.018. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Paclobutrazol (PBZ), a trazole-containing fungicide and plant growth retardant, has been widely used for over 30 years to...
Organism or Cell Type:
zebrafish
Citation Extract:
Wang WD, Chen GT, Hsu HJ, Wu CY. Aryl hydrocarbon receptor 2 mediates the toxicity of Paclobutrazol on the digestive system of zebrafish embryos. Aquat Toxicol. 2014 Dec 3;159C:13-22. doi: 10.1016/j.aquatox.2014.11.018. [Epub ahead of print].

Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish

Authors:
Kok FO, Shin M, Ni C-W, Gupta A, Grosse AS, van Impel A, Kirchmaier BC, Peterson-Maduro J, Kourkoulis G, Male I, DeSantis DF, Sheppard-Tindell S, Ebarasi L, Betsholtz C, Schulte-Merker S, Wolfe SA, Lawson ND
Citation:
Dev Cell. 2015 Jan 12;32(1):97-108. doi: 10.1016/j.devcel.2014.11.018. Epub 2014 Dec 18
Epub:
Yes
Abstract:
The widespread availability of programmable site-specific nucleases now enables targeted gene disruption in the zebrafish. In...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kok FO, Shin M, Ni C-W, Gupta A, Grosse AS, van Impel A, Kirchmaier BC, Peterson-Maduro J, Kourkoulis G, Male I, DeSantis DF, Sheppard-Tindell S, Ebarasi L, Betsholtz C, Schulte-Merker S, Wolfe SA, Lawson ND. Reverse Genetic Screening Reveals Poor Correlation between Morpholino-Induced and Mutant Phenotypes in Zebrafish. Dev Cell. 2015 Jan 12;32(1):97-108. doi: 10.1016/j.devcel.2014.11.018. Epub 2014 Dec 18.

Chondroitin 4-O-sulfotransferases are required for cell adhesion and morphogenesis in the Ciona intestinalis embryo

Authors:
Nakamura J, Tetsukawa A, Fujiwara S
Citation:
Dev Growth Differ. 2014 Dec 14. doi: 10.1111/dgd.12188. [Epub ahead of print]
Epub:
Yes
Abstract:
Chondroitin sulfate (CS) is a carbohydrate component of proteoglycans. Several types of sulfotransferases determine the pattern...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis (tunicate)
Citation Extract:
Nakamura J, Tetsukawa A, Fujiwara S. Chondroitin 4-O-sulfotransferases are required for cell adhesion and morphogenesis in the Ciona intestinalis embryo. Dev Growth Differ. 2014 Dec 14. doi: 10.1111/dgd.12188. [Epub ahead of print].

Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors

Authors:
Mishra-Gorur K, Çağlayan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümüş GT, Nishimura S, Han W, Tu S, Baran B, Gümüş H, Dilber C, Zaki MS, Hossni HAA, Rivière J-B, Kayserili H, Spencer EG, Rosti RO, Schroth J, Per H, Çağlar C, Çağlar Ç, Dölen D, Baranoski JF, Kumandaş S, Minja FJ, Erson-Omay EZ, Mane SM, Lifton RP, Xu T, Keshishian H, Dobyns WB, Chi NC, Sestan N, Louvi A, Bilgüvar K, Yasuno K, Gleeson JG, Günel M
Citation:
Neuron. 2014. 84(6):1226-39. doi:10.1016/j.neuron.2014.12.014
Epub:
Not Epub
Abstract:
Exome sequencing analysis of over 2,000 children with complex malformations of cortical development identified five independent...
Citation Extract:
Mishra-Gorur K, Çağlayan AO, Schaffer AE, Chabu C, Henegariu O, Vonhoff F, Akgümüş GT, Nishimura S, Han W, Tu S, Baran B, Gümüş H, Dilber C, Zaki MS, Hossni HAA, Rivière J-B, Kayserili H, Spencer EG, Rosti RO, Schroth J, Per H, Çağlar C, Çağlar Ç, Dölen D, Baranoski JF, Kumandaş S, Minja FJ, Erson-Omay EZ, Mane SM, Lifton RP, Xu T, Keshishian H, Dobyns WB, Chi NC, Sestan N, Louvi A, Bilgüvar K, Yasuno K, Gleeson JG, Günel M. Mutations in KATNB1 Cause Complex Cerebral Malformations by Disrupting Asymmetrically Dividing Neural Progenitors. Neuron. 2014. 84(6):1226-39. doi:10.1016/j.neuron.2014.12.014.

Dose-dependent nuclear β-catenin response segregates endomesoderm along the sea star primary axis

Authors:
McCauley BS, Akyar E, Saad HR, Hinman VF
Citation:
Development. 2015;142:207-217. doi:10.1242/dev.113043
Epub:
Not Epub
Abstract:
In many invertebrates, the nuclearization of β-catenin at one pole of the embryo initiates endomesoderm specification. An...
Delivery Method:
microinjection
Organism or Cell Type:
sea star
Citation Extract:
McCauley BS, Akyar E, Saad HR, Hinman VF. Dose-dependent nuclear β-catenin response segregates endomesoderm along the sea star primary axis. Development. 2015;142:207-217. doi:10.1242/dev.113043.

Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency

Authors:
Balasubramanian R, Choi J-H, Francescatto L, Willer J, Horton ER, Asimacopoulos EP, Stankovic KM, Plummer L, Buck CL, Quinton R, Nebesio TD, Mericq V, Merino PM, Meyer BF, Monies D, Gusella JF, Al Tassan N, Katsanis N, Crowley WF Jr
Citation:
PNAS. 2014;111(50):17953-17958. doi:10.1073/pnas.1417438111
Epub:
Not Epub
Abstract:
Inactivating mutations in chromodomain helicase DNA binding protein 7 (CHD7) cause CHARGE syndrome, a severe multiorgan system...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Balasubramanian R, Choi J-H, Francescatto L, Willer J, Horton ER, Asimacopoulos EP, Stankovic KM, Plummer L, Buck CL, Quinton R, Nebesio TD, Mericq V, Merino PM, Meyer BF, Monies D, Gusella JF, Al Tassan N, Katsanis N, Crowley WF Jr. Functionally compromised CHD7 alleles in patients with isolated GnRH deficiency. PNAS. 2014;111(50):17953-17958. doi:10.1073/pnas.1417438111.

Vertical Signalling Involves Transmission of Hox Information from Gastrula Mesoderm to Neurectoderm

Authors:
Bardine N, Lamers G, Wacker S, Donow C, Knoechel W, Durston A
Citation:
PLoS ONE. 2014;9(12):e115208. doi:10.1371/journal.pone.0115208
Epub:
Not Epub
Abstract:
Development and patterning of neural tissue in the vertebrate embryo involves a set of molecules and processes whose...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bardine N, Lamers G, Wacker S, Donow C, Knoechel W, Durston A. Vertical Signalling Involves Transmission of Hox Information from Gastrula Mesoderm to Neurectoderm. PLoS ONE. 2014;9(12):e115208. doi:10.1371/journal.pone.0115208.

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