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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Otoferlin Deficiency In Zebrafish Results In Defects In Balance And Hearing: Rescue Of The Balance And Hearing Phenotype With Full-length And Truncated Forms Of Mouse Otoferlin

Authors:
Chatterjee P, Padmanarayana M, Abdullah N, Holman CL, LaDu J, Tanguay RL, Johnson CP
Citation:
Mol Cell Biol. 2015 Jan 12. pii: MCB.01439-14. [Epub ahead of print]
Epub:
Yes
Abstract:
Sensory hair cells convert mechanical motion into chemical signals. Otoferlin, a six-C2 domain transmembrane protein linked to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chatterjee P, Padmanarayana M, Abdullah N, Holman CL, LaDu J, Tanguay RL, Johnson CP. Otoferlin Deficiency In Zebrafish Results In Defects In Balance And Hearing: Rescue Of The Balance And Hearing Phenotype With Full-length And Truncated Forms Of Mouse Otoferlin. Mol Cell Biol. 2015 Jan 12. pii: MCB.01439-14. [Epub ahead of print].

Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish

Authors:
Kinch CD, Ibhazehiebo K, Jeong J-H, Habibi HR, Kurrasch DM
Citation:
Proc Natl Acad Sci U S A. 2015;[Epub ahead of print] doi:10.1073/pnas.1417731112
Epub:
Yes
Abstract:
Bisphenol A (BPA), a ubiquitous endocrine disruptor that is present in many household products, has been linked to obesity,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kinch CD, Ibhazehiebo K, Jeong J-H, Habibi HR, Kurrasch DM. Low-dose exposure to bisphenol A and replacement bisphenol S induces precocious hypothalamic neurogenesis in embryonic zebrafish. Proc Natl Acad Sci U S A. 2015;[Epub ahead of print] doi:10.1073/pnas.1417731112.

Phosphorylation-Dependent Ubiquitination of Paraxial Protocadherin (PAPC) Controls Gastrulation Cell Movements

Authors:
Kai M, Ueno N, Kinoshita N
Citation:
PLoS ONE. 2015;10(1):e0115111. doi:10.1371/journal.pone.0115111
Epub:
Not Epub
Abstract:
Paraxial protocadherin (PAPC) has been shown to be involved in gastrulation cell movements during early embryogenesis. It is...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Kai M, Ueno N, Kinoshita N. Phosphorylation-Dependent Ubiquitination of Paraxial Protocadherin (PAPC) Controls Gastrulation Cell Movements. PLoS ONE. 2015;10(1):e0115111. doi:10.1371/journal.pone.0115111.

Unexpected link between polyketide synthase and calcium carbonate biomineralization

Authors:
Hojo M, Omi A, Hamanaka G, Shindo K, Shimada A, Kondo M, Narita T, Kiyomoto M, Katsuyama Y, Ohnishi Y, Irie N, Takeda H
Citation:
Zoological Lett. 2015;1:3 doi:10.1186/s40851-014-0001-0
Epub:
Not Epub
Abstract:
Introduction: Calcium carbonate biominerals participate in diverse physiological functions. Despite intensive studies, little...
Delivery Method:
microinjection
Organism or Cell Type:
Medaka and Hemicentrotus pulcherrimus (sea urchin)
Citation Extract:
Hojo M, Omi A, Hamanaka G, Shindo K, Shimada A, Kondo M, Narita T, Kiyomoto M, Katsuyama Y, Ohnishi Y, Irie N, Takeda H. Unexpected link between polyketide synthase and calcium carbonate biomineralization. Zoological Lett. 2015;1:3 doi:10.1186/s40851-014-0001-0.

Duox1-Derived H2O2 Modulates Cxcl8 Expression and Neutrophil Recruitment via JNK/c-JUN/AP-1 Signaling and Chromatin Modifications

Authors:
de Oliveira S, Boudinot P, Calado Â, Mulero V
Citation:
J Immunol. 2015;[Epub ahead of print] doi:10.4049/jimmunol.1402386
Epub:
Not Epub
Abstract:
DUOX1-derived hydrogen peroxide (H2O2) and CXCL8 are two key neutrophil chemoattractants. H2O2 is critical at the early phase,...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
de Oliveira S, Boudinot P, Calado Â, Mulero V. Duox1-Derived H2O2 Modulates Cxcl8 Expression and Neutrophil Recruitment via JNK/c-JUN/AP-1 Signaling and Chromatin Modifications. J Immunol. 2015;[Epub ahead of print] doi:10.4049/jimmunol.1402386 .

Drug-Free Macromolecular Therapeutics Induce Apoptosis of Patient Chronic Lymphocytic Leukemia Cells

Authors:
Chu TW, Kosak KM, Shami PJ, Kopeček J
Citation:
Drug Deliv Transl Res. 2014 Dec;4(5-6):389-394
Epub:
Not Epub
Abstract:
A new drug-free nanotherapeutic approach for B-cell malignancies was developed. Exposure of B-cells to an anti-CD20 Fab'-...
Delivery Method:
cell bathing
Organism or Cell Type:
cell culture: human chronic lymphocytic leukemia cells
Citation Extract:
Chu TW, Kosak KM, Shami PJ, Kopeček J. Drug-Free Macromolecular Therapeutics Induce Apoptosis of Patient Chronic Lymphocytic Leukemia Cells. Drug Deliv Transl Res. 2014 Dec;4(5-6):389-394.

Cdc42 Mediates Bmp-Induced Sprouting Angiogenesis through Fmnl3-Driven Assembly of Endothelial Filopodia in Zebrafish

Authors:
Wakayama Y, Fukuhara S, Ando K, Matsuda M, Mochizuki N
Citation:
Dev Cell. 2015;32(1):109-22. doi:10.1016/j.devcel.2014.11.024
Epub:
Not Epub
Abstract:
During angiogenesis in vivo, endothelial cells (ECs) at the tips of vascular sprouts actively extend filopodia that are filled...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wakayama Y, Fukuhara S, Ando K, Matsuda M, Mochizuki N. Cdc42 Mediates Bmp-Induced Sprouting Angiogenesis through Fmnl3-Driven Assembly of Endothelial Filopodia in Zebrafish. Dev Cell. 2015;32(1):109-22. doi:10.1016/j.devcel.2014.11.024.

Formin-Mediated Actin Polymerization at Endothelial Junctions Is Required for Vessel Lumen Formation and Stabilization

Authors:
Phng L-K, Gebala V, Bentley K, Philippides A, Wacker A, Mathivet T, Sauteur L, Stanchi F, Belting H-G, Affolter M, Gerhardt H
Citation:
Dev Cell. 2015;32(1):123-32. doi:10.1016/j.devcel.2014.11.017
Epub:
Not Epub
Abstract:
During blood vessel formation, endothelial cells (ECs) establish cell-cell junctions and rearrange to form multicellular tubes...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Phng L-K, Gebala V, Bentley K, Philippides A, Wacker A, Mathivet T, Sauteur L, Stanchi F, Belting H-G, Affolter M, Gerhardt H. Formin-Mediated Actin Polymerization at Endothelial Junctions Is Required for Vessel Lumen Formation and Stabilization. Dev Cell. 2015;32(1):123-32. doi:10.1016/j.devcel.2014.11.017.

Making Sense of Anti-Sense Data

Authors:
Stainier DYR, Kontarakis Z, Rossi A
Citation:
Dev Cell. 2015;32(1)7-8. doi:10.1016/j.devcel.2014.12.012
Epub:
Not Epub
Abstract:
The morpholino anti-sense technology has been used extensively to test gene function. The zebrafish model allows a detailed...
Citation Extract:
Stainier DYR, Kontarakis Z, Rossi A. Making Sense of Anti-Sense Data. Dev Cell. 2015;32(1)7-8. doi:10.1016/j.devcel.2014.12.012.

miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins

Authors:
Hudish LI, Blasky AJ, Appel B
Citation:
Dev Cell. 2013 Nov 25;27(4):387-98. doi: 10.1016/j.devcel.2013.10.015. Epub 2013 Nov 14
Epub:
Not Epub
Abstract:
Asymmetric self-renewing division of neural precursors is essential for brain development. Partitioning-defective (Par)...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hudish LI, Blasky AJ, Appel B. miR-219 regulates neural precursor differentiation by direct inhibition of apical par polarity proteins. Dev Cell. 2013 Nov 25;27(4):387-98. doi: 10.1016/j.devcel.2013.10.015. Epub 2013 Nov 14.

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