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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
There are 12156 scientific papers returned from the database with the search filters currently being used below.
Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy
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Citation:
Hum Mol Genet. 2019 Aug 1;28(15):2549-2560. doi: 10.1093/hmg/ddz078. PMID: 30986853; PMCID: PMC6644164 Epub:
Not Epub Abstract:
Nemaline myopathy (NM) is the most common form of congenital myopathy that results in hypotonia and muscle weakness. This... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA. Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy. Hum Mol Genet. 2019 Aug 1;28(15):2549-2560. doi: 10.1093/hmg/ddz078. PMID: 30986853; PMCID: PMC6644164. |
Tfap2a is a novel gatekeeper of nephron differentiation during kidney development
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Citation:
Development. 2019 Jul 10;146(13):dev172387. doi: 10.1242/dev.172387. PMID: 31160420; PMCID: PMC6633607 Epub:
Yes Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 Jul 10;146(13):dev172387. doi: 10.1242/dev.172387. PMID: 31160420; PMCID: PMC6633607. |
Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish
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Citation:
Biol Open. 2019 Jun 5;8(6):bio040683. doi: 10.1242/bio.040683. PMID: 31036752; PMCID: PMC6602327 Epub:
Yes Abstract:
In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C. Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. Biol Open. 2019 Jun 5;8(6):bio040683. doi: 10.1242/bio.040683. PMID: 31036752; PMCID: PMC6602327. |
Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects
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Citation:
Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print] Epub:
Yes Abstract:
MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs that regulate gene expressions by binding to the 3'... Delivery Method:
microinjection Organism or Cell Type:
sea urchin Citation Extract: Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL. Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects. Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print]. |
Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43
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Citation:
Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975 Epub:
Yes Abstract:
The correct positioning of joints in the vertebrate skeleton is not well understood. Mutations in connexin43 (cx43) cause the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bhattacharya S, Gargiulo D, Iovine MK. Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43. Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975. |
The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis
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Citation:
Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print] Epub:
Not Epub Abstract:
Background and aims: It has been well established that ezetimibe blocks cholesterol absorption to prevent the negative effects... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W. The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print]. |
CDK12 regulates DNA repair genes by suppressing intronic polyadenylation
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Citation:
Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y Epub:
Yes Abstract:
Mutations that attenuate homologous recombination (HR)-mediated repair promote tumorigenesis and sensitize cells to... Organism or Cell Type:
cell culture: mouse ES cells Citation Extract: Dubbury SJ, Boutz PL, Sharp PA. CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y. |
Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene
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Citation:
Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11 Epub:
Not Epub Abstract:
Sturgeons (chondrostean, acipenseridae) are ancient fish species, widely known for their caviar. Nowadays, most of them are... Delivery Method:
microinjection Organism or Cell Type:
Acipenser ruthenus (sturgeon) Citation Extract: Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M. Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene. Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11. |
Deletion of Pr72 causes cardiac developmental defects in Zebrafish
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Citation:
PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883 Epub:
Not Epub Abstract:
The alpha regulator subunit B'' of protein phosphatase 2 (PPP2R3A), a regulatory subunit of protein phosphatase 2A (... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F. Deletion of Pr72 causes cardiac developmental defects in Zebrafish. PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883. |
Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo
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Citation:
Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076 Epub:
Not Epub Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise in the embryonic dorsal aorta (DA) through a Runx1-dependent process of... Organism or Cell Type:
zebrafish Citation Extract: Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T. Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo. Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076. |
