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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12156 scientific papers returned from the database with the search filters currently being used below.

Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy

Authors:
Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA
Citation:
Hum Mol Genet. 2019 Aug 1;28(15):2549-2560. doi: 10.1093/hmg/ddz078. PMID: 30986853; PMCID: PMC6644164
Epub:
Not Epub
Abstract:
Nemaline myopathy (NM) is the most common form of congenital myopathy that results in hypotonia and muscle weakness. This...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jirka C, Pak JH, Grosgogeat CA, Marchetii MM, Gupta VA. Dysregulation of NRAP degradation by KLHL41 contributes to pathophysiology in nemaline myopathy. Hum Mol Genet. 2019 Aug 1;28(15):2549-2560. doi: 10.1093/hmg/ddz078. PMID: 30986853; PMCID: PMC6644164.

Tfap2a is a novel gatekeeper of nephron differentiation during kidney development

Authors:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA
Citation:
Development. 2019 Jul 10;146(13):dev172387. doi: 10.1242/dev.172387. PMID: 31160420; PMCID: PMC6633607
Epub:
Yes
Abstract:
Renal functional units known as nephrons undergo patterning events during development that create a segmental array of cellular...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chambers BE, Gerlach GF, Clark EG, Chen KH, Levesque AE, Leshchiner I, Goessling W, Wingert RA. Tfap2a is a novel gatekeeper of nephron differentiation during kidney development. Development. 2019 Jul 10;146(13):dev172387. doi: 10.1242/dev.172387. PMID: 31160420; PMCID: PMC6633607.

Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish

Authors:
Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C
Citation:
Biol Open. 2019 Jun 5;8(6):bio040683. doi: 10.1242/bio.040683. PMID: 31036752; PMCID: PMC6602327
Epub:
Yes
Abstract:
In most vertebrates, including zebrafish, the hypothalamic serotonergic cerebrospinal fluid-contacting (CSF-c) cells constitute...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reuter I, Jäckels J, Kneitz S, Kuper J, Lesch KP, Lillesaar C. Fgf3 is crucial for the generation of monoaminergic cerebrospinal fluid contacting cells in zebrafish. Biol Open. 2019 Jun 5;8(6):bio040683. doi: 10.1242/bio.040683. PMID: 31036752; PMCID: PMC6602327.

Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects

Authors:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL
Citation:
Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print]
Epub:
Yes
Abstract:
MicroRNAs (miRNAs) are highly conserved, small non-coding RNAs that regulate gene expressions by binding to the 3'...
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Sampilo NF, Stepicheva NA, Zaidi SAM, Wang L, Wu W, Wikramanayake A, Song JL. Inhibition of microRNA suppression of Dishevelled results in Wnt pathway associated developmental defects. Development. 2018 Nov 2. pii: dev.167130. doi: 10.1242/dev.167130. [Epub ahead of print].

Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43

Authors:
Bhattacharya S, Gargiulo D, Iovine MK
Citation:
Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975
Epub:
Yes
Abstract:
The correct positioning of joints in the vertebrate skeleton is not well understood. Mutations in connexin43 (cx43) cause the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattacharya S, Gargiulo D, Iovine MK. Simplet-dependent regulation of β-catenin signaling influences skeletal patterning downstream of Cx43. Development. 2018;145:[Epub ahead of print] doi:10.1242/dev.166975.

The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis

Authors:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W
Citation:
Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background and aims: It has been well established that ezetimibe blocks cholesterol absorption to prevent the negative effects...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W. The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print].

CDK12 regulates DNA repair genes by suppressing intronic polyadenylation

Authors:
Dubbury SJ, Boutz PL, Sharp PA
Citation:
Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y
Epub:
Yes
Abstract:
Mutations that attenuate homologous recombination (HR)-mediated repair promote tumorigenesis and sensitize cells to...
Organism or Cell Type:
cell culture: mouse ES cells
Citation Extract:
Dubbury SJ, Boutz PL, Sharp PA. CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y.

Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene

Authors:
Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M
Citation:
Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11
Epub:
Not Epub
Abstract:
Sturgeons (chondrostean, acipenseridae) are ancient fish species, widely known for their caviar. Nowadays, most of them are...
Delivery Method:
microinjection
Organism or Cell Type:
Acipenser ruthenus (sturgeon)
Citation Extract:
Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M. Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene. Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11.

Deletion of Pr72 causes cardiac developmental defects in Zebrafish

Authors:
Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F
Citation:
PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883
Epub:
Not Epub
Abstract:
The alpha regulator subunit B'' of protein phosphatase 2 (PPP2R3A), a regulatory subunit of protein phosphatase 2A (...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F. Deletion of Pr72 causes cardiac developmental defects in Zebrafish. PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883.

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Authors:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T
Citation:
Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076
Epub:
Not Epub
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise in the embryonic dorsal aorta (DA) through a Runx1-dependent process of...
Organism or Cell Type:
zebrafish
Citation Extract:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T. Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo. Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076.

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