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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
There are 12511 scientific papers returned from the database with the search filters currently being used below.
Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14
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Citation:
Cell Discov. 2019;5(1):37 doi:10.1038/s41421-019-0106-x Epub:
Not Epub Abstract:
RNA-binding proteins with intrinsically disordered regions (IDRs) such as Rbm14 can phase separate in vitro. To what extent the... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Xiao Y, Chen J, Wan Y, Gao Q, Jing N, Zheng Y, Zhu X. Regulation of zebrafish dorsoventral patterning by phase separation of RNA-binding protein Rbm14. Cell Discov. 2019;5(1):37 doi:10.1038/s41421-019-0106-x. |
ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response
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Citation:
Nat Commun. 2019 Jul 19;10(1):3195. doi: 10.1038/s41467-019-10967-7 Epub:
Not Epub Abstract:
Genome analysis of diverse human populations has contributed to the identification of novel genomic loci for diseases of major... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Adeyemo AA, Zaghloul NA, Chen G, Doumatey AP, Leitch CC, Hostelley TL, Nesmith JE, Zhou J, Bentley AR, Shriner D, Fasanmade O, Okafor G, Eghan B Jr, Agyenim-Boateng K, Chandrasekharappa S, Adeleye J, Balogun W, Owusu S, Amoah A, Acheampong J, Johnson T, Oli J, Adebamowo C; South Africa Zulu Type 2 Diabetes Case-Control Study, Collins F, Dunston G, Rotimi CN. ZRANB3 is an African-specific type 2 diabetes locus associated with beta-cell mass and insulin response. Nat Commun. 2019 Jul 19;10(1):3195. doi: 10.1038/s41467-019-10967-7. |
Alternative splicing regulates stochastic NLRP3 activity
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Citation:
Nat Commun. 2019 Jul 19;10(1):3238. doi: 10.1038/s41467-019-11076-1 Epub:
Not Epub Abstract:
Leucine-rich repeat (LRR) domains are evolutionarily conserved in proteins that function in development and immunity. Here we... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human monocyte-derived macrophages (hMDMs) Citation Extract: Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Alternative splicing regulates stochastic NLRP3 activity. Nat Commun. 2019 Jul 19;10(1):3238. doi: 10.1038/s41467-019-11076-1. |
Adaptive correction of craniofacial defects in pre-metamorphic Xenopus laevis tadpoles involves thyroid hormone-independent tissue remodeling
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Citation:
Development. 2019 Jul 22;146(14). pii: dev175893. doi: 10.1242/dev.175893 Epub:
Not Epub Abstract:
Although it is well established that some organisms can regenerate lost structures, the ability to remodel existing malformed... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Pinet K, Deolankar M, Leung B, McLaughlin KA. Adaptive correction of craniofacial defects in pre-metamorphic Xenopus laevis tadpoles involves thyroid hormone-independent tissue remodeling. Development. 2019 Jul 22;146(14). pii: dev175893. doi: 10.1242/dev.175893. |
Jmjd6a regulates GSK3β RNA splicing in Xenopus laevis eye development
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Citation:
PLoS One. 2019 Jul 30;14(7):e0219800. doi: 10.1371/journal.pone.0219800. eCollection 2019 Epub:
Not Epub Abstract:
It has been suggested that Jmjd6 plays an important role in gene regulation through its demethylation or hydroxylation activity... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Shin JY, Son J, Kim WS, Gwak J, Ju BG. Jmjd6a regulates GSK3β RNA splicing in Xenopus laevis eye development. PLoS One. 2019 Jul 30;14(7):e0219800. doi: 10.1371/journal.pone.0219800. eCollection 2019. |
Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts
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Citation:
Sci Rep. 2019 Jul 25;9(1):10828. doi: 10.1038/s41598-019-47243-z Epub:
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Joubert syndrome (JBTS) is an incurable multisystem ciliopathy syndrome. The most commonly mutated gene in JBTS patients with a... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: primary human fibroblasts Citation Extract: Molinari E, Ramsbottom SA, Srivastava S, Booth P, Alkanderi S, McLafferty SM, Devlin LA, White K, Gunay-Aygun M, Miles CG, Sayer JA. Targeted exon skipping rescues ciliary protein composition defects in Joubert syndrome patient fibroblasts. Sci Rep. 2019 Jul 25;9(1):10828. doi: 10.1038/s41598-019-47243-z. |
Accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine-seeking behavior
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Citation:
Addict Biol. 2019 Jul 22:e12797. doi: 10.1111/adb.12797. [Epub ahead of print] Epub:
Yes Abstract:
Nicotine self-administration is associated with decreased expression of the glial glutamate transporter (GLT-1) and the cystine... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
rats Citation Extract: Namba MD, Kupchik YM, Spencer SM, Garcia-Keller C, Goenaga JG, Powell GL, Vicino IA, Hogue IB, Gipson CD. Accumbens neuroimmune signaling and dysregulation of astrocytic glutamate transport underlie conditioned nicotine-seeking behavior. Addict Biol. 2019 Jul 22:e12797. doi: 10.1111/adb.12797. [Epub ahead of print]. |
Triptolide preserves glomerular barrier function via the inhibition of p53-mediated increase of GADD45B
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Citation:
Arch Biochem Biophys. 2019 Jul 19;671:210-217. doi: 10.1016/j.abb.2019.07.012. [Epub ahead of print] Epub:
Not Epub Abstract:
Podocytes are important to glomerular filtration barrier integrity and maintenance of size selectivity in protein filtration in... Organism or Cell Type:
zebrafish Citation Extract: Zhai X, Wang L, Xu C, Hou Q, Zhang L, Li Z, Qin W, Liu Z, Chen Z. Triptolide preserves glomerular barrier function via the inhibition of p53-mediated increase of GADD45B. Arch Biochem Biophys. 2019 Jul 19;671:210-217. doi: 10.1016/j.abb.2019.07.012. [Epub ahead of print]. |
Exons 45-55 skipping using mutation-tailored cocktails of antisense morpholinos in the DMD gene
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Citation:
Molec Ther. 2019;[Epub ahead of print] doi:10.1016/j.ymthe.2019.07.012 Epub:
Yes Abstract:
Mutations in the dystrophin (DMD) gene and consequent loss of dystrophin cause Duchenne muscular dystrophy (DMD). A promising... Organism or Cell Type:
cell culture Citation Extract: Echigoya Y, Lim KRQ, Melo D, Bao B, Trieu N, Mizobe Y, Maruyama R, Mamchaoui K, Tanihata J, Aoki Y, Takeda S, Mouly V, Duddy W, Yokota T. Exons 45-55 skipping using mutation-tailored cocktails of antisense morpholinos in the DMD gene. Molec Ther. 2019;[Epub ahead of print] doi:10.1016/j.ymthe.2019.07.012. |
The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection
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Citation:
PLoS Pathog. 2019;15(7):e1007917. doi:10.1371/journal.ppat.1007917 Epub:
Not Epub Abstract:
It is important that bacterium can coordinately deliver several effectors into host cells to disturb the cellular progress... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Yang D, Liu X, Xu W, Gu Z, Yang C, Zhang L, Tan J, Zheng X, Wang Z, Quan S, Zhang Y, Liu Q. The Edwardsiella piscicida thioredoxin-like protein inhibits ASK1-MAPKs signaling cascades to promote pathogenesis during infection. PLoS Pathog. 2019;15(7):e1007917. doi:10.1371/journal.ppat.1007917. |