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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Phosphorylation of ELAVL1 (Ser219/Ser316) mediated by PKC is required for erythropoiesis

Authors:
Zhou X, Wang S, Zheng M, Kuver A, Wan X, Dai K, Li X
Citation:
Biochim Biophys Acta Mol Cell Res. 2018 Nov 2. pii: S0167-4889(18)30494-4. doi: 10.1016/j.bbamcr.2018.10.021. [Epub ahead of print]
Epub:
Yes
Abstract:
Elavl1 (also known as HuR), an RNA binding protein highly conserved between zebrafish and human, regulates gene expression by...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou X, Wang S, Zheng M, Kuver A, Wan X, Dai K, Li X. Phosphorylation of ELAVL1 (Ser219/Ser316) mediated by PKC is required for erythropoiesis. Biochim Biophys Acta Mol Cell Res. 2018 Nov 2. pii: S0167-4889(18)30494-4. doi: 10.1016/j.bbamcr.2018.10.021. [Epub ahead of print].

Quantification of glioblastoma progression in zebrafish xenografts: Adhesion to laminin alpha 5 promotes glioblastoma microtumor formation and inhibits cell invasion

Authors:
Gamble JT, Reed-Harris Y, Barton CL, La Du J, Tanguay R, Greenwood JA
Citation:
Biochem Biophys Res Commun. 2018 Oct 30. pii: S0006-291X(18)32232-0. doi: 10.1016/j.bbrc.2018.10.076. [Epub ahead of print]
Epub:
Yes
Abstract:
Glioblastoma (GBM) is a deadly disease due to its ability to quickly invade and destroy brain tissue. Slowing or stopping GBM...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Gamble JT, Reed-Harris Y, Barton CL, La Du J, Tanguay R, Greenwood JA. Quantification of glioblastoma progression in zebrafish xenografts: Adhesion to laminin alpha 5 promotes glioblastoma microtumor formation and inhibits cell invasion. Biochem Biophys Res Commun. 2018 Oct 30. pii: S0006-291X(18)32232-0. doi: 10.1016/j.bbrc.2018.10.076. [Epub ahead of print].

NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy

Authors:
Watanabe N, Nagata T, Satou Y, Masuda S, Saito T, Kitagawa H, Komaki H, Takagaki K, Takeda S
Citation:
Mol Ther Nucleic Acids. 2018 Sep 27;13:442-449. doi: 10.1016/j.omtn.2018.09.017. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD), the most common lethal heritable childhood disease, is caused by mutations in the DMD gene...
Delivery Method:
electroporation, Endo-Porter
Organism or Cell Type:
cell culture: RD cells, primary DMD fibroblasts
Citation Extract:
Watanabe N, Nagata T, Satou Y, Masuda S, Saito T, Kitagawa H, Komaki H, Takagaki K, Takeda S. NS-065/NCNP-01: An Antisense Oligonucleotide for Potential Treatment of Exon 53 Skipping in Duchenne Muscular Dystrophy. Mol Ther Nucleic Acids. 2018 Sep 27;13:442-449. doi: 10.1016/j.omtn.2018.09.017. [Epub ahead of print].

Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish

Authors:
Reilly ML, Stokman MF, Magry V, Jeanpierre C, Alves M, Paydar M, Hellinga J, Delous M, Pouly D, Failler M, Martinovic J, Loeuillet L, Leroy B, Tantau J, Roume J, Evans CG, Shan X, Filges I, Allingham JS, Kwok BH, Saunier S, Giles RH, Benmerah A
Citation:
Hum Molec Genet. 2018;[Epub ahead of print] doi:10.1093/hmg/ddy381
Epub:
Yes
Abstract:
Mutations in KIF14havepreviously been associated with either severe, isolated or syndromic microcephaly with renal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Reilly ML, Stokman MF, Magry V, Jeanpierre C, Alves M, Paydar M, Hellinga J, Delous M, Pouly D, Failler M, Martinovic J, Loeuillet L, Leroy B, Tantau J, Roume J, Evans CG, Shan X, Filges I, Allingham JS, Kwok BH, Saunier S, Giles RH, Benmerah A. Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish. Hum Molec Genet. 2018;[Epub ahead of print] doi:10.1093/hmg/ddy381.

Prmt7 regulates epiboly and gastrulation cell movements by facilitating syntenin

Authors:
Zhang W, Zhang Y, Li S, Wu Z, Yan Y, Li Y
Citation:
Acta Biochim Biophys Sin (Shanghai). 2018 Nov 1. doi: 10.1093/abbs/gmy136. [Epub ahead of print]
Epub:
Yes
Abstract:
Epiboly spreads and thins the blastoderm over the yolk cell during zebrafish gastrulation. Despite of its fundamental function...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang W, Zhang Y, Li S, Wu Z, Yan Y, Li Y. Prmt7 regulates epiboly and gastrulation cell movements by facilitating syntenin. Acta Biochim Biophys Sin (Shanghai). 2018 Nov 1. doi: 10.1093/abbs/gmy136. [Epub ahead of print].

Naa15 knockdown enhances c2c12 myoblast fusion and induces defects in zebrafish myotome morphogenesis

Authors:
Monestier O, Landemaine A, Bugeon J, Rescan P-Y, Gabillard J-C
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/306563
Epub:
Not Epub
Abstract:
The comprehension of muscle tissue formation and regeneration is essential to develop therapeutic approaches against muscle...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Monestier O, Landemaine A, Bugeon J, Rescan P-Y, Gabillard J-C. Naa15 knockdown enhances c2c12 myoblast fusion and induces defects in zebrafish myotome morphogenesis. bioRxive. 2018;[Preprint] doi:10.1101/306563.

Draxin alters laminin expression during basement membrane reorganization to control cranial neural crest EMT

Authors:
Hutchins EJ, Bronner ME
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/407882
Epub:
Not Epub
Abstract:
Premigratory neural crest cells arise within the dorsal neural tube and subsequently undergo an epithelial-to-mesenchymal...
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Hutchins EJ, Bronner ME. Draxin alters laminin expression during basement membrane reorganization to control cranial neural crest EMT. bioRxive. 2018;[Preprint] doi:10.1101/407882.

Bacterial T6SS Effector EvpP Inhibits Neutrophil Recruitment via Jnk-Caspy Inflammasome Signaling In vivo

Authors:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/453076
Epub:
Not Epub
Abstract:
The type VI secretion system (T6SS) comprises dynamic complex bacterial contractile nanomachines and is used by many bacteria...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tan J, Yang D, Wang Z, Zheng X, Zhang Y, Liu Q. Bacterial T6SS Effector EvpP Inhibits Neutrophil Recruitment via Jnk-Caspy Inflammasome Signaling In vivo. bioRxive. 2018;[Preprint] doi:10.1101/453076.

Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway

Authors:
Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F
Citation:
bioRxiv. 2018;[Preprint] doi:10.1101/459263
Epub:
Not Epub
Abstract:
Alternative splicing (AS) strongly increases proteome diversity and functionality in eukaryotic cells. Protein secretion is a...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture:HEK293T
Citation Extract:
Neumann A, Schindler M, Olofsson D, Wilhelmi I, Schürmann A, Heyd F. Genome-wide identification of alternative splicing events that regulate protein transport across the secretory pathway. bioRxiv. 2018;[Preprint] doi:10.1101/459263 .

The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development

Authors:
Espiritu EB, Crunk AE, Bais A, Hochbaum D, Cervino AS, Phua YL, Butterworth MB, Goto T, Ho J, Hukriede NA, Cirio MC
Citation:
Sci Rep. 2018 Oct 30;8(1):16029. doi:10.1038/s41598-018-34038-x
Epub:
Not Epub
Abstract:
The molecular events driving specification of the kidney have been well characterized. However, how the initial kidney field...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Espiritu EB, Crunk AE, Bais A, Hochbaum D, Cervino AS, Phua YL, Butterworth MB, Goto T, Ho J, Hukriede NA, Cirio MC. The Lhx1-Ldb1 complex interacts with Furry to regulate microRNA expression during pronephric kidney development. Sci Rep. 2018 Oct 30;8(1):16029. doi:10.1038/s41598-018-34038-x.

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