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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis

Authors:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W
Citation:
Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Background and aims: It has been well established that ezetimibe blocks cholesterol absorption to prevent the negative effects...
Link:
https://www.sciencedirect.com/science/article/pii/S0021915018314710
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yan Y, He F, Li Z, Xu R, Li T, Su J, Liu X, Zhao M, Wu W. The important role of apolipoprotein A-II in ezetimibe driven reduction of high cholesterol diet-induced atherosclerosis. Atherosclerosis. 2018 Nov 16;280:99-108. doi: 10.1016/j.atherosclerosis.2018.11.016. [Epub ahead of print].

CDK12 regulates DNA repair genes by suppressing intronic polyadenylation

Authors:
Dubbury SJ, Boutz PL, Sharp PA
Citation:
Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y
Epub:
Yes
Abstract:
Mutations that attenuate homologous recombination (HR)-mediated repair promote tumorigenesis and sensitize cells to...
Link:
https://www.nature.com/articles/s41586-018-0758-y
Organism or Cell Type:
cell culture: mouse ES cells
Citation Extract:
Dubbury SJ, Boutz PL, Sharp PA. CDK12 regulates DNA repair genes by suppressing intronic polyadenylation. Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0758-y.

Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene

Authors:
Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M
Citation:
Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11
Epub:
Not Epub
Abstract:
Sturgeons (chondrostean, acipenseridae) are ancient fish species, widely known for their caviar. Nowadays, most of them are...
Link:
https://www.sciencedirect.com/science/article/pii/S0093691X15003453
Delivery Method:
microinjection
Organism or Cell Type:
Acipenser ruthenus (sturgeon)
Citation Extract:
Linhartová Z, Saito T, Kašpar V, Rodina M, Prášková E, Hagihara S, Pšenička M. Sterilization of sterlet Acipenser ruthenus by using knockdown agent, antisense morpholino oligonucleotide, against dead end gene. Theriogenology. 2015 Oct 15;84(7):1246-1255.e1. doi: 10.1016/j.theriogenology.2015.07.003. Epub 2015 Jul 11.

Deletion of Pr72 causes cardiac developmental defects in Zebrafish

Authors:
Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F
Citation:
PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883
Epub:
Not Epub
Abstract:
The alpha regulator subunit B'' of protein phosphatase 2 (PPP2R3A), a regulatory subunit of protein phosphatase 2A (...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0206883
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Song G, Han M, Li Z, Gan X, Chen X, Yang J, Dong S, Yan M, Wan J, Wang Y, Huang Z, Yin Z, Zheng F. Deletion of Pr72 causes cardiac developmental defects in Zebrafish. PLoS ONE. 2018;13(11):e0206883. doi:10.1371/journal.pone.0206883.

Functional role of pax6 in eye and central nervous system development in the annelid Capitella teleta

Authors:
Klann M, Seaver EC
Citation:
bioRxive. 2018;[preprint] doi:10.1101/481135
Epub:
Not Epub
Abstract:
The transcription factor Pax6 is an important regulator of early animal development. Loss of function mutations of pax6 in a...
Link:
https://www.biorxiv.org/content/early/2018/11/28/481135
Delivery Method:
microinjection
Organism or Cell Type:
Capitella teleta (annelid)
Citation Extract:
Klann M, Seaver EC. Functional role of pax6 in eye and central nervous system development in the annelid Capitella teleta. bioRxive. 2018;[preprint] doi:10.1101/481135.

Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo

Authors:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T
Citation:
Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076
Epub:
Not Epub
Abstract:
Hematopoietic stem and progenitor cells (HSPCs) arise in the embryonic dorsal aorta (DA) through a Runx1-dependent process of...
Link:
http://www.bloodjournal.org/content/132/Suppl_1/330
Organism or Cell Type:
zebrafish
Citation Extract:
Frame JM, Long T, Schuster-Kubaczka C, Esain V, Lim SE, Daley GQ, North T. Inflammasome-Mediated Regulation of Hematopoiesis in the Vertebrate Embryo. Blood. 2018;132:330. doi:10.1182/blood-2018-99-117076.

Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release

Authors:
Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS
Citation:
Nature. 2018 Nov 21. doi: 10.1038/s41586-018-0735-5. [Epub ahead of print]
Epub:
Yes
Abstract:
Development and routine tissue homeostasis require a high turnover of apoptotic cells. These cells are removed by professional...
Link:
https://www.nature.com/articles/s41586-018-0735-5
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Morioka S, Perry JSA, Raymond MH, Medina CB, Zhu Y, Zhao L, Serbulea V, Onengut-Gumuscu S, Leitinger N, Kucenas S, Rathmell JC, Makowski L, Ravichandran KS. Efferocytosis induces a novel SLC program to promote glucose uptake and lactate release. Nature. 2018 Nov 21. doi: 10.1038/s41586-018-0735-5. [Epub ahead of print].

Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates

Authors:
Yan L, Chen J, Zhu X, Sun J, Wu X, Shen W, Zhang W, Tao Q, Meng A
Citation:
Science. 2018;362(6417):eaat1045. doi:10.1126/science.aat1045
Epub:
Yes
Abstract:
The vertebrate body is formed by cell movements and shape change during embryogenesis. It remains undetermined which maternal...
Link:
http://science.sciencemag.org/content/362/6417/eaat1045
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Yan L, Chen J, Zhu X, Sun J, Wu X, Shen W, Zhang W, Tao Q, Meng A. Maternal Huluwa dictates the embryonic body axis through β-catenin in vertebrates. Science. 2018;362(6417):eaat1045. doi:10.1126/science.aat1045.

Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids

Authors:
Erkenbrack EM, Davidson EH, Peter IS
Citation:
Development. 2018 Nov 23. pii: dev.167288. doi: 10.1242/dev.167288. [Epub ahead of print]
Epub:
Yes
Abstract:
Evolution of the animal body plan is driven by changes in developmental gene regulatory networks (GRNs), but how networks...
Link:
http://dev.biologists.org/content/early/2018/11/22/dev.167288.long
Organism or Cell Type:
Eucidaris tribuloides (sea urchin)
Citation Extract:
Erkenbrack EM, Davidson EH, Peter IS. Conserved regulatory state expression controlled by divergent developmental gene regulatory networks in echinoids. Development. 2018 Nov 23. pii: dev.167288. doi: 10.1242/dev.167288. [Epub ahead of print].

Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos

Authors:
Lai JKH, Gagalova K, Stainier DYR
Citation:
bioRxive. 2018;[Preprint] doi:10.1101/479188
Epub:
Not Epub
Abstract:
The phenotypes caused by morpholino-mediated interference of gene function in zebrafish are often not observed in the...
Link:
https://www.biorxiv.org/content/early/2018/11/27/479188
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lai JKH, Gagalova K, Stainier DYR. Induction of Interferon-Stimulated Genes and Cellular Stress Pathways by Morpholinos. bioRxive. 2018;[Preprint] doi:10.1101/479188.

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