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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos

Authors:
Xie S, Jin J, Xu Z, Huang Y, Zhang W, Zhao L, Lo LJ, Peng J, Liu W, Wang F, Shu Q, Zhou T
Citation:
FASEB J. 2018 Nov 26:fj201801235RR. doi: 10.1096/fj.201801235RR. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Centrosomal proteins play critical roles in ciliogenesis. Mutations in many centrosomal proteins have been documented to...
Link:
https://www.fasebj.org/doi/abs/10.1096/fj.201801235RR
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie S, Jin J, Xu Z, Huang Y, Zhang W, Zhao L, Lo LJ, Peng J, Liu W, Wang F, Shu Q, Zhou T. Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos. FASEB J. 2018 Nov 26:fj201801235RR. doi: 10.1096/fj.201801235RR. [Epub ahead of print].

Knockdown of calcium-binding calb2a and calb2b genes indicates the key regulator of the early development of the zebrafish, Danio rerio

Authors:
Bhoyar RC, Jadhao AG, Sabharwal A, Ranjan G, Sivasubbu S, Pinelli C
Citation:
Brain Struct Funct. 2018 Nov 20. doi: 10.1007/s00429-018-1797-8. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The present study initiates our investigation regarding the role of calb2a and calb2b genes that are expressed in the central...
Link:
https://link.springer.com/article/10.1007%2Fs00429-018-1797-8
Organism or Cell Type:
zebrafish
Citation Extract:
Bhoyar RC, Jadhao AG, Sabharwal A, Ranjan G, Sivasubbu S, Pinelli C. Knockdown of calcium-binding calb2a and calb2b genes indicates the key regulator of the early development of the zebrafish, Danio rerio. Brain Struct Funct. 2018 Nov 20. doi: 10.1007/s00429-018-1797-8. [Epub ahead of print].

Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs

Authors:
Li L, Yang J, Soodvilai S, Wang J, Opanasopit P, Kopeček J
Citation:
J Control Release. 2018;[Epub ahead of print] doi:10.1016/j.jconrel.2018.11.015
Epub:
Yes
Abstract:
Chemosensitization strategies have been used to sensitize cancer cells to conventional drugs, but their utility is often...
Link:
https://www.sciencedirect.com/science/article/pii/S0168365918306527
Citation Extract:
Li L, Yang J, Soodvilai S, Wang J, Opanasopit P, Kopeček J. Drug-free albumin-triggered sensitization of cancer cells to anticancer drugs. J Control Release. 2018;[Epub ahead of print] doi:10.1016/j.jconrel.2018.11.015.

Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing

Authors:
Blazquez L, Emmett W, Faraway R, Pineda JMB, Bajew S, Gohr A, Haberman N, Sibley CR, Bradley RK, Irimia M, Ule J
Citation:
Mol Cell. 2018 Nov 1;72(3):496-509.e9. doi: 10.1016/j.molcel.2018.09.033
Epub:
Not Epub
Abstract:
Recursive splicing (RS) starts by defining an "RS-exon," which is then spliced to the preceding exon, thus creating a...
Link:
https://www.cell.com/molecular-cell/fulltext/S1097-2765(18)30832-3
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: HeLa Flp-In T-REx KPNA1, mouse neural precursos cells (NPC)
Citation Extract:
Blazquez L, Emmett W, Faraway R, Pineda JMB, Bajew S, Gohr A, Haberman N, Sibley CR, Bradley RK, Irimia M, Ule J. Exon Junction Complex Shapes the Transcriptome by Repressing Recursive Splicing. Mol Cell. 2018 Nov 1;72(3):496-509.e9. doi: 10.1016/j.molcel.2018.09.033.

Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis

Authors:
Huang C-X, Huang Y, Duan X-K, Zhang M, Tu J-P, Liu J-X, Liu H, Chen T-S, Wang W-M, Wang H-L.
Citation:
Cell Death Differ. 2019 Aug;26(8):1531-1544. doi: 10.1038/s41418-018-0234-0. Epub 2018 Nov 20.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) play significant roles in both embryonic hematopoiesis and hematological malignancy. Zebrafish miR-462-731...
Link:
https://www.nature.com/articles/s41418-018-0234-0
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Huang C-X, Huang Y, Duan X-K, Zhang M, Tu J-P, Liu J-X, Liu H, Chen T-S, Wang W-M, Wang H-L.. Zebrafish miR-462-731 regulates hematopoietic specification and pu.1-dependent primitive myelopoiesis. Cell Death Differ. 2019 Aug;26(8):1531-1544. doi: 10.1038/s41418-018-0234-0. Epub 2018 Nov 20..

VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche

Authors:
Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, Zhou Y, Yao X, Li L, Wu D, Pan W
Citation:
Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0709-7
Epub:
Yes
Abstract:
Haematopoietic stem and progenitor cells (HSPCs) give rise to all blood lineages that support the entire lifespan of...
Link:
https://www.nature.com/articles/s41586-018-0709-7
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Li D, Xue W, Li M, Dong M, Wang J, Wang X, Li X, Chen K, Zhang W, Wu S, Zhang Y, Gao L, Chen Y, Chen J, Zhou BO, Zhou Y, Yao X, Li L, Wu D, Pan W. VCAM-1+ macrophages guide the homing of HSPCs to a vascular niche. Nature. 2018;[Epub ahead of print] doi:10.1038/s41586-018-0709-7.

Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model

Authors:
Ramsbottom SA, Molinari E, Srivastava S, Silberman F, Henry C, Alkanderi S, Devlin LA, White K, Steel DH, Saunier S, Miles CG, Sayer JA
Citation:
Proc Natl Acad Sci U S A. 2018 Nov 16. pii: 201809432. doi: 10.1073/pnas.1809432115. [Epub ahead of print]
Epub:
Yes
Abstract:
Genetic treatments of renal ciliopathies leading to cystic kidney disease would provide a real advance in current therapies....
Link:
http://www.pnas.org/content/early/2018/11/15/1809432115
Delivery Method:
Endo-Porter, Vivo-Morpholino
Organism or Cell Type:
cell culture: human urine-derived renal epithelial kidney cells (hURECs), Cep290Gt mice
Citation Extract:
Ramsbottom SA, Molinari E, Srivastava S, Silberman F, Henry C, Alkanderi S, Devlin LA, White K, Steel DH, Saunier S, Miles CG, Sayer JA. Targeted exon skipping of a CEP290 mutation rescues Joubert syndrome phenotypes in vitro and in a murine model. Proc Natl Acad Sci U S A. 2018 Nov 16. pii: 201809432. doi: 10.1073/pnas.1809432115. [Epub ahead of print].

Lin CY, Zhang PH, Chen YJ, Wu CL, Tsai HJ

Authors:
Conditional Overexpression of rtn4al in Muscle of Adult Zebrafish Displays Defects Similar to Human Amyotrophic Lateral Sclerosis
Citation:
Mar Biotechnol (NY). 2018 Nov 15. doi: 10.1007/s10126-018-9857-x. [Epub ahead of print]
Epub:
Yes
Abstract:
The protein level of muscle-specific human NogoA is abnormally upregulated in amyotrophic lateral sclerosis (ALS) mice and...
Link:
http://link-springer-com-443.webvpn.jxutcm.edu.cn/article/10.1007%2Fs10126-018-9857-x
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Conditional Overexpression of rtn4al in Muscle of Adult Zebrafish Displays Defects Similar to Human Amyotrophic Lateral Sclerosis. Lin CY, Zhang PH, Chen YJ, Wu CL, Tsai HJ. Mar Biotechnol (NY). 2018 Nov 15. doi: 10.1007/s10126-018-9857-x. [Epub ahead of print].

Effects of Thyroid Hormone Disruption on the Ontogenetic Expression of Thyroid Hormone Signaling Genes in Developing Zebrafish (Danio rerio)

Authors:
Walter KM, Miller GW, Chen X, Yaghoobi B, Puschner B, Lein PJ
Citation:
Gen Comp Endocrinol. 2018 Nov 15. pii: S0016-6480(18)30305-8. doi: 10.1016/j.ygcen.2018.11.007. [Epub ahead of print]
Epub:
Yes
Abstract:
Thyroid hormones (THs) regulate neurodevelopment, thus TH disruption is widely posited as a mechanism of developmental...
Link:
https://www.sciencedirect.com/science/article/pii/S0016648018303058
Organism or Cell Type:
zebrafish
Citation Extract:
Walter KM, Miller GW, Chen X, Yaghoobi B, Puschner B, Lein PJ. Effects of Thyroid Hormone Disruption on the Ontogenetic Expression of Thyroid Hormone Signaling Genes in Developing Zebrafish (Danio rerio). Gen Comp Endocrinol. 2018 Nov 15. pii: S0016-6480(18)30305-8. doi: 10.1016/j.ygcen.2018.11.007. [Epub ahead of print].

Characterization of ADP-ribosyl cyclase 1-like (ARC1-like) activity and NAADP signaling during slow muscle cell development in zebrafish embryos

Authors:
Kelu JJ, Webb SE, Galione A, Miller AL
Citation:
Dev Biol. 2018 Nov 14. pii: S0012-1606(18)30508-6. doi: 10.1016/j.ydbio.2018.11.005. [Epub ahead of print]
Epub:
Yes
Abstract:
We recently demonstrated the requirement of two-pore channel type 2 (TPC2)-mediated Ca2+ release during slow muscle cell...
Link:
https://www.sciencedirect.com/science/article/pii/S0012160618305086
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kelu JJ, Webb SE, Galione A, Miller AL. Characterization of ADP-ribosyl cyclase 1-like (ARC1-like) activity and NAADP signaling during slow muscle cell development in zebrafish embryos. Dev Biol. 2018 Nov 14. pii: S0012-1606(18)30508-6. doi: 10.1016/j.ydbio.2018.11.005. [Epub ahead of print].

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