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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
There are 12351 scientific papers returned from the database with the search filters currently being used below.
Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death
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Citation:
Free Radic Biol Med. 2005 Mar 1;38(5):665-77 Epub:
Not Epub Abstract:
Lon now emerges as a major regulator of multiple mitochondrial functions in human beings. Lon catalyzes the degradation of... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: human fibroblasts WI-38 VA-13 Citation Extract: Bota DA, Ngo JK, Davies KJ. Downregulation of the human Lon protease impairs mitochondrial structure and function and causes cell death. Free Radic Biol Med. 2005 Mar 1;38(5):665-77. |
Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication
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Citation:
Genetics. 2008 Dec;180(4):2081-94. Epub 2008 Oct 14 Epub:
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The centriole is the core structure of centrosome and cilium. Failure to restrict centriole duplication to once per cell cycle... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Blachon S, Gopalakrishnan J, Omori Y, Polyanovsky A, Church A, Nicastro D, Malicki J, Avidor-Reiss T. Drosophila asterless and vertebrate Cep152 Are orthologs essential for centriole duplication. Genetics. 2008 Dec;180(4):2081-94. Epub 2008 Oct 14. |
Efficient mapping and cloning of mutations in zebrafish by low-coverage whole-genome sequencing
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Citation:
Genetics. 2012 Mar;190(3):1017-24. doi: 10.1534/genetics.111.136069. Epub 2011 Dec 14 Epub:
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The generation and analysis of mutants in zebrafish has been instrumental in defining the genetic regulation of vertebrate... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bowen ME, Henke K, Siegfried KR, Warman ML, Harris MP. Efficient mapping and cloning of mutations in zebrafish by low-coverage whole-genome sequencing. Genetics. 2012 Mar;190(3):1017-24. doi: 10.1534/genetics.111.136069. Epub 2011 Dec 14. |
Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus
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Citation:
Am J Hum Genet. 2013 Feb 7;92(2):210-20. doi: 10.1016/j.ajhg.2012.12.011. Epub 2013 Jan 17. Epub:
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Genomic rearrangements involving AUTS2 (7q11.22) are associated with autism and intellectual disability (ID), although evidence... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Beunders G, Voorhoeve E, Golzio C, Pardo LM, Rosenfeld JA, Talkowski ME, Simonic I, Lionel AC, Vergult S, Pyatt RE, van de Kamp J, Nieuwint A, Weiss MM, Rizzu P, Verwer LE, van Spaendonk RM, Shen Y, Wu BL, Yu T, Yu Y, Chiang C, Gusella JF, Lindgren AM, Morton CC, van Binsbergen E, Bulk S, van Rossem E, Vanakker O, Armstrong R, Park SM, Greenhalgh L, Maye U, Neill NJ, Abbott KM, Sell S, Ladda R, Farber DM, Bader PI, Cushing T, Drautz JM, Konczal L, Nash P, de Los Reyes E, Carter MT, Hopkins E, Marshall CR, Osborne LR, Gripp KW, Thrush DL, Hashimoto S, Gastier-Foster JM, Astbury C, Ylstra B, Meijers-Heijboer H, Posthuma D, Menten B, Mortier G, Scherer SW, Eichler EE, Girirajan S, Katsanis N, Groffen AJ, Sistermans EA. . Exonic deletions in AUTS2 cause a syndromic form of intellectual disability and suggest a critical role for the C terminus. Am J Hum Genet. 2013 Feb 7;92(2):210-20. doi: 10.1016/j.ajhg.2012.12.011. Epub 2013 Jan 17.. |
Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish
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Citation:
Blood. 2010 Apr 22;115(16):3329-40. Epub 2010 Mar 2 Epub:
Not Epub Abstract:
Mutations in the human nucleophosmin (NPM1) gene are the most frequent genetic alteration in adult acute myeloid leukemias (... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bolli N, Payne EM, Grabher C, Lee JS, Johnston AB, Falini B, Kanki JP, Look AT. Expression of the cytoplasmic NPM1 mutant (NPMc+) causes the expansion of hematopoietic cells in zebrafish. Blood. 2010 Apr 22;115(16):3329-40. Epub 2010 Mar 2. |
Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis
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Citation:
Neurosci Lett. 2007 Jul 11;422(2):97-102. Epub 2007 Jun 2. Epub:
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The Ku70 protein, a product of the XRCC6 gene, is a component of the nonhomologous end-joining (NHEJ) pathway of DNA repair,... Organism or Cell Type:
zebrafish Citation Extract: Bladen CL, Navarre S, Dynan WS, Kozlowski DJ. Expression of the Ku70 subunit (XRCC6) and protection from low dose ionizing radiation during zebrafish embryogenesis. Neurosci Lett. 2007 Jul 11;422(2):97-102. Epub 2007 Jun 2.. |
Factor Associated with Neutral Sphingomyelinase Activity Mediates Navigational Capacity of Leukocytes Responding to Wounds and Infection: Live Imaging Studies in Zebrafish Larvae
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Citation:
J Immunol. 2012 Jul 16. [Epub ahead of print] Epub:
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Factor associated with neutral sphingomyelinase activity (FAN) is an adaptor protein that specifically binds to the p55... Organism or Cell Type:
zebrafish Citation Extract: Boecke A, Sieger D, Neacsu CD, Kashkar H, Krönke M. Factor Associated with Neutral Sphingomyelinase Activity Mediates Navigational Capacity of Leukocytes Responding to Wounds and Infection: Live Imaging Studies in Zebrafish Larvae. J Immunol. 2012 Jul 16. [Epub ahead of print]. |
Fibroblast Growth Factor (FGF) Signaling during Gastrulation Negatively Modulates the Abundance of MicroRNAs That Regulate Proteins Required for Cell Migration and Embryo Patterning
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Citation:
J Biol Chem. 2012;287:38505-38514. doi:10.1074/jbc.M112.400598 Epub:
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FGF signaling plays a pivotal role in regulating cell movements and lineage induction during gastrulation. Here we identify 44... Organism or Cell Type:
chick embryo Citation Extract: Bobbs AS, Saarela AV, Yatskievych TA, Antin PB. Fibroblast Growth Factor (FGF) Signaling during Gastrulation Negatively Modulates the Abundance of MicroRNAs That Regulate Proteins Required for Cell Migration and Embryo Patterning. J Biol Chem. 2012;287:38505-38514. doi:10.1074/jbc.M112.400598. |
Functional Analysis of Wnt Signaling in the Early Sea Urchin Embryo Using mRNA Microinjection
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Citation:
Methods Mol Biol. 2009;469:213-222 Epub:
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The Wnt pathway is a highly conserved signal transduction pathway that plays many critical roles in early animal development.... Delivery Method:
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sea urchin Citation Extract: Bince JM, Wikramanayake AH. Functional Analysis of Wnt Signaling in the Early Sea Urchin Embryo Using mRNA Microinjection. Methods Mol Biol. 2009;469:213-222. |
Gene Knock-down in Rainbow Trout Embryos Using Antisense Morpholino Phosphorodiamidate Oligonucleotides
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Citation:
Marine Biotechnology 2002. 4:256-266 Epub:
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Gene knock-down technology using antisense molecules has many applications for studying gene function, disrupting undesirable... Delivery Method:
Microinjection Organism or Cell Type:
rainbow trout Citation Extract: Boonanuntanasarn S, Yoshizaki G, Takeuchi Y, Morita T, and Takeuchi T. Gene Knock-down in Rainbow Trout Embryos Using Antisense Morpholino Phosphorodiamidate Oligonucleotides. Marine Biotechnology 2002. 4:256-266. |