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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

A Novel Role for Lh3 Dependent ECM Modifications during Neural Crest Cell Migration in Zebrafish

Authors:
Banerjee S, Isaacman-Beck J, Schneider VA, Granato M
Citation:
PLoS ONE. 2013;8(1):e54609. doi:10.1371/journal.pone.0054609
Epub:
Not Epub
Abstract:
During vertebrate development, trunk neural crest cells delaminate along the entire length of the dorsal neural tube and...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Banerjee S, Isaacman-Beck J, Schneider VA, Granato M. A Novel Role for Lh3 Dependent ECM Modifications during Neural Crest Cell Migration in Zebrafish. PLoS ONE. 2013;8(1):e54609. doi:10.1371/journal.pone.0054609.

A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis

Authors:
Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G
Citation:
Mol Cell Biol. 2012 Apr;32(7):1271-83. Epub 2012 Jan 17
Epub:
Not Epub
Abstract:
Despite intensive research, there are very few reagents with which to modulate and dissect the mRNA splicing pathway. Here, we...
Delivery Method:
added to cell-free system
Organism or Cell Type:
cell-free splicing system
Citation Extract:
Berg MG, Wan L, Younis I, Diem MD, Soo M, Wang C, Dreyfuss G. A quantitative high-throughput in vitro splicing assay identifies inhibitors of spliceosome catalysis. Mol Cell Biol. 2012 Apr;32(7):1271-83. Epub 2012 Jan 17.

A switch in numb isoforms is a critical step in cortical development

Authors:
Bani-Yaghoub M, Kubu CJ, Cowling R, Rochira J, Nikopoulos GN, Bellum S, Verdi JM
Citation:
Dev Dyn. 2007 Mar;236(3):696-705.
Epub:
Not Epub
Abstract:
Loss of numb function suggests that numb maintains progenitors in an undifferentiated state. Herein, we demonstrate that numb1...
Citation Extract:
Bani-Yaghoub M, Kubu CJ, Cowling R, Rochira J, Nikopoulos GN, Bellum S, Verdi JM. A switch in numb isoforms is a critical step in cortical development. Dev Dyn. 2007 Mar;236(3):696-705..

A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes

Authors:
Bernhardt ML, Kong BY, Kim AM, O'Halloran TV, Woodruff TK
Citation:
Biol Reprod. 2012 Apr 19;86(4):114. Print 2012 Apr
Epub:
Not Epub
Abstract:
Precise coordination of meiotic progression is a critical determinant of an egg's capacity to be fertilized successfully,...
Citation Extract:
Bernhardt ML, Kong BY, Kim AM, O'Halloran TV, Woodruff TK. A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod. 2012 Apr 19;86(4):114. Print 2012 Apr.

Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish

Authors:
Aspatwar A, Tolvanen MEE, Jokitalo E, Parikka M, Ortutay C, Harjula S-K E, Rämet M, Vihinen M, Parkkila S
Citation:
Hum Mol Genet. 2012;[Epub ahead of print] doi:10.1093/hmg/dds438
Epub:
Not Epub
Abstract:
Congenital ataxia and mental retardation are mainly caused by variations in the genes that affect brain development. Recent...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aspatwar A, Tolvanen MEE, Jokitalo E, Parikka M, Ortutay C, Harjula S-K E, Rämet M, Vihinen M, Parkkila S. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish. Hum Mol Genet. 2012;[Epub ahead of print] doi:10.1093/hmg/dds438.

Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo

Authors:
Behra M, Cousin X, Bertrand C, Vonesch JL, Biellmann D, Chatonnet A, Strahle U
Citation:
Nat Neurosci. 2002 Feb;5(2):111-8
Epub:
Not Epub
Abstract:
The neurotransmitter acetylcholine (ACh) has a crucial role in central and neuromuscular synapses of the cholinergic system....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Behra M, Cousin X, Bertrand C, Vonesch JL, Biellmann D, Chatonnet A, Strahle U. Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo. Nat Neurosci. 2002 Feb;5(2):111-8.

Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis

Authors:
Benato F, Skobo T, Gioacchini G, Moro I, Ciccosanti F, Piacentini M, Fimia GM, Carnevali O, Valle LD
Citation:
Autophagy. 2013 Jan 24;9(4). [Epub ahead of print]
Epub:
Not Epub
Abstract:
AMBRA1 is a positive regulator of the BECN1-dependent program of autophagy recently identified in mouse. In this study, we...
Organism or Cell Type:
zebrafish
Citation Extract:
Benato F, Skobo T, Gioacchini G, Moro I, Ciccosanti F, Piacentini M, Fimia GM, Carnevali O, Valle LD. Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis. Autophagy. 2013 Jan 24;9(4). [Epub ahead of print].

Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery

Authors:
Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X
Citation:
Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The nightmare of multi-drug resistant bacteria will still haunt if no panacea is ever found. Efforts on seeking desirable...
Organism or Cell Type:
Bacteria (review)
Citation Extract:
Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X. Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery. Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print].

Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration

Authors:
Arora V, Iversen PL
Citation:
Drug Metab. And Disp. 2000. 28(2):131-138
Epub:
Not Epub
Abstract:
The rapidly proliferating cells of the regenerating liver after partial hepatectomy (PH) present a reproducible in vivo model...
Delivery Method:
in vivo: injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Arora V, Iversen PL. Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration. Drug Metab. And Disp. 2000. 28(2):131-138.

ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1

Authors:
Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K
Citation:
Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759
Epub:
Not Epub
Abstract:
Despite the clear major contribution of hyperlipidemia to the prevalence of cardiovascular disease in the developed world, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759.

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