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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition

Authors:
Barriga EH, Maxwell PH, Reyes AE, Mayor R
Citation:
J Cell Biol. 2013;201:759-776. doi:10.1083/jcb.201212100
Epub:
Not Epub
Abstract:
One of the most important mechanisms that promotes metastasis is the stabilization of Hif-1 (hypoxia-inducible transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish, Xenopus
Citation Extract:
Barriga EH, Maxwell PH, Reyes AE, Mayor R. The hypoxia factor Hif-1α controls neural crest chemotaxis and epithelial to mesenchymal transition. J Cell Biol. 2013;201:759-776. doi:10.1083/jcb.201212100 .

The involvement of SLC26 anion transporters in chloride uptake in zebrafish (Danio rerio) larvae

Authors:
Bayaa M, Vulesevic B, Esbaugh A, Braun M, Ekker ME, Grosell M, Perry SF
Citation:
J Exp Biol. 2009 Oct;212(Pt 20):3283-95
Epub:
Not Epub
Abstract:
After demonstrating phylogenetic relatedness to orthologous mammalian genes, tools were developed to investigate the roles of...
Organism or Cell Type:
zebrafish
Citation Extract:
Bayaa M, Vulesevic B, Esbaugh A, Braun M, Ekker ME, Grosell M, Perry SF. The involvement of SLC26 anion transporters in chloride uptake in zebrafish (Danio rerio) larvae. J Exp Biol. 2009 Oct;212(Pt 20):3283-95.

The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development

Authors:
Bedell VM, Person AD, Larson JD, McLoon A, Balciunas D, Clark KJ, Neff KI, Nelson KE, Bill BR, Schimmenti LA, Beiraghi S, Ekker SC
Citation:
Development. 2012 Feb;139(4):793-804
Epub:
Not Epub
Abstract:
The Homeobox (Hox) and Paired box (Pax) gene families are key determinants of animal body plans and organ structure. In...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bedell VM, Person AD, Larson JD, McLoon A, Balciunas D, Clark KJ, Neff KI, Nelson KE, Bill BR, Schimmenti LA, Beiraghi S, Ekker SC. The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development. Development. 2012 Feb;139(4):793-804.

The Methyltransferases PRMT4/CARM1 and PRMT5 Control Differentially Myogenesis in Zebrafish

Authors:
Batut J, Duboé C, Vandel L
Citation:
PLoS ONE. 2011;6(10):e25427. doi:10.1371/journal.pone.0025427
Epub:
Not Epub
Abstract:
In vertebrates, skeletal myogenesis involves the sequential activation of myogenic factors to lead ultimately to the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Batut J, Duboé C, Vandel L. The Methyltransferases PRMT4/CARM1 and PRMT5 Control Differentially Myogenesis in Zebrafish. PLoS ONE. 2011;6(10):e25427. doi:10.1371/journal.pone.0025427.

The N-terminal region of CEP290 restores vision in a zebrafish model of human blindness

Authors:
Baye LM, Patrinostro X, Swaminathan S, Beck JS, Zhang Y, Stone EM, Sheffield VC, Slusarski DC
Citation:
Hum Mol Genet. 2011 Jan 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The gene coding for Centrosomal Protein 290 (CEP290), a large multi-domain protein, is the most frequently mutated gene...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Baye LM, Patrinostro X, Swaminathan S, Beck JS, Zhang Y, Stone EM, Sheffield VC, Slusarski DC. The N-terminal region of CEP290 restores vision in a zebrafish model of human blindness. Hum Mol Genet. 2011 Jan 21. [Epub ahead of print].

The Protooncogene c-Myc Is an Essential Regulator of Neural Crest Formation in Xenopus

Authors:
Bellmeyer A, Krase J, Lindgren J, LaBonne C
Citation:
Dev Cell. 2003 Jun;4(6):827-39
Epub:
Not Epub
Abstract:
The neural crest, a population of multipotent progenitor cells, is a defining feature of vertebrate embryos. Neural crest...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bellmeyer A, Krase J, Lindgren J, LaBonne C. The Protooncogene c-Myc Is an Essential Regulator of Neural Crest Formation in Xenopus. Dev Cell. 2003 Jun;4(6):827-39.

The RNA-binding protein XSeb4R regulates maternal Sox3 at the posttranscriptional level during maternal-zygotic transition in Xenopus

Authors:
Bentaya S, Ghogomu SM, Vanhomwegen J, Van Campenhout C, Thelie A, Dhainaut M, Bellefroid E, Souopgui J
Citation:
Dev Biol. 2012 Jan 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The maternal-zygotic transition (MZT) is an embryonic event that overlaps with and plays key roles in primary germ layer...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Bentaya S, Ghogomu SM, Vanhomwegen J, Van Campenhout C, Thelie A, Dhainaut M, Bellefroid E, Souopgui J. The RNA-binding protein XSeb4R regulates maternal Sox3 at the posttranscriptional level during maternal-zygotic transition in Xenopus. Dev Biol. 2012 Jan 11. [Epub ahead of print].

The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo

Authors:
Bauer H, Lele Z, Rauch GJ, Geisler R, Hammerschmidt M
Citation:
Development 2001 128(6):849-858
Epub:
Not Epub
Abstract:
Ventral specification of mesoderm and ectoderm depends on signaling by members of the bone morphogenetic protein (Bmp) family....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bauer H, Lele Z, Rauch GJ, Geisler R, Hammerschmidt M. The type I serine/threonine kinase receptor Alk8/Lost-a-fin is required for Bmp2b/7 signal transduction during dorsoventral patterning of the zebrafish embryo. Development 2001 128(6):849-858.

The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain

Authors:
Begemann G, Schilling TF, Rauch GJ, Geisler R, Ingham PW
Citation:
Development. 2001 Aug;128(16):3081-94
Epub:
Not Epub
Abstract:
We describe a new zebrafish mutation, neckless, and present evidence that it inactivates retinaldehyde dehydrogenase type 2, an...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Begemann G, Schilling TF, Rauch GJ, Geisler R, Ingham PW. The zebrafish neckless mutation reveals a requirement for raldh2 in mesodermal signals that pattern the hindbrain. Development. 2001 Aug;128(16):3081-94.

Therapeutic Potential of Splice-Switching Oligonucleotides

Authors:
Bauman J, Jearawiriyapaisarn N, Kole R
Citation:
Oligonucleotides. 2009 Jan 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Alternative splicing enables a single pre-messenger RNA transcript to yield multiple protein isoforms, making it a major...
Citation Extract:
Bauman J, Jearawiriyapaisarn N, Kole R. Therapeutic Potential of Splice-Switching Oligonucleotides. Oligonucleotides. 2009 Jan 6. [Epub ahead of print].

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