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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12351 scientific papers returned from the database with the search filters currently being used below.

beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2

Authors:
Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS
Citation:
Dev Cell. 2010 Aug 17;19(2):220-31
Epub:
Not Epub
Abstract:
An emerging concept in development is that transcriptional poising presets patterns of gene expression in a manner that...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS. beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev Cell. 2010 Aug 17;19(2):220-31.

BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis

Authors:
Bielen H, Houart C
Citation:
Dev Cell. 2012 Oct 16;23(4):812-22. doi: 10.1016/j.devcel.2012.09.006
Epub:
Not Epub
Abstract:
Depletion of Wnt signaling is a major requirement for the induction of the anterior prosencephalon. However, the molecular...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bielen H, Houart C. BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis. Dev Cell. 2012 Oct 16;23(4):812-22. doi: 10.1016/j.devcel.2012.09.006.

C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling

Authors:
Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, Macrae CA, Rosenzweig A, Spiegelman BM
Citation:
Cell. 2010 Dec 23;143(7):1072-83
Epub:
Not Epub
Abstract:
The heart has the ability to grow in size in response to exercise, but little is known about the transcriptional mechanisms...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, Macrae CA, Rosenzweig A, Spiegelman BM. C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling. Cell. 2010 Dec 23;143(7):1072-83.

Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs

Authors:
Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD
Citation:
PLoS One. 2010 Aug 5;5(8). pii: e11925
Epub:
Not Epub
Abstract:
The accumulation of misfolded proteins within the endoplasmic reticulum (ER) triggers a cellular process known as the Unfolded...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD. Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs. PLoS One. 2010 Aug 5;5(8). pii: e11925.

Caveolin-1 upregulation in diabetic fibroblasts and wounded tissues: implication for understanding the underlying mechanisms of non-healing diabetic ulcers

Authors:
Bitar MS, Abdel-Halim SM, Al-Mulla F
Citation:
Am J Physiol Endocrinol Metab. 2013 Aug 13. [Epub ahead of print]
Epub:
Not Epub
Abstract:
A heightened state of oxidative stress and senescence of fibroblasts constitute potential therapeutic targets in non-healing...
Delivery Method:
Vivo-Morpholino
Citation Extract:
Bitar MS, Abdel-Halim SM, Al-Mulla F. Caveolin-1 upregulation in diabetic fibroblasts and wounded tissues: implication for understanding the underlying mechanisms of non-healing diabetic ulcers. Am J Physiol Endocrinol Metab. 2013 Aug 13. [Epub ahead of print].

Cell Penetrating Peptide Delivery of Splice Directing Oligonucleotides as a Treatment for Duchenne Muscular Dystrophy

Authors:
Betts CA, Wood MJ
Citation:
Curr Pharm Des. 2013;19(16):2948-62. doi: 10.2174/1381612811319160009. PMID: 23140454
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy is a severe, X-linked muscle wasting disorder caused by the absence of an integral structural...
Link:
https://www.eurekaselect.com/article/50268
Delivery Method:
peptide-coupled
Citation Extract:
Betts CA, Wood MJ. Cell Penetrating Peptide Delivery of Splice Directing Oligonucleotides as a Treatment for Duchenne Muscular Dystrophy. Curr Pharm Des. 2013;19(16):2948-62. doi: 10.2174/1381612811319160009. PMID: 23140454.

Chromatin immunoprecipitation in early Xenopus laevis embryos

Authors:
Blythe SA, Reid CD, Kessler DS, Klein PS
Citation:
Dev Dyn. 2009 Jun;238(6):1422-32
Epub:
Not Epub
Abstract:
Chromatin immunoprecipitation (ChIP) is a powerful method for analyzing the interaction of regulatory proteins with genomic...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Blythe SA, Reid CD, Kessler DS, Klein PS. Chromatin immunoprecipitation in early Xenopus laevis embryos. Dev Dyn. 2009 Jun;238(6):1422-32.

Connexin26-mediated transfer of laterality cues in Xenopus

Authors:
Beyer T, Thumberger T, Schweickert A, Blum M
Citation:
Biology Open. 2012; [Epub ahead of print] doi:10.1242/bio.2012760
Epub:
Not Epub
Abstract:
A cilia-driven leftward flow of extracellular fluid breaks bilateral symmetry in the dorsal midline of the neurula stage...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Beyer T, Thumberger T, Schweickert A, Blum M. Connexin26-mediated transfer of laterality cues in Xenopus. Biology Open. 2012; [Epub ahead of print] doi:10.1242/bio.2012760 .

Conserved and acquired features of neurogenin1 regulation

Authors:
Blader P, Lam CS, Rastegar S, Scardigli R, Nicod JC, Simplicio N, Plessy C, Fischer N, Schuurmans C, Guillemot F, Strähle U
Citation:
Development. 2004 Nov;131(22):5627-37. Epub 2004 Oct 20
Epub:
Not Epub
Abstract:
The telencephalon shows vast morphological variations among different vertebrate groups. The transcription factor neurogenin1 (...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blader P, Lam CS, Rastegar S, Scardigli R, Nicod JC, Simplicio N, Plessy C, Fischer N, Schuurmans C, Guillemot F, Strähle U. Conserved and acquired features of neurogenin1 regulation. Development. 2004 Nov;131(22):5627-37. Epub 2004 Oct 20.

Control of chemokine-guided cell migration by ligand sequestration

Authors:
Boldajipour B, Mahabaleshwar H, Kardash E, Reichman-Fried M, Blaser H, Minina S, Wilson D, Xu Q, Raz E
Citation:
Cell. 2008 Feb 8;132(3):463-73
Epub:
Not Epub
Abstract:
Primordial germ cell (PGC) migration in zebrafish is directed by the chemokine SDF-1a that activates its receptor CXCR4b....
Organism or Cell Type:
zebrafish
Citation Extract:
Boldajipour B, Mahabaleshwar H, Kardash E, Reichman-Fried M, Blaser H, Minina S, Wilson D, Xu Q, Raz E. Control of chemokine-guided cell migration by ligand sequestration. Cell. 2008 Feb 8;132(3):463-73.

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