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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity
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Citation:
J Biol Chem. 2007 Jun 15;282(24):17941-52. Epub 2007 Apr 26. Epub:
Not Epub Abstract:
NCF2, the gene encoding the NADPH oxidase cytosolic component p67(phox), is up-regulated by TNF-alpha, and we recently mapped a... Citation Extract: Ammons MC, Siemsen DW, Nelson-Overton LK, Quinn MT, Gauss KA. Binding of pleomorphic adenoma gene-like 2 to the tumor necrosis factor (TNF)-alpha-responsive region of the NCF2 promoter regulates p67(phox) expression and NADPH oxidase activity. J Biol Chem. 2007 Jun 15;282(24):17941-52. Epub 2007 Apr 26. . |
Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin
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Citation:
Toxicol Sci. 2006 Nov;94(1):175-82. Epub 2006 Aug 25. Epub:
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The zebrafish (Danio rerio) has become an attractive vertebrate model for studying developmental processes, and is emerging as... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Antkiewicz DS, Peterson RE, Heideman W. Blocking Expression of AHR2 and ARNT1 in Zebrafish Larvae Protects Against Cardiac Toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Toxicol Sci. 2006 Nov;94(1):175-82. Epub 2006 Aug 25.. |
Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery
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Citation:
PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1204638109 Epub:
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Duchenne muscular dystrophy (DMD), the commonest form of muscular dystrophy, is caused by lack of dystrophin. One of the most... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice, mdx52 Citation Extract: Aoki Y, Yokota T, Nagata T, Nakamura A, Tanihata J, Saito T, Duguez SMR, Nagaraju K, Hoffman EP, Partridge T, Takeda S. Bodywide skipping of exons 45–55 in dystrophic mdx52 mice by systemic antisense delivery. PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1204638109. |
Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis
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Citation:
Development. 2011 Oct;138(19):4267-77. Epub 2011 Aug 18 Epub:
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During development of the central nervous system, the transition from progenitor maintenance to differentiation is directly... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Ali F, Hindley C, McDowell G, Deibler R, Jones A, Kirschner M, Guillemot F, Philpott A. Cell cycle-regulated multi-site phosphorylation of Neurogenin 2 coordinates cell cycling with differentiation during neurogenesis. Development. 2011 Oct;138(19):4267-77. Epub 2011 Aug 18. |
Cell-penetrating-peptide-based delivery of oligonucleotides: an overview
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Citation:
Biochem Soc Trans. 2007 Aug;35(Pt 4):775-9 Epub:
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Cationic CPPs (cell-penetrating peptides) have been used largely for intracellular delivery of low-molecular-mass drugs,... Delivery Method:
peptide-coupled Citation Extract: Abes R, Arzumanov AA, Moulton HM, Abes S, Ivanova GD, Iversen PL, Gait MJ, Lebleu B. Cell-penetrating-peptide-based delivery of oligonucleotides: an overview. Biochem Soc Trans. 2007 Aug;35(Pt 4):775-9. |
Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish
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Dev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9 Epub:
Not Epub Abstract:
Differentiation of insulin producing beta-cells is a genetically well defined process that involves functions of various... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Arkhipova V, Wendik B, Devos N, Ek O, Peers B, Meyer D. Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish. Dev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9. |
Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton
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Development. 2011 Dec;138(23):5135-46. Epub 2011 Oct 26 Epub:
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Bone morphogenetic proteins (BMPs) play crucial roles in craniofacial development but little is known about their interactions... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho KW, Crump JG, Schilling TF. Combinatorial roles for BMPs and Endothelin 1 in patterning the dorsal-ventral axis of the craniofacial skeleton. Development. 2011 Dec;138(23):5135-46. Epub 2011 Oct 26. |
Comparative analysis of antisense oligonucleotide analogs for targeted DMD exon 46 skipping in muscle cells
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Citation:
Gene Ther. 2004 Sep;11(18):1391-8. Epub:
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As small molecule drugs for Duchenne muscular dystrophy (DMD), antisense oligonucleotides (AONs) have been shown to restore the... Delivery Method:
Special Delivery Organism or Cell Type:
Cell culture: primary human myoblast Citation Extract: Aartsma-Rus A, Kaman WE, Bremmer-Bout M, Janson AA, Den Dunnen JT, Van Ommen GJ, Van Deutekom JC. Comparative analysis of antisense oligonucleotide analogs for targeted DMD exon 46 skipping in muscle cells. Gene Ther. 2004 Sep;11(18):1391-8.. |
Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome
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Citation:
Nat Genet. 2012 Feb 26;44(4):435-9, S1-2. doi: 10.1038/ng.1083 Epub:
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The exon-junction complex (EJC) performs essential RNA processing tasks1-5. Here, we describe the first human disorder,... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Albers CA, Paul DS, Schulze H, Freson K, Stephens JC, Smethurst PA, Jolley JD, Cvejic A, Kostadima M, Bertone P, Breuning MH, Debili N, Deloukas P, Favier R, Fiedler J, Hobbs CM, Huang N, Hurles ME, Kiddle G, Krapels I, Nurden P, Ruivenkamp CA, Sambrook JG, Smith K, Stemple DL, Strauss G, Thys C, van Geet C, Newbury-Ecob R, Ouwehand WH, Ghevaert C. Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome. Nat Genet. 2012 Feb 26;44(4):435-9, S1-2. doi: 10.1038/ng.1083. |
Conserved Functions for Mos in Eumetazoan Oocyte Maturation Revealed by Studies in a Cnidarian
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Citation:
Curr Biol. 2009 Feb 18. [Epub ahead of print] Epub:
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The kinase Mos, which activates intracellularly the MAP kinase pathway, is a key regulator of animal oocyte meiotic maturation... Organism or Cell Type:
Clytia hemisphaerica Citation Extract: Amiel A, Leclère L, Robert L, Chevalier S, Houliston E. Conserved Functions for Mos in Eumetazoan Oocyte Maturation Revealed by Studies in a Cnidarian. Curr Biol. 2009 Feb 18. [Epub ahead of print]. |