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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy

Authors:
Beales PL, Bland E, Tobin JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving M, Elcioglu N, Winey M, Tada M, Scambler PJ
Citation:
Nat Genet. 2007 Jun;39(6):727-9. Epub 2007 Apr 29
Epub:
Not Epub
Abstract:
Jeune asphyxiating thoracic dystrophy, an autosomal recessive chondrodysplasia, often leads to death in infancy because of a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Beales PL, Bland E, Tobin JL, Bacchelli C, Tuysuz B, Hill J, Rix S, Pearson CG, Kai M, Hartley J, Johnson C, Irving M, Elcioglu N, Winey M, Tada M, Scambler PJ. IFT80, which encodes a conserved intraflagellar transport protein, is mutated in Jeune asphyxiating thoracic dystrophy. Nat Genet. 2007 Jun;39(6):727-9. Epub 2007 Apr 29.

In vitro organogenesis from undifferentiated cells in Xenopus

Authors:
Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T
Citation:
Dev Dyn. 2009 May 13;238(6):1309-1320. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Amphibians have been used for over a century as experimental animals. In the field of developmental biology in particular, much...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Asashima M, Ito Y, Chan T, Michiue T, Nakanishi M, Suzuki K, Hitachi K, Okabayashi K, Kondow A, Ariizumi T. In vitro organogenesis from undifferentiated cells in Xenopus. Dev Dyn. 2009 May 13;238(6):1309-1320. [Epub ahead of print].

In vivo genome editing using a high-efficiency TALEN system

Authors:
Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug Ii RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, Ekker SC
Citation:
Nature. 2012 Sep 23. doi: 10.1038/nature11537. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The zebrafish (Danio rerio) is increasingly being used to study basic vertebrate biology and human disease with a rich array of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bedell VM, Wang Y, Campbell JM, Poshusta TL, Starker CG, Krug Ii RG, Tan W, Penheiter SG, Ma AC, Leung AY, Fahrenkrug SC, Carlson DF, Voytas DF, Clark KJ, Essner JJ, Ekker SC. In vivo genome editing using a high-efficiency TALEN system. Nature. 2012 Sep 23. doi: 10.1038/nature11537. [Epub ahead of print].

In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling

Authors:
Becker JR, Robinson TY, Sachidanandan C, Kelly AE, Coy S, Peterson RT, MacRae CA
Citation:
Cardiovasc Res. 2012 Mar 1;93(3):463-70. doi: 10.1093/cvr/cvr350. Epub 2011 Dec 23
Epub:
Not Epub
Abstract:
AIMS: Despite increased understanding of the fundamental biology regulating cardiomyocyte hypertrophy and heart failure, it has...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Becker JR, Robinson TY, Sachidanandan C, Kelly AE, Coy S, Peterson RT, MacRae CA. In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling. Cardiovasc Res. 2012 Mar 1;93(3):463-70. doi: 10.1093/cvr/cvr350. Epub 2011 Dec 23.

Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes

Authors:
Asai-Coakwell M, French CR, Ye M, Garcha K, Bigot K, Perera AG, Staehling-Hampton K, Mema SC, Chanda B, Mushegian A, Bamforth S, Doschak MR, Li G, Dobbs MB, Giampietro PF, Brooks BP, Vijayalakshmi P, Sauv� Y, Abitbol M, Sundaresan P, Heyningen VV, Pourquié O, Underhill TM, Waskiewicz AJ, Lehmann OJ.
Citation:
Hum Mol Genet. 2009 Jan 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Proteins of the bone morphogenetic protein (BMP) family are known to have a role in ocular and skeletal development; however,...
Organism or Cell Type:
zebrafish
Citation Extract:
Asai-Coakwell M, French CR, Ye M, Garcha K, Bigot K, Perera AG, Staehling-Hampton K, Mema SC, Chanda B, Mushegian A, Bamforth S, Doschak MR, Li G, Dobbs MB, Giampietro PF, Brooks BP, Vijayalakshmi P, Sauv� Y, Abitbol M, Sundaresan P, Heyningen VV, Pourquié O, Underhill TM, Waskiewicz AJ, Lehmann OJ. . Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes. Hum Mol Genet. 2009 Jan 6. [Epub ahead of print].

Increased DJ-1 Expression under Oxidative Stress and in Alzheimer's Disease Brains

Authors:
Baulac S, Lu H, Strahle J, Yang T, Goldberg MS, Shen J, Schlossmacher MG, Lemere CA, Lu Q, Xia W
Citation:
Mol Neurodegener. 2009 Feb 25;4(1):12. [Epub ahead of print]
Epub:
Not Epub
Abstract:
ABSTRACT: Mutations in the DJ-1 gene have been linked to autosomal recessive familial Parkinson's disease. To understand...
Organism or Cell Type:
zebrafish
Citation Extract:
Baulac S, Lu H, Strahle J, Yang T, Goldberg MS, Shen J, Schlossmacher MG, Lemere CA, Lu Q, Xia W. Increased DJ-1 Expression under Oxidative Stress and in Alzheimer's Disease Brains. Mol Neurodegener. 2009 Feb 25;4(1):12. [Epub ahead of print].

Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor

Authors:
Bartoe JL, Nathanson NM
Citation:
Brain Res Mol Brain Res. 2002 Nov 15;107(2):108-19
Epub:
Not Epub
Abstract:
The neurokine leukemia inhibitory factor (LIF) initiates signaling through heterodimerization of the low affinity LIF receptor...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: IMR32 human neuroblastoma
Citation Extract:
Bartoe JL, Nathanson NM. Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor. Brain Res Mol Brain Res. 2002 Nov 15;107(2):108-19.

Indirect activation of the epithelial Na+ channel by trypsin

Authors:
Bengrine A, Li J, Hamm LL, Awayda MS
Citation:
J Biol Chem. 2007 Sep 14;282(37):26884-96. Epub 2007 Jul 12
Epub:
Not Epub
Abstract:
We tested the hypothesis that the serine protease trypsin can indirectly activate the epithelial Na(+) channel (ENaC)....
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bengrine A, Li J, Hamm LL, Awayda MS. Indirect activation of the epithelial Na+ channel by trypsin. J Biol Chem. 2007 Sep 14;282(37):26884-96. Epub 2007 Jul 12.

Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis, and development

Authors:
Beane WS, Tseng AS, Morokuma J, Lemire JM, Levin M
Citation:
Stem Cells Dev. 2012 Aug 10;21(12):2085-94. doi: 10.1089/scd.2011.0605. Epub 2012 Mar 23
Epub:
Not Epub
Abstract:
The ability to stop producing or replacing cells at the appropriate time is essential, as uncontrolled growth can lead to loss...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Beane WS, Tseng AS, Morokuma J, Lemire JM, Levin M. Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis, and development. Stem Cells Dev. 2012 Aug 10;21(12):2085-94. doi: 10.1089/scd.2011.0605. Epub 2012 Mar 23.

Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart

Authors:
Bendig G, Grimmler M, Huttner IG, Wessels G, Dahme T, Just S, Trano N, Katus HA, Fishman MC, Rottbauer W
Citation:
Genes Dev. 2006 Sep 1;20(17):2361-72. Epub 2006 Aug 18
Epub:
Not Epub
Abstract:
The vertebrate heart possesses autoregulatory mechanisms enabling it first to sense and then to adapt its force of contraction...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bendig G, Grimmler M, Huttner IG, Wessels G, Dahme T, Just S, Trano N, Katus HA, Fishman MC, Rottbauer W. Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. Genes Dev. 2006 Sep 1;20(17):2361-72. Epub 2006 Aug 18.

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