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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system
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Citation:
J Biol Chem. 2006 May 12;281(19):13309-16. Epub 2006 Mar 10 Epub:
Not Epub Abstract:
Zebrafish is a powerful vertebrate model system for using forward genetics to elucidate mechanisms of early development. We... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Azuma M, Toyama R, Laver E, Dawid IB. Perturbation of rRNA synthesis in the bap28 mutation leads to apoptosis mediated by p53 in the zebrafish central nervous system. J Biol Chem. 2006 May 12;281(19):13309-16. Epub 2006 Mar 10. |
Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism
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Citation:
Drug Metab Dispos. 2002 Jul 1;30(7):757-762 Epub:
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Antisense phosphorodiamidate morpholino oligomers (PMO) inhibit targeted gene expression by preventing ribosomal assembly, thus... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: hepatocytes (human primary cells), Caco-2/h3A4 cells Citation Extract: Arora V, Cate ML, Ghosh C, Iversen PL. Phosphorodiamidate Morpholino Antisense Oligomers Inhibit Expression of Human Cytochrome P450 3A4 and Alter Selected Drug Metabolism. Drug Metab Dispos. 2002 Jul 1;30(7):757-762. |
Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab
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Citation:
Genesis. 2013 May 3. doi: 10.1002/dvg.22400. [Epub ahead of print] Epub:
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In mice, homozygous deletion of the cardiac sodium channel Scn5a results in defects in cardiac morphology and embryonic death... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bennett J, Stroud D, Becker J, Roden D. Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab. Genesis. 2013 May 3. doi: 10.1002/dvg.22400. [Epub ahead of print]. |
Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours
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Citation:
Gut. 2010 Aug 23. [Epub ahead of print] Epub:
Not Epub Abstract:
Background Tumour angiogenesis is crucially dependent on the communication between the tumour and the associated endothelium.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mice, NMRI nu/nu Citation Extract: Azoitei N, Pusapati GV, Kleger A, Möller P, Küfer R, Genze F, Wagner M, van Lint J, Carmeliet P, Adler G, Seufferlein T. Protein kinase D2 is a crucial regulator of tumour cell-endothelial cell communication in gastrointestinal tumours. Gut. 2010 Aug 23. [Epub ahead of print]. |
Protein O-mannosylation is necessary for normal embryonic development in zebrafish
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Citation:
Glycobiology. 2010 May 10. [Epub ahead of print] Epub:
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Two distinct cDNAs corresponding to two zebrafish protein O-mannosyltransferase genes, zPOMT1 and zPOMT2, were cloned from... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Avsar-Ban E, Ishikawa H, Manya H, Watanabe M, Akiyama S, Miyake H, Endo T, Tamaru Y. Protein O-mannosylation is necessary for normal embryonic development in zebrafish. Glycobiology. 2010 May 10. [Epub ahead of print]. |
Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5
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Citation:
Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. Epub 2006 May 3. Epub:
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Temporal and spatial differences in extracellular matrix play critical roles in cell proliferation, differentiation and... Delivery Method:
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Cell culture: Rat glomerular mesangial cells Citation Extract: Berfield AK, Hansen K, Abrass CK. Rat glomerular mesangial cells require laminin-9 to migrate in response to insulin-like growth factor binding protein-5. Am J Physiol Cell Physiol. 2006 Oct;291(4):C589-99. Epub 2006 May 3.. |
Redirection of drug metabolism using antisense technology
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Curr Opin Mol Ther. 2001 Jun;3(3):249-57. Review. Epub:
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The cytochrome P450 (CYP) family is the most catalytically versatile component of the phase I oxidation metabolic pathway and... Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Arora V, Iversen PL. Redirection of drug metabolism using antisense technology. Curr Opin Mol Ther. 2001 Jun;3(3):249-57. Review.. |
Responses of Human Cells to PAH-Induced DNA Damage
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Polycyclic Aromatic Compounds . 2002; 22(3-4): 771 - 780 Epub:
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Benzo[a]pyrene (B[a]P) and dibenzo[a,l]pyrene (DB[a,l]P) induce cytochrome P450 (CYP) CYP1A1 and CYP1B1, which metabolize these... Delivery Method:
Special Delivery Organism or Cell Type:
cell culture: human MCF-7 cells Citation Extract: Baird WM, Hooven LA, Mahadevan B, Luch A, Seidel A, Iversen PL. Responses of Human Cells to PAH-Induced DNA Damage. Polycyclic Aromatic Compounds . 2002; 22(3-4): 771 - 780. |
roundabout4 is essential for angiogenesis in vivo
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Citation:
Proc Natl Acad Sci U S A. 2005 May 3;102(18):6373-8. Epub 2005 Apr 22 Epub:
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Stereotypical patterns of vascular and neuronal networks suggest that specific genetic programs tightly control path... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bedell VM, Yeo SY, Park KW, Chung J, Seth P, Shivalingappa V, Zhao J, Obara T, Sukhatme VP, Drummond IA, Li DY, Ramchandran R. roundabout4 is essential for angiogenesis in vivo. Proc Natl Acad Sci U S A. 2005 May 3;102(18):6373-8. Epub 2005 Apr 22. |
Scaling of the BMP activation gradient in Xenopus embryos
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Citation:
Nature. 2008 Jun 26;453(7199):1205-11 Epub:
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In groundbreaking experiments, Hans Spemann demonstrated that the dorsal part of the amphibian embryo can generate a well-... Organism or Cell Type:
Xenopus Citation Extract: Ben-Zvi D, Shilo BZ, Fainsod A, Barkai N. Scaling of the BMP activation gradient in Xenopus embryos. Nature. 2008 Jun 26;453(7199):1205-11. |