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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
There are 12132 scientific papers returned from the database with the search filters currently being used below.
In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling
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Citation:
Cardiovasc Res. 2012 Mar 1;93(3):463-70. doi: 10.1093/cvr/cvr350. Epub 2011 Dec 23 Epub:
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AIMS: Despite increased understanding of the fundamental biology regulating cardiomyocyte hypertrophy and heart failure, it has... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Becker JR, Robinson TY, Sachidanandan C, Kelly AE, Coy S, Peterson RT, MacRae CA. In vivo natriuretic peptide reporter assay identifies chemical modifiers of hypertrophic cardiomyopathy signalling. Cardiovasc Res. 2012 Mar 1;93(3):463-70. doi: 10.1093/cvr/cvr350. Epub 2011 Dec 23. |
Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes
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Citation:
Hum Mol Genet. 2009 Jan 6. [Epub ahead of print] Epub:
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Proteins of the bone morphogenetic protein (BMP) family are known to have a role in ocular and skeletal development; however,... Organism or Cell Type:
zebrafish Citation Extract: Asai-Coakwell M, French CR, Ye M, Garcha K, Bigot K, Perera AG, Staehling-Hampton K, Mema SC, Chanda B, Mushegian A, Bamforth S, Doschak MR, Li G, Dobbs MB, Giampietro PF, Brooks BP, Vijayalakshmi P, Sauv� Y, Abitbol M, Sundaresan P, Heyningen VV, Pourquié O, Underhill TM, Waskiewicz AJ, Lehmann OJ. . Incomplete penetrance and phenotypic variability characterize Gdf6-attributable oculo-skeletal phenotypes. Hum Mol Genet. 2009 Jan 6. [Epub ahead of print]. |
Increased DJ-1 Expression under Oxidative Stress and in Alzheimer's Disease Brains
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Citation:
Mol Neurodegener. 2009 Feb 25;4(1):12. [Epub ahead of print] Epub:
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ABSTRACT: Mutations in the DJ-1 gene have been linked to autosomal recessive familial Parkinson's disease. To understand... Organism or Cell Type:
zebrafish Citation Extract: Baulac S, Lu H, Strahle J, Yang T, Goldberg MS, Shen J, Schlossmacher MG, Lemere CA, Lu Q, Xia W. Increased DJ-1 Expression under Oxidative Stress and in Alzheimer's Disease Brains. Mol Neurodegener. 2009 Feb 25;4(1):12. [Epub ahead of print]. |
Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor
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Citation:
Brain Res Mol Brain Res. 2002 Nov 15;107(2):108-19 Epub:
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The neurokine leukemia inhibitory factor (LIF) initiates signaling through heterodimerization of the low affinity LIF receptor... Delivery Method:
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cell culture: IMR32 human neuroblastoma Citation Extract: Bartoe JL, Nathanson NM. Independent roles of SOCS-3 and SHP-2 in the regulation of neuronal gene expression by leukemia inhibitory factor. Brain Res Mol Brain Res. 2002 Nov 15;107(2):108-19. |
Indirect activation of the epithelial Na+ channel by trypsin
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Citation:
J Biol Chem. 2007 Sep 14;282(37):26884-96. Epub 2007 Jul 12 Epub:
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We tested the hypothesis that the serine protease trypsin can indirectly activate the epithelial Na(+) channel (ENaC).... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bengrine A, Li J, Hamm LL, Awayda MS. Indirect activation of the epithelial Na+ channel by trypsin. J Biol Chem. 2007 Sep 14;282(37):26884-96. Epub 2007 Jul 12. |
Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis, and development
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Citation:
Stem Cells Dev. 2012 Aug 10;21(12):2085-94. doi: 10.1089/scd.2011.0605. Epub 2012 Mar 23 Epub:
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The ability to stop producing or replacing cells at the appropriate time is essential, as uncontrolled growth can lead to loss... Delivery Method:
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Xenopus laevis Citation Extract: Beane WS, Tseng AS, Morokuma J, Lemire JM, Levin M. Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis, and development. Stem Cells Dev. 2012 Aug 10;21(12):2085-94. doi: 10.1089/scd.2011.0605. Epub 2012 Mar 23. |
Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart
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Citation:
Genes Dev. 2006 Sep 1;20(17):2361-72. Epub 2006 Aug 18 Epub:
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The vertebrate heart possesses autoregulatory mechanisms enabling it first to sense and then to adapt its force of contraction... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bendig G, Grimmler M, Huttner IG, Wessels G, Dahme T, Just S, Trano N, Katus HA, Fishman MC, Rottbauer W. Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart. Genes Dev. 2006 Sep 1;20(17):2361-72. Epub 2006 Aug 18. |
Interkinetic nuclear migration and the selection of neurogenic cell divisions during vertebrate retinogenesis
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Citation:
J Neurosci. 2007 Sep 19;27(38):10143-52 Epub:
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During retinal development, neuroepithelial progenitor cells divide in either a symmetric proliferative mode, in which both... Organism or Cell Type:
zebrafish Citation Extract: Baye LM, Link BA. Interkinetic nuclear migration and the selection of neurogenic cell divisions during vertebrate retinogenesis. J Neurosci. 2007 Sep 19;27(38):10143-52. |
Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota
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Citation:
Cell Host Microbe. 2007 Dec 13;2(6):371-82 Epub:
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Vertebrates harbor abundant lipopolysaccharide (LPS) in their gut microbiota. Alkaline phosphatases can dephosphorylate and... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bates JM, Akerlund J, Mittge E, Guillemin K. Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota. Cell Host Microbe. 2007 Dec 13;2(6):371-82. |
Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos
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Citation:
BMC Cell Biol. 2010 Sep 17;11(1):70. [Epub ahead of print] Epub:
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BACKGROUND: Unc-45 is a myosin chaperone and a Hsp90 co-chaperone that plays a key role in muscle development. Genetic and... Organism or Cell Type:
zebrafish Citation Extract: Bernick E, Zhang P, Du S. Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos. BMC Cell Biol. 2010 Sep 17;11(1):70. [Epub ahead of print]. |