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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry

Authors:
Bonapace IM, Latella L, Papait R, Nicassio F, Sacco A, Muto M, Crescenzi M, Di Fiore PP
Citation:
J Cell Biol. 2002 Jun 10;157(6):909-14
Epub:
Not Epub
Abstract:
Terminal differentiation exerts a remarkably tight control on cell proliferation. However, the oncogenic products of DNA tumor...
Delivery Method:
Microinjection
Organism or Cell Type:
cell culture: NIH-3T3 cells
Citation Extract:
Bonapace IM, Latella L, Papait R, Nicassio F, Sacco A, Muto M, Crescenzi M, Di Fiore PP. Np95 is regulated by E1A during mitotic reactivation of terminally differentiated cells and is essential for S phase entry. J Cell Biol. 2002 Jun 10;157(6):909-14.

NR4A2 controls the differentiation of selective dopaminergic nuclei in the zebrafish brain

Authors:
Blin M, Norton W, Bally-Cuif L, Vernier P
Citation:
Mol Cell Neurosci. 2008 Sep 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The orphan nuclear receptor NR4A2/Nurr1 is mandatory for the terminal differentiation of mesencephalic dopamine neurons in...
Organism or Cell Type:
zebrafish
Citation Extract:
Blin M, Norton W, Bally-Cuif L, Vernier P. NR4A2 controls the differentiation of selective dopaminergic nuclei in the zebrafish brain. Mol Cell Neurosci. 2008 Sep 4. [Epub ahead of print].

Numb/Numbl-Opo Antagonism Controls Retinal Epithelium Morphogenesis by Regulating Integrin Endocytosis

Authors:
Bogdanović O, Delfino-Machín M, Nicolás-Pérez M, Gavilán MP, Gago-Rodrigues I, Fernández-Miñán A, Lillo C, Ríos RM, Wittbrodt J, Martínez-Morales JR
Citation:
Dev Cell. 2012 Oct 2. pii: S1534-5807(12)00415-7. doi: 10.1016/j.devcel.2012.09.004. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polarized trafficking of adhesion receptors plays a pivotal role in controlling cellular behavior during morphogenesis....
Delivery Method:
Microinjection
Organism or Cell Type:
medaka
Citation Extract:
Bogdanović O, Delfino-Machín M, Nicolás-Pérez M, Gavilán MP, Gago-Rodrigues I, Fernández-Miñán A, Lillo C, Ríos RM, Wittbrodt J, Martínez-Morales JR. Numb/Numbl-Opo Antagonism Controls Retinal Epithelium Morphogenesis by Regulating Integrin Endocytosis. Dev Cell. 2012 Oct 2. pii: S1534-5807(12)00415-7. doi: 10.1016/j.devcel.2012.09.004. [Epub ahead of print].

Phenothiourea Sensitizes Zebrafish Cranial Neural Crest and Extraocular Muscle Development to Changes in Retinoic Acid and IGF Signaling

Authors:
Bohnsack BL, Gallina D, Kahana A
Citation:
PLoS ONE. 2011;6(8):e22991. doi:10.1371/journal.pone.0022991
Epub:
Not Epub
Abstract:
1-phenyl 2-thiourea (PTU) is a tyrosinase inhibitor commonly used to block pigmentation and aid visualization of zebrafish...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bohnsack BL, Gallina D, Kahana A. Phenothiourea Sensitizes Zebrafish Cranial Neural Crest and Extraocular Muscle Development to Changes in Retinoic Acid and IGF Signaling. PLoS ONE. 2011;6(8):e22991. doi:10.1371/journal.pone.0022991.

Photoreceptor morphology is severely affected in the beta,beta-carotene-15,15'-oxygenase (bcox) zebrafish morphant

Authors:
Biehlmaier O, Lampert JM, Lintig JV, Kohler K
Citation:
Eur J Neurosci. 2005 Jan;21(1):59-68
Epub:
Not Epub
Abstract:
The retinoic acid molecule, a vitamin A derivative, is of key importance for eye and photoreceptor development in vertebrates....
Delivery Method:
Injection
Organism or Cell Type:
zebrafish
Citation Extract:
Biehlmaier O, Lampert JM, Lintig JV, Kohler K. Photoreceptor morphology is severely affected in the beta,beta-carotene-15,15'-oxygenase (bcox) zebrafish morphant. Eur J Neurosci. 2005 Jan;21(1):59-68.

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

Authors:
Betts C, Saleh A, Arzumanov A, Hammond S, Godfrey C, Coursindel T, Gait M, Wood M
Citation:
Mol Ther Nucleic Acids. 2012;[Epub ahead of print] http://dx.doi.org/10.1038/mtna.2012.30
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) are currently the most promising therapeutic intervention for Duchenne muscular dystrophy (DMD...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice (mdx), cultured mdx myotubes
Citation Extract:
Betts C, Saleh A, Arzumanov A, Hammond S, Godfrey C, Coursindel T, Gait M, Wood M. Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment. Mol Ther Nucleic Acids. 2012;[Epub ahead of print] http://dx.doi.org/10.1038/mtna.2012.30.

Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis

Authors:
Bisgrove BW, Snarr BS, Emrazian A, Yost HJ
Citation:
Dev Biol. 2005 Nov 15;287(2):274-88. Epub 2005 Oct 7.
Epub:
Not Epub
Abstract:
Recently, it has become clear that motile cilia play a central role in initiating a left-sided signaling cascade important in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bisgrove BW, Snarr BS, Emrazian A, Yost HJ. Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. Dev Biol. 2005 Nov 15;287(2):274-88. Epub 2005 Oct 7..

Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation

Authors:
Biswas S, Emond MR, Jontes JD
Citation:
JCB. 2010;191(5):1029-41 doi: 10.1083/jcb.201007008
Epub:
Not Epub
Abstract:
The protocadherins comprise the largest subgroup within the cadherin superfamily, yet their cellular and developmental...
Organism or Cell Type:
zebrafish
Citation Extract:
Biswas S, Emond MR, Jontes JD. Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation. JCB. 2010;191(5):1029-41 doi: 10.1083/jcb.201007008.

Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo

Authors:
Bessodes N, Haillot E, Duboc V, Röttinger E, Lahaye F, Lepage T
Citation:
PLoS Genet. 2012;8(12):e1003121. doi:10.1371/journal.pgen.1003121
Epub:
Not Epub
Abstract:
During echinoderm development, expression of nodal on the right side plays a crucial role in positioning of the rudiment on the...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Paracentrotus lividus
Citation Extract:
Bessodes N, Haillot E, Duboc V, Röttinger E, Lahaye F, Lepage T. Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo. PLoS Genet. 2012;8(12):e1003121. doi:10.1371/journal.pgen.1003121.

Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide

Authors:
Bieberich E, MacKinnon S, Silva J, Noggle S, Condie BG
Citation:
J Cell Biol. 2003 Aug 4;162(3):469-79.
Epub:
Not Epub
Abstract:
Cell death and survival of neural progenitor (NP) cells are determined by signals that are largely unknown. We have analyzed...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: Neural progenitor cells from mouse embryonic stem cells
Citation Extract:
Bieberich E, MacKinnon S, Silva J, Noggle S, Condie BG. Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide. J Cell Biol. 2003 Aug 4;162(3):469-79..

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