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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

Extra-embryonic syndecan 2 regulates organ primordia migration and fibrillogenesis throughout the zebrafish embryo

Authors:
Arrington CB, Yost HJ
Citation:
Development. 2009 Sep;136(18):3143-52
Epub:
Not Epub
Abstract:
One of the first steps in zebrafish heart and gut organogenesis is the migration of bilateral primordia to the midline to form...
Organism or Cell Type:
zebrafish
Citation Extract:
Arrington CB, Yost HJ. Extra-embryonic syndecan 2 regulates organ primordia migration and fibrillogenesis throughout the zebrafish embryo. Development. 2009 Sep;136(18):3143-52.

Fishing for a mechanism: using zebrafish to understand spinal muscular atrophy

Authors:
Beattie CE, Carrel TL, McWhorter ML
Citation:
J Child Neurol. 2007 Aug;22(8):995-1003. Review
Epub:
Not Epub
Abstract:
Motoneuron diseases cause paralysis and death due to loss of motoneurons that innervate skeletal muscle. Spinal muscular...
Organism or Cell Type:
zebrafish
Citation Extract:
Beattie CE, Carrel TL, McWhorter ML. Fishing for a mechanism: using zebrafish to understand spinal muscular atrophy. J Child Neurol. 2007 Aug;22(8):995-1003. Review.

FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A

Authors:
Berry FB, Skarie JM, Mirzayans F, Fortin Y, Hudson TJ, Raymond V, Link BA, Walter MA
Citation:
Hum Mol Genet. 2008 Feb 15;17(4):490-505. Epub 2007 Nov 9.
Epub:
Not Epub
Abstract:
Mutations in the human FOXC1 transcription factor gene underlie Axenfeld-Rieger (AR) syndrome, a disorder characterized by...
Organism or Cell Type:
zebrafish
Citation Extract:
Berry FB, Skarie JM, Mirzayans F, Fortin Y, Hudson TJ, Raymond V, Link BA, Walter MA. FOXC1 is required for cell viability and resistance to oxidative stress in the eye through the transcriptional regulation of FOXO1A. Hum Mol Genet. 2008 Feb 15;17(4):490-505. Epub 2007 Nov 9..

FOXD1 Duplication Causes Branchial Defects and Interacts with the TFAP2A Gene Implicated in the Branchio-Oculo-Facial Syndrome in Causing Eye Effects in Zebrafish

Authors:
Balikova I, Devriendt K, Fryns JP, Vermeesch JR
Citation:
Mol Syndromol 2010;1:255-261 DOI: 10.1159/000327707
Epub:
Not Epub
Abstract:
Branchio-oculo-facial syndrome (BOFS) is a rare disorder characterized by maldevelopment of the first and second branchial...
Organism or Cell Type:
zebrafish
Citation Extract:
Balikova I, Devriendt K, Fryns JP, Vermeesch JR. FOXD1 Duplication Causes Branchial Defects and Interacts with the TFAP2A Gene Implicated in the Branchio-Oculo-Facial Syndrome in Causing Eye Effects in Zebrafish. Mol Syndromol 2010;1:255-261 DOI: 10.1159/000327707.

FoxF is essential for FGF-induced migration of heart progenitor cells in the ascidian Ciona intestinalis

Authors:
Beh J, Shi W, Levine M, Davidson B, Christiaen L
Citation:
Development. 2007 Sep;134(18):3297-305
Epub:
Not Epub
Abstract:
Heart development requires precise coordination of morphogenetic movements with progressive cell fate specification and...
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Beh J, Shi W, Levine M, Davidson B, Christiaen L. FoxF is essential for FGF-induced migration of heart progenitor cells in the ascidian Ciona intestinalis. Development. 2007 Sep;134(18):3297-305.

Gata2 provides an early anterior bias and uncovers a global positioning system for polarity in the amniote embryo

Authors:
Bertocchini F, Stern CD
Citation:
Development. 2012 Nov;139(22):4232-8. doi: 10.1242/dev.081901
Epub:
Not Epub
Abstract:
The first axis to be specified during vertebrate development is that between the site where gastrulation will begin and the...
Delivery Method:
Injection then electroporation in vivo
Organism or Cell Type:
chick embryo
Citation Extract:
Bertocchini F, Stern CD. Gata2 provides an early anterior bias and uncovers a global positioning system for polarity in the amniote embryo. Development. 2012 Nov;139(22):4232-8. doi: 10.1242/dev.081901.

GDF6, a Novel Locus for a Spectrum of Ocular Developmental Anomalies

Authors:
Asai-Coakwell M, French CR, Berry KM, Ye M, Koss R, Somerville M, Mueller R, van Heyningen V, Waskiewicz AJ, Lehmann OJ
Citation:
Am J Hum Genet. 2007 Feb;80(2):306-15. Epub 2006 Dec 29
Epub:
Not Epub
Abstract:
Colobomata represent visually impairing ocular closure defects that are associated with a diverse range of developmental...
Citation Extract:
Asai-Coakwell M, French CR, Berry KM, Ye M, Koss R, Somerville M, Mueller R, van Heyningen V, Waskiewicz AJ, Lehmann OJ. GDF6, a Novel Locus for a Spectrum of Ocular Developmental Anomalies. Am J Hum Genet. 2007 Feb;80(2):306-15. Epub 2006 Dec 29.

GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication

Authors:
Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V
Citation:
Nat Cell Biol. 2010 Apr 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Many of the factors required for chromosomal DNA replication have been identified in unicellular eukaryotes. However, DNA...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Balestrini A, Cosentino C, Errico A, Garner E, Costanzo V. GEMC1 is a TopBP1-interacting protein required for chromosomal DNA replication. Nat Cell Biol. 2010 Apr 11. [Epub ahead of print].

Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity

Authors:
Benjamin JM, Torke SJ, Demeler B, McGarry TJ
Citation:
J Biol Chem. 2004 Oct 29;279(44):45957-68. Epub 2004 Aug 12
Epub:
Not Epub
Abstract:
Geminin is an unstable regulatory protein that affects both cell division and cell differentiation. Geminin inhibits a second...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Benjamin JM, Torke SJ, Demeler B, McGarry TJ. Geminin has dimerization, Cdt1-binding, and destruction domains that are required for biological activity. J Biol Chem. 2004 Oct 29;279(44):45957-68. Epub 2004 Aug 12.

Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum

Authors:
Augagneur Y, Wesolowski D, Tae HS, Altman S, Mamoun CB
Citation:
PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1203516109
Epub:
Not Epub
Abstract:
Unique peptide-morpholino oligomer (PMO) conjugates have been designed to bind and promote the cleavage of specific mRNA as a...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Plasmodium falciparum
Citation Extract:
Augagneur Y, Wesolowski D, Tae HS, Altman S, Mamoun CB. Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum. PNAS. 2012;[Epub ahead of print] doi:10.1073/pnas.1203516109 .

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