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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
There are 12245 scientific papers returned from the database with the search filters currently being used below.
A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs
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Citation:
Development. 2011 Sep;138(17):3689-98. Epub 2011 Jul 20 Epub:
Not Epub Abstract:
The otic placode, a specialized region of ectoderm, gives rise to components of the inner ear and shares many characteristics... Delivery Method:
Electroporation Organism or Cell Type:
chick embryo Citation Extract: Betancur P, Sauka-Spengler T, Bronner M. A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs. Development. 2011 Sep;138(17):3689-98. Epub 2011 Jul 20. |
A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development
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Citation:
Invest Ophthalmol Vis Sci. 2011 Nov 28. [Epub ahead of print] Epub:
Not Epub Abstract:
Purpose.The homeobox transcription factor PITX2 is a known regulator of mammalian ocular development, and human PITX2 mutations... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bohnsack BL, Kasprick DS, Kish PE, Goldman D, Kahana A. A zebrafish model of Axenfeld-Rieger Syndrome reveals that pitx2 regulation by retinoic acid is essential for ocular and craniofacial development. Invest Ophthalmol Vis Sci. 2011 Nov 28. [Epub ahead of print]. |
Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation
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Citation:
Development. 2012 Oct;139(19):3499-509. doi: 10.1242/dev.079582. Epub 2012 Aug 16 Epub:
Not Epub Abstract:
Continuous neurogenesis in the adult nervous system requires a delicate balance between proliferation and differentiation.... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Borday C, Cabochette P, Parain K, Mazurier N, Janssens S, Tran HT, Sekkali B, Bronchain O, Vleminckx K, Locker M, Perron M. Antagonistic cross-regulation between Wnt and Hedgehog signalling pathways controls post-embryonic retinal proliferation. Development. 2012 Oct;139(19):3499-509. doi: 10.1242/dev.079582. Epub 2012 Aug 16. |
Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis
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Citation:
PLoS Genet. 2013;9(2):e1003279. doi:10.1371/journal.pgen.1003279 Epub:
Not Epub Abstract:
Ribosome biogenesis underpins cell growth and division. Disruptions in ribosome biogenesis and translation initiation are... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Boglev Y, Badrock AP, Trotter AJ, Du Q, Richardson EJ, Parslow AC, Markmiller SJ, Hall NE, de Jong-Curtain TA, Ng AY, Verkade H, Ober EA, Field HA, Shin D, Shin CH, Hannan KM, Hannan RD, Pearson RB, Kim S-H, Ess KC, Lieschke GJ, Stainier DYR, Heath JK. Autophagy Induction Is a Tor- and Tp53-Independent Cell Survival Response in a Zebrafish Model of Disrupted Ribosome Biogenesis. PLoS Genet. 2013;9(2):e1003279. doi:10.1371/journal.pgen.1003279. |
beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2
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Citation:
Dev Cell. 2010 Aug 17;19(2):220-31 Epub:
Not Epub Abstract:
An emerging concept in development is that transcriptional poising presets patterns of gene expression in a manner that... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus Citation Extract: Blythe SA, Cha SW, Tadjuidje E, Heasman J, Klein PS. beta-Catenin primes organizer gene expression by recruiting a histone H3 arginine 8 methyltransferase, Prmt2. Dev Cell. 2010 Aug 17;19(2):220-31. |
BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis
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Citation:
Dev Cell. 2012 Oct 16;23(4):812-22. doi: 10.1016/j.devcel.2012.09.006 Epub:
Not Epub Abstract:
Depletion of Wnt signaling is a major requirement for the induction of the anterior prosencephalon. However, the molecular... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bielen H, Houart C. BMP Signaling Protects Telencephalic Fate by Repressing Eye Identity and Its Cxcr4-Dependent Morphogenesis. Dev Cell. 2012 Oct 16;23(4):812-22. doi: 10.1016/j.devcel.2012.09.006. |
C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling
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Citation:
Cell. 2010 Dec 23;143(7):1072-83 Epub:
Not Epub Abstract:
The heart has the ability to grow in size in response to exercise, but little is known about the transcriptional mechanisms... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Boström P, Mann N, Wu J, Quintero PA, Plovie ER, Panáková D, Gupta RK, Xiao C, Macrae CA, Rosenzweig A, Spiegelman BM. C/EBPβ Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling. Cell. 2010 Dec 23;143(7):1072-83. |
Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs
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Citation:
PLoS One. 2010 Aug 5;5(8). pii: e11925 Epub:
Not Epub Abstract:
The accumulation of misfolded proteins within the endoplasmic reticulum (ER) triggers a cellular process known as the Unfolded... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Bollo M, Paredes RM, Holstein D, Zheleznova N, Camacho P, Lechleiter JD. Calcineurin Interacts with PERK and Dephosphorylates Calnexin to Relieve ER Stress in Mammals and Frogs. PLoS One. 2010 Aug 5;5(8). pii: e11925. |
Caveolin-1 upregulation in diabetic fibroblasts and wounded tissues: implication for understanding the underlying mechanisms of non-healing diabetic ulcers
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Citation:
Am J Physiol Endocrinol Metab. 2013 Aug 13. [Epub ahead of print] Epub:
Not Epub Abstract:
A heightened state of oxidative stress and senescence of fibroblasts constitute potential therapeutic targets in non-healing... Delivery Method:
Vivo-Morpholino Citation Extract: Bitar MS, Abdel-Halim SM, Al-Mulla F. Caveolin-1 upregulation in diabetic fibroblasts and wounded tissues: implication for understanding the underlying mechanisms of non-healing diabetic ulcers. Am J Physiol Endocrinol Metab. 2013 Aug 13. [Epub ahead of print]. |
Cell Penetrating Peptide Delivery of Splice Directing Oligonucleotides as a Treatment for Duchenne Muscular Dystrophy
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Citation:
Curr Pharm Des. 2012 Nov 2. [Epub ahead of print] Epub:
Not Epub Abstract:
Duchenne muscular dystrophy is a severe, X-linked muscle wasting disorder caused by the absence of an integral structural... Delivery Method:
peptide-coupled Citation Extract: Betts CA, Wood MJ. Cell Penetrating Peptide Delivery of Splice Directing Oligonucleotides as a Treatment for Duchenne Muscular Dystrophy. Curr Pharm Des. 2012 Nov 2. [Epub ahead of print]. |