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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12132 scientific papers returned from the database with the search filters currently being used below.

A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes

Authors:
Bernhardt ML, Kong BY, Kim AM, O'Halloran TV, Woodruff TK
Citation:
Biol Reprod. 2012 Apr 19;86(4):114. Print 2012 Apr
Epub:
Not Epub
Abstract:
Precise coordination of meiotic progression is a critical determinant of an egg's capacity to be fertilized successfully,...
Citation Extract:
Bernhardt ML, Kong BY, Kim AM, O'Halloran TV, Woodruff TK. A zinc-dependent mechanism regulates meiotic progression in mammalian oocytes. Biol Reprod. 2012 Apr 19;86(4):114. Print 2012 Apr.

Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish

Authors:
Aspatwar A, Tolvanen MEE, Jokitalo E, Parikka M, Ortutay C, Harjula S-K E, Rämet M, Vihinen M, Parkkila S
Citation:
Hum Mol Genet. 2012;[Epub ahead of print] doi:10.1093/hmg/dds438
Epub:
Not Epub
Abstract:
Congenital ataxia and mental retardation are mainly caused by variations in the genes that affect brain development. Recent...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Aspatwar A, Tolvanen MEE, Jokitalo E, Parikka M, Ortutay C, Harjula S-K E, Rämet M, Vihinen M, Parkkila S. Abnormal cerebellar development and ataxia in CARP VIII morphant zebrafish. Hum Mol Genet. 2012;[Epub ahead of print] doi:10.1093/hmg/dds438.

Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo

Authors:
Behra M, Cousin X, Bertrand C, Vonesch JL, Biellmann D, Chatonnet A, Strahle U
Citation:
Nat Neurosci. 2002 Feb;5(2):111-8
Epub:
Not Epub
Abstract:
The neurotransmitter acetylcholine (ACh) has a crucial role in central and neuromuscular synapses of the cholinergic system....
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Behra M, Cousin X, Bertrand C, Vonesch JL, Biellmann D, Chatonnet A, Strahle U. Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo. Nat Neurosci. 2002 Feb;5(2):111-8.

Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis

Authors:
Benato F, Skobo T, Gioacchini G, Moro I, Ciccosanti F, Piacentini M, Fimia GM, Carnevali O, Valle LD
Citation:
Autophagy. 2013 Jan 24;9(4). [Epub ahead of print]
Epub:
Not Epub
Abstract:
AMBRA1 is a positive regulator of the BECN1-dependent program of autophagy recently identified in mouse. In this study, we...
Organism or Cell Type:
zebrafish
Citation Extract:
Benato F, Skobo T, Gioacchini G, Moro I, Ciccosanti F, Piacentini M, Fimia GM, Carnevali O, Valle LD. Ambra1 knockdown in zebrafish leads to incomplete development due to severe defects in organogenesis. Autophagy. 2013 Jan 24;9(4). [Epub ahead of print].

Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery

Authors:
Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X
Citation:
Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The nightmare of multi-drug resistant bacteria will still haunt if no panacea is ever found. Efforts on seeking desirable...
Organism or Cell Type:
Bacteria (review)
Citation Extract:
Bai H, Xue X, Hou Z, Zhou Y, Meng J, Luo X. Antisense Antibiotics: A Brief Review of Novel Target Discovery and Delivery. Curr Drug Discov Technol. 2010 Sep 14. [Epub ahead of print].

Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration

Authors:
Arora V, Iversen PL
Citation:
Drug Metab. And Disp. 2000. 28(2):131-138
Epub:
Not Epub
Abstract:
The rapidly proliferating cells of the regenerating liver after partial hepatectomy (PH) present a reproducible in vivo model...
Delivery Method:
in vivo: injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Arora V, Iversen PL. Antisense oligonucleotides targeted to the p53 gene modulate rat liver regeneration. Drug Metab. And Disp. 2000. 28(2):131-138.

ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1

Authors:
Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K
Citation:
Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759
Epub:
Not Epub
Abstract:
Despite the clear major contribution of hyperlipidemia to the prevalence of cardiovascular disease in the developed world, the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Avraham-Davidi I, Ely Y, Pham VN, Castranova D, Grunspan M, Malkinson G, Gibbs-Bar L, Mayseless O, Allmog G, Lo B, Warren CM, Chen TT, Ungos J, Kidd K, Shaw K, Rogachev I, Wan W, Murphy PM, Farber SA, Carmel L, Shelness GS, Iruela-Arispe ML, Weinstein BM, Yaniv K. ApoB-containing lipoproteins regulate angiogenesis by modulating expression of VEGF receptor 1. Nat Med. 2012;[Epub ahead of print] doi:10.1038/nm.2759.

Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats

Authors:
Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL.
Citation:
J Pharm Sci. 2002 Apr;91(4):1009-18
Epub:
Not Epub
Abstract:
Antisense phosphorodiamidate Morpholino oligomers (PMO) are resistant to degradation by cellular hydrolases, DNases, RNases,...
Delivery Method:
in vivo: injection
Organism or Cell Type:
rats, Sprague Dawley
Citation Extract:
Arora V, Knapp DC, Reddy MT, Weller DD, Iversen PL.. Bioavailability and efficacy of antisense morpholino oligomers targeted to c-myc and cytochrome P-450 3A2 following oral administration in rats. J Pharm Sci. 2002 Apr;91(4):1009-18.

Brain selective transgene expression in zebrafish using an NRSE derived motif

Authors:
Bergeron SA, Hannan MC, Codore H, Fero K, Li G, Moak ZB, Yokogawa T, Burgess HA
Citation:
Front Neur Circuits. 2012;6(00110). doi:10.3389/fncir.2012.00110
Epub:
Not Epub
Abstract:
Transgenic technologies enable the manipulation and observation of circuits controlling behavior by permitting expression of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bergeron SA, Hannan MC, Codore H, Fero K, Li G, Moak ZB, Yokogawa T, Burgess HA. Brain selective transgene expression in zebrafish using an NRSE derived motif. Front Neur Circuits. 2012;6(00110). doi:10.3389/fncir.2012.00110.

Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish

Authors:
Bergeron SA, Tyurina OV, Miller E, Bagas A, Karlstrom RO
Citation:
Development. 2011 Jan;138(1):75-85. Epub 2010 Nov 29
Epub:
Not Epub
Abstract:
The transmembrane protein Brother of Cdo (Boc) has been implicated in Shh-mediated commissural axon guidance, and can both...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bergeron SA, Tyurina OV, Miller E, Bagas A, Karlstrom RO. Brother of cdo (umleitung) is cell-autonomously required for Hedgehog-mediated ventral CNS patterning in the zebrafish. Development. 2011 Jan;138(1):75-85. Epub 2010 Nov 29.

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