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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12095 scientific papers returned from the database with the search filters currently being used below.

Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling

Authors:
Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E
Citation:
Development. 2013 Oct;140(20):4177-4181. Epub 2013 Sep 11
Epub:
Not Epub
Abstract:
One of the earliest steps in embryonic development is the specification of the germ layers, the subdivision of the blastula...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bates TJ, Vonica A, Heasman J, Brivanlou AH, Bell E. Coco regulates dorsoventral specification of germ layers via inhibition of TGFβ signalling. Development. 2013 Oct;140(20):4177-4181. Epub 2013 Sep 11.

Cofilin-1 Inactivation Leads to Proteinuria - Studies in Zebrafish, Mice and Humans

Authors:
Ashworth S, Teng B, Kaufeld J, Miller E, Tossidou I, Englert C, Bollig F, Staggs L, Roberts IS, Park JK, Haller H, Schiffer M
Citation:
PLoS One. 2010 Sep 8;5(9). pii: e12626
Epub:
Not Epub
Abstract:
BACKGROUND: Podocytes are highly specialized epithelial cells on the visceral side of the glomerulus. Their interdigitating...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ashworth S, Teng B, Kaufeld J, Miller E, Tossidou I, Englert C, Bollig F, Staggs L, Roberts IS, Park JK, Haller H, Schiffer M. Cofilin-1 Inactivation Leads to Proteinuria - Studies in Zebrafish, Mice and Humans. PLoS One. 2010 Sep 8;5(9). pii: e12626.

Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes

Authors:
Augello MA, Burd CJ, Birbe R, McNair C, Ertel A, Magee MS, Frigo DE, Wilder-Romans K, Shilkrut M, Han S, Jernigan DL, Dean JL, Fatatis A, McDonnell DP, Visakorpi T, Feng FY, Knudsen KE
Citation:
J Clin Invest. 2013 Jan 2;123(1):493-508. doi: 10.1172/JCI64750. Epub 2012 Dec 21.
Epub:
Not Epub
Abstract:
Cyclin D1b is a splice variant of the cell cycle regulator cyclin D1 and is known to harbor divergent and highly oncogenic...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: human LNCaP cancer cell line
Citation Extract:
Augello MA, Burd CJ, Birbe R, McNair C, Ertel A, Magee MS, Frigo DE, Wilder-Romans K, Shilkrut M, Han S, Jernigan DL, Dean JL, Fatatis A, McDonnell DP, Visakorpi T, Feng FY, Knudsen KE. Convergence of oncogenic and hormone receptor pathways promotes metastatic phenotypes. J Clin Invest. 2013 Jan 2;123(1):493-508. doi: 10.1172/JCI64750. Epub 2012 Dec 21..

Craniofacial cartilage morphogenesis requires zebrafish col11a1 activity

Authors:
Baas D, Malbouyres M, Haftek-Terreau Z, Le Guellec D, Ruggiero F
Citation:
Matrix Biol. 2009 Jul 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The zebrafish ortholog of the human COL11A1 gene encoding the cartilage collagen XI proalpha1 chain was characterized to...
Organism or Cell Type:
zebrafish
Citation Extract:
Baas D, Malbouyres M, Haftek-Terreau Z, Le Guellec D, Ruggiero F. Craniofacial cartilage morphogenesis requires zebrafish col11a1 activity. Matrix Biol. 2009 Jul 25. [Epub ahead of print].

CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development

Authors:
Backer CB, Gutzman JH, Pearson CG, Cheeseman IM
Citation:
Mol Biol Cell. 2012 Apr 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The diverse populations of microtubule polymers in cells are functionally distinguished by different posttranslational...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Backer CB, Gutzman JH, Pearson CG, Cheeseman IM. CSAP localizes to polyglutamylated microtubules and promotes proper cilia function and zebrafish development. Mol Biol Cell. 2012 Apr 4. [Epub ahead of print].

Cse1l Is a Negative Regulator of CFTR-Dependent Fluid Secretion

Authors:
Bagnat M, Navis A, Herbstreith S, Brand-Arzamendi K, Curado S, Gabriel S, Mostov K, Huisken J, Stainier DYR
Citation:
Current Biology. 2010; ISSN 0960-9822, DOI: 10.1016/j.cub.2010.09.012 [Epub 7 October]
Epub:
Not Epub
Abstract:
Transport of chloride through the cystic fibrosis transmembrane conductance regulator (CFTR) channel is a key step in...
Organism or Cell Type:
zebrafish
Citation Extract:
Bagnat M, Navis A, Herbstreith S, Brand-Arzamendi K, Curado S, Gabriel S, Mostov K, Huisken J, Stainier DYR. Cse1l Is a Negative Regulator of CFTR-Dependent Fluid Secretion. Current Biology. 2010; ISSN 0960-9822, DOI: 10.1016/j.cub.2010.09.012 [Epub 7 October].

Cyclin E morpholino delays embryogenesis in Xenopus

Authors:
Audic Y, Boyle B, Slevin M, Hartley RS
Citation:
Genesis. 2001 Jul;30(3):107-9
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Audic Y, Boyle B, Slevin M, Hartley RS. Cyclin E morpholino delays embryogenesis in Xenopus. Genesis. 2001 Jul;30(3):107-9.

DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis

Authors:
Barton CE, Tahinci E, Barbieri CE, Johnson KN, Hanson AJ, Jernigan KK, Chen TW, Lee E, Pietenpol JA
Citation:
Dev Biol. 2009 Mar 6. [Epub ahead of print]
Epub:
Not Epub
Abstract:
p63, a homolog of the tumor suppressor p53, is critical for the development and maintenance of complex epithelia. The...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Barton CE, Tahinci E, Barbieri CE, Johnson KN, Hanson AJ, Jernigan KK, Chen TW, Lee E, Pietenpol JA. DeltaNp63 antagonizes p53 to regulate mesoderm induction in Xenopus laevis. Dev Biol. 2009 Mar 6. [Epub ahead of print].

Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish

Authors:
Belele CL, English MA, Chahal J, Burnetti A, Finckbeiner SM, Gibney G, Kirby M, Sood R, Liu P
Citation:
Blood. 2009 Oct 20. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The transcription factor Gata1 is required for the development of erythrocytes and megakaryocytes. Previous studies with a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Belele CL, English MA, Chahal J, Burnetti A, Finckbeiner SM, Gibney G, Kirby M, Sood R, Liu P. Differential requirement for Gata1 DNA binding and transactivation between primitive and definitive stages of hematopoiesis in zebrafish. Blood. 2009 Oct 20. [Epub ahead of print].

Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart

Authors:
Baker K, Holtzman NG, Burdine RD
Citation:
Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13924-9. Epub 2008 Sep 10
Epub:
Not Epub
Abstract:
The Nodal signaling pathway plays a conserved role in determining left-sided identity in vertebrates with this early left-right...
Organism or Cell Type:
zebrafish
Citation Extract:
Baker K, Holtzman NG, Burdine RD. Direct and indirect roles for Nodal signaling in two axis conversions during asymmetric morphogenesis of the zebrafish heart. Proc Natl Acad Sci U S A. 2008 Sep 16;105(37):13924-9. Epub 2008 Sep 10.

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