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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes

Authors:
Brunet S, Dumont J, Lee KW, Kinoshita K, Hikal P, Gruss OJ, Maro B, Verlhac MH
Citation:
PLoS ONE. 2008 Oct 3;3(10):e3338
Epub:
Not Epub
Abstract:
Formation of female gametes requires acentriolar spindle assembly during meiosis. Mitotic spindles organize from centrosomes...
Delivery Method:
Microinjection
Organism or Cell Type:
mouse oocytes
Citation Extract:
Brunet S, Dumont J, Lee KW, Kinoshita K, Hikal P, Gruss OJ, Maro B, Verlhac MH. Meiotic regulation of TPX2 protein levels governs cell cycle progression in mouse oocytes. PLoS ONE. 2008 Oct 3;3(10):e3338.

Missense mutations in β-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome

Authors:
Buysse K, Riemersma M, Powell G, van Reeuwijk J, Chitayat D, Roscioli T, Kamsteeg E-J, van den Elzen C, van Beusekom E, Blaser S, Babul-Hirji R, Halliday W, Wright GJ, Stemple DL, Lin Y-Y, Lefeber DJ, van Bokhoven H
Citation:
Hum Mol Genet. 2013;[Epub ahead of print] doi:10.1093/hmg/ddt021
Epub:
Not Epub
Abstract:
Several known or putative glycosyltransferases are required for the synthesis of laminin-binding glycans on alpha-dystroglycan...
Organism or Cell Type:
zebrafish
Citation Extract:
Buysse K, Riemersma M, Powell G, van Reeuwijk J, Chitayat D, Roscioli T, Kamsteeg E-J, van den Elzen C, van Beusekom E, Blaser S, Babul-Hirji R, Halliday W, Wright GJ, Stemple DL, Lin Y-Y, Lefeber DJ, van Bokhoven H. Missense mutations in β-1,3-N-acetylglucosaminyltransferase 1 (B3GNT1) cause Walker-Warburg syndrome. Hum Mol Genet. 2013;[Epub ahead of print] doi:10.1093/hmg/ddt021 .

Mutations in the satellite cell gene MEGF10 cause a recessive congenital myopathy with minicores

Authors:
Boyden SE, Mahoney LJ, Kawahara G, Myers JA, Mitsuhashi S, Estrella EA, Duncan AR, Dey F, Dechene ET, Blasko-Goehringer JM, Bönnemann CG, Darras BT, Mendell JR, Lidov HG, Nishino I, Beggs AH, Kunkel LM, Kang PB
Citation:
Neurogenetics. 2012 May;13(2):115-24. Epub 2012 Feb 28.
Epub:
Not Epub
Abstract:
We ascertained a nuclear family in which three of four siblings were affected with an unclassified autosomal recessive myopathy...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boyden SE, Mahoney LJ, Kawahara G, Myers JA, Mitsuhashi S, Estrella EA, Duncan AR, Dey F, Dechene ET, Blasko-Goehringer JM, Bönnemann CG, Darras BT, Mendell JR, Lidov HG, Nishino I, Beggs AH, Kunkel LM, Kang PB. Mutations in the satellite cell gene MEGF10 cause a recessive congenital myopathy with minicores. Neurogenetics. 2012 May;13(2):115-24. Epub 2012 Feb 28..

N-cadherin regulates primary motor axons growth and branching during zebrafish embryonic development

Authors:
Brusés JL
Citation:
J Comp Neurol. 2011 Feb 11. doi: 10.1002/cne.22602. [Epub ahead of print]
Epub:
Not Epub
Abstract:
N-cadherin is a classical type I cadherin that contributes to the formation of neural circuits by regulating growth cone...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brusés JL. N-cadherin regulates primary motor axons growth and branching during zebrafish embryonic development. J Comp Neurol. 2011 Feb 11. doi: 10.1002/cne.22602. [Epub ahead of print].

NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality

Authors:
Brothers KM, Gratacap RL, Barker SE, Newman ZR, Norum A, Wheeler RT
Citation:
PLoS Pathog. 2013;9(10):e1003634. doi:10.1371/journal.ppat.1003634
Epub:
Not Epub
Abstract:
Candida albicans is a human commensal and clinically important fungal pathogen that grows as both yeast and hyphal forms during...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brothers KM, Gratacap RL, Barker SE, Newman ZR, Norum A, Wheeler RT. NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality. PLoS Pathog. 2013;9(10):e1003634. doi:10.1371/journal.ppat.1003634.

Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin

Authors:
Boyden ED, Dietrich WF
Citation:
Nat Genet. 2006 Feb;38(2):240-4. Epub 2006 Jan 22
Epub:
Not Epub
Abstract:
The pathogenesis of Bacillus anthracis, the bacterium that causes anthrax, depends on secretion of three factors that combine...
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: mouse macrophages
Citation Extract:
Boyden ED, Dietrich WF. Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin. Nat Genet. 2006 Feb;38(2):240-4. Epub 2006 Jan 22.

Nanog regulates proliferation during early fish development

Authors:
Camp E, Sánchez-Sánchez AV, García-España A, Desalle R, Odqvist L, O'Connor JE, Mullor JL
Citation:
Stem Cells. 2009 Sep;27(9):2081-91
Epub:
Not Epub
Abstract:
Nanog is involved in controlling pluripotency and differentiation of stem cells in vitro. However, its function in vivo has...
Delivery Method:
Microinjection
Organism or Cell Type:
medaka embryos
Citation Extract:
Camp E, Sánchez-Sánchez AV, García-España A, Desalle R, Odqvist L, O'Connor JE, Mullor JL. Nanog regulates proliferation during early fish development. Stem Cells. 2009 Sep;27(9):2081-91.

Neurologic and ocular phenotype in Pitt-Hopkins syndrome and a zebrafish model

Authors:
Brockschmidt A, Filippi A, Charbel Issa P, Nelles M, Urbach H, Eter N, Driever W, Weber RG
Citation:
Hum Genet. 2011 May 5. [Epub ahead of print]
Epub:
Not Epub
Abstract:
In this study, we performed an in-depth analysis of the neurologic and ophthalmologic phenotype in a patient with Pitt-Hopkins...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brockschmidt A, Filippi A, Charbel Issa P, Nelles M, Urbach H, Eter N, Driever W, Weber RG. Neurologic and ocular phenotype in Pitt-Hopkins syndrome and a zebrafish model. Hum Genet. 2011 May 5. [Epub ahead of print].

Nitric oxide synthase regulates morphogenesis of zebrafish spinal cord motoneurons

Authors:
Bradley S, Tossell K, Lockley R, McDearmid JR
Citation:
J Neurosci. 2010 Dec 15;30(50):16818-31
Epub:
Not Epub
Abstract:
Nitric oxide (NO) is a signaling molecule that is synthesized in a range of tissues by the NO synthases (NOSs). In the immature...
Organism or Cell Type:
zebrafish
Citation Extract:
Bradley S, Tossell K, Lockley R, McDearmid JR. Nitric oxide synthase regulates morphogenesis of zebrafish spinal cord motoneurons. J Neurosci. 2010 Dec 15;30(50):16818-31.

Nitrogen excretion in developing zebrafish (Danio rerio): A role for Rh proteins and urea transporters

Authors:
Braun MH, Steele SL, Ekker M, Perry SF
Citation:
Am J Physiol Renal Physiol. 2009 Mar 11. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Injection of antisense oligonucleotide morpholinos to elicit selective gene knockdown of ammonia (Rhag, Rhbg and Rhcg1) or urea...
Organism or Cell Type:
zebrafish
Citation Extract:
Braun MH, Steele SL, Ekker M, Perry SF. Nitrogen excretion in developing zebrafish (Danio rerio): A role for Rh proteins and urea transporters. Am J Physiol Renal Physiol. 2009 Mar 11. [Epub ahead of print].

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