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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12245 scientific papers returned from the database with the search filters currently being used below.

A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence

Authors:
Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ, Mayhall EA, Amsterdam AH, Zon LI
Citation:
Blood. 2009 Mar 30. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Defining the genetic pathways essential for hematopoietic stem cell (HSC) development remains a fundamental goal impacting stem...
Organism or Cell Type:
zebrafish
Citation Extract:
Burns CE, Galloway JL, Smith AC, Keefe MD, Cashman TJ, Paik EJ, Mayhall EA, Amsterdam AH, Zon LI. A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 2009 Mar 30. [Epub ahead of print].

A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair

Authors:
Bruns AF, Yuldasheva N, Latham AM, Bao L, Pellet-Many C, Frankel P, Stephen SL, Howell GJ, Wheatcroft SB, Kearney MT, Zachary IC, Ponnambalam S
Citation:
PLoS ONE. 2012;7(11):e48539. doi:10.1371/journal.pone.0048539
Epub:
Not Epub
Abstract:
Vascular endothelial growth factor A (VEGF-A) binds to the VEGFR2 receptor tyrosine kinase, regulating endothelial function,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bruns AF, Yuldasheva N, Latham AM, Bao L, Pellet-Many C, Frankel P, Stephen SL, Howell GJ, Wheatcroft SB, Kearney MT, Zachary IC, Ponnambalam S. A Heat-Shock Protein Axis Regulates VEGFR2 Proteolysis, Blood Vessel Development and Repair. PLoS ONE. 2012;7(11):e48539. doi:10.1371/journal.pone.0048539.

A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development.

Authors:
Brott BK, Sokol SY.
Citation:
Dev Cell. 2005 May;8(5):703-15.
Epub:
Not Epub
Abstract:
Early stages of vertebrate heart development have been linked to Wnt signaling. Here we show in both gain- and loss-of-function...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Brott BK, Sokol SY.. A vertebrate homolog of the cell cycle regulator Dbf4 is an inhibitor of Wnt signaling required for heart development.. Dev Cell. 2005 May;8(5):703-15..

A zebrafish vasa morphant abolishes Vasa protein but does not affect the establishment of the germline

Authors:
Braat AK, van De Water S, Korving J, Zivkovic D.
Citation:
Genesis. 2001 Jul;30(3):183-5
Epub:
Not Epub
Abstract:
No abstract available.
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Braat AK, van De Water S, Korving J, Zivkovic D.. A zebrafish vasa morphant abolishes Vasa protein but does not affect the establishment of the germline. Genesis. 2001 Jul;30(3):183-5.

Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models

Authors:
Burrer R, Neuman BW, Ting JPC, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ
Citation:
J. Virol. 2007 Jun;81(11):5637-48. Epub 2007 Mar 7.
Epub:
Not Epub
Abstract:
The recent emergence of novel pathogenic human and animal coronaviruses has highlighted the need for antiviral therapies that...
Delivery Method:
peptide-coupled
Organism or Cell Type:
Mice, C57B16
Citation Extract:
Burrer R, Neuman BW, Ting JPC, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ. Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models. J. Virol. 2007 Jun;81(11):5637-48. Epub 2007 Mar 7..

Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling

Authors:
Bussmann J, Wolfe SA, Siekmann AF
Citation:
Development. 2011 May;138(9):1717-26. Epub 2011 Mar 23
Epub:
Not Epub
Abstract:
During angiogenic sprouting, newly forming blood vessels need to connect to the existing vasculature in order to establish a...
Organism or Cell Type:
zebrafish
Citation Extract:
Bussmann J, Wolfe SA, Siekmann AF. Arterial-venous network formation during brain vascularization involves hemodynamic regulation of chemokine signaling. Development. 2011 May;138(9):1717-26. Epub 2011 Mar 23.

Balancing cell numbers during organogenesis: Six1a differentially affects neurons and sensory hair cells in the inner ear

Authors:
Bricaud O, Collazo A
Citation:
Dev Biol. 2011 Sep 1;357(1):191-201. Epub 2011 Jul 2
Epub:
Not Epub
Abstract:
While genes involved in the differentiation of the mechanosensory hair cells and the neurons innervating them have been...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bricaud O, Collazo A. Balancing cell numbers during organogenesis: Six1a differentially affects neurons and sensory hair cells in the inner ear. Dev Biol. 2011 Sep 1;357(1):191-201. Epub 2011 Jul 2.

beta-Arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo

Authors:
Bryja V, Gradl D, Schambony A, Arenas E, Schulte G
Citation:
Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6690-5. Epub 2007 Apr 10.
Epub:
Not Epub
Abstract:
The Wnt/beta-catenin signaling pathway is crucial for proper embryonic development and tissue homeostasis. The phosphoprotein...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bryja V, Gradl D, Schambony A, Arenas E, Schulte G. beta-Arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proc Natl Acad Sci U S A. 2007 Apr 17;104(16):6690-5. Epub 2007 Apr 10..

ccdc80-l1 Is Involved in Axon Pathfinding of Zebrafish Motoneurons

Authors:
Brusegan C, Pistocchi A, Frassine A, Della Noce I, Schepis F, Cotelli F
Citation:
PLoS ONE. 2012;7(2):e31851. doi:10.1371/journal.pone.0031851
Epub:
Not Epub
Abstract:
Axon pathfinding is a subfield of neural development by which neurons send out axons to reach the correct targets. In...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Brusegan C, Pistocchi A, Frassine A, Della Noce I, Schepis F, Cotelli F. ccdc80-l1 Is Involved in Axon Pathfinding of Zebrafish Motoneurons. PLoS ONE. 2012;7(2):e31851. doi:10.1371/journal.pone.0031851.

Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in zebrafish

Authors:
Cai AQ, Radtke K, Linville A, Lander AD, Nie Q, Schilling TF
Citation:
Development. 2012 Jun;139(12):2150-5
Epub:
Not Epub
Abstract:
The vitamin A derivative retinoic acid (RA) is a morphogen that patterns the anterior-posterior axis of the vertebrate...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Cai AQ, Radtke K, Linville A, Lander AD, Nie Q, Schilling TF. Cellular retinoic acid-binding proteins are essential for hindbrain patterning and signal robustness in zebrafish. Development. 2012 Jun;139(12):2150-5.

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