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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12067 scientific papers returned from the database with the search filters currently being used below.

Midline crossing is not required for subsequent pathfinding decisions in commissural neurons

Authors:
Bonner J, Letko M, Nikolaus OB, Krug mL, Cooper A, Chadwick B, Conklin P, Lim A, Chien CB, Dorsky RI
Citation:
Neural Dev. 2012;7:18 doi:10.1186/1749-8104-7-18
Epub:
Not Epub
Abstract:
Growth cone navigation across the vertebrate midline is critical in the establishment of nervous system connectivity. While...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bonner J, Letko M, Nikolaus OB, Krug mL, Cooper A, Chadwick B, Conklin P, Lim A, Chien CB, Dorsky RI. Midline crossing is not required for subsequent pathfinding decisions in commissural neurons. Neural Dev. 2012;7:18 doi:10.1186/1749-8104-7-18.

miR-27b controls venous specification and tip cell fate

Authors:
Biyashev D, Veliceasa D, Topczewski J, Topczewska JM, Mizgirev I, Vinokour E, Reddi AL, Licht JD, Revskoy SY, Volpert OV
Citation:
Blood. 2012 Mar 15;119(11):2679-87. doi: 10.1182/blood-2011-07-370635. Epub 2011 Dec 29
Epub:
Not Epub
Abstract:
We discovered that miR-27b controls 2 critical vascular functions: it turns the angiogenic switch on by promoting endothelial...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Biyashev D, Veliceasa D, Topczewski J, Topczewska JM, Mizgirev I, Vinokour E, Reddi AL, Licht JD, Revskoy SY, Volpert OV. miR-27b controls venous specification and tip cell fate. Blood. 2012 Mar 15;119(11):2679-87. doi: 10.1182/blood-2011-07-370635. Epub 2011 Dec 29.

Molecular cloning, gene expression in albino mutants and gene knockdown studies of tyrosinase mRNA in rainbow trout

Authors:
Boonanuntanasarn S, Yoshizaki G, Iwai K, Takeuchi T
Citation:
Pigment Cell Res. 2004 Aug;17(4):413-21
Epub:
Not Epub
Abstract:
Tyrosinase has a role in melanin synthesis and several defects of the tyrosinase gene lead to albinism. Here, we cloned and...
Delivery Method:
Microinjection
Organism or Cell Type:
trout, rainbow
Citation Extract:
Boonanuntanasarn S, Yoshizaki G, Iwai K, Takeuchi T. Molecular cloning, gene expression in albino mutants and gene knockdown studies of tyrosinase mRNA in rainbow trout. Pigment Cell Res. 2004 Aug;17(4):413-21.

Morpholino Studies in Xenopus Brain Development

Authors:
Bestman JE, Cline HT
Citation:
Methods Molec Biol. 2013;(1082)2014:155-71. doi:10.1007/978-1-62703-655-9_11
Epub:
Not Epub
Abstract:
Antisense morpholino oligonucleotides (MOs) have become a valuable method to knock down protein levels, to block mRNA splicing...
Organism or Cell Type:
X.laevis & X.tropicalis
Citation Extract:
Bestman JE, Cline HT. Morpholino Studies in Xenopus Brain Development. Methods Molec Biol. 2013;(1082)2014:155-71. doi:10.1007/978-1-62703-655-9_11.

Multiple mechanisms mediate motor neuron migration in the zebrafish hindbrain

Authors:
Bingham SM, Sittaramane V, Mapp O, Patil S, Prince VE, Chandrasekhar A
Citation:
Dev Neurobiol. 2009 Nov 23. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The transmembrane protein Van gogh-like 2 (Vangl2) is a component of the noncanonical Wnt/Planar Cell Polarity (PCP) signaling...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bingham SM, Sittaramane V, Mapp O, Patil S, Prince VE, Chandrasekhar A. Multiple mechanisms mediate motor neuron migration in the zebrafish hindbrain. Dev Neurobiol. 2009 Nov 23. [Epub ahead of print].

Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1

Authors:
Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Guran T, Kayserili H, Hamamy H, Reversade B
Citation:
Nat Genet. 2012;[Epub ahead of print] doi:10.1038/ng.2259 N1
Epub:
Not Epub
Abstract:
Using homozygosity mapping and locus resequencing, we found that alterations in the homeodomain of the IRX5 transcription...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Bonnard C, Strobl AC, Shboul M, Lee H, Merriman B, Nelson SF, Ababneh OH, Uz E, Guran T, Kayserili H, Hamamy H, Reversade B. Mutations in IRX5 impair craniofacial development and germ cell migration via SDF1. Nat Genet. 2012;[Epub ahead of print] doi:10.1038/ng.2259 N1 .

Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome

Authors:
Bicknell LS, Walker S, Klingseisen A, Stiff T, Leitch A, Kerzendorfer C, Martin CA, Yeyati P, Al Sanna N, Bober M, Johnson D, Wise C, Jackson AP, O'Driscoll M, Jeggo PA
Citation:
Nat Genet. 2011 Feb 27;43(4):350-5. doi: 10.1038/ng.776
Epub:
Not Epub
Abstract:
Studies into disorders of extreme growth failure (for example, Seckel syndrome and Majewski osteodysplastic primordial dwarfism...
Organism or Cell Type:
zebrafish
Citation Extract:
Bicknell LS, Walker S, Klingseisen A, Stiff T, Leitch A, Kerzendorfer C, Martin CA, Yeyati P, Al Sanna N, Bober M, Johnson D, Wise C, Jackson AP, O'Driscoll M, Jeggo PA. Mutations in ORC1, encoding the largest subunit of the origin recognition complex, cause microcephalic primordial dwarfism resembling Meier-Gorlin syndrome. Nat Genet. 2011 Feb 27;43(4):350-5. doi: 10.1038/ng.776.

NBP, a zebrafish homolog of human Kank3, is a novel Numb interactor essential for epidermal integrity and neurulation

Authors:
Boggetti B, Jasik J, Takamiya M, Strähle U, Reugels AM, Campos-Ortega JA
Citation:
Dev Biol. 2012 Feb 22. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Numb is an adaptor protein implicated in diverse basic cellular processes. Using the yeast-two hybrid system we isolated a...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Boggetti B, Jasik J, Takamiya M, Strähle U, Reugels AM, Campos-Ortega JA. NBP, a zebrafish homolog of human Kank3, is a novel Numb interactor essential for epidermal integrity and neurulation. Dev Biol. 2012 Feb 22. [Epub ahead of print].

Neural protein Olig2 acts upstream of the transcriptional regulator sim1 to specify diencephalic dopaminergic neurons

Authors:
Borodovsky N, Ponomaryov T, Frenkel S, Levkowitz G
Citation:
Dev Dyn. 2009 Feb 27. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Neural factors are expressed in neural progenitors and regulate neurogenesis and gliogenesis. Recent studies suggested that...
Organism or Cell Type:
zebrafish
Citation Extract:
Borodovsky N, Ponomaryov T, Frenkel S, Levkowitz G. Neural protein Olig2 acts upstream of the transcriptional regulator sim1 to specify diencephalic dopaminergic neurons. Dev Dyn. 2009 Feb 27. [Epub ahead of print].

Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors

Authors:
Bertrand V, Hudson C, Caillol D, Popovici C, Lemaire P
Citation:
Cell. 2003 Nov 26;115(5):615-27
Epub:
Not Epub
Abstract:
In chordates, formation of neural tissue from ectodermal cells requires an induction. The molecular nature of the inducer...
Delivery Method:
Microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Bertrand V, Hudson C, Caillol D, Popovici C, Lemaire P. Neural tissue in ascidian embryos is induced by FGF9/16/20, acting via a combination of maternal GATA and Ets transcription factors. Cell. 2003 Nov 26;115(5):615-27.

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