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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development
Citation:
J Cell Biol. 2019;]Epub ahead of print] doi:10.1083/jcb.201901032 Epub:
Yes Abstract:
Trogocytosis, in which cells nibble away parts of neighboring cells, is an intercellular cannibalism process conserved from... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Gong J, Gaitanos TN, Luu O, Huang Y, Gaitanos L, Lindner J, Winklbauer R, Rüdiger Klein R. Gulp1 controls Eph/ephrin trogocytosis and is important for cell rearrangements during development. J Cell Biol. 2019;]Epub ahead of print] doi:10.1083/jcb.201901032. |
In Vitro Validation of Phosphorodiamidate Morpholino Oligomers
Citation:
Molecules. 2019;24(6):2922 doi:0.3390/molecules24162922 Epub:
Not Epub Abstract:
One of the crucial aspects of screening antisense oligonucleotides destined for therapeutic application is confidence that the... Delivery Method:
electroporation Lipofectin Lipofectamine Endo-Porter Organism or Cell Type:
cell culture: human dermal fibroblasts, human myoblasts Citation Extract: Aung-Htut MT, McIntosh CS, West KA, Fletcher S, Wilton SD. In Vitro Validation of Phosphorodiamidate Morpholino Oligomers. Molecules. 2019;24(6):2922 doi:0.3390/molecules24162922. |
U1 snRNP regulates cancer cell migration and invasion
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/730515 Epub:
Not Epub Abstract:
Stimulated cells and cancer cells have widespread shortening of mRNA 3′-utranslated regions (3′UTRs) and switches to shorter... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa, A549, MCF-7 and MB-231 Citation Extract: Oh J-M, Venters CC, Di C, Pinto AM, Wan L, Younis I, Cai Z, Arai C, So BR, Dreyfuss G. U1 snRNP regulates cancer cell migration and invasion. bioRxiv. 2019;[preprint] doi:10.1101/730515 . |
De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies
Citation:
Am J Hum Genet. 2019;[Epub ahead of print] doi:10.1016/j.ajhg.2019.07.005 Epub:
Yes Abstract:
The identification of genetic variants implicated in human developmental disorders has been revolutionized by second-generation... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Holt RJ, Young RM, Crespo B, Ceroni F, Curry CJ, Bellacchio E, Bax DA, Ciolfi A, Simon M, Fagerberg CR, van Binsbergen E, De Luca A, Memo L, Dobyns WB, Mohammed AA, Clokie SJH, Seco CZ, Jiang Y-H, Sørensen KP, Andersen H, Sullivan J, Powis Z, Chassevent A, Smith-Hicks C, Petrovski S, Antoniadi T, Shashi V, Gelb BD, Wilson SW, Gerrelli D, Tartaglia M, Chassaing N, Calvas P, Ragge NK. De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies. Am J Hum Genet. 2019;[Epub ahead of print] doi:10.1016/j.ajhg.2019.07.005. |
Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium
Citation:
Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2 Epub:
Not Epub Abstract:
Haematopoietic stem cells are generated from the haemogenic endothelium (HE) located in the floor of the dorsal aorta (DA).... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Bonkhofer F, Rispoli R, Pinheiro P, Krecsmarik M, Schneider-Swales J, Tsang IHC, de Bruijn M, Monteiro R, Peterkin T, Patient R. Blood stem cell-forming haemogenic endothelium in zebrafish derives from arterial endothelium. Nat Comm. 2019;10(1):3577. doi:10.1038/s41467-019-11423-2. |
TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes
Citation:
J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253 Epub:
Yes Abstract:
Cleavage of influenza virus hemagglutinin (HA) by host cell proteases is essential for virus infectivity and spread. We... Delivery Method:
peptide-linked Organism or Cell Type:
cell culture: primary human bronchial epithelial cells (HBEC), primary type II alveolar epithelial cells (AECII) and Calu-3 cells Citation Extract: Limburg H, Harbig A, Bestle D, Stein DA, Moulton HM, Jaeger J, Janga H, Hardes K, Koepke J, Schulte L, Koczulla AR, Schmeck B, Klenk HD, Böttcher-Friebertshäuser E. TMPRSS2 is the major activating protease of influenza A virus in primary human airway cells and influenza B virus in human type II pneumocytes. J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. PMID: 31391268; PMCID: PMC6803253. |
Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly
Citation:
Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24 Epub:
Not Epub Abstract:
Epiboly, the first morphogenetic cell movement that occurs in the zebrafish embryo, is the process by which the blastoderm... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lepage SE, Tada M, Bruce AE. Zebrafish Dynamin is required for maintenance of enveloping layer integrity and the progression of epiboly. Dev Biol. 2014 Jan 1;385(1):52-66. doi: 10.1016/j.ydbio.2013.10.015. Epub 2013 Oct 24. |
Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/693853 Epub:
Not Epub Abstract:
The CRISPR/Cas9 technology has been widely utilized for knocking out genes involved in various biological processes in... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Zhang F, Li X, He M, Ye D, Xiong F, Amin G, Zhu Z, Sun Y. Efficient generation of zebrafish maternal-zygotic mutants through transplantation of ectopically induced and Cas9/gRNA targeted PGCs. bioRxiv. 2019:[preprint] doi:10.1101/693853 . |
Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/712216 Epub:
Not Epub Abstract:
Developmental gene regulatory networks (GRNs) describe the interactions among gene products that drive the differential... Delivery Method:
microinjection Organism or Cell Type:
Heliocidaris erythrogramma (sea urchin) Citation Extract: Edgar A, Byrnev M, McClay DR, Wray GA. Evolution of abbreviated development in Heliocidaris erythrogramma dramatically re-wired the highly conserved sea urchin developmental gene regulatory network to decouple signaling center function from ultimate fate. bioRxiv. 2019:[preprint] doi:10.1101/712216. |
Gclc deletion in surface-ectoderm tissues induces microphthalmia
Citation:
bioRxiv. 2019:[preprint]. doi:10.1101/700591 Epub:
Not Epub Abstract:
Glutamate cysteine ligase catalytic subunit (Gclc) is the catalytic subunit for the glutamate-cysteine ligase (Gcl) enzyme. Gcl... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Thompson B, Chen Y, Philippe J, Anderson D, Golla JP, Davidson E, Apostolopoulos N, Schey K, Katsanis N, Orlicky DJ, Thompson D, Vasiliou V. Gclc deletion in surface-ectoderm tissues induces microphthalmia. bioRxiv. 2019:[preprint]. doi:10.1101/700591. |