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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Genetic and functional evidence relates a missense variant in B4GALT1 to lower LDL-C and fibrinogen

Authors:
Montasser ME, Van Hout CV, McFarland R, Rosenberg A, Callaway M, Shen B, Li N, Daly TJ, Howard AD, Lin W, Mao Y, Ye B, Gatta GD, Tzoneva G, Perry J, Ryan KA, Miloscio L, Economides AN, Regeneron Genetics Center, NHLBI TOPMed Program, Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten E, Zaghloul NA, Taylor SI, O’Connell JR, Shuldiner AR
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/721704
Epub:
Not Epub
Abstract:
Increased LDL-cholesterol (LDL-C) and fibrinogen are independent risk factors for cardiovascular disease (CVD). We identified...
Link:
https://www.biorxiv.org/content/10.1101/721704v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Montasser ME, Van Hout CV, McFarland R, Rosenberg A, Callaway M, Shen B, Li N, Daly TJ, Howard AD, Lin W, Mao Y, Ye B, Gatta GD, Tzoneva G, Perry J, Ryan KA, Miloscio L, Economides AN, Regeneron Genetics Center, NHLBI TOPMed Program, Sztalryd-Woodle C, Mitchell BD, Healy M, Streeten E, Zaghloul NA, Taylor SI, O’Connell JR, Shuldiner AR. Genetic and functional evidence relates a missense variant in B4GALT1 to lower LDL-C and fibrinogen. bioRxiv. 2019;[preprint] doi:10.1101/721704.

A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus

Authors:
Li J, Perfetto M, Materna C, Li R, Thi Tran H, Vleminckx K, Duncan MK, Wei S
Citation:
Sci Rep. 2019 Aug 1;9(1):11191. doi: 10.1038/s41598-019-47665-9
Epub:
Not Epub
Abstract:
During vertebrate embryogenesis, the cranial neural crest (CNC) forms at the neural plate border and subsequently migrates and...
Link:
https://www.nature.com/articles/s41598-019-47665-9
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Li J, Perfetto M, Materna C, Li R, Thi Tran H, Vleminckx K, Duncan MK, Wei S. A new transgenic reporter line reveals Wnt-dependent Snai2 re-expression and cranial neural crest differentiation in Xenopus. Sci Rep. 2019 Aug 1;9(1):11191. doi: 10.1038/s41598-019-47665-9.

LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis.

Authors:
Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefańczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J
Citation:
Blood. 2019 Jul 31. pii: blood 2019000095. doi: 10.1182/blood.2019000095. [Epub ahead of print]
Epub:
Yes
Abstract:
LMO2 (hematopoietic transcription factor LIM domain only 2), a member of the TAL1 transcriptional complex, plays an essential...
Link:
http://www.bloodjournal.org/content/early/2019/07/31/blood.2019000095
Organism or Cell Type:
zebrafish
Citation Extract:
Morishima T, Krahl AC, Nasri M, Xu Y, Aghaallaei N, Findik B, Klimiankou M, Ritter M, Hartmann MD, Gloeckner CJ, Stefańczyk S, Lindner C, Oswald B, Bernhard R, Hähnel K, Hermanutz-Klein U, Ebinger M, Handgretinger R, Casadei N, Welte K, Andre M, Müller P, Bajoghli B, Skokowa J. LMO2 activation by deacetylation is indispensable for hematopoiesis and T-ALL leukemogenesis. . Blood. 2019 Jul 31. pii: blood 2019000095. doi: 10.1182/blood.2019000095. [Epub ahead of print].

Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons

Authors:
Seifinejad A, Li S, Mikhail C, Vassalli A, Pradervand S, Arribat Y, Pezeshgi Modarres H, Allen B, John RM, Amati F, Tafti M
Citation:
Proc Natl Acad Sci U S A. 2019 Aug 2. pii: 201902148. doi: 10.1073/pnas.1902148116. [Epub ahead of print]
Epub:
Yes
Abstract:
Hypocretin/orexin (HCRT) and melanin concentrating hormone (MCH) neuropeptides are exclusively produced by the lateral...
Link:
https://www.pnas.org/content/early/2019/08/01/1902148116
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Seifinejad A, Li S, Mikhail C, Vassalli A, Pradervand S, Arribat Y, Pezeshgi Modarres H, Allen B, John RM, Amati F, Tafti M. Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons. Proc Natl Acad Sci U S A. 2019 Aug 2. pii: 201902148. doi: 10.1073/pnas.1902148116. [Epub ahead of print].

Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation

Authors:
Jiang D, Jiang Z, Lu D, Wang X, Liang H, Zhang J, Meng Y, Li Y, Wu D, Huang Y, Chen Y, Deng H, Wu Q, Xiong J, Meng A, Yu L
Citation:
Nat Cell Biol. 2019 Aug;21(8):966-977. doi: 10.1038/s41556-019-0358-6. Epub 2019 Aug 1
Epub:
Not Epub
Abstract:
Migrasomes are recently identified vesicular organelles that form on retraction fibres behind migrating cells. Whether...
Link:
https://www.nature.com/articles/s41556-019-0358-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Jiang D, Jiang Z, Lu D, Wang X, Liang H, Zhang J, Meng Y, Li Y, Wu D, Huang Y, Chen Y, Deng H, Wu Q, Xiong J, Meng A, Yu L. Migrasomes provide regional cues for organ morphogenesis during zebrafish gastrulation. Nat Cell Biol. 2019 Aug;21(8):966-977. doi: 10.1038/s41556-019-0358-6. Epub 2019 Aug 1.

Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants

Authors:
Santos JMA, Mendes-Silva L, Afonso V, Martins G, Machado RSR, Lopes JA, Cancela L, Futschik ME, Sachinidis A, Gavaia P, Bragança J
Citation:
Cell Death Dis. 2019 Aug 5;10(8):582. doi: 10.1038/s41419-019-1816-6
Epub:
Not Epub
Abstract:
Mutations and inadequate methylation profiles of CITED2 are associated with human congenital heart disease (CHD). In mouse,...
Link:
https://www.nature.com/articles/s41419-019-1816-6
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Santos JMA, Mendes-Silva L, Afonso V, Martins G, Machado RSR, Lopes JA, Cancela L, Futschik ME, Sachinidis A, Gavaia P, Bragança J. Exogenous WNT5A and WNT11 proteins rescue CITED2 dysfunction in mouse embryonic stem cells and zebrafish morphants. Cell Death Dis. 2019 Aug 5;10(8):582. doi: 10.1038/s41419-019-1816-6.

Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia

Authors:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/719666
Epub:
Not Epub
Abstract:
Neural crest migration requires cells to move through an environment filled with dense extracellular matrix and mesoderm to...
Link:
https://www.biorxiv.org/content/10.1101/719666v1
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
McLennan R, McKinney MC, Teddy JM, Morrison JA, Kasemeier-Kulesa JC, Ridenour DA, Manthe CA, Giniunaite R, Robinson M, Baker RE, Maini PK, Kulesa PM. Neural crest cells bulldoze through the microenvironment using Aquaporin-1 to stabilize filopodia. bioRxiv. 2019:[preprint] doi:10.1101/719666.

Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence

Authors:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S
Citation:
BioRxiv. 2019:[preprint] doi:10.1101/719781
Epub:
Not Epub
Abstract:
Shigella flexneri is historically regarded as the primary agent of bacillary dysentery, yet the closely-related Shigella sonnei...
Link:
https://www.biorxiv.org/content/10.1101/719781v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Torraca V, Kaforou M, Watson J, Duggan GM, Guerrero-Gutierrez H, Krokowski S, Hollinshead M, Thomas B. Clarke TB, Mostowy RJ, Tomlinson GS, Sancho-Shimizu V, Clements A, Mostowy S. Shigella sonnei infection of zebrafish reveals that O-antigen mediates neutrophil tolerance and dysentery incidence. BioRxiv. 2019:[preprint] doi:10.1101/719781.

Early expression of Tubulin Beta-III in avian cranial neural crest cells

Authors:
Chacon J, Rogers CD
Citation:
Gene Expr Patt. 2019;[Epub ahead of print] doi:10.1016/j.gep.2019.119067
Epub:
Yes
Abstract:
Neural crest cells are a transient stem-like cell population that forms in the dorsal neural tube of vertebrate embryos and...
Link:
https://www.sciencedirect.com/science/article/abs/pii/S1567133X19300675
Delivery Method:
electroporation
Organism or Cell Type:
Gallus gallus (chick)
Citation Extract:
Chacon J, Rogers CD. Early expression of Tubulin Beta-III in avian cranial neural crest cells. Gene Expr Patt. 2019;[Epub ahead of print] doi:10.1016/j.gep.2019.119067.

THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis

Authors:
Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/719823
Epub:
Not Epub
Abstract:
Apoptosis of cochlear hair cells is a key step towards age-related hearing loss. Although numerous genes have been implicated...
Link:
https://www.biorxiv.org/content/10.1101/719823v1
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang L, Gao Y, Zhang R, Sun F, Cheng C, Qian F, Duan X, Wei G, Pang X, Chen P, Chai R, Yang T, Wu H, Liu D. THOC1 deficiency leads to late-onset nonsyndromic hearing loss through p53-mediated hair cell apoptosis. bioRxiv. 2019;[preprint] doi:10.1101/719823 .

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