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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis

Authors:
Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK
Citation:
PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698
Epub:
Not Epub
Abstract:
Kidneys are composed of numerous ciliated epithelial tubules called nephrons. Each nephron functions to reabsorb nutrients and...
Link:
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0221698
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Corkins ME, Krneta-Stankic V, Kloc M, McCrea PD, Gladden AB, Miller RK. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14(8):e0221698. doi:10.1371/journal.pone.0221698.

ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients

Authors:
Xie Y, Gao L, Xu C, Chu L, Gao L, Wu R, Liu Y, Liu T, Sun XJ, Ren R, Tang J, Zheng Y, Zhou Y, Shen S
Citation:
Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print]
Epub:
Yes
Abstract:
Hematopoiesis is a finely regulated process in vertebrates under both homeostatic and stress conditions. By whole exome...
Link:
http://www.haematologica.org/content/early/2019/08/26/haematol.2018.210286.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie Y, Gao L, Xu C, Chu L, Gao L, Wu R, Liu Y, Liu T, Sun XJ, Ren R, Tang J, Zheng Y, Zhou Y, Shen S. ARHGEF12 regulates erythropoiesis and is involved in erythroid regeneration after chemotherapy in acute lymphoblastic leukemia patients. Haematologica. 2019 Aug 29. pii: haematol.2018.210286. doi: 10.3324/haematol.2018.210286. [Epub ahead of print].

Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1

Authors:
Ichikawa T, Stuckenholz C, Davidson LA
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750752
Epub:
Not Epub
Abstract:
Classical cadherins are well-known primary adhesion molecules responsible for physically connecting neighboring cells and...
Link:
https://www.biorxiv.org/content/10.1101/750752v1
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Ichikawa T, Stuckenholz C, Davidson LA. Non-junctional Cadherin3 regulates cell migration and contact inhibition of locomotion via domain-dependent opposing regulations of Rac1. bioRxiv. 2019;[preprint] doi:10.1101/750752.

Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion

Authors:
Lekszas C, Foresti O, Raote I, Daniel Lietdke D, Koenig E-M, Nanda I, Vona C, De Coster P, Cauwels R, Malhotra V, Haaf T
Citation:
bioRxiv. 2019;[preprint] doi:10.1101/750349
Epub:
Not Epub
Abstract:
The transport and Golgi organization 1 (TANGO1) family proteins have been shown to play pivotal roles in the secretory pathway...
Link:
https://www.biorxiv.org/content/10.1101/750349v1
Delivery Method:
FuGENE HD transfection reagent
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Lekszas C, Foresti O, Raote I, Daniel Lietdke D, Koenig E-M, Nanda I, Vona C, De Coster P, Cauwels R, Malhotra V, Haaf T. Biallelic TANGO1 mutations cause a novel syndromal disease due to hampered cellular collagen secretion. bioRxiv. 2019;[preprint] doi:10.1101/750349.

Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome

Authors:
Liu ZZ, Guo J, Lu Y, Liu W, Fu X, Yao T, Zhou Y, Xu HA
Citation:
Int J Exp Pathol. 2019 Aug 28. doi: 10.1111/iep.12331. [Epub ahead of print]
Epub:
Yes
Abstract:
CHARGE syndrome is a congenital disorder with multiple malformations in the craniofacial structures, and cardiovascular and...
Link:
https://onlinelibrary.wiley.com/doi/abs/10.1111/iep.12331
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Liu ZZ, Guo J, Lu Y, Liu W, Fu X, Yao T, Zhou Y, Xu HA. Sema3E is required for migration of cranial neural crest cells in zebrafish: Implications for the pathogenesis of CHARGE syndrome. Int J Exp Pathol. 2019 Aug 28. doi: 10.1111/iep.12331. [Epub ahead of print].

Genetic compensation by epob in pronephros development in epoa mutant zebrafish

Authors:
She J, Wu Y, Lou B, Lodd E, Klems A, Schmoehl F, Yuan Z, Noble FL, Kroll J
Citation:
Cell Cycle. 2019 Aug 26:1-14. doi: 10.1080/15384101.2019.1656019. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Zebrafish erythropoietin a (epoa) is a well characterized regulator of red blood cell formation. Recent morpholino mediated...
Link:
https://www.tandfonline.com/doi/full/10.1080/15384101.2019.1656019
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
She J, Wu Y, Lou B, Lodd E, Klems A, Schmoehl F, Yuan Z, Noble FL, Kroll J. Genetic compensation by epob in pronephros development in epoa mutant zebrafish. Cell Cycle. 2019 Aug 26:1-14. doi: 10.1080/15384101.2019.1656019. [Epub ahead of print].

Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain

Authors:
Bhattarai P, Cosacak MI, Mashkaryan V, Yilmaz S, Popova S, Govindarajan N, Brandt K, Zhang Y, Kizil C
Citation:
bioRxiv. 2019:[preprint] doi:10.1101/748970
Epub:
Not Epub
Abstract:
It was recently suggested that supplying the brain with new neurons could counteract Alzheimer's disease. This provocative...
Link:
https://www.biorxiv.org/content/10.1101/748970v1
Delivery Method:
i.c.v. intracerebroventricular injection
Organism or Cell Type:
zebrafish
Citation Extract:
Bhattarai P, Cosacak MI, Mashkaryan V, Yilmaz S, Popova S, Govindarajan N, Brandt K, Zhang Y, Kizil C. Neuron-glia interaction through Serotonin-BDNF-NGFR axis enables regenerative neurogenesis in Alzheimer's model of adult zebrafish brain. bioRxiv. 2019:[preprint] doi:10.1101/748970 .

Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi

Authors:
Negri A, Ferrari M, Nodari R, Coppa E, Mastrantonio V, Zanzani S, Porretta D, Bandi C, Urbanelli S, Epis S
Citation:
Malar J. 2019;18:294. doi:10.1186/s12936-019-2925-5
Epub:
Not Epub
Abstract:
Background: Insecticides are still at the core of insect pest and vector control programmes. Several lines of evidence indicate...
Link:
https://malariajournal.biomedcentral.com/articles/10.1186/s12936-019-2925-5
Delivery Method:
Vivo-Morpholino bathing
Organism or Cell Type:
Anopheles stephensi (mosquito)
Citation Extract:
Negri A, Ferrari M, Nodari R, Coppa E, Mastrantonio V, Zanzani S, Porretta D, Bandi C, Urbanelli S, Epis S. Gene silencing through RNAi and antisense Vivo-Morpholino increases the efficacy of pyrethroids on larvae of Anopheles stephensi. Malar J. 2019;18:294. doi:10.1186/s12936-019-2925-5.

A thrombomodulin-like gene is crucial to the collective migration of epibolic blastomeres during germ layer formation and organogenesis in zebrafish

Authors:
Lee G-H, Chang C-L, Chiu W-T, Hsiao T-S, Chen P-Y, Wang K-C, Kuo C-H, Chen B-H, Shi G-Y, Wu H-L, Fu T-F
Citation:
J Biomed Sci. 2019;26(1):60. doi:10.1186/s12929-019-0549-2
Epub:
Not Epub
Abstract:
Background: Thrombomodulin (TM), an integral membrane protein, has long been known for its anticoagulant activity. Recent...
Link:
https://jbiomedsci.biomedcentral.com/articles/10.1186/s12929-019-0549-2
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lee G-H, Chang C-L, Chiu W-T, Hsiao T-S, Chen P-Y, Wang K-C, Kuo C-H, Chen B-H, Shi G-Y, Wu H-L, Fu T-F. A thrombomodulin-like gene is crucial to the collective migration of epibolic blastomeres during germ layer formation and organogenesis in zebrafish. J Biomed Sci. 2019;26(1):60. doi:10.1186/s12929-019-0549-2.

Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis

Authors:
Wade SM, Ohnesorge N, McLoughlin H, Biniecka M, Carter SP, Trenkman M, Cunningham CC, McGarry T, Canavan M, Kennedy BN, Veale DJ, Fearon U
Citation:
EBioMedicine. 2019;[Epub ahead of print] doi:10.1016/j.ebiom.2019.08.043
Epub:
Yes
Abstract:
Background: Although neoangiogenesis is a hallmark of chronic inflammatory diseases such as inflammatory arthritis and many...
Link:
https://www.ebiomedicine.com/article/S2352-3964(19)30566-3/abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wade SM, Ohnesorge N, McLoughlin H, Biniecka M, Carter SP, Trenkman M, Cunningham CC, McGarry T, Canavan M, Kennedy BN, Veale DJ, Fearon U. Dysregulated miR-125a promotes angiogenesis through enhanced glycolysis. EBioMedicine. 2019;[Epub ahead of print] doi:10.1016/j.ebiom.2019.08.043.

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