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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
There are 12353 scientific papers returned from the database with the search filters currently being used below.
A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human
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Citation:
Nucl Acids Res. 2018;[Epub ahead of print] doi:10.1093/nar/gky166 Epub:
Yes Abstract:
Thousands of human disease-associated single nucleotide polymorphisms (SNPs) lie in the non-coding genome, but only a handful... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Madelaine R, Notwell JH, Skariah G, Halluin C, Chen CC, Bejerano G, Mourrain P. A screen for deeply conserved non-coding GWAS SNPs uncovers a MIR-9-2 functional mutation associated to retinal vasculature defects in human. Nucl Acids Res. 2018;[Epub ahead of print] doi:10.1093/nar/gky166. |
Sea urchin histamine receptor 1 regulates programmed cell death in larval Strongylocentrotus purpuratus
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Citation:
Sci Rep. 2018;8:4002 doi:10.1038/s41598-018-22397-4 Epub:
Not Epub Abstract:
Settlement is a rapid process in many marine invertebrate species, transitioning a planktonic larva into a benthic juvenile. In... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Strongylocentrotus purpuratus (sea urchin) Citation Extract: Lutek K, Dhaliwal RS, Van Raay TJ, Heyland A. Sea urchin histamine receptor 1 regulates programmed cell death in larval Strongylocentrotus purpuratus. Sci Rep. 2018;8:4002 doi:10.1038/s41598-018-22397-4. |
An interaction between myosin-10 and the cell cycle regulator Wee1 links spindle dynamics to mitotic progression in epithelia
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Citation:
J Cell Biol. 2018 Jan 10. pii: jcb.201708072. doi: 10.1083/jcb.201708072. [Epub ahead of print] Epub:
Yes Abstract:
Anaphase in epithelia typically does not ensue until after spindles have achieved a characteristic position and orientation,... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Sandquist JC, Larson ME, Woolner S, Ding Z, Bement WM. An interaction between myosin-10 and the cell cycle regulator Wee1 links spindle dynamics to mitotic progression in epithelia. J Cell Biol. 2018 Jan 10. pii: jcb.201708072. doi: 10.1083/jcb.201708072. [Epub ahead of print]. |
Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure
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Citation:
Invest Ophthalmol Vis Sci. 2018;59:1167-77. doi:10.1167/iovs.17-22827 Epub:
Not Epub Abstract:
Purpose: Coloboma is a sight-threatening congenital eye disease caused by a failure in optic fissure (OF) closure. The aim of... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Cao M, Ouyang J, Guo J, Lin S, Chen S. Metalloproteinase Adamts16 Is Required for Proper Closure of the Optic Fissure. Invest Ophthalmol Vis Sci. 2018;59:1167-77. doi:10.1167/iovs.17-22827 . |
Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders
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Citation:
Nature. 2018 Feb 1;554(7690):112-117. doi: 10.1038/nature25449. Epub 2018 Jan 24 Epub:
Not Epub Abstract:
Many craniofacial disorders are caused by heterozygous mutations in general regulators of housekeeping cellular functions such... Delivery Method:
microinjection Organism or Cell Type:
Xenopus, zebrafish Citation Extract: Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders. Nature. 2018 Feb 1;554(7690):112-117. doi: 10.1038/nature25449. Epub 2018 Jan 24. |
The transcription factor Dach1 is essential for podocyte function
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Citation:
J Cell Mol Med. 2018 Mar 2. doi: 10.1111/jcmm.13544. [Epub ahead of print] Epub:
Yes Abstract:
Dedifferentiation and loss of podocytes are the major cause of chronic kidney disease. Dach1, a transcription factor that is... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Endlich N, Kliewe F, Kindt F, Schmidt K, Kotb AM, Artelt N, Lindenmeyer MT, Cohen CD, Döring F, Kuss AW, Amann K, Moeller MJ, Kabgani N, Blumenthal A, Endlich K. The transcription factor Dach1 is essential for podocyte function. J Cell Mol Med. 2018 Mar 2. doi: 10.1111/jcmm.13544. [Epub ahead of print]. |
Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity
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Citation:
Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 26. pii: S0278-5846(17)30733-9. doi: 10.1016/j.pnpbp.2018.02.010. [Epub ahead of print] Epub:
Yes Abstract:
Polymorphisms in the gene coding for the adhesion G-protein coupled receptor LPHN3 are a risk factor for attention-deficit/... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Lange M, Froc C, Grunwald H, Norton WHJ, Bally-Cuif L. Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Feb 26. pii: S0278-5846(17)30733-9. doi: 10.1016/j.pnpbp.2018.02.010. [Epub ahead of print]. |
chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis
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Citation:
Dev Biol. 2005 Dec 15;288(2):348-62. Epub 2005 Nov 21 Epub:
Not Epub Abstract:
Despite the importance of the retinal pigment epithelium (RPE) for vision, the molecular processes involved in its... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Rojas-Muñoz A, Dahm R, Nüsslein-Volhard C. chokh/rx3 specifies the retinal pigment epithelium fate independently of eye morphogenesis. Dev Biol. 2005 Dec 15;288(2):348-62. Epub 2005 Nov 21. |
Morpholino oligomers tested in vitro, in biofilm and in vivo against multidrug-resistant Klebsiella pneumoniae
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Citation:
J Antimicrob Chemother. 2018;[Epub ahead of print] doi:10.1093/jac/dky058 Epub:
Yes Abstract:
Background: Klebsiella pneumoniae is an opportunistic pathogen and many strains are multidrug resistant. KPC is one of the most... Delivery Method:
peptide-linked Organism or Cell Type:
Klebsiella pneumoniae Citation Extract: Geller BL, Li L, Martinez F, Sully E, Sturge CR, Daly SM, Pybus C, Greenberg DE. Morpholino oligomers tested in vitro, in biofilm and in vivo against multidrug-resistant Klebsiella pneumoniae. J Antimicrob Chemother. 2018;[Epub ahead of print] doi:10.1093/jac/dky058. |
[An improved method for in vivo electroporation of morpholinos into the adult zebrafish retina]
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Citation:
Sheng Li Xue Bao. 2018 Feb 25;70(1):47-51. Chinese Epub:
Not Epub Abstract:
In vivo electroporation of morpholinos (MOs) into the retina of adult zebrafish is an efficient method to study gene function... Delivery Method:
electroporation Organism or Cell Type:
zebrafish Citation Extract: Hou HT, Lv JY, Zhang ZQ, Lu Y, Zhou CP, Zhou TQ, Zhang SQ, Xu H. [An improved method for in vivo electroporation of morpholinos into the adult zebrafish retina]. Sheng Li Xue Bao. 2018 Feb 25;70(1):47-51. Chinese. |