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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia

Authors:
Danilova N, Wilkes M, Bibikova E, Youn M-Y, Sakamoto KM, Lin S
Citation:
Sci Rep. 2018;8:5165. doi:10.1038/s41598-018-23561-6
Epub:
Not Epub
Abstract:
Deficiency of ribosomal proteins (RPs) leads to Diamond Blackfan Anemia (DBA) associated with anemia, congenital defects, and...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Danilova N, Wilkes M, Bibikova E, Youn M-Y, Sakamoto KM, Lin S. Innate immune system activation in zebrafish and cellular models of Diamond Blackfan Anemia. Sci Rep. 2018;8:5165. doi:10.1038/s41598-018-23561-6.

Counterregulation of cAMP-directed kinase activities controls ciliogenesis

Authors:
Porpora M, Sauchella S, Rinaldi L, Donne RD, Sepe M, Torres-Quesada O, Intartaglia D, Garbi C, Insabato L, Santoriello M, Bachmann VA, Synofzik M, Lindner HH, Conte I, Stefan E, Feliciello A
Citation:
Nat Comm. 2018;9:1224. doi:10.1038/s41467-018-03643-9
Epub:
Not Epub
Abstract:
The primary cilium emanates from the cell surface of growth-arrested cells and plays a central role in vertebrate development...
Delivery Method:
microinjection
Organism or Cell Type:
Oryzias latipes (medaka)
Citation Extract:
Porpora M, Sauchella S, Rinaldi L, Donne RD, Sepe M, Torres-Quesada O, Intartaglia D, Garbi C, Insabato L, Santoriello M, Bachmann VA, Synofzik M, Lindner HH, Conte I, Stefan E, Feliciello A. Counterregulation of cAMP-directed kinase activities controls ciliogenesis. Nat Comm. 2018;9:1224. doi:10.1038/s41467-018-03643-9.

Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons

Authors:
Bergboer JGM, Wyatt C, Austin-Tse C, Yaksi E, Drummond IA
Citation:
Cilia. 2018 Mar 15;7:2. doi: 10.1186/s13630-018-0056-1. eCollection 2018
Epub:
Not Epub
Abstract:
Background: Primary cilia mediate signal transduction by acting as an organizing scaffold for receptors, signalling proteins...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bergboer JGM, Wyatt C, Austin-Tse C, Yaksi E, Drummond IA. Assaying sensory ciliopathies using calcium biosensor expression in zebrafish ciliated olfactory neurons. Cilia. 2018 Mar 15;7:2. doi: 10.1186/s13630-018-0056-1. eCollection 2018.

Blood Flow Regulates Zebrafish Caudal Vein Plexus Angiogenesis by ERK5-klf2a-nos2b Signaling

Authors:
Xie X, Zhou T, Wang Y, Chen H, Lei D, Huang L, Wang Y, Jin X, Sun T, Tan J, Yin T, Huang J, Gregersen H, Wang G
Citation:
Curr Mol Med. 2018 Mar 22. doi: 10.2174/1566524018666180322153432. [Epub ahead of print]
Epub:
Yes
Abstract:
Vascular network formation induced by angiogenesis plays an important role in many physiological and pathological processes....
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Xie X, Zhou T, Wang Y, Chen H, Lei D, Huang L, Wang Y, Jin X, Sun T, Tan J, Yin T, Huang J, Gregersen H, Wang G. Blood Flow Regulates Zebrafish Caudal Vein Plexus Angiogenesis by ERK5-klf2a-nos2b Signaling. Curr Mol Med. 2018 Mar 22. doi: 10.2174/1566524018666180322153432. [Epub ahead of print].

MicroRNA-194 Regulates the Development and Differentiation of Sensory Patches and Statoacoustic Ganglion of Inner Ear by Fgf4

Authors:
Cao H, Shi J, Du J, Chen K, Dong C, Jiang D, Jiang H
Citation:
Med Sci Monit. 2018 Mar 23;24:1712-1723
Epub:
Not Epub
Abstract:
BACKGROUND: MicroRNA 194 is involved in the differentiation of various types of cells, such as adipose derived stem cells,...
Organism or Cell Type:
zebrafish
Citation Extract:
Cao H, Shi J, Du J, Chen K, Dong C, Jiang D, Jiang H. MicroRNA-194 Regulates the Development and Differentiation of Sensory Patches and Statoacoustic Ganglion of Inner Ear by Fgf4. Med Sci Monit. 2018 Mar 23;24:1712-1723.

The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development

Authors:
Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke AS
Citation:
PLoS Genet. 2018;14(3):e1007278. doi:10.1371/journal.pgen.1007278
Epub:
Not Epub
Abstract:
Opacification of the ocular lens, termed cataract, is a common cause of blindness. To become transparent, lens fiber cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish, Xenopus laevis
Citation Extract:
Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke AS. The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS Genet. 2018;14(3):e1007278. doi:10.1371/journal.pgen.1007278.

Molybdenum Disulfide Field-Effect Transistor Biosensor for Ultrasensitive Detection of DNA by Employing Morpholino as Probe

Authors:
Mei J, Li Y-T, Zhang H, Xiao M-M, Ning Y, Zhang Z-Y, Zhang G-J
Citation:
Biosens Bioelectr. 2018;{Epub ahead of print] doi:10.1016/j.bios.2018.03.043
Epub:
Yes
Abstract:
This work reports on a molybdenum disulfide (MoS2) based field-effect transistor (FET) biosensor for ultrasensitive label-free...
Citation Extract:
Mei J, Li Y-T, Zhang H, Xiao M-M, Ning Y, Zhang Z-Y, Zhang G-J. Molybdenum Disulfide Field-Effect Transistor Biosensor for Ultrasensitive Detection of DNA by Employing Morpholino as Probe. Biosens Bioelectr. 2018;{Epub ahead of print] doi:10.1016/j.bios.2018.03.043.

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects

Authors:
Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP
Citation:
Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901
Epub:
Yes
Abstract:
BACKGROUND: Inhibition of PKC-α (protein kinase C-α) enhances contractility and cardioprotection in animal models, but effects...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP. Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects. Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901.

Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos

Authors:
Cutler CP, Tanner P
Citation:
The Bulletin: Mount Desert Island Biological Laboratory. 2014;53:12-13
Epub:
Not Epub
Abstract:
Vivo-morpholinos are artificial nucleic acids that can block the protein production from a particular gene. Direct intestinal...
Delivery Method:
Vivo-morpholino
Organism or Cell Type:
Anguilla rostrata (American eel)
Citation Extract:
Cutler CP, Tanner P. Successful Knockdown of Aquaporin 1 (AQP1) Protein Expression in American Eel (Anguilla rostrata) Gastrointestinal Tract Using Direct-Infusions of Vivo-Morpholinos. The Bulletin: Mount Desert Island Biological Laboratory. 2014;53:12-13.

March2 is required for head formation by mediating Dishevelled degradation in concert with Dapper1

Authors:
Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK
Citation:
Development. 2018 Mar 16. pii: dev.143107. doi: 10.1242/dev.143107. [Epub ahead of print]
Epub:
Yes
Abstract:
Dishevelled (Dvl/Dsh) is a key scaffold protein that propagates Wnt signaling essential for embryogenesis and homeostasis....
Organism or Cell Type:
Xenopus
Citation Extract:
Lee H, Cheong SM, Han W, Koo Y, Jo SB, Cho GS, Yang JS, Kim S, Han JK. March2 is required for head formation by mediating Dishevelled degradation in concert with Dapper1. Development. 2018 Mar 16. pii: dev.143107. doi: 10.1242/dev.143107. [Epub ahead of print].

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