You are here

Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12353 scientific papers returned from the database with the search filters currently being used below.

Morphogenetic defects underlie Superior Coloboma, a newly identified closure disorder of the dorsal eye

Authors:
Hocking JC, Famulski JK, Yoon KH, Widen SA, Bernstein CS, Koch S, Weiss O, FORGE Canada Consortium, Agarwala S, Inbal A, Lehmann OJ, Waskiewicz AJ
Citation:
PLoS Genet. 2018;14(3):e1007246. doi:10.1371/journal.pgen.1007246
Epub:
Not Epub
Abstract:
The eye primordium arises as a lateral outgrowth of the forebrain, with a transient fissure on the inferior side of the optic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Hocking JC, Famulski JK, Yoon KH, Widen SA, Bernstein CS, Koch S, Weiss O, FORGE Canada Consortium, Agarwala S, Inbal A, Lehmann OJ, Waskiewicz AJ. Morphogenetic defects underlie Superior Coloboma, a newly identified closure disorder of the dorsal eye. PLoS Genet. 2018;14(3):e1007246. doi:10.1371/journal.pgen.1007246.

GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1

Authors:
Guo S, Zhang Y, Zhou T, Wang D, Weng Y, Chen Q, Ma J, Li Y-P, Wang L
Citation:
Cell Death Differ. 2018;[Epub] doi:10.1038/s41418-018-0083-x
Epub:
Yes
Abstract:
The role of GATA-binding protein 4 (GATA4) in neural crest cells (NCCs) is poorly defined. Here we showed that mouse NCCs...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Guo S, Zhang Y, Zhou T, Wang D, Weng Y, Chen Q, Ma J, Li Y-P, Wang L. GATA4 as a novel regulator involved in the development of the neural crest and craniofacial skeleton via Barx1. Cell Death Differ. 2018;[Epub] doi:10.1038/s41418-018-0083-x.

Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function

Authors:
Cioni J-M, Wong HH-W, Bressan D, Kodama L, Harris WA, Holt CE
Citation:
Neuron. 2018;97(5)1078-93.e6. doi:10.1016/j.neuron.2018.01.027
Epub:
Not Epub
Abstract:
The axons of retinal ganglion cells (RGCs) are topographically sorted before they arrive at the optic tectum. This pre-target...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Cioni J-M, Wong HH-W, Bressan D, Kodama L, Harris WA, Holt CE. Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function. Neuron. 2018;97(5)1078-93.e6. doi:10.1016/j.neuron.2018.01.027.

Loss of cardiac Wnt/β-catenin signalling in Desmoplakin-deficient AC8 zebrafish models is rescuable by genetic and pharmacological intervention

Authors:
Giuliodori A, Beffagna G, Marchetto G, Fornetto C, Vanzi F, Toppo S, Facchinello N, Santimaria M, Vettori A, Rizzo S, Barbera MD, Pilichou K, Argenton F, Thiene G, Tiso N, Basso C
Citation:
Cardiovasc Res. 2018;[Epub] doi.org/10.1093/cvr/cvy057
Epub:
Yes
Abstract:
Aims: Arrhythmogenic cardiomyopathy (AC) is an inherited heart disease characterized by life-threatening ventricular...
Organism or Cell Type:
zebrafish
Citation Extract:
Giuliodori A, Beffagna G, Marchetto G, Fornetto C, Vanzi F, Toppo S, Facchinello N, Santimaria M, Vettori A, Rizzo S, Barbera MD, Pilichou K, Argenton F, Thiene G, Tiso N, Basso C. Loss of cardiac Wnt/β-catenin signalling in Desmoplakin-deficient AC8 zebrafish models is rescuable by genetic and pharmacological intervention. Cardiovasc Res. 2018;[Epub] doi.org/10.1093/cvr/cvy057.

Identification of a rare BMP pathway mutation in a non-syndromic human brain arteriovenous malformation via exome sequencing

Authors:
Walcott BP, Winkler EA, Zhou S, Birk H, Guo D, Koch MJ, Stapleton CJ, Spiegelman D, Dionne-Laporte A, Dion PA, Kahle KT, Rouleau GA, Lawton MT
Citation:
Hum Genome Var. 2018;5:18001. doi:10.1038/hgv.2018.1
Epub:
Not Epub
Abstract:
Brain arteriovenous malformations (AVMs) are abnormal connections between arteries and veins that can result in hemorrhagic...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Walcott BP, Winkler EA, Zhou S, Birk H, Guo D, Koch MJ, Stapleton CJ, Spiegelman D, Dionne-Laporte A, Dion PA, Kahle KT, Rouleau GA, Lawton MT. Identification of a rare BMP pathway mutation in a non-syndromic human brain arteriovenous malformation via exome sequencing. Hum Genome Var. 2018;5:18001. doi:10.1038/hgv.2018.1.

The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation

Authors:
Dancevic CM, Gibert Y, Berger J, Smith AD, Liongue C, Stupka N, Ward AC, McCulloch DR
Citation:
Int J Mol Sci. 2018;19(3):766. doi:10.3390/ijms19030766
Epub:
Yes
Abstract:
The ADAMTS5 metzincin, a secreted zinc-dependent metalloproteinase, modulates the extracellular matrix (ECM) during limb...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dancevic CM, Gibert Y, Berger J, Smith AD, Liongue C, Stupka N, Ward AC, McCulloch DR. The ADAMTS5 Metzincin Regulates Zebrafish Somite Differentiation. Int J Mol Sci. 2018;19(3):766. doi:10.3390/ijms19030766.

CLAMP/Spef1 regulates planar cell polarity signaling and asymmetric microtubule accumulation in the Xenopus ciliated epithelia

Authors:
Kim SK, Zhang S, Werner ME, Brotslaw EJ, Mitchell JW, Altabbaa MM, Mitchell BJ
Citation:
J Cell Biol. 2018;[Epub] doi:10.1083/jcb.201706058
Epub:
Yes
Abstract:
Most epithelial cells polarize along the axis of the tissue, a feature known as planar cell polarity (PCP). The initiation of...
Organism or Cell Type:
Xenopus
Citation Extract:
Kim SK, Zhang S, Werner ME, Brotslaw EJ, Mitchell JW, Altabbaa MM, Mitchell BJ. CLAMP/Spef1 regulates planar cell polarity signaling and asymmetric microtubule accumulation in the Xenopus ciliated epithelia. J Cell Biol. 2018;[Epub] doi:10.1083/jcb.201706058.

CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-b/BMP Signaling at the Primary Cilium

Authors:
Mönnich M, Borgeskov L, Breslin L, Jakobsen L, Rogowski M, Doganli C, Schrøder JM, Mogensen JB, Blinkenkjær L, Harder LM, Lundberg E, Geimer S, Christensen ST, Andersen JS, Larsen LA, Pedersen LB
Citation:
Cell Rep. 2018;22(10):2584-92. doi:10.1016/j.celrep.2018.02.043
Epub:
Not Epub
Abstract:
The centrosome is the main microtubule-organizing center in animal cells and comprises a mother and daughter centriole...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mönnich M, Borgeskov L, Breslin L, Jakobsen L, Rogowski M, Doganli C, Schrøder JM, Mogensen JB, Blinkenkjær L, Harder LM, Lundberg E, Geimer S, Christensen ST, Andersen JS, Larsen LA, Pedersen LB. CEP128 Localizes to the Subdistal Appendages of the Mother Centriole and Regulates TGF-b/BMP Signaling at the Primary Cilium. Cell Rep. 2018;22(10):2584-92. doi:10.1016/j.celrep.2018.02.043.

zHSF1 modulates zper2 expression in zebrafish embryos

Authors:
Mennetrier L, Lopez T, Pruvot B, Yousfi N, Armant O, Hazhaz H, Lhuissiez V, Garrido C, Chluba J
Citation:
Chronobiol Int. 2018 Mar 6:1-8. doi: 10.1080/07420528.2018.1441855. [Epub ahead of print]
Epub:
Yes
Abstract:
HSF1 is a transcription factor that plays a key role in circadian resetting by temperature. We have used zebrafish embryos to...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Mennetrier L, Lopez T, Pruvot B, Yousfi N, Armant O, Hazhaz H, Lhuissiez V, Garrido C, Chluba J. zHSF1 modulates zper2 expression in zebrafish embryos. Chronobiol Int. 2018 Mar 6:1-8. doi: 10.1080/07420528.2018.1441855. [Epub ahead of print].

Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos

Authors:
Tsai TC, Shih CC, Chien HP, Yang AH, Lu JK, Lu JH
Citation:
BMC Dev Biol. 2018 Mar 5;18(1):5. doi: 10.1186/s12861-017-0161-1
Epub:
Not Epub
Abstract:
BACKGROUND: Tbx5 deficiency in zebrafish causes several abnormal phenotypes of the heart and pectoral fins. It has been...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Tsai TC, Shih CC, Chien HP, Yang AH, Lu JK, Lu JH. Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos. BMC Dev Biol. 2018 Mar 5;18(1):5. doi: 10.1186/s12861-017-0161-1.

Pages