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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
There are 12138 scientific papers returned from the database with the search filters currently being used below.
Effects of light illumination and the expression of wee1 on tissue regeneration in adult zebrafish
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Citation:
Biochem Biophys Res Commun. 2012 Oct 10. pii: S0006-291X(12)01958-4. doi: 10.1016/j.bbrc.2012.10.021. [Epub ahead of print] Epub:
Not Epub Abstract:
The zebrafish exhibits an enhanced capability of regenerating most of its adult tissues. In this study, we examine the roles of... Delivery Method:
Injection Organism or Cell Type:
zebrafish Citation Extract: Ye Q, Chen D, Xi Y, Li J, Shao J, Li L. Effects of light illumination and the expression of wee1 on tissue regeneration in adult zebrafish. Biochem Biophys Res Commun. 2012 Oct 10. pii: S0006-291X(12)01958-4. doi: 10.1016/j.bbrc.2012.10.021. [Epub ahead of print]. |
Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs
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Citation:
Ann Neurol. 2009 Jun;65(6):667-76. doi: 10.1002/ana.21627. Epub:
Not Epub Abstract:
OBJECTIVE: Duchenne muscular dystrophy (DMD) is caused by the inability to produce dystrophin protein at the myofiber membrane... Delivery Method:
in vivo: injection Organism or Cell Type:
Dog, beagle CXMD (DMD model) Citation Extract: Yokota T, Lu QL, Partridge T, Kobayashi M, Nakamura A, Takeda S, Hoffman E. Efficacy of systemic morpholino exon-skipping in duchenne dystrophy dogs. Ann Neurol. 2009 Jun;65(6):667-76. doi: 10.1002/ana.21627.. |
Essential requirement for zebrafish anosmin-1a in the migration of the posterior lateral line primordium
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Citation:
Dev Biol. 2008 Jun 13. [Epub ahead of print] Epub:
Not Epub Abstract:
Kallmann syndrome (KS) is a human genetic disease that impairs both cell migration and axon elongation. The KAL-1 gene... Organism or Cell Type:
zebrafish Citation Extract: Yanicostas C, Ernest S, Dayraud C, Petit C, Soussi-Yanicostas N. Essential requirement for zebrafish anosmin-1a in the migration of the posterior lateral line primordium. Dev Biol. 2008 Jun 13. [Epub ahead of print]. |
Exocrine pancreas development in zebrafish
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Citation:
Dev Biol. 2005 Aug 1;284(1):84-101. Epub:
Not Epub Abstract:
Although many of the genes that regulate development of the endocrine pancreas have been identified, comparatively little is... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Yee NS, Lorent K, Pack M. Exocrine pancreas development in zebrafish. Dev Biol. 2005 Aug 1;284(1):84-101.. |
Exogenous control of mammalian gene expression through modulation of RNA self-cleavage
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Citation:
Nature. 2004 Sep 23;431(7007):471-6 Epub:
Not Epub Abstract:
Recent studies on the control of specific metabolic pathways in bacteria have documented the existence of entirely RNA-based... Delivery Method:
in vitro: TNT Organism or Cell Type:
not applicable Citation Extract: Yen L, Svendsen J, Lee JS, Gray JT, Magnier M, Baba T, D'Amato RJ, Mulligan RC. Exogenous control of mammalian gene expression through modulation of RNA self-cleavage. Nature. 2004 Sep 23;431(7007):471-6. |
Extensive and Prolonged Restoration of Dystrophin Expression with Vivo-Morpholino-Mediated Multiple Exon Skipping in Dystrophic Dogs
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Citation:
Nucleic Acid Ther. 2012 Oct;22(5):306-15. doi: 10.1089/nat.2012.0368. Epub 2012 Aug 13. Epub:
Not Epub Abstract:
Duchenne muscular dystrophy (DMD) is a severe and the most prevalent form of muscular dystrophy, characterized by rapid... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
Dog, beagle CXMD (DMD model) Citation Extract: Yokota T, Nakamura A, Nagata T, Saito T, Kobayashi M, Aoki Y, Echigoya Y, Partridge T, Hoffman EP, Takeda S. Extensive and Prolonged Restoration of Dystrophin Expression with Vivo-Morpholino-Mediated Multiple Exon Skipping in Dystrophic Dogs. Nucleic Acid Ther. 2012 Oct;22(5):306-15. doi: 10.1089/nat.2012.0368. Epub 2012 Aug 13.. |
Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish
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Citation:
Genes Dev. 2008 Mar 15;22(6):728-33 Epub:
Not Epub Abstract:
Appendage regeneration is defined by rapid changes in gene expression that achieve dramatic developmental effects, suggesting... Delivery Method:
Microinjection then electroporation Organism or Cell Type:
zebrafish Citation Extract: Yin VP, Thomson JM, Thummel R, Hyde DR, Hammond SM, Poss KD. Fgf-dependent depletion of microRNA-133 promotes appendage regeneration in zebrafish. Genes Dev. 2008 Mar 15;22(6):728-33. |
Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO
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Citation:
Mol Ther. 2010 Aug 10. [Epub ahead of print] Epub:
Not Epub Abstract:
Splice modulation using antisense oligonucleotides (AOs) has been shown to yield targeted exon exclusion to restore the open... Delivery Method:
i.v. injection Organism or Cell Type:
mice, mdx Citation Extract: Yin H, Moulton HM, Betts C, Merritt T, Seow Y, Ashraf S, Wang Q, Boutilier J, Wood MJ. Functional Rescue of Dystrophin-deficient mdx Mice by a Chimeric Peptide-PMO. Mol Ther. 2010 Aug 10. [Epub ahead of print]. |
Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult
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Citation:
Biochem Pharmacol. 2007 Mar 15;73(6):782-92. Epub 2006 Dec 3 Epub:
Not Epub Abstract:
Hepatocellular carcinoma is a very common malignancy and is chemoresistant to currently available chemotherapeutic agents.... Delivery Method:
Endo-Porter Organism or Cell Type:
cell culture: human hepatocyte Hep3B Citation Extract: Yeh TC, Chiang PC, Li TK, Hsu JL, Lin CJ, Wang SW, Peng CY, Guh JH. Genistein induces apoptosis in human hepatocellular carcinomas via interaction of endoplasmic reticulum stress and mitochondrial insult. Biochem Pharmacol. 2007 Mar 15;73(6):782-92. Epub 2006 Dec 3. |
Gα(13) is closely related to hematopoiesis in zebrafish
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Citation:
Mol Biol Rep. 2010 Nov 27. [Epub ahead of print] Epub:
Not Epub Abstract:
Heterotrimeric guanine nucleotide-binding regulatory proteins (G proteins) function as signal transducers and control many... Organism or Cell Type:
zebrafish Citation Extract: Ye D, Yang Q, Li Y, Huang X, Hu J, Qian S, Tan Z, Song P. Gα(13) is closely related to hematopoiesis in zebrafish. Mol Biol Rep. 2010 Nov 27. [Epub ahead of print]. |