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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Zebrafish Models for Dyskeratosis Congenita Reveal Critical Roles of p53 Activation Contributing to Hematopoietic Defects through RNA Processing

Authors:
Zhang Y, Morimoto K, Danilova N, Zhang B, Lin S
Citation:
PLoS ONE. 2012;7(1):e30188. doi:10.1371/journal.pone.0030188
Epub:
Not Epub
Abstract:
Dyskeratosis congenita (DC) is a rare bone marrow failure syndrome in which hematopoietic defects are the main cause of...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang Y, Morimoto K, Danilova N, Zhang B, Lin S. Zebrafish Models for Dyskeratosis Congenita Reveal Critical Roles of p53 Activation Contributing to Hematopoietic Defects through RNA Processing. PLoS ONE. 2012;7(1):e30188. doi:10.1371/journal.pone.0030188.

ZMYND10 Is Mutated in Primary Ciliary Dyskinesia and Interacts with LRRC6

Authors:
Zariwala MA, Gee HY, Kurkowiak M, Al-Mutairi DA, Leigh MW, Hurd TW, Hjeij R, Dell SD, Chaki M, Dougherty GW, Adan M, Spear PC, Esteve-Rudd J, Loges NT, Rosenfeld M, Diaz KA, Olbrich H, Wolf WE, Sheridan E, Batten TF, Halbritter J, Porath JD, Kohl S, Lovric S, Hwang DY, Pittman JE, Burns KA, Ferkol TW, Sagel SD, Olivier KN, Morgan LC, Werner C, Raidt J, Pennekamp P, Sun Z, Zhou W, Airik R, Natarajan S, Allen SJ, Amirav I, Wieczorek D, Landwehr K, Nielsen K, Schwerk N, Sertic J, Köhler G, Washburn J, Levy S, Fan S, Koerner-Rettberg C, Amselem S, Williams DS, Mitchell BJ, Drummond IA, Otto EA, Omran H, Knowles MR, Hildebrandt F.
Citation:
Am J Hum Genet. 2013 Jul 24. doi:pii: S0002-9297(13)00276-0. 10.1016/j.ajhg.2013.06.007. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Defects of motile cilia cause primary ciliary dyskinesia (PCD), characterized by recurrent respiratory infections and male...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zariwala MA, Gee HY, Kurkowiak M, Al-Mutairi DA, Leigh MW, Hurd TW, Hjeij R, Dell SD, Chaki M, Dougherty GW, Adan M, Spear PC, Esteve-Rudd J, Loges NT, Rosenfeld M, Diaz KA, Olbrich H, Wolf WE, Sheridan E, Batten TF, Halbritter J, Porath JD, Kohl S, Lovric S, Hwang DY, Pittman JE, Burns KA, Ferkol TW, Sagel SD, Olivier KN, Morgan LC, Werner C, Raidt J, Pennekamp P, Sun Z, Zhou W, Airik R, Natarajan S, Allen SJ, Amirav I, Wieczorek D, Landwehr K, Nielsen K, Schwerk N, Sertic J, Köhler G, Washburn J, Levy S, Fan S, Koerner-Rettberg C, Amselem S, Williams DS, Mitchell BJ, Drummond IA, Otto EA, Omran H, Knowles MR, Hildebrandt F. . ZMYND10 Is Mutated in Primary Ciliary Dyskinesia and Interacts with LRRC6. Am J Hum Genet. 2013 Jul 24. doi:pii: S0002-9297(13)00276-0. 10.1016/j.ajhg.2013.06.007. [Epub ahead of print].

[Knockdown and overexpression of miR-219 lead to embryonic defects in zebrafish development]

Authors:
Zhang MC, Lv Y, Qi YT, Zhang Z, Fu XN, Yuan CG, Lai LH
Citation:
Fen Zi Xi Bao Sheng Wu Xue Bao. 2008 Oct;41(5):341-8. Chinese.
Epub:
Not Epub
Abstract:
MicroRNAs (miRNAs) are important post-transcriptional modulators of gene expression, which have been implicated in many...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang MC, Lv Y, Qi YT, Zhang Z, Fu XN, Yuan CG, Lai LH. [Knockdown and overexpression of miR-219 lead to embryonic defects in zebrafish development]. Fen Zi Xi Bao Sheng Wu Xue Bao. 2008 Oct;41(5):341-8. Chinese. .

β-Catenin 1 and β-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos

Authors:
Zhang M, Zhang J, Lin SC, Meng A
Citation:
Development. 2012 Apr 25. [Epub ahead of print]
Epub:
Not Epub
Abstract:
β-Catenin-mediated canonical Wnt signaling has been found to be required for left-right (LR) asymmetric development. However,...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhang M, Zhang J, Lin SC, Meng A. β-Catenin 1 and β-catenin 2 play similar and distinct roles in left-right asymmetric development of zebrafish embryos. Development. 2012 Apr 25. [Epub ahead of print].

14-3-3 proteins regulate retinal axon growth by modulating ADF/cofilin activity

Authors:
Yoon BC, Zivraj KH, Strochlic L, Holt CE
Citation:
Dev Neurobiol. 2012 Apr;72(4):600-14. doi: 10.1002/dneu.20955.
Epub:
Not Epub
Abstract:
Precise navigation of axons to their targets is critical for establishing proper neuronal networks during development. Axon...
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yoon BC, Zivraj KH, Strochlic L, Holt CE. 14-3-3 proteins regulate retinal axon growth by modulating ADF/cofilin activity. Dev Neurobiol. 2012 Apr;72(4):600-14. doi: 10.1002/dneu.20955..

A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice

Authors:
Yin H, Moulton HM, Betts C, Seow Y, Boutilier J, Iverson PL, Wood MJ
Citation:
Hum Mol Genet. 2009 Aug 18. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Duchenne muscular dystrophy (DMD) is caused by mutations in the DMD gene that abolish the synthesis of dystrophin protein....
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice, mdx
Citation Extract:
Yin H, Moulton HM, Betts C, Seow Y, Boutilier J, Iverson PL, Wood MJ. A fusion peptide directs enhanced systemic dystrophin exon skipping and functional restoration in dystrophin-deficient mdx mice. Hum Mol Genet. 2009 Aug 18. [Epub ahead of print].

A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor

Authors:
Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J
Citation:
Development. 2003 May;130(10):2199-212. Erratum in: Development. 2004 Aug;13(15):3821
Epub:
Not Epub
Abstract:
Convergent extension behaviour is critical for the formation of the vertebrate body axis. In Xenopus, components of the Wnt...
Delivery Method:
Microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Yokota C, Kofron M, Zuck M, Houston DW, Isaacs H, Asashima M, Wylie CC, Heasman J. A novel role for a nodal-related protein; Xnr3 regulates convergent extension movements via the FGF receptor. Development. 2003 May;130(10):2199-212. Erratum in: Development. 2004 Aug;13(15):3821.

A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground

Authors:
Yokota T, Takeda S, Lu QL, Partridge TA, Nakamura A, Hoffman EP
Citation:
Arch Neurol. 2009 Jan;66(1):32-8
Epub:
Not Epub
Abstract:
Antisense oligonucleotides are short nucleic acid sequences designed for use as small-molecule drugs. They recognize and bind...
Citation Extract:
Yokota T, Takeda S, Lu QL, Partridge TA, Nakamura A, Hoffman EP. A renaissance for antisense oligonucleotide drugs in neurology: exon skipping breaks new ground. Arch Neurol. 2009 Jan;66(1):32-8.

A Zebrafish Forebrain-Specific Zinc Finger Gene Can Induce Ectopic dlx2 and dlx6 Expression

Authors:
Yang Z, Liu N, Lin S
Citation:
Dev Biol 2001 Mar 1;231(1):138-148
Epub:
Not Epub
Abstract:
Identification of the earliest forebrain-specific markers should facilitate the elucidation of molecular events underlying...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yang Z, Liu N, Lin S. A Zebrafish Forebrain-Specific Zinc Finger Gene Can Induce Ectopic dlx2 and dlx6 Expression. Dev Biol 2001 Mar 1;231(1):138-148.

AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression

Authors:
Yeh JR, Munson KM, Chao YL, Peterson QP, Macrae CA, Peterson RT
Citation:
Development. 2008 Jan;135(2):401-10
Epub:
Not Epub
Abstract:
AML1-ETO is one of the most common chromosomal translocation products associated with acute myelogenous leukemia (AML)....
Organism or Cell Type:
zebrafish
Citation Extract:
Yeh JR, Munson KM, Chao YL, Peterson QP, Macrae CA, Peterson RT. AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression. Development. 2008 Jan;135(2):401-10.

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