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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12343 scientific papers returned from the database with the search filters currently being used below.
There are 12343 scientific papers returned from the database with the search filters currently being used below.
Therapeutic Potential of Splice-Switching Oligonucleotides
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Citation:
Oligonucleotides. 2009 Jan 6. [Epub ahead of print] Epub:
Not Epub Abstract:
Alternative splicing enables a single pre-messenger RNA transcript to yield multiple protein isoforms, making it a major... Citation Extract: Bauman J, Jearawiriyapaisarn N, Kole R. Therapeutic Potential of Splice-Switching Oligonucleotides. Oligonucleotides. 2009 Jan 6. [Epub ahead of print]. |
TIF1gamma controls erythroid cell fate by regulating transcription elongation
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Citation:
Cell. 2010 Jul 9;142(1):133-43 Epub:
Not Epub Abstract:
Recent genome-wide studies have demonstrated that pausing of RNA polymerase II (Pol II) occurred on many vertebrate genes. By... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bai X, Kim J, Yang Z, Jurynec MJ, Akie TE, Lee J, LeBlanc J, Sessa A, Jiang H, DiBiase A, Zhou Y, Grunwald DJ, Lin S, Cantor AB, Orkin SH, Zon LI. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Cell. 2010 Jul 9;142(1):133-43. |
Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats
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Citation:
Pharm Res. 2002 Oct;19(10):1465-70 Epub:
Not Epub Abstract:
PURPOSE: To determine if dermal absorption of an antisense phosphorodiamidate Morpholino oligomers (PMO) can inhibit target... Delivery Method:
transdermal Organism or Cell Type:
Sprague Dawley rats & hairless CRL:SK1 mice Citation Extract: Arora V, Hannah TL, Iversen PL, Brand RM. Transdermal use of phosphorodiamidate morpholino oligomer AVI-4472 inhibits cytochrome P450 3A2 activity in male rats. Pharm Res. 2002 Oct;19(10):1465-70. |
Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif
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Citation:
Nucleic Acids Res 2001 Dec 1;29(23):4873-80 Epub:
Not Epub Abstract:
Triplex-forming oligonucleotides (TFOs) are good candidates to be used as site-specific DNA-binding agents. Two obstacles... Delivery Method:
not applicable Organism or Cell Type:
not applicable Citation Extract: Basye J, Trent JO, Gao D, Ebbinghaus SW. Triplex formation by morpholino oligodeoxyribonucleotides in the HER-2/neu promoter requires the pyrimidine motif. Nucleic Acids Res 2001 Dec 1;29(23):4873-80. |
Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling
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Citation:
Development. 2008 Sep;135(17):2927-37 Epub:
Not Epub Abstract:
We identify Balpha (PPP2R2A) and Bdelta (PPP2R2D), two highly related members of the B family of regulatory subunits of the... Organism or Cell Type:
Xenopus Citation Extract: Batut J, Schmierer B, Cao J, Raftery LA, Hill CS, Howell M. Two highly related regulatory subunits of PP2A exert opposite effects on TGF-beta/Activin/Nodal signalling. Development. 2008 Sep;135(17):2927-37. |
U1 snRNP determines mRNA length and regulates isoform expression
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Citation:
Cell. 2012 Jul 6;150(1):53-64. doi: 10.1016/j.cell.2012.05.029 Epub:
Not Epub Abstract:
U1 snRNP (U1), in addition to its splicing role, protects pre-mRNAs from drastic premature termination by cleavage and... Delivery Method:
Electroporation Organism or Cell Type:
cell culture: HeLa, NIH/3T3, and S2 cells Citation Extract: Berg MG, Singh LN, Younis I, Liu Q, Pinto AM, Kaida D, Zhang Z, Cho S, Sherrill-Mix S, Wan L, Dreyfuss G. U1 snRNP determines mRNA length and regulates isoform expression. Cell. 2012 Jul 6;150(1):53-64. doi: 10.1016/j.cell.2012.05.029. |
Williams Syndrome Transcription Factor is critical for neural crest cell function in Xenopus laevis
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Citation:
Mech Dev. 2012 Jun 9. [Epub ahead of print] Epub:
Not Epub Abstract:
Williams Syndrome Transcription Factor (WSTF) is one of ∼25 haplodeficient genes in patients with the complex developmental... Delivery Method:
Microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Barnett C, Yazgan O, Kuo HC, Malakar S, Thomas T, Fitzgerald A, Harbour B, Henry JJ, Krebs JE. Williams Syndrome Transcription Factor is critical for neural crest cell function in Xenopus laevis. Mech Dev. 2012 Jun 9. [Epub ahead of print]. |
WNK1/HSN2 Mutation in Human Peripheral Neuropathy Deregulates KCC2 Expression and Posterior Lateral Line Development in Zebrafish (Danio rerio)
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Citation:
PLoS Genet. 2013;9(1):e1003124. doi:10.1371/journal.pgen.1003124 Epub:
Not Epub Abstract:
Hereditary sensory and autonomic neuropathy type 2 (HSNAII) is a rare pathology characterized by an early onset of severe... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Bercier V, Brustein E, Liao M, Dion PA, Lafrenière RG, Rouleau GA, Drapeau P. WNK1/HSN2 Mutation in Human Peripheral Neuropathy Deregulates KCC2 Expression and Posterior Lateral Line Development in Zebrafish (Danio rerio). PLoS Genet. 2013;9(1):e1003124. doi:10.1371/journal.pgen.1003124. |
Zebrafish as a model for myelopoiesis during embryogenesis
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Citation:
Exp Hematol. 2005 Sep;33(9):997-1006 Epub:
Not Epub Abstract:
Zebrafish produce nearly identical hematopoeitic cell lineages to those found in mammals and other higher vertebrates. As in... Delivery Method:
Microinjection Organism or Cell Type:
zebrafish Citation Extract: Berman JN, Kanki JP, Look AT. Zebrafish as a model for myelopoiesis during embryogenesis. Exp Hematol. 2005 Sep;33(9):997-1006. |
Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia
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Citation:
Am Journal Hum Genet. 2013;93(4):672-686 Epub:
Not Epub Abstract:
Primary ciliary dyskinesia (PCD) is caused when defects of motile cilia lead to chronic airway infections, male infertility,... Organism or Cell Type:
zebrafish Citation Extract: Austin-Tse C, Halbritter J, Zariwala MA, Gilberti RM, Gee HY, Hellman N, Pathak N, Liu Y, Panizzi JR, Patel-King RS, Tritschler D Bower R, O'Toole E, Porath JD, Hurd TW, Chaki M, Diaz KA, Kohl S, Lovric S, Hwang D-Y, Braun DA, Schueler M, Airik R, Otto EA, Leigh MW, Noone PG, Carson JL, Davis SD, Pittman JE, Ferkol TW, Atkinson JJ, Olivier KN, Sagel SD, Dell SD, Rosenfeld M, Milla CE, Loges NT, Omran H, Porter ME, King SM, Knowles MR, Drummond IA, Hildebrandt F.. Zebrafish Ciliopathy Screen Plus Human Mutational Analysis Identifies C21orf59 and CCDC65 Defects as Causing Primary Ciliary Dyskinesia. Am Journal Hum Genet. 2013;93(4):672-686. |