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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12511 scientific papers returned from the database with the search filters currently being used below.

Photoreceptor morphology is severely affected in the beta,beta-carotene-15,15'-oxygenase (bcox) zebrafish morphant

Authors:
Biehlmaier O, Lampert JM, Lintig JV, Kohler K
Citation:
Eur J Neurosci. 2005 Jan;21(1):59-68
Epub:
Not Epub
Abstract:
The retinoic acid molecule, a vitamin A derivative, is of key importance for eye and photoreceptor development in vertebrates....
Delivery Method:
Injection
Organism or Cell Type:
zebrafish
Citation Extract:
Biehlmaier O, Lampert JM, Lintig JV, Kohler K. Photoreceptor morphology is severely affected in the beta,beta-carotene-15,15'-oxygenase (bcox) zebrafish morphant. Eur J Neurosci. 2005 Jan;21(1):59-68.

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

Authors:
Betts C, Saleh A, Arzumanov A, Hammond S, Godfrey C, Coursindel T, Gait M, Wood M
Citation:
Mol Ther Nucleic Acids. 2012;[Epub ahead of print] http://dx.doi.org/10.1038/mtna.2012.30
Epub:
Not Epub
Abstract:
Antisense oligonucleotides (AOs) are currently the most promising therapeutic intervention for Duchenne muscular dystrophy (DMD...
Delivery Method:
peptide-coupled
Organism or Cell Type:
mice (mdx), cultured mdx myotubes
Citation Extract:
Betts C, Saleh A, Arzumanov A, Hammond S, Godfrey C, Coursindel T, Gait M, Wood M. Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment. Mol Ther Nucleic Acids. 2012;[Epub ahead of print] http://dx.doi.org/10.1038/mtna.2012.30.

Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis

Authors:
Bisgrove BW, Snarr BS, Emrazian A, Yost HJ
Citation:
Dev Biol. 2005 Nov 15;287(2):274-88. Epub 2005 Oct 7.
Epub:
Not Epub
Abstract:
Recently, it has become clear that motile cilia play a central role in initiating a left-sided signaling cascade important in...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Bisgrove BW, Snarr BS, Emrazian A, Yost HJ. Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. Dev Biol. 2005 Nov 15;287(2):274-88. Epub 2005 Oct 7..

Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation

Authors:
Biswas S, Emond MR, Jontes JD
Citation:
JCB. 2010;191(5):1029-41 doi: 10.1083/jcb.201007008
Epub:
Not Epub
Abstract:
The protocadherins comprise the largest subgroup within the cadherin superfamily, yet their cellular and developmental...
Organism or Cell Type:
zebrafish
Citation Extract:
Biswas S, Emond MR, Jontes JD. Protocadherin-19 and N-cadherin interact to control cell movements during anterior neurulation. JCB. 2010;191(5):1029-41 doi: 10.1083/jcb.201007008.

Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo

Authors:
Bessodes N, Haillot E, Duboc V, Röttinger E, Lahaye F, Lepage T
Citation:
PLoS Genet. 2012;8(12):e1003121. doi:10.1371/journal.pgen.1003121
Epub:
Not Epub
Abstract:
During echinoderm development, expression of nodal on the right side plays a crucial role in positioning of the rudiment on the...
Delivery Method:
Microinjection
Organism or Cell Type:
Sea urchin, Paracentrotus lividus
Citation Extract:
Bessodes N, Haillot E, Duboc V, Röttinger E, Lahaye F, Lepage T. Reciprocal Signaling between the Ectoderm and a Mesendodermal Left-Right Organizer Directs Left-Right Determination in the Sea Urchin Embryo. PLoS Genet. 2012;8(12):e1003121. doi:10.1371/journal.pgen.1003121.

Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide

Authors:
Bieberich E, MacKinnon S, Silva J, Noggle S, Condie BG
Citation:
J Cell Biol. 2003 Aug 4;162(3):469-79.
Epub:
Not Epub
Abstract:
Cell death and survival of neural progenitor (NP) cells are determined by signals that are largely unknown. We have analyzed...
Delivery Method:
Special Delivery
Organism or Cell Type:
cell culture: Neural progenitor cells from mouse embryonic stem cells
Citation Extract:
Bieberich E, MacKinnon S, Silva J, Noggle S, Condie BG. Regulation of cell death in mitotic neural progenitor cells by asymmetric distribution of prostate apoptosis response 4 (PAR-4) and simultaneous elevation of endogenous ceramide. J Cell Biol. 2003 Aug 4;162(3):469-79..

Reverse genetics technology for Rift Valley fever virus: current and future applications for the development of therapeutics and vaccines

Authors:
Bouloy M, Flick R
Citation:
Antiviral Res. 2009 Nov;84(2):101-18. Epub 2009 Aug 12. Review
Epub:
Not Epub
Abstract:
The advent of reverse genetics technology has revolutionized the study of RNA viruses, making it possible to manipulate their...
Delivery Method:
peptide-coupled
Citation Extract:
Bouloy M, Flick R. Reverse genetics technology for Rift Valley fever virus: current and future applications for the development of therapeutics and vaccines. Antiviral Res. 2009 Nov;84(2):101-18. Epub 2009 Aug 12. Review.

RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow

Authors:
Bisgrove BW, Makova S, Yost HJ, Brueckner M
Citation:
Dev Biol. 2011 Dec 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Motile cilia create asymmetric fluid flow in the evolutionarily conserved ciliated organ of asymmetry (COA) and play a...
Organism or Cell Type:
zebrafish
Citation Extract:
Bisgrove BW, Makova S, Yost HJ, Brueckner M. RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow. Dev Biol. 2011 Dec 29. [Epub ahead of print].

Selective blockade of gene expression in a single identified snail neuron.

Authors:
Boguslavsky D, Ierusalimsky V, Malyshev A, Balaban P, Belyavsky A.
Citation:
Neuroscience 2003 Jun 18;119(1):15-18
Epub:
Not Epub
Abstract:
In the present study, the applicability of antisense morpholino oligos for loss-of-function experiments in neurobiology was...
Delivery Method:
Microinjection
Organism or Cell Type:
Helix lucorum (snail)
Citation Extract:
Boguslavsky D, Ierusalimsky V, Malyshev A, Balaban P, Belyavsky A.. Selective blockade of gene expression in a single identified snail neuron.. Neuroscience 2003 Jun 18;119(1):15-18.

Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish

Authors:
Blasiole B, Canfield VA, Vollrath MA, Huss D, Mohideen MA, Dickman JD, Cheng KC, Fekete DM, Levenson R
Citation:
Dev Biol. 2006 Jun 1;294(1):148-60. Epub 2006 Mar 29
Epub:
Not Epub
Abstract:
We have investigated the role of Na,K-ATPase genes in zebrafish ear development. Six Na,K-ATPase genes are differentially...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Blasiole B, Canfield VA, Vollrath MA, Huss D, Mohideen MA, Dickman JD, Cheng KC, Fekete DM, Levenson R. Separate Na,K-ATPase genes are required for otolith formation and semicircular canal development in zebrafish. Dev Biol. 2006 Jun 1;294(1):148-60. Epub 2006 Mar 29.

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