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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12497 scientific papers returned from the database with the search filters currently being used below.

Knockdown of Pex11β reveals its pivotal role in regulating peroxisomal genes, numbers, and ROS levels in Xenopus laevis A6 cells

Authors:
Fox MA, Nieuwesteeg MA, Willson JA, Cepeda M, Damjanovski S
Citation:
In Vitro Cell Dev Biol Anim. 2013 Nov 14. [Epub ahead of print]
Epub:
Yes
Abstract:
Peroxisomes are organelles that are ubiquitously found in all eukaryotic cells. Enzymes within their lumen are responsible for...
Organism or Cell Type:
cell culture: Xenopus laevis A6 cells
Citation Extract:
Fox MA, Nieuwesteeg MA, Willson JA, Cepeda M, Damjanovski S. Knockdown of Pex11β reveals its pivotal role in regulating peroxisomal genes, numbers, and ROS levels in Xenopus laevis A6 cells. In Vitro Cell Dev Biol Anim. 2013 Nov 14. [Epub ahead of print].

Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice

Authors:
Pandey SN, Lee YC, Yokota T, Chen YW
Citation:
Mol Ther. 2013 Nov 14. doi: 10.1038/mt.2013.263. [Epub ahead of print]
Epub:
Yes
Abstract:
Paired-like homeodomain transcription factor 1 (PITX1) was proposed to be part of the disease mechanisms of facioscapulohumeral...
Link:
http://www.nature.com/mt/journal/vaop/naam/abs/mt2013263a.html
Delivery Method:
Vivo-Morpholino
Organism or Cell Type:
mouse
Citation Extract:
Pandey SN, Lee YC, Yokota T, Chen YW. Morpholino treatment improves muscle function and pathology of Pitx1 transgenic mice. Mol Ther. 2013 Nov 14. doi: 10.1038/mt.2013.263. [Epub ahead of print].

The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis

Authors:
Kapp LD, Abrams EW, Marlow FL, Mullins MC
Citation:
PLoS Genet. 2013;9(10):e1003822. doi:10.1371/journal.pgen.1003822
Epub:
Not Epub
Abstract:
Dorsoventral patterning of the embryonic axis relies upon the mutual antagonism of competing signaling pathways to establish a...
Link:
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1003822
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kapp LD, Abrams EW, Marlow FL, Mullins MC. The Integrator Complex Subunit 6 (Ints6) Confines the Dorsal Organizer in Vertebrate Embryogenesis. PLoS Genet. 2013;9(10):e1003822. doi:10.1371/journal.pgen.1003822.

Par6b Regulates the Dynamics of Apicobasal Polarity during Development of the Stratified Xenopus Epidermis

Authors:
Wang S, Cha S-W, Zorn AM, Wylie C
Citation:
PLoS ONE. 2013;8(10): e76854. doi:10.1371/journal.pone.0076854
Epub:
Not Epub
Abstract:
During early vertebrate development, epithelial cells establish and maintain apicobasal polarity, failure of which can cause...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0076854
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Wang S, Cha S-W, Zorn AM, Wylie C. Par6b Regulates the Dynamics of Apicobasal Polarity during Development of the Stratified Xenopus Epidermis. PLoS ONE. 2013;8(10): e76854. doi:10.1371/journal.pone.0076854.

Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings

Authors:
Zdebik AA, Mahmood F, Stanescu HC, Kleta R, Bockenhauer D, Russell C
Citation:
PLoS ONE. 2013;8(11):e79765. doi:10.1371/journal.pone.0079765
Epub:
Not Epub
Abstract:
We aimed to develop and validate a reliable method for stable long-term recordings of EEG activity in zebrafish, which is less...
Link:
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0079765
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zdebik AA, Mahmood F, Stanescu HC, Kleta R, Bockenhauer D, Russell C. Epilepsy in kcnj10 Morphant Zebrafish Assessed with a Novel Method for Long-Term EEG Recordings. PLoS ONE. 2013;8(11):e79765. doi:10.1371/journal.pone.0079765.

Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region

Authors:
Ellery PER, Maroney SA, Martinez ND, Wickens MP, Mast AE
Citation:
Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14.
Epub:
Yes
Abstract:
Objective: Tissue factor pathway inhibitor (TFPI) blocks the initiation of coagulation by inhibiting TF-activated factor VII,...
Link:
http://atvb.ahajournals.org/content/early/2013/11/14/ATVBAHA.113.302660.abstract
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: MDA-MB-231 cells
Citation Extract:
Ellery PER, Maroney SA, Martinez ND, Wickens MP, Mast AE. Translation of Human Tissue Factor Pathway Inhibitor-β mRNA Is Controlled by Alternative Splicing Within the 5′ Untranslated Region. Arterioscler Thromb Vasc Biol. 2014 Jan;34(1):187-95. doi: 10.1161/ATVBAHA.113.302660. Epub 2013 Nov 14..

Oligonucleotide therapeutics in cancer

Authors:
Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R
Citation:
Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9
Epub:
Not Epub
Abstract:
Alterations in pre-mRNA splicing can have profound effects on gene expression and lead to cellular transformation....
Link:
http://link.springer.com/chapter/10.1007%2F978-3-642-31659-3_9
Citation Extract:
Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Oligonucleotide therapeutics in cancer. Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9.

Podocalyxin regulates pronephric glomerular development in zebrafish

Authors:
Ichimura K, Powell R, Nakamura T, Kurihara H, Sakai T, Obara T
Citation:
Physiol Rep. 2013 Aug;1(3). doi:pii: e00074
Epub:
Not Epub
Abstract:
Vertebrate glomerular podocytes possess a highly sialylated transmembrane glycoprotein, Podocalyxin. In mammals, the sialic...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/phy2.74/full
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ichimura K, Powell R, Nakamura T, Kurihara H, Sakai T, Obara T. Podocalyxin regulates pronephric glomerular development in zebrafish. Physiol Rep. 2013 Aug;1(3). doi:pii: e00074.

Piwi regulates Vasa accumulation during embryogenesis in the sea urchin

Authors:
Yajima M, Gustafson EA, Song JL, Wessel GM
Citation:
Dev Dyn. 2013 Nov 12. doi: 10.1002/dvdy.24096. [Epub ahead of print]
Epub:
Yes
Abstract:
Background: Piwi proteins are essential for germ line development, stem cell maintenance, and more recently found to function...
Link:
http://onlinelibrary.wiley.com/doi/10.1002/dvdy.24096/abstract
Organism or Cell Type:
Sea urchin: Strongylocentrotus purpuratus
Citation Extract:
Yajima M, Gustafson EA, Song JL, Wessel GM. Piwi regulates Vasa accumulation during embryogenesis in the sea urchin. Dev Dyn. 2013 Nov 12. doi: 10.1002/dvdy.24096. [Epub ahead of print].

A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis

Authors:
Kotkamp K, Mössner R, Allen A, Onichtchouk D, Driever W
Citation:
Dev Biol. 2013 Nov 5. doi:pii: S0012-1606(13)00580-0. 10.1016/j.ydbio.2013.10.025. [Epub ahead of print]
Epub:
Yes
Abstract:
In mammalian ES cells, the transcription factors Klf4 and Klf2 contribute to maintenance of pluripotency and self-renewal and...
Link:
http://www.sciencedirect.com/science/article/pii/S0012160613005800
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kotkamp K, Mössner R, Allen A, Onichtchouk D, Driever W. A Pou5f1/Oct4 dependent Klf2a, Klf2b, and Klf17 regulatory sub-network contributes to EVL and ectoderm development during zebrafish embryogenesis. Dev Biol. 2013 Nov 5. doi:pii: S0012-1606(13)00580-0. 10.1016/j.ydbio.2013.10.025. [Epub ahead of print].

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