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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl

Authors:
Zhu W, Pao GM, Satoh A, Cummings G, Monaghan JR, Harkins TT, Bryant SV, Voss SR, Gardiner DM, Hunter T
Citation:
Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.021
Epub:
Not Epub
Abstract:
The capacity for tissue and organ regeneration in humans is dwarfed by comparison to that of salamanders. Emerging evidence...
Delivery Method:
Injection
Organism or Cell Type:
Ambystoma mexicanum (axolotl)
Citation Extract:
Zhu W, Pao GM, Satoh A, Cummings G, Monaghan JR, Harkins TT, Bryant SV, Voss SR, Gardiner DM, Hunter T. Activation of germline-specific genes is required for limb regeneration in the Mexican axolotl. Dev Biol. 2012;[Epub ahead of print] doi:10.1016/j.ydbio.2012.07.021.

ALDH2 mediates 5-nitrofuran activity in multiple species

Authors:
Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, Westwood NJ, Patton EE.
Citation:
Chem Biol. 2012 Jul 27;19(7):883-92. doi: 10.1016/j.chembiol.2012.05.017.
Epub:
Not Epub
Abstract:
Understanding how drugs work in vivo is critical for drug design and for maximizing the potential of currently available drugs...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou L, Ishizaki H, Spitzer M, Taylor KL, Temperley ND, Johnson SL, Brear P, Gautier P, Zeng Z, Mitchell A, Narayan V, McNeil EM, Melton DW, Smith TK, Tyers M, Westwood NJ, Patton EE. . ALDH2 mediates 5-nitrofuran activity in multiple species. Chem Biol. 2012 Jul 27;19(7):883-92. doi: 10.1016/j.chembiol.2012.05.017..

An Anti-Apoptotic Role for Ornithine Decarboxylase during Oocyte Maturation

Authors:
Zhou Y, Ma C, Karmouch J, Arabi Katbi H, Liu XJ
Citation:
Mol Cell Biol. 2009 Jan 21. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Ornithine decarboxylase (ODC), the rate-limiting enzyme in polyamine biosynthesis, is a non-redundant and essential gene in all...
Delivery Method:
protecting metaphase II oocytes from reactive oxygen species-induced apoptosis."
Organism or Cell Type:
Microinjection
Citation Extract:
Zhou Y, Ma C, Karmouch J, Arabi Katbi H, Liu XJ. An Anti-Apoptotic Role for Ornithine Decarboxylase during Oocyte Maturation. Mol Cell Biol. 2009 Jan 21. [Epub ahead of print].

Chondrolectin Mediates Growth Cone Interactions of Motor Axons with an Intermediate Target

Authors:
Zhong Z, Ohnmacht J, Reimer MM, Bach I, Becker T, Becker CG
Citation:
J Neurosci. 2012;32(13):4426-4439. doi:10.1523/JNEUROSCI.5179-11.2012
Epub:
Not Epub
Abstract:
The C-type lectin chondrolectin (chodl) represents one of the major gene products dysregulated in spinal muscular atrophy...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhong Z, Ohnmacht J, Reimer MM, Bach I, Becker T, Becker CG. Chondrolectin Mediates Growth Cone Interactions of Motor Axons with an Intermediate Target. J Neurosci. 2012;32(13):4426-4439. doi:10.1523/JNEUROSCI.5179-11.2012 .

Circadian time-keeping during early stages of development

Authors:
Ziv L, Gothilf Y
Citation:
Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4146-51. Epub 2006 Mar 6
Epub:
Not Epub
Abstract:
The zebrafish pineal gland is a photoreceptive organ containing an intrinsic central circadian oscillator, which drives daily...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ziv L, Gothilf Y. Circadian time-keeping during early stages of development. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4146-51. Epub 2006 Mar 6.

Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes.

Authors:
Zhu Y, Rice CD, Pang Y, Pace M, Thomas P
Citation:
Proc Natl Acad Sci U S A 2003 Mar 4;100(5):2231-6
Epub:
Not Epub
Abstract:
The structures of membrane receptors mediating rapid, nongenomic actions of steroids have not been identified. We describe the...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhu Y, Rice CD, Pang Y, Pace M, Thomas P. Cloning, expression, and characterization of a membrane progestin receptor and evidence it is an intermediary in meiotic maturation of fish oocytes.. Proc Natl Acad Sci U S A 2003 Mar 4;100(5):2231-6.

Coagulation factor III (tissue factor) is required for vascularization in zebrafish embryos

Authors:
Zhou RF, Liu Y, Wang YX, Mo W, Yu M
Citation:
Genet. Mol. Res. 2011;[Epub ahead of print] doi:http://dx.doi.org/10.4238/2011.October.31.2
Epub:
Not Epub
Abstract:
Tissue factor (coagulation factor III) is a cell surface receptor for coagulation factor VII/VIIa; it was initially recognized...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou RF, Liu Y, Wang YX, Mo W, Yu M. Coagulation factor III (tissue factor) is required for vascularization in zebrafish embryos. Genet. Mol. Res. 2011;[Epub ahead of print] doi:http://dx.doi.org/10.4238/2011.October.31.2.

Dominant-negative C/ebpα and polycomb group protein Bmi1 extend short-lived hematopoietic stem/progenitor cell life span and induce lethal dyserythropoiesis

Authors:
Zhou T, Wang L, Zhu KY, Dong M, Xu PF, Chen Y, Chen SJ, Chen Z, Deng M, Liu TX
Citation:
Blood. 2011;118:3842-3852 doi:10.1182/blood-2010-12-327908
Epub:
Not Epub
Abstract:
The primitive hematopoietic stem/progenitor cells (HSPCs) during embryonic hematopoiesis are thought to be short-lived (SL)...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou T, Wang L, Zhu KY, Dong M, Xu PF, Chen Y, Chen SJ, Chen Z, Deng M, Liu TX. Dominant-negative C/ebpα and polycomb group protein Bmi1 extend short-lived hematopoietic stem/progenitor cell life span and induce lethal dyserythropoiesis. Blood. 2011;118:3842-3852 doi:10.1182/blood-2010-12-327908.

Elongation factor ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation

Authors:
Zhou J, Feng X, Ban B, Liu J, Wang Z, Xiao W
Citation:
J Biol Chem. 2009 Jul 10;284(28):19142-52. Epub 2009 May 15
Epub:
Not Epub
Abstract:
The eleven-nineteen lysine-rich leukemia (ELL) gene undergoes translocation and fuses in-frame to the multiple lineage leukemia...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou J, Feng X, Ban B, Liu J, Wang Z, Xiao W. Elongation factor ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation. J Biol Chem. 2009 Jul 10;284(28):19142-52. Epub 2009 May 15.

Endowing RNase H-Inactive Antisense with Catalytic Activity: 2-5A-Morphants.

Authors:
Zhou L, Civitello ER, Gupta N, Silverman RH, Molinaro RJ, Anderson DE, Torrence PF
Citation:
Bioconjug Chem. 2005 Mar 16;16(2):383-390
Epub:
Not Epub
Abstract:
A convergent synthetic approach was used to conjugate 2',5'-oligoadenylate (2-5A, p5'A2' [p5'A2...
Delivery Method:
not applicable
Organism or Cell Type:
not applicable
Citation Extract:
Zhou L, Civitello ER, Gupta N, Silverman RH, Molinaro RJ, Anderson DE, Torrence PF. Endowing RNase H-Inactive Antisense with Catalytic Activity: 2-5A-Morphants.. Bioconjug Chem. 2005 Mar 16;16(2):383-390.

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