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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells

Authors:
Buchholz B, Faria D, Schley G, Schreiber R, Eckardt KU, Kunzelmann K
Citation:
Kidney Int. 2013 Oct 23. doi: 10.1038/ki.2013.418. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Polycystic kidney diseases are characterized by multiple bilateral renal cysts that gradually enlarge and lead to a decline in...
Citation Extract:
Buchholz B, Faria D, Schley G, Schreiber R, Eckardt KU, Kunzelmann K. Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells. Kidney Int. 2013 Oct 23. doi: 10.1038/ki.2013.418. [Epub ahead of print] .

Developmental Expression of the Nfe2-Related Factor (Nrf) Transcription Factor Family in the Zebrafish, Danio rerio

Authors:
Williams LM, Timme-Laragy AR, Goldstone JV, McArthur AG, Stegeman JJ, Smolowitz RM, Hahn ME
Citation:
PLoS ONE. 2013;8(10):e79574. doi:10.1371/journal.pone.0079574
Epub:
Not Epub
Abstract:
Transcription factors in the CNC-bZIP family (NFE2, NRF1, NRF2 and NRF3) regulate genes with a wide range of functions in...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Williams LM, Timme-Laragy AR, Goldstone JV, McArthur AG, Stegeman JJ, Smolowitz RM, Hahn ME. Developmental Expression of the Nfe2-Related Factor (Nrf) Transcription Factor Family in the Zebrafish, Danio rerio. PLoS ONE. 2013;8(10):e79574. doi:10.1371/journal.pone.0079574 .

piezo2b Regulates Vertebrate Light Touch Response

Authors:
Faucherre A, Nargeot J, Mangoni ME, Jopling C
Citation:
J Neurosci. 2013 Oct 23;33(43):17089-94. doi: 10.1523/JNEUROSCI.0522-13.2013.
Epub:
Not Epub
Abstract:
The sense of touch allows an organism to detect and respond to physical environmental stimuli. Mechanosensitive proteins play a...
Organism or Cell Type:
Zebrafish
Citation Extract:
Faucherre A, Nargeot J, Mangoni ME, Jopling C. piezo2b Regulates Vertebrate Light Touch Response. J Neurosci. 2013 Oct 23;33(43):17089-94. doi: 10.1523/JNEUROSCI.0522-13.2013. .

A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression

Authors:
Langemeier J, Schrom EM, Rabner A, Radtke M, Zychlinski D, Saborowski A, Bohn G, Mandel-Gutfreund Y, Bodem J, Klein C, Bohne J
Citation:
EMBO J. 2012 Oct 17;31(20):4035-44. doi: 10.1038/emboj.2012.252. Epub 2012 Sep 11.
Epub:
Not Epub
Abstract:
Biallelic mutations in the untranslated regions (UTRs) of mRNAs are rare causes for monogenetic diseases whose mechanisms...
Delivery Method:
Electroporation (Neon microporator)
Organism or Cell Type:
Cell culture
Citation Extract:
Langemeier J, Schrom EM, Rabner A, Radtke M, Zychlinski D, Saborowski A, Bohn G, Mandel-Gutfreund Y, Bodem J, Klein C, Bohne J. A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression. EMBO J. 2012 Oct 17;31(20):4035-44. doi: 10.1038/emboj.2012.252. Epub 2012 Sep 11. .

Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions

Authors:
Bonventre JA, Kung TS, White LA, Cooper KR
Citation:
Toxicol Appl Pharmacol. 2013 Oct 12. doi:pii: S0041-008X(13)00439-0. 10.1016/j.taap.2013.10.008. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Methyl tert-butyl ether (MTBE) has been shown to be specifically anti-angiogenic in piscine and mammalian model systems at...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Bonventre JA, Kung TS, White LA, Cooper KR. Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions. Toxicol Appl Pharmacol. 2013 Oct 12. doi:pii: S0041-008X(13)00439-0. 10.1016/j.taap.2013.10.008. [Epub ahead of print] .

A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression

Authors:
Rösel-Hillgärtner TD, Hung L-H, Khrameeva E, Le Querrec P, Gelfand MS, Bindereif A
Citation:
PLoS Genet. 2013;9(10):e1003856. doi:10.1371/journal.pgen.1003856
Epub:
Not Epub
Abstract:
The U1 small nuclear ribonucleoprotein (snRNP)-specific U1C protein participates in 5' splice site recognition and...
Delivery Method:
electroporation
Organism or Cell Type:
cell culture: HeLa
Citation Extract:
Rösel-Hillgärtner TD, Hung L-H, Khrameeva E, Le Querrec P, Gelfand MS, Bindereif A. A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression. PLoS Genet. 2013;9(10):e1003856. doi:10.1371/journal.pgen.1003856 .

Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction

Authors:
Charvet B, Guiraud A, Malbouyres M, Zwolanek D, Guillon E, Bretaud S, Monnot C, Schulze J, Bader HL, Allard B, Koch M, Ruggiero F
Citation:
2013;[Epub ahead of print] doi:10.1242/dev.096024
Epub:
Not Epub
Abstract:
The myotendinous junction (MTJ) is the major site of force transfer in skeletal muscle, and defects in its structure correlate...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Charvet B, Guiraud A, Malbouyres M, Zwolanek D, Guillon E, Bretaud S, Monnot C, Schulze J, Bader HL, Allard B, Koch M, Ruggiero F. Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction. 2013;[Epub ahead of print] doi:10.1242/dev.096024 .

Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy

Authors:
Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U
Citation:
J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8
Epub:
Not Epub
Abstract:
In recent years, oligonucleotide-based molecules have been intensely used to modulate gene expression. All these molecules...
Delivery Method:
peptide
Organism or Cell Type:
cell culture
Citation Extract:
Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8.

eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation

Authors:
Yogev O, Williams VC, Hinits Y, Hughes SM
Citation:
PLoS Biol. 2013;11(10):e1001679. doi:10.1371/journal.pbio.1001679
Epub:
Not Epub
Abstract:
Muscle fiber size is activity-dependent and clinically important in ageing, bed-rest, and cachexia, where muscle weakening...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Yogev O, Williams VC, Hinits Y, Hughes SM. eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation. PLoS Biol. 2013;11(10):e1001679. doi:10.1371/journal.pbio.1001679 .

a2-Chimaerin Regulates a Key Axon Guidance Transition during Development of the Oculomotor Projection

Authors:
Clark C, Austen O, Poparic I, Guthrie S
Citation:
J Neurosci. 2013;33(42):16540-51. doi:10.1523/JNEUROSCI.1869-13.2013
Epub:
Not Epub
Abstract:
The ocular motor system consists of three nerves which innervate six muscles to control eye movements. In humans, defective...
Delivery Method:
microinjection
Organism or Cell Type:
Zebrafish
Citation Extract:
Clark C, Austen O, Poparic I, Guthrie S. a2-Chimaerin Regulates a Key Axon Guidance Transition during Development of the Oculomotor Projection. J Neurosci. 2013;33(42):16540-51. doi:10.1523/JNEUROSCI.1869-13.2013 .

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