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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
There are 12378 scientific papers returned from the database with the search filters currently being used below.
Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia
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Citation:
Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011 Epub:
Not Epub Abstract:
Most patients with acute lymphoblastic leukemia (ALL) fail current treatments highlighting the need for better therapies.... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Khandanpour C, Phelan JD, Vassen L, Schütte J, Chen R, Horman SR, Gaudreau MC, Krongold J, Zhu J, Paul WE, Dührsen U, Göttgens B, Grimes HL, Möröy T. Growth factor independence 1 antagonizes a p53-induced DNA damage response pathway in lymphoblastic leukemia. Cancer Cell. 2013 Feb 11;23(2):200-14. doi: 10.1016/j.ccr.2013.01.011. |
Electrophysiological Biomarkers in Spinal Muscular Atrophy: Preclinical Proof of Concept
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Citation:
Ann Clin Transl Neurol. 2014 Jan 1;1(1):34-44 Epub:
Not Epub Abstract:
Objective: Preclinical therapies that restore survival motor neuron (SMN) protein levels can dramatically extend survival in... Delivery Method:
intracerebroventricular injection Organism or Cell Type:
mouse Citation Extract: Arnold WD, Porensky PN, McGovern VL, Iyer CC, Duque S, Li X, Meyer K, Schmelzer L, Kaspar BK, Kolb SJ, Kissel JT, Burghes AH. Electrophysiological Biomarkers in Spinal Muscular Atrophy: Preclinical Proof of Concept. Ann Clin Transl Neurol. 2014 Jan 1;1(1):34-44. |
A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish
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Citation:
Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228 Epub:
Not Epub Abstract:
Dyskeratosis congenita (DC) is an inherited disorder with mutations affecting telomerase or telomeric proteins. DC patients... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Alcaraz-Pérez F, García-Castillo J, García-Moreno D, López-Muñoz A, Anchelin M, Angosto D, Zon LI, Mulero V, Cayuela ML. A non-canonical function of telomerase RNA in the regulation of developmental myelopoiesis in zebrafish. Nat Commun. 2014 Feb 5;5:3228. doi: 10.1038/ncomms4228. |
PCP and septins compartmentalize cortical actomyosin to direct collective cell movement
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Citation:
Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126 Epub:
Not Epub Abstract:
Despite our understanding of actomyosin function in individual migrating cells, we know little about the mechanisms by which... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Shindo A, Wallingford JB. PCP and septins compartmentalize cortical actomyosin to direct collective cell movement. Science. 2014 Feb 7;343(6171):649-52. doi: 10.1126/science.1243126. |
An essential role for LPA signalling in telencephalon development
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Citation:
Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901 Epub:
Not Epub Abstract:
Lysophosphatidic acid (LPA) has wide-ranging effects on many different cell types, acting through G-protein-coupled receptors... Delivery Method:
microinjection Organism or Cell Type:
Xenopus Citation Extract: Geach TJ, Faas L, Devader C, Gonzalez-Cordero A, Tabler JM, Brunsdon H, Isaacs HV, Dale L. An essential role for LPA signalling in telencephalon development. Development. 2014 Feb;141(4):940-9. doi: 10.1242/dev.104901. |
Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure
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Citation:
Dis Model Mech. 2013 Nov 7. [Epub ahead of print] Epub:
Yes Abstract:
An essential step in muscle fiber maturation is the assembly of highly ordered myofibrils that are required for contraction.... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Fero K, Bergeron SA, Horstick EJ, Codore H, Li GH, Ono F, Dowling JJ, Burgess HA. Impaired embryonic motility in dusp27 mutants reveals a developmental defect in myofibril structure. Dis Model Mech. 2013 Nov 7. [Epub ahead of print]. |
PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos
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Citation:
BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print] Epub:
Yes Abstract:
During Xenopus early development, FGF signaling is involved in mesoderm formation and neurogenesis by modulating various... Delivery Method:
microinjection Organism or Cell Type:
Xenopus laevis Citation Extract: Yoon J, Kim JH, Lee SY, Kim S, Park JB, Lee JY, Kim J. PV.1 induced by FGF-Xbra functions as a repressor of neurogenesis in Xenopus embryos. BMB Rep. 2014 Feb 6. pii: 2608. [Epub ahead of print]. |
Differential Skeletal Muscle Proteome of High and Low Active mice
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Citation:
J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print] Epub:
Yes Abstract:
Physical inactivity contributes to cardiovascular disease, type II diabetes, obesity and some types of cancer. While the... Delivery Method:
Vivo-Morpholino Organism or Cell Type:
mouse Citation Extract: Ferguson DP, Dangott LJ, Schmitt EE, Vellers HL, Lightfoot JT. Differential Skeletal Muscle Proteome of High and Low Active mice. J Appl Physiol. 1985. 2014 Feb 6. [Epub ahead of print]. |
Expression and function of transcription factor cMyb during cranial neural crest development
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Citation:
Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005 Epub:
Yes Abstract:
The transcription factor cMyb has well known functions in vertebrate hematopoiesis, but little was known about its distribution... Organism or Cell Type:
chick Citation Extract: Betancur P, Simões-Costa M, Sauka-Spengler T, Bronner ME. Expression and function of transcription factor cMyb during cranial neural crest development. Mech Dev. 2014;[Epub ahead of print] doi:10.1016/j.mod.2014.01.005. |
The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development
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Citation:
PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086 Epub:
Not Epub Abstract:
The Caenorhabditis elegans heterochronic gene pathway, which consists of a set of regulatory genes, plays an important... Delivery Method:
microinjection Organism or Cell Type:
zebrafish Citation Extract: Ouchi Y, Yamamoto J, Iwamoto T. The Heterochronic Genes lin-28a and lin-28b Play an Essential and Evolutionarily Conserved Role in Early Zebrafish Development. PLoS ONE. 2014;9(2):e88086. doi:10.1371/journal.pone.0088086. |