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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12378 scientific papers returned from the database with the search filters currently being used below.

Eph-Ephrin signaling and focal adhesion kinase regulate actomyosin-dependent apical constriction of ciliary band cells

Authors:
Krupke OA, Burke RD
Citation:
Development. 2014 Mar;141(5):1075-84. doi: 10.1242/dev.100123
Epub:
Not Epub
Abstract:
Apical constriction typically accompanies inward folding of an epithelial sheet. In recent years there has been progress in...
Link:
http://dev.biologists.org/content/141/5/1075.abstract
Delivery Method:
microinjection
Organism or Cell Type:
sea urchin
Citation Extract:
Krupke OA, Burke RD. Eph-Ephrin signaling and focal adhesion kinase regulate actomyosin-dependent apical constriction of ciliary band cells. Development. 2014 Mar;141(5):1075-84. doi: 10.1242/dev.100123.

Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2

Authors:
Zhou Q, Yang D, Ombrello AK, Zavialov AV, Toro C, Zavialov AV, Stone DL, Chae JJ, Rosenzweig SD, Bishop K, Barron KS, Kuehn HS, Hoffmann P, Negro A, Tsai WL, Cowen EW, Pei W, Milner JD, Silvin C, Heller T, Chin DT, Patronas NJ, Barber JS, Lee C-CR, Wood GM, Ling A, Kelly SJ, Kleiner DE, Mullikin JC, Ganson NJ, Kong HH, Hambleton S, Candotti F, Quezado MM, Calvo KR, Alao H, Barham BK, Jones A, Meschia JF, Worrall BB, Kasner SE, Rich SS, Goldbach-Mansky R, Abinun M, Chalom E, Gotte AC, Punaro M, Pascual V, Verbsky JW, Torgerson TR, Singer NG, Gershon TR, Ozen S, Karadag O, Fleisher TA, Remmers EF, Burgess SM, Moir SL, Gadina M, Sood R, Hershfield MS, Boehm M, Kastner DL, Aksentijevich I
Citation:
N Engl J Med. 2014 Mar 6;370(10):911-20. doi: 10.1056/NEJMoa1307361. Epub 2014 Feb 19.
Epub:
Yes
Abstract:
Background: We observed a syndrome of intermittent fevers, early-onset lacunar strokes and other neurovascular manifestations,...
Link:
http://www.nejm.org/doi/full/10.1056/NEJMoa1307361#t=abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Q, Yang D, Ombrello AK, Zavialov AV, Toro C, Zavialov AV, Stone DL, Chae JJ, Rosenzweig SD, Bishop K, Barron KS, Kuehn HS, Hoffmann P, Negro A, Tsai WL, Cowen EW, Pei W, Milner JD, Silvin C, Heller T, Chin DT, Patronas NJ, Barber JS, Lee C-CR, Wood GM, Ling A, Kelly SJ, Kleiner DE, Mullikin JC, Ganson NJ, Kong HH, Hambleton S, Candotti F, Quezado MM, Calvo KR, Alao H, Barham BK, Jones A, Meschia JF, Worrall BB, Kasner SE, Rich SS, Goldbach-Mansky R, Abinun M, Chalom E, Gotte AC, Punaro M, Pascual V, Verbsky JW, Torgerson TR, Singer NG, Gershon TR, Ozen S, Karadag O, Fleisher TA, Remmers EF, Burgess SM, Moir SL, Gadina M, Sood R, Hershfield MS, Boehm M, Kastner DL, Aksentijevich I. Early-Onset Stroke and Vasculopathy Associated with Mutations in ADA2. N Engl J Med. 2014 Mar 6;370(10):911-20. doi: 10.1056/NEJMoa1307361. Epub 2014 Feb 19..

Two independent transcription initiation codes overlap on vertebrate core promoters

Authors:
Haberle V, Li N, Hadzhiev Y, Plessy C, Previti C, Nepal C, Gehrig J, Dong X, Akalin A, Suzuki AM, van Ijcken WF, Armant O, Ferg M, Strähle U, Carninci P, Müller F, Lenhard B
Citation:
Nature. 2014 Feb 16. doi: 10.1038/nature12974. [Epub ahead of print]
Epub:
Yes
Abstract:
A core promoter is a stretch of DNA surrounding the transcription start site (TSS) that integrates regulatory inputs and...
Link:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature12974.html
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Haberle V, Li N, Hadzhiev Y, Plessy C, Previti C, Nepal C, Gehrig J, Dong X, Akalin A, Suzuki AM, van Ijcken WF, Armant O, Ferg M, Strähle U, Carninci P, Müller F, Lenhard B. Two independent transcription initiation codes overlap on vertebrate core promoters. Nature. 2014 Feb 16. doi: 10.1038/nature12974. [Epub ahead of print].

Upregulation of proteasome activity rescues cardiomyocytes following pulse treatment with a proteasome inhibitor

Authors:
Wang P, Calise J, Powell K, Divald A, Powell SR
Citation:
Am J Cardiovasc Dis. 2014 Jan 15;4(1):6-13. eCollection 2014
Epub:
Not Epub
Abstract:
This study examined the hypothesis that cardiomyocyte metabolism is inherently linked to the Ubiquitin Proteasome System. Rat...
Link:
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925881/
Delivery Method:
Endo-Porter
Organism or Cell Type:
cell culture: rat neonatal cardiomyocytes
Citation Extract:
Wang P, Calise J, Powell K, Divald A, Powell SR. Upregulation of proteasome activity rescues cardiomyocytes following pulse treatment with a proteasome inhibitor. Am J Cardiovasc Dis. 2014 Jan 15;4(1):6-13. eCollection 2014.

Bridging integrator 1 (Bin1) deficiency in zebrafish results in centronuclear myopathy

Authors:
Smith LL, Gupta VA, Beggs AH
Citation:
Hum Mol Genet. 2014 Feb 18. [Epub ahead of print]
Epub:
Yes
Abstract:
Autosomal recessive centronuclear myopathy (CNM2), caused by mutations in bridging integrator 1 (BIN1), is a mildly progressive...
Link:
http://hmg.oxfordjournals.org/content/early/2014/02/18/hmg.ddu067.abstract
Organism or Cell Type:
zebrafish
Citation Extract:
Smith LL, Gupta VA, Beggs AH. Bridging integrator 1 (Bin1) deficiency in zebrafish results in centronuclear myopathy. Hum Mol Genet. 2014 Feb 18. [Epub ahead of print].

Zebrafish tissue injury causes up-regulation of interleukin-1 and caspase dependent amplification of the inflammatory response

Authors:
Ogryzko NV, Hoggett EE, Solaymani-Kohal S, Tazzyman S, Chico TJ, Renshaw SA, Wilson HL
Citation:
Dis Model Mech. 2013 Nov 7. [Epub ahead of print]
Epub:
Yes
Abstract:
Interleukin-1, the 'gate-keeper' of inflammation, is the apical cytokine in a signalling cascade that drives the...
Link:
http://dmm.biologists.org/content/7/2/259.long
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Ogryzko NV, Hoggett EE, Solaymani-Kohal S, Tazzyman S, Chico TJ, Renshaw SA, Wilson HL. Zebrafish tissue injury causes up-regulation of interleukin-1 and caspase dependent amplification of the inflammatory response. Dis Model Mech. 2013 Nov 7. [Epub ahead of print].

Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis

Authors:
Manavski Y, Carmona G, Bennewitz K, Tang Z, Zhang F, Sakurai A, Zeiher AM, Gutkind JS, Li X, Kroll J, Dimmeler S, Chavakis E
Citation:
Basic Res Cardiol. 2014 Mar;109(2):404. doi: 10.1007/s00395-014-0404-2. Epub 2014 Feb 13.
Epub:
Not Epub
Abstract:
β1-Integrins are essential for angiogenesis. The mechanisms regulating integrin function in endothelial cells (EC) and their...
Link:
http://link.springer.com/article/10.1007%2Fs00395-014-0404-2
Organism or Cell Type:
zebrafish
Citation Extract:
Manavski Y, Carmona G, Bennewitz K, Tang Z, Zhang F, Sakurai A, Zeiher AM, Gutkind JS, Li X, Kroll J, Dimmeler S, Chavakis E. Brag2 differentially regulates β1- and β3-integrin-dependent adhesion in endothelial cells and is involved in developmental and pathological angiogenesis. Basic Res Cardiol. 2014 Mar;109(2):404. doi: 10.1007/s00395-014-0404-2. Epub 2014 Feb 13..

Posttranscriptional Control of the Stem Cell and Neurogenic Programs by the Nonsense-Mediated RNA Decay Pathway

Authors:
Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF
Citation:
Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.01.028
Epub:
Yes
Abstract:
The mechanisms dictating whether a cell proliferates or differentiates have undergone intense scrutiny, but they remain poorly...
Link:
https://www.cell.com/cell-reports/fulltext/S2211-1247(14)00045-X
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF. Posttranscriptional Control of the Stem Cell and Neurogenic Programs by the Nonsense-Mediated RNA Decay Pathway. Cell Rep. 2014;[Epub ahead of print] doi:10.1016/j.celrep.2014.01.028.

Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors

Authors:
Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF
Citation:
Science. 2014 Jan 9. [Epub ahead of print] doi:0.1126/science.1248636
Epub:
Yes
Abstract:
It has been assumed that most, if not all, signals regulating early development have been identified. Contrary to this...
Link:
http://www.sciencemag.org/content/343/6172/1248636.abstract
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Pauli A, Norris ML, Valen E, Chew GL, Gagnon JA, Zimmerman S, Mitchell A, Ma J, Dubrulle J, Reyon D, Tsai SQ, Joung JK, Saghatelian A, Schier AF. Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors. Science. 2014 Jan 9. [Epub ahead of print] doi:0.1126/science.1248636 .

The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome

Authors:
Chamling X, Seo S, Searby CC, Kim G, Slusarski DC, Sheffield VC
Citation:
PLoS Genet. 2014;10(2):e1004083. doi:10.1371/journal.pgen.1004083
Epub:
Not Epub
Abstract:
Bardet-Biedl syndrome (BBS) is a well-known ciliopathy with mutations reported in 18 different genes. Most of the protein...
Link:
http://www.plosgenetics.org/article/info%3Adoi%2F10.1371%2Fjournal.pgen.1004083
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Chamling X, Seo S, Searby CC, Kim G, Slusarski DC, Sheffield VC. The Centriolar Satellite Protein AZI1 Interacts with BBS4 and Regulates Ciliary Trafficking of the BBSome. PLoS Genet. 2014;10(2):e1004083. doi:10.1371/journal.pgen.1004083.

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