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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12143 scientific papers returned from the database with the search filters currently being used below.

Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning

Authors:
Yankura KA, Koechlein CS, Cryan AF, Cheatle A, Hinman VF
Citation:
Proc Natl Acad Sci U S A. 2013 May 21;110(21):8591-6. doi: 10.1073/pnas.1220903110. Epub 2013 May 6
Epub:
Not Epub
Abstract:
A great challenge in development biology is to understand how interacting networks of regulatory genes can direct the often...
Delivery Method:
microinjection
Organism or Cell Type:
sea star Patiria miniata
Citation Extract:
Yankura KA, Koechlein CS, Cryan AF, Cheatle A, Hinman VF. Gene regulatory network for neurogenesis in a sea star embryo connects broad neural specification and localized patterning. Proc Natl Acad Sci U S A. 2013 May 21;110(21):8591-6. doi: 10.1073/pnas.1220903110. Epub 2013 May 6.

Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish

Authors:
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ
Citation:
Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5
Epub:
Not Epub
Abstract:
Multiple signaling pathways control the specification of endothelial cells (ECs) to become arteries or veins during vertebrate...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilkinson RN, Koudijs MJ, Patient RK, Ingham PW, Schulte-Merker S, van Eeden FJ. Hedgehog signaling via a calcitonin receptor-like receptor can induce arterial differentiation independently of VEGF signaling in zebrafish. Blood. 2012 Jul 12;120(2):477-88. doi: 10.1182/blood-2011-10-383729. Epub 2012 Jun 5.

miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos

Authors:
Lin CY, Lee HC, Fu CY, Ding YY, Chen JS, Lee MH, Huang WJ, Tsai HJ
Citation:
Nat Commun. 2013 Nov 22;4:2829. doi: 10.1038/ncomms3829
Epub:
Not Epub
Abstract:
As miR-1 and miR-206 share identical seed sequences, they are commonly speculated to target the same gene. Here, we identify an...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lin CY, Lee HC, Fu CY, Ding YY, Chen JS, Lee MH, Huang WJ, Tsai HJ. miR-1 and miR-206 target different genes to have opposing roles during angiogenesis in zebrafish embryos. Nat Commun. 2013 Nov 22;4:2829. doi: 10.1038/ncomms3829.

Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis

Authors:
Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B
Citation:
J Biol Chem. 2013 Oct 8. [Epub ahead of print]
Epub:
Yes
Abstract:
The Hippo tumor suppressor pathway plays important roles in organ size control through Lats1/2 mediated phosphorylation of the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B. Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration and angiogenesis. J Biol Chem. 2013 Oct 8. [Epub ahead of print].

The role of cAMP-mediated intracellular signaling in regulating Na+ uptake in zebrafish larvae

Authors:
Kumai Y, Kwong RW, Perry SF
Citation:
Am J Physiol Regul Integr Comp Physiol. 2014 Jan 1;306(1):R51-60. doi: 10.1152/ajpregu.00317.2013. Epub 2013 Nov 20
Epub:
Not Epub
Abstract:
In the current study, the role of cAMP in stimulating Na+ uptake in larval zebrafish was investigated. Treating larvae at 4...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Kumai Y, Kwong RW, Perry SF . The role of cAMP-mediated intracellular signaling in regulating Na+ uptake in zebrafish larvae. Am J Physiol Regul Integr Comp Physiol. 2014 Jan 1;306(1):R51-60. doi: 10.1152/ajpregu.00317.2013. Epub 2013 Nov 20.

Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling

Authors:
Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W
Citation:
Blood. 2013 Jul 25. [Epub ahead of print]
Epub:
Yes
Abstract:
Establishment and stabilization of endothelial tubes with patent lumens is vital during vertebrate development. Ras-interacting...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Wilson CW, Parker LH, Hall CJ, Smyczek T, Mak J, Crow A, Posthuma G, De Mazière A, Sagolla M, Chalouni C, Vitorino P, Roose-Girma M, Warming S, Klumperman J, Crosier PS, Ye W. Rasip1 regulates vertebrate vascular endothelial junction stability through Epac1-Rap1 signaling. Blood. 2013 Jul 25. [Epub ahead of print].

Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish

Authors:
Lien H-W, Yang C-H, Cheng C-H, Liao Y-F, Han Y-S, Huang C-J
Citation:
Biochem Biophys Res Comm. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbrc.2013.11.042
Epub:
Yes
Abstract:
Zebrafish synuclein-γ2 (sncgb) has been reported to be expressed specifically in the notochord. However, the mechanism by which...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Lien H-W, Yang C-H, Cheng C-H, Liao Y-F, Han Y-S, Huang C-J. Zinc finger protein 219-like (ZNF219L) and Sox9a regulate synuclein-γ2 (sncgb) expression in the developing notochord of zebrafish. Biochem Biophys Res Comm. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.bbrc.2013.11.042.

Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration

Authors:
Ton QV, Iovine MK
Citation:
PLoS ONE. 2013;8(11):e81240. doi:10.1371/journal.pone.0081240
Epub:
Not Epub
Abstract:
Joints are essential for skeletal flexibly and form, yet the process underlying joint morphogenesis is poorly understood....
Delivery Method:
injection then electroporation
Organism or Cell Type:
zebrafish
Citation Extract:
Ton QV, Iovine MK. Identification of an evx1-Dependent Joint-Formation Pathway during FIN Regeneration. PLoS ONE. 2013;8(11):e81240. doi:10.1371/journal.pone.0081240.

Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice

Authors:
Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T
Citation:
Int J Obes (Lond). 2013 Nov 20. doi: 10.1038/ijo.2013.217. [Epub ahead of print]
Epub:
Yes
Abstract:
Background:The diet-induced obesity model of zebrafish (DIO-zebrafish) shares a common pathophysiological pathway with...
Delivery Method:
i.p. injection
Organism or Cell Type:
zebrafish
Citation Extract:
Shimada Y, Kuroyanagi J, Zhang B, Ariyoshi M, Umemoto N, Nishimura Y, Tanaka T. Downregulation of max dimerization protein 3 is involved in decreased visceral adipose tissue by inhibiting adipocyte differentiation in zebrafish and mice. Int J Obes (Lond). 2013 Nov 20. doi: 10.1038/ijo.2013.217. [Epub ahead of print].

A time delay gene circuit is required for palp formation in the ascidian embryo

Authors:
Ikeda T, Matsuoka T, Satou Y
Citation:
Development. 2013;140:4703-8. doi:10.1242/dev.100339
Epub:
Not Epub
Abstract:
The ascidian larval brain and palps (a putative rudimentary placode) are specified by two transcription factor genes, ZicL and...
Delivery Method:
microinjection
Organism or Cell Type:
Ciona intestinalis
Citation Extract:
Ikeda T, Matsuoka T, Satou Y. A time delay gene circuit is required for palp formation in the ascidian embryo. Development. 2013;140:4703-8. doi:10.1242/dev.100339.

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