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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

Haploinsufficiency of TAB2 causes congenital heart defects in humans

Authors:
Thienpont B, Zhang L, Postma AV, Breckpot J, Tranchevent LC, Van Loo P, Møllgård K, Tommerup N, Bache I, Tümer Z, van Engelen K, Menten B, Mortier G, Waggoner D, Gewillig M, Moreau Y, Devriendt K, Larsen LA
Citation:
Am J Hum Genet. 2010 Jun 11;86(6):839-49. doi: 10.1016/j.ajhg.2010.04.011. Epub 2010 May 20
Epub:
Yes
Abstract:
Congenital heart defects (CHDs) are the most common major developmental anomalies and the most frequent cause for perinatal...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Thienpont B, Zhang L, Postma AV, Breckpot J, Tranchevent LC, Van Loo P, Møllgård K, Tommerup N, Bache I, Tümer Z, van Engelen K, Menten B, Mortier G, Waggoner D, Gewillig M, Moreau Y, Devriendt K, Larsen LA. Haploinsufficiency of TAB2 causes congenital heart defects in humans. Am J Hum Genet. 2010 Jun 11;86(6):839-49. doi: 10.1016/j.ajhg.2010.04.011. Epub 2010 May 20.

Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development

Authors:
Miyamoto K, Teperek M, Yusa K, Allen GE, Bradshaw CR, Gurdon JB
Citation:
Science. 2013 Aug 30;341(6149):1002-5. doi: 10.1126/science.1240376
Epub:
Yes
Abstract:
Eggs and oocytes have a remarkable ability to induce transcription of sperm after normal fertilization and in somatic nuclei...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Miyamoto K, Teperek M, Yusa K, Allen GE, Bradshaw CR, Gurdon JB. Nuclear Wave1 is required for reprogramming transcription in oocytes and for normal development. Science. 2013 Aug 30;341(6149):1002-5. doi: 10.1126/science.1240376.

Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion

Authors:
Moore R, Theveneau E, Pozzi S, Alexandre P, Richardson J, Merks A, Parsons M, Kashef J, Linker C, Mayor R
Citation:
Development. 2013 Oct 30. [Epub ahead of print]
Epub:
Yes
Abstract:
There is growing evidence that contact inhibition of locomotion (CIL) is essential for morphogenesis and its failure is thought...
Organism or Cell Type:
Xenopus and zebrafish
Citation Extract:
Moore R, Theveneau E, Pozzi S, Alexandre P, Richardson J, Merks A, Parsons M, Kashef J, Linker C, Mayor R. Par3 controls neural crest migration by promoting microtubule catastrophe during contact inhibition of locomotion. Development. 2013 Oct 30. [Epub ahead of print].

Antibiotics Present and Future

Authors:
Altman S
Citation:
FEBS Letters. 2013;[Epub ahead of print] doi:10.1016/j.febslet.2013.10.048
Epub:
Not Epub
Abstract:
Here we make a brief survey of the present state of antibiotic research and use. We also describe a novel antibiotic that...
Delivery Method:
peptide-linked
Organism or Cell Type:
Plasmodium falciparum, bacteria
Citation Extract:
Altman S. Antibiotics Present and Future. FEBS Letters. 2013;[Epub ahead of print] doi:10.1016/j.febslet.2013.10.048.

The Xenopus homeobox gene pitx3 impinges upon somitogenesis and laterality

Authors:
Smoczer C, Hooker L, Brode S, Wolanski M, KhosrowShahian F, Crawford M
Citation:
Biochem Cell Biol. 2013 Apr;91(2):79-87. doi: 10.1139/bcb-2012-0057. Epub 2012 Nov 9
Epub:
Not Epub
Abstract:
Pitx3 has been identified as the causative locus in a developmental eye mutation associated with mammalian anterior segment...
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus
Citation Extract:
Smoczer C, Hooker L, Brode S, Wolanski M, KhosrowShahian F, Crawford M. The Xenopus homeobox gene pitx3 impinges upon somitogenesis and laterality. Biochem Cell Biol. 2013 Apr;91(2):79-87. doi: 10.1139/bcb-2012-0057. Epub 2012 Nov 9.

Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish

Authors:
Yin W, Hu B
Citation:
Exp Neurol. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.expneurol.2013.11.012
Epub:
Yes
Abstract:
Demyelinating diseases include multiple sclerosis, which is a neurodegenerative disease characterized by immune attacks on the...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Yin W, Hu B. Knockdown of Lingo1b protein promotes myelination and oligodendrocyte differentiation in zebrafish. Exp Neurol. 2013;[Epub ahead of print] http://dx.doi.org/10.1016/j.expneurol.2013.11.012.

A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality

Authors:
Noël ES, Verhoeven M, Lagendijk AK, Tessadori F, Smith K, Choorapoikayil S, den Hertog J, Bakkers J
Citation:
Nat Commun. 2013 Nov 11;4:2754. doi: 10.1038/ncomms3754
Epub:
Yes
Abstract:
Breaking left-right symmetry in bilateria is a major event during embryo development that is required for asymmetric organ...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Noël ES, Verhoeven M, Lagendijk AK, Tessadori F, Smith K, Choorapoikayil S, den Hertog J, Bakkers J. A Nodal-independent and tissue-intrinsic mechanism controls heart-looping chirality. Nat Commun. 2013 Nov 11;4:2754. doi: 10.1038/ncomms3754.

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Authors:
Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, Yeo GW
Citation:
Nat Struct Mol Biol. 2013 Nov 10. doi: 10.1038/nsmb.2699. [Epub ahead of print]
Epub:
Yes
Abstract:
Alternative splicing (AS) enables programmed diversity of gene expression across tissues and development. We show here that...
Delivery Method:
Vivo-Morpholino in vivo, Endo-Porter in culture
Organism or Cell Type:
mouse, cell culture: HS578T cells
Citation Extract:
Lovci MT, Ghanem D, Marr H, Arnold J, Gee S, Parra M, Liang TY, Stark TJ, Gehman LT, Hoon S, Massirer KB, Pratt GA, Black DL, Gray JW, Conboy JG, Yeo GW. Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges. Nat Struct Mol Biol. 2013 Nov 10. doi: 10.1038/nsmb.2699. [Epub ahead of print].

Directional tissue migration through a self-generated chemokine gradient

Authors:
Donà E, Barry JD, Valentin G, Quirin C, Khmelinskii A, Kunze A, Durdu S, Newton LR, Fernandez-Minan A, Huber W, Knop M, Gilmour D
Citation:
Nature. 2013 Nov 14;503(7475):285-9. doi: 10.1038/nature12635. Epub 2013 Sep 25
Epub:
Not Epub
Abstract:
The directed migration of cell collectives is a driving force of embryogenesis. The predominant view in the field is that cells...
Delivery Method:
microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Donà E, Barry JD, Valentin G, Quirin C, Khmelinskii A, Kunze A, Durdu S, Newton LR, Fernandez-Minan A, Huber W, Knop M, Gilmour D. Directional tissue migration through a self-generated chemokine gradient. Nature. 2013 Nov 14;503(7475):285-9. doi: 10.1038/nature12635. Epub 2013 Sep 25.

The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality

Authors:
Boskovski MT, Yuan S, Pedersen NB, Goth CK, Makova S, Clausen H, Brueckner M, Khokha MK
Citation:
Nature. 2013 Nov 13. doi: 10.1038/nature12723. [Epub ahead of print]
Epub:
Yes
Abstract:
Heterotaxy is a disorder of left-right body patterning, or laterality, that is associated with major congenital heart disease....
Delivery Method:
microinjection
Organism or Cell Type:
Xenopus tropicalis
Citation Extract:
Boskovski MT, Yuan S, Pedersen NB, Goth CK, Makova S, Clausen H, Brueckner M, Khokha MK. The heterotaxy gene GALNT11 glycosylates Notch to orchestrate cilia type and laterality. Nature. 2013 Nov 13. doi: 10.1038/nature12723. [Epub ahead of print].

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