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Morpholino Publication Database
This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.
There are 12165 scientific papers returned from the database with the search filters currently being used below.
There are 12165 scientific papers returned from the database with the search filters currently being used below.
A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression
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Citation:
EMBO J. 2012 Oct 17;31(20):4035-44. doi: 10.1038/emboj.2012.252. Epub 2012 Sep 11. Epub:
Not Epub Abstract:
Biallelic mutations in the untranslated regions (UTRs) of mRNAs are rare causes for monogenetic diseases whose mechanisms... Delivery Method:
Electroporation (Neon microporator) Organism or Cell Type:
Cell culture Citation Extract: Langemeier J, Schrom EM, Rabner A, Radtke M, Zychlinski D, Saborowski A, Bohn G, Mandel-Gutfreund Y, Bodem J, Klein C, Bohne J. A complex immunodeficiency is based on U1 snRNP-mediated poly(A) site suppression. EMBO J. 2012 Oct 17;31(20):4035-44. doi: 10.1038/emboj.2012.252. Epub 2012 Sep 11. . |
Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions
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Citation:
Toxicol Appl Pharmacol. 2013 Oct 12. doi:pii: S0041-008X(13)00439-0. 10.1016/j.taap.2013.10.008. [Epub ahead of print] Epub:
Not Epub Abstract:
Methyl tert-butyl ether (MTBE) has been shown to be specifically anti-angiogenic in piscine and mammalian model systems at... Delivery Method:
microinjection Organism or Cell Type:
Zebrafish Citation Extract: Bonventre JA, Kung TS, White LA, Cooper KR. Manipulation of the HIF-Vegf pathway rescues methyl tert-butyl ether (MTBE)-induced vascular lesions. Toxicol Appl Pharmacol. 2013 Oct 12. doi:pii: S0041-008X(13)00439-0. 10.1016/j.taap.2013.10.008. [Epub ahead of print] . |
A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression
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Citation:
PLoS Genet. 2013;9(10):e1003856. doi:10.1371/journal.pgen.1003856 Epub:
Not Epub Abstract:
The U1 small nuclear ribonucleoprotein (snRNP)-specific U1C protein participates in 5' splice site recognition and... Delivery Method:
electroporation Organism or Cell Type:
cell culture: HeLa Citation Extract: Rösel-Hillgärtner TD, Hung L-H, Khrameeva E, Le Querrec P, Gelfand MS, Bindereif A. A Novel Intra-U1 snRNP Cross-Regulation Mechanism: Alternative Splicing Switch Links U1C and U1-70K Expression. PLoS Genet. 2013;9(10):e1003856. doi:10.1371/journal.pgen.1003856 . |
Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction
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Citation:
2013;[Epub ahead of print] doi:10.1242/dev.096024 Epub:
Not Epub Abstract:
The myotendinous junction (MTJ) is the major site of force transfer in skeletal muscle, and defects in its structure correlate... Delivery Method:
microinjection Organism or Cell Type:
Zebrafish Citation Extract: Charvet B, Guiraud A, Malbouyres M, Zwolanek D, Guillon E, Bretaud S, Monnot C, Schulze J, Bader HL, Allard B, Koch M, Ruggiero F. Knockdown of col22a1 gene in zebrafish induces a muscular dystrophy by disruption of the myotendinous junction. 2013;[Epub ahead of print] doi:10.1242/dev.096024 . |
Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy
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Citation:
J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8 Epub:
Not Epub Abstract:
In recent years, oligonucleotide-based molecules have been intensely used to modulate gene expression. All these molecules... Delivery Method:
peptide Organism or Cell Type:
cell culture Citation Extract: Lehto T, Abes R, Oskolkov N, Suhorutsenko J, Copolovici DM, Mäger I, Viola JR, Simonson OE, Ezzat K, Guterstam P, Eriste E, Smith CI, Lebleu B, Samir El Andaloussi, Langel U. Delivery of nucleic acids with a stearylated (RxR)4 peptide using a non-covalent co-incubation strategy. J Control Release. 2010 Jan 4;141(1):42-51. doi: 10.1016/j.jconrel.2009.08.028. Epub 2009 Sep 8. |
eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation
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Citation:
PLoS Biol. 2013;11(10):e1001679. doi:10.1371/journal.pbio.1001679 Epub:
Not Epub Abstract:
Muscle fiber size is activity-dependent and clinically important in ageing, bed-rest, and cachexia, where muscle weakening... Delivery Method:
microinjection Organism or Cell Type:
Zebrafish Citation Extract: Yogev O, Williams VC, Hinits Y, Hughes SM. eIF4EBP3L Acts as a Gatekeeper of TORC1 In Activity-Dependent Muscle Growth by Specifically Regulating Mef2ca Translational Initiation. PLoS Biol. 2013;11(10):e1001679. doi:10.1371/journal.pbio.1001679 . |
a2-Chimaerin Regulates a Key Axon Guidance Transition during Development of the Oculomotor Projection
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Citation:
J Neurosci. 2013;33(42):16540-51. doi:10.1523/JNEUROSCI.1869-13.2013 Epub:
Not Epub Abstract:
The ocular motor system consists of three nerves which innervate six muscles to control eye movements. In humans, defective... Delivery Method:
microinjection Organism or Cell Type:
Zebrafish Citation Extract: Clark C, Austen O, Poparic I, Guthrie S. a2-Chimaerin Regulates a Key Axon Guidance Transition during Development of the Oculomotor Projection. J Neurosci. 2013;33(42):16540-51. doi:10.1523/JNEUROSCI.1869-13.2013 . |
Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent
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Citation:
Proc Natl Acad Sci U S A. 2013;110(2):16898-903. doi:10.1073/pnas.1304837110 Epub:
Not Epub Abstract:
Despite their abundance and multiple functions in a variety of organ systems, the function and signaling mechanisms of adhesion... Delivery Method:
microinjection Organism or Cell Type:
Zebrafish Citation Extract: Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Mühlfeld C, Engel FB. Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci U S A. 2013;110(2):16898-903. doi:10.1073/pnas.1304837110 . |
Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin. Development
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Citation:
2012 Oct;139(20):3786-94 Epub:
Not Epub Abstract:
The process of germ line determination involves many conserved genes, yet is highly variable. Echinoderms are positioned at the... Delivery Method:
microinjection Organism or Cell Type:
Sea urchin Strongylocentrotus purpuratus Citation Extract: Yajima M, Wessel GM. Autonomy in specification of primordial germ cells and their passive translocation in the sea urchin. Development. 2012 Oct;139(20):3786-94. |
tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches
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Citation:
PLoS ONE. 2013;8(10):e77171. doi:10.1371/journal.pone.0077171 Epub:
Not Epub Abstract:
Tbx2 is a member of the T-box family of transcription factors essential for embryo- and organogenesis. A deficiency in the... Delivery Method:
microinjection Organism or Cell Type:
Zebrafish Citation Extract: Thi Thu HN, Haw Tien SF, Loh SL, Bok Yan JS, Korzh V. tbx2a Is Required for Specification of Endodermal Pouches during Development of the Pharyngeal Arches. PLoS ONE. 2013;8(10):e77171. doi:10.1371/journal.pone.0077171 . |