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Morpholino Publication Database

This database contains citations and abstracts for research using Morpholino oligos, as well as some review articles incorporating Morpholino data. You can search the content using the filter boxes below.

There are 12138 scientific papers returned from the database with the search filters currently being used below.

FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair

Authors:
Zhou W, Otto EA, Cluckey A, Airik R, Hurd TW, Chaki M, Diaz K, Lach FP, Bennett GR, Gee HY, Ghosh AK, Natarajan S, Thongthip S, Veturi U, Allen SJ, Janssen S, Ramaswami G, Dixon J, Burkhalter F, Spoendlin M, Moch H, Mihatsch MJ, Verine J, Reade R, Soliman H, Godin M, Kiss D, Monga G, Mazzucco G, Amann K, Artunc F, Newland RC, Wiech T, Zschiedrich S, Huber TB, Friedl A, Slaats GG, Joles JA, Goldschmeding R, Washburn J, Giles RH, Levy S, Smogorzewska A, Hildebrandt F
Citation:
Nat Genet. 2012 Jul 8;44(8):910-5. doi: 10.1038/ng.2347
Epub:
Not Epub
Abstract:
Chronic kidney disease (CKD) represents a major health burden. Its central feature of renal fibrosis is not well understood. By...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou W, Otto EA, Cluckey A, Airik R, Hurd TW, Chaki M, Diaz K, Lach FP, Bennett GR, Gee HY, Ghosh AK, Natarajan S, Thongthip S, Veturi U, Allen SJ, Janssen S, Ramaswami G, Dixon J, Burkhalter F, Spoendlin M, Moch H, Mihatsch MJ, Verine J, Reade R, Soliman H, Godin M, Kiss D, Monga G, Mazzucco G, Amann K, Artunc F, Newland RC, Wiech T, Zschiedrich S, Huber TB, Friedl A, Slaats GG, Joles JA, Goldschmeding R, Washburn J, Giles RH, Levy S, Smogorzewska A, Hildebrandt F. FAN1 mutations cause karyomegalic interstitial nephritis, linking chronic kidney failure to defective DNA damage repair. Nat Genet. 2012 Jul 8;44(8):910-5. doi: 10.1038/ng.2347.

Functional development of the zebrafish pineal gland: light-induced expression of period2 is required for onset of the circadian clock

Authors:
Ziv L, Levkovitz S, Toyama R, Falcon J, Gothilf Y
Citation:
J Neuroendocrinol. 2005 May;17(5):314-20
Epub:
Not Epub
Abstract:
In zebrafish, the pineal gland is a photoreceptive organ that contains an intrinsic circadian oscillator and exhibits rhythmic...
Organism or Cell Type:
zebrafish
Citation Extract:
Ziv L, Levkovitz S, Toyama R, Falcon J, Gothilf Y. Functional development of the zebrafish pineal gland: light-induced expression of period2 is required for onset of the circadian clock. J Neuroendocrinol. 2005 May;17(5):314-20.

Histone deacetylase 1 is required for exocrine pancreatic epithelial proliferation in development and cancer

Authors:
Zhou W, Liang IC, Yee NS
Citation:
Cancer Biol Ther. 2011 Apr 1;11(7):659-70. Epub 2011 Apr 1
Epub:
Not Epub
Abstract:
Histone deacetylases (HDACs) play important roles in the epigenetic control of development, and aberrant expression of HDACs...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou W, Liang IC, Yee NS. Histone deacetylase 1 is required for exocrine pancreatic epithelial proliferation in development and cancer. Cancer Biol Ther. 2011 Apr 1;11(7):659-70. Epub 2011 Apr 1.

Identification and Ocular Expression of Zebrafish Laminin Alpha 1 Gene

Authors:
Zinkevich NS, Bosenko DV, Link BA, Semina EV
Citation:
Invest. Ophthalmol. Vis. Sci., May 2005; 46: 3122
Epub:
Not Epub
Abstract:
Purpose: To report a sequence and expression of zebrafish laminin alpha 1. Laminins are components of all basement membranes...
Delivery Method:
Not Specific
Organism or Cell Type:
zebrafish
Citation Extract:
Zinkevich NS, Bosenko DV, Link BA, Semina EV. Identification and Ocular Expression of Zebrafish Laminin Alpha 1 Gene. Invest. Ophthalmol. Vis. Sci., May 2005; 46: 3122.

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

Authors:
Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi JI, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I
Citation:
Nature. 2008 Jun 4. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Insulin-like growth-factor-binding proteins (IGFBPs) bind to and modulate the actions of insulin-like growth factors (IGFs)....
Organism or Cell Type:
Xenopus
Citation Extract:
Zhu W, Shiojima I, Ito Y, Li Z, Ikeda H, Yoshida M, Naito AT, Nishi JI, Ueno H, Umezawa A, Minamino T, Nagai T, Kikuchi A, Asashima M, Komuro I. IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis. Nature. 2008 Jun 4. [Epub ahead of print].

Integrin alpha 7 interacts with high temperature requirement A2 (HtrA2) to induce prostate cancer cell death

Authors:
Zhu ZH, Yu YP, Zheng ZL, Song Y, Xiang GS, Nelson J, Michalopoulos G, Luo JH
Citation:
Am J Pathol. 2010 Sep;177(3):1176-86. Epub 2010 Jul 22
Epub:
Not Epub
Abstract:
Integrins are a family of receptors for extracellular matrix proteins that have critical roles in human tissue development....
Delivery Method:
Electroporation
Organism or Cell Type:
cell culture: PITT1 (derived from PC-3 human prostate cancer cell line)
Citation Extract:
Zhu ZH, Yu YP, Zheng ZL, Song Y, Xiang GS, Nelson J, Michalopoulos G, Luo JH. Integrin alpha 7 interacts with high temperature requirement A2 (HtrA2) to induce prostate cancer cell death. Am J Pathol. 2010 Sep;177(3):1176-86. Epub 2010 Jul 22.

laminin alpha 1 gene is essential for normal lens development in zebrafish

Authors:
Zinkevich NS, Bosenko DV, Link BA, Semina EV
Citation:
BMC Dev Biol. 2006 Mar 7;6(1):13 [Epub ahead of print]
Epub:
Not Epub
Abstract:
Laminins represent major components of basement membranes and play various roles in embryonic and adult tissues. The functional...
Delivery Method:
Microinjection
Organism or Cell Type:
zebrafish
Citation Extract:
Zinkevich NS, Bosenko DV, Link BA, Semina EV. laminin alpha 1 gene is essential for normal lens development in zebrafish. BMC Dev Biol. 2006 Mar 7;6(1):13 [Epub ahead of print].

Latent TGF-β binding protein 3 identifies a second heart field in zebrafish

Authors:
Zhou Y, Cashman TJ, Nevis KR, Obregon P, Carney SA, Liu Y, Gu A, Mosimann C, Sondalle S, Peterson RE, Heideman W, Burns CE, Burns CG
Citation:
Nature. 2011 May 29. [Epub ahead of print]
Epub:
Not Epub
Abstract:
The four-chambered mammalian heart develops from two fields of cardiac progenitor cells distinguished by their spatiotemporal...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou Y, Cashman TJ, Nevis KR, Obregon P, Carney SA, Liu Y, Gu A, Mosimann C, Sondalle S, Peterson RE, Heideman W, Burns CE, Burns CG. Latent TGF-β binding protein 3 identifies a second heart field in zebrafish. Nature. 2011 May 29. [Epub ahead of print].

Macroscopic stiffening of embryonic tissues via microtubules, RhoGEF and the assembly of contractile bundles of actomyosin

Authors:
Zhou J, Kim HY, Wang JH, Davidson LA
Citation:
Development. 2010 Jul 14. [Epub ahead of print]
Epub:
Not Epub
Abstract:
During morphogenesis, forces generated by cells are coordinated and channeled by the viscoelastic properties of the embryo....
Organism or Cell Type:
Xenopus laevis
Citation Extract:
Zhou J, Kim HY, Wang JH, Davidson LA. Macroscopic stiffening of embryonic tissues via microtubules, RhoGEF and the assembly of contractile bundles of actomyosin. Development. 2010 Jul 14. [Epub ahead of print].

Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development

Authors:
Zhou H, Clapham DE
Citation:
Proc Natl Acad Sci U S A. 2009 Aug 26. [Epub ahead of print]
Epub:
Not Epub
Abstract:
Magnesium (Mg(2+)) is the second most abundant cation in cells, yet relatively few mechanisms have been identified that...
Organism or Cell Type:
zebrafish
Citation Extract:
Zhou H, Clapham DE. Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development. Proc Natl Acad Sci U S A. 2009 Aug 26. [Epub ahead of print].

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